Prime Medicine (PRME) Competitors $3.72 +0.32 (+9.41%) As of 09/5/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisChartCompetitorsInsider TradesSEC FilingsTrendsBuy This Stock PRME vs. ATNFW, LBPSW, AEHAW, AIMDW, ALVOW, ARAV, ACABW, BFRIW, BTMDW, and BCTXWShould you be buying Prime Medicine stock or one of its competitors? The main competitors of Prime Medicine include 180 Life Sciences (ATNFW), 4D pharma (LBPSW), Aesther Healthcare Acquisition (AEHAW), Ainos (AIMDW), Alvotech (ALVOW), ARAVIVE (ARAV), Atlantic Coastal Acquisition Corp. II (ACABW), Biofrontera (BFRIW), biote (BTMDW), and BriaCell Therapeutics (BCTXW). These companies are all part of the "pharmaceutical products" industry. Prime Medicine vs. Its Competitors 180 Life Sciences 4D pharma Aesther Healthcare Acquisition Ainos Alvotech ARAVIVE Atlantic Coastal Acquisition Corp. II Biofrontera biote BriaCell Therapeutics 180 Life Sciences (NASDAQ:ATNFW) and Prime Medicine (NASDAQ:PRME) are both pharmaceutical products companies, but which is the superior business? We will contrast the two companies based on the strength of their risk, earnings, media sentiment, profitability, analyst recommendations, institutional ownership, valuation and dividends. Do institutionals & insiders hold more shares of ATNFW or PRME? 70.4% of Prime Medicine shares are owned by institutional investors. 22.7% of Prime Medicine shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth. Is ATNFW or PRME more profitable? 180 Life Sciences has a net margin of 0.00% compared to Prime Medicine's net margin of -4,016.83%. 180 Life Sciences' return on equity of 0.00% beat Prime Medicine's return on equity.Company Net Margins Return on Equity Return on Assets 180 Life SciencesN/A N/A N/A Prime Medicine -4,016.83%-156.16%-64.41% Which has preferable valuation & earnings, ATNFW or PRME? 180 Life Sciences has higher earnings, but lower revenue than Prime Medicine. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio180 Life SciencesN/AN/AN/AN/AN/APrime Medicine$2.98M167.99-$195.88M-$1.56-2.38 Does the media prefer ATNFW or PRME? In the previous week, Prime Medicine had 3 more articles in the media than 180 Life Sciences. MarketBeat recorded 3 mentions for Prime Medicine and 0 mentions for 180 Life Sciences. Prime Medicine's average media sentiment score of 0.20 beat 180 Life Sciences' score of 0.00 indicating that Prime Medicine is being referred to more favorably in the news media. Company Overall Sentiment 180 Life Sciences Neutral Prime Medicine Neutral SummaryPrime Medicine beats 180 Life Sciences on 5 of the 8 factors compared between the two stocks. Get Prime Medicine News Delivered to You Automatically Sign up to receive the latest news and ratings for PRME and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. Media Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart PRME vs. The Competition Export to ExcelMetricPrime MedicineBiological Products, Except Diagnostic Substances IndustryManufacturing SectorNASDAQ ExchangeMarket Cap$500.62M$238.22M$2.53B$9.92BDividend YieldN/AN/A2.53%4.51%P/E Ratio-2.38N/A26.3226.13Price / Sales167.99323.32110.60173.10Price / CashN/AN/A23.1859.28Price / Book3.182.2031.486.09Net Income-$195.88M-$111.70M$16.40M$266.51M7 Day PerformanceN/A-0.83%0.47%0.45%1 Month PerformanceN/A-18.45%2.75%5.05%1 Year PerformanceN/A115.86%31.90%26.03% Prime Medicine Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)PRMEPrime MedicineN/A$3.72+9.4%N/AN/A$500.62M$2.98M-2.38N/ANews CoverageAnalyst DowngradeATNFW180 Life SciencesN/A$0.21-10.6%N/A+2,715.6%$0.00N/A0.007Positive NewsGap DownLBPSW4D pharmaN/AN/AN/AN/A$0.00$522K0.00N/AAEHAWAesther Healthcare AcquisitionN/A$0.00flatN/AN/A$0.00N/A0.002AIMDWAinosN/A$0.23-2.5%N/AN/A$0.00$110.87K0.0040Positive NewsALVOWAlvotechN/A$1.07+2.9%N/A-54.9%$0.00$560.10M0.004Positive NewsGap UpHigh Trading VolumeARAVARAVIVEN/A$0.04flatN/AN/A$0.00$9.14M0.0020High Trading VolumeACABWAtlantic Coastal Acquisition Corp. IIN/A$0.05+29.9%N/A-31.1%$0.00N/A0.0015Gap UpBFRIWBiofronteraN/A$0.14-8.8%N/AN/A$0.00$39.19M0.0070Positive NewsBTMDWbioteN/A$0.01-15.6%N/A-96.5%$0.00$199.07M0.00N/AGap DownBCTXWBriaCell TherapeuticsN/A$0.03+1.7%N/A-87.5%$0.00N/A0.008News CoverageShort Interest ↓ Related Companies and Tools Related Companies 180 Life Sciences Competitors 4D pharma Competitors Aesther Healthcare Acquisition Competitors Ainos Competitors Alvotech Competitors ARAVIVE Competitors Atlantic Coastal Acquisition Corp. II Competitors Biofrontera Competitors biote Competitors BriaCell Therapeutics Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:PRME) was last updated on 9/7/2025 by MarketBeat.com Staff From Our PartnersWhy Trump’s “Smart Dollar” could rewrite the rulesMUST SEE: Donald Trump's Radical Overhaul of the U.S. Dollar Congress just approved President Trump's lates...Stansberry Research | SponsoredYour Bank Account Is No Longer SafeWhat If Washington Declared That: YOUR Money ISN'T Actually Yours? Sounds insane, but that's exactly what ...Priority Gold | SponsoredTrump's Law S.1582: $21T Dollar Revolution ComingDo you have money in any of these banks? Chase. Bank of America. Citigroup. Wells Fargo. U.S. Bancorp. 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