Pacific Biosciences of California (PACB) Competitors $1.49 +0.06 (+4.20%) Closing price 10/3/2025 04:00 PM EasternExtended Trading$1.50 +0.01 (+0.34%) As of 10/3/2025 07:43 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock PACB vs. TXG, HBIO, TMO, A, MTD, WAT, ILMN, TECH, BIO, and CRLShould you be buying Pacific Biosciences of California stock or one of its competitors? The main competitors of Pacific Biosciences of California include 10x Genomics (TXG), Harvard Bioscience (HBIO), Thermo Fisher Scientific (TMO), Agilent Technologies (A), Mettler-Toledo International (MTD), Waters (WAT), Illumina (ILMN), Bio-Techne (TECH), Bio-Rad Laboratories (BIO), and Charles River Laboratories International (CRL). Pacific Biosciences of California vs. Its Competitors 10x Genomics Harvard Bioscience Thermo Fisher Scientific Agilent Technologies Mettler-Toledo International Waters Illumina Bio-Techne Bio-Rad Laboratories Charles River Laboratories International 10x Genomics (NASDAQ:TXG) and Pacific Biosciences of California (NASDAQ:PACB) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their risk, profitability, media sentiment, valuation, dividends, earnings, institutional ownership and analyst recommendations. Which has more risk and volatility, TXG or PACB? 10x Genomics has a beta of 2.05, indicating that its stock price is 105% more volatile than the S&P 500. Comparatively, Pacific Biosciences of California has a beta of 2.1, indicating that its stock price is 110% more volatile than the S&P 500. Do analysts recommend TXG or PACB? 10x Genomics presently has a consensus target price of $13.65, indicating a potential upside of 7.09%. Pacific Biosciences of California has a consensus target price of $1.90, indicating a potential upside of 27.52%. Given Pacific Biosciences of California's higher probable upside, analysts clearly believe Pacific Biosciences of California is more favorable than 10x Genomics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score 10x Genomics 2 Sell rating(s) 8 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 2.25Pacific Biosciences of California 1 Sell rating(s) 4 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 2.25 Is TXG or PACB more profitable? 10x Genomics has a net margin of -13.13% compared to Pacific Biosciences of California's net margin of -336.40%. 10x Genomics' return on equity of -12.88% beat Pacific Biosciences of California's return on equity.Company Net Margins Return on Equity Return on Assets 10x Genomics-13.13% -12.88% -10.03% Pacific Biosciences of California -336.40%-66.75%-16.90% Which has higher earnings & valuation, TXG or PACB? 10x Genomics has higher revenue and earnings than Pacific Biosciences of California. 10x Genomics is trading at a lower price-to-earnings ratio than Pacific Biosciences of California, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio10x Genomics$610.78M2.60-$182.63M-$0.70-18.21Pacific Biosciences of California$154.01M2.91-$309.85M-$2.29-0.65 Does the media refer more to TXG or PACB? In the previous week, 10x Genomics had 7 more articles in the media than Pacific Biosciences of California. MarketBeat recorded 9 mentions for 10x Genomics and 2 mentions for Pacific Biosciences of California. 10x Genomics' average media sentiment score of 0.77 beat Pacific Biosciences of California's score of 0.67 indicating that 10x Genomics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment 10x Genomics 4 Very Positive mention(s) 1 Positive mention(s) 4 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Pacific Biosciences of California 1 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do insiders & institutionals have more ownership in TXG or PACB? 84.7% of 10x Genomics shares are owned by institutional investors. 10.0% of 10x Genomics shares are owned by company insiders. Comparatively, 2.4% of Pacific Biosciences of California shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth. Summary10x Genomics beats Pacific Biosciences of California on 11 of the 15 factors compared between the two stocks. Get Pacific Biosciences of California News Delivered to You Automatically Sign up to receive the latest news and ratings for PACB and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding PACB and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart PACB vs. The Competition Export to ExcelMetricPacific Biosciences of CaliforniaMED INSTRUMENTS IndustryMedical SectorNASDAQ ExchangeMarket Cap$447.55M$7.15B$6.13B$10.58BDividend YieldN/A1.16%5.66%4.69%P/E Ratio-0.6527.5386.8826.70Price / Sales2.91199.31608.05229.32Price / CashN/A22.4126.3031.09Price / Book0.815.3012.536.57Net Income-$309.85M$178.04M$3.30B$276.78M7 Day Performance23.14%5.15%4.28%2.42%1 Month Performance17.32%10.26%6.90%8.63%1 Year Performance-13.37%29.73%70.54%31.60% Pacific Biosciences of California Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)PACBPacific Biosciences of California2.1278 of 5 stars$1.49+4.2%$1.90+27.5%-13.4%$447.55M$154.01M-0.65730TXG10x Genomics3.692 of 5 stars$11.34-3.2%$13.65+20.4%-36.3%$1.41B$644.47M-16.201,240News CoverageAnalyst UpgradeHBIOHarvard Bioscience4.3797 of 5 stars$0.44-0.9%$2.00+354.8%-81.3%$19.58M$94.14M-0.34490Positive NewsTMOThermo Fisher Scientific4.8669 of 5 stars$461.95-0.5%$588.35+27.4%-9.1%$174.44B$42.88B26.72125,000News CoveragePositive NewsAnalyst ForecastOptions VolumeAAgilent Technologies3.8234 of 5 stars$123.70+0.3%$140.08+13.2%-2.1%$35.07B$6.51B29.0417,900News CoverageEx-DividendAnalyst ForecastMTDMettler-Toledo International3.9525 of 5 stars$1,191.70-1.1%$1,325.56+11.2%-9.5%$24.55B$3.87B30.1817,300Positive NewsAnalyst ForecastWATWaters4.6078 of 5 stars$289.19-0.9%$378.73+31.0%-6.7%$17.21B$2.96B26.087,600Trending NewsILMNIllumina4.7515 of 5 stars$91.87+0.2%$123.06+33.9%-27.8%$14.12B$4.37B11.639,030News CoveragePositive NewsAnalyst ForecastTECHBio-Techne4.7105 of 5 stars$52.23+0.7%$70.42+34.8%-15.8%$8.13B$1.22B113.553,100BIOBio-Rad Laboratories4.2623 of 5 stars$269.95-0.5%$333.50+23.5%-11.1%$7.30B$2.57B23.017,700CRLCharles River Laboratories International4.1688 of 5 stars$146.88-1.1%$177.07+20.6%-6.9%$7.23B$4.05B-110.4320,100News CoverageAnalyst Upgrade Related Companies and Tools Related Companies TXG Competitors HBIO Competitors TMO Competitors A Competitors MTD Competitors WAT Competitors ILMN Competitors TECH Competitors BIO Competitors CRL Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:PACB) was last updated on 10/5/2025 by MarketBeat.com Staff From Our PartnersMagnificent 7 being replaced by the “Hidden 7”?BULLISH: It's time to buy this 'hidden' AI stock An award-winning stock-rating system has turned BULLISH on...Chaikin Analytics | Sponsored$100 Trillion “AI Metal” Found in American Ghost TownJeff Brown recently traveled to a ghost town in the middle of an American desert… To investigate what could...Brownstone Research | SponsoredU.S. Government Sparking Crypto RallyU.S. Puts GDP on the Blockchain Could this spark the next crypto supercycle? 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