PureTech Health (PRTC) Competitors $17.31 +0.36 (+2.12%) Closing price 09/24/2025 03:50 PM EasternExtended Trading$17.65 +0.34 (+1.96%) As of 09/24/2025 05:08 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisChartCompetitorsFDA EventsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock PRTC vs. TWST, VERA, EWTX, AVDL, BHVN, HROW, JANX, COGT, SDGR, and SNDXShould you be buying PureTech Health stock or one of its competitors? The main competitors of PureTech Health include Twist Bioscience (TWST), Vera Therapeutics (VERA), Edgewise Therapeutics (EWTX), Avadel Pharmaceuticals (AVDL), Biohaven (BHVN), Harrow (HROW), Janux Therapeutics (JANX), Cogent Biosciences (COGT), Schrodinger (SDGR), and Syndax Pharmaceuticals (SNDX). These companies are all part of the "pharmaceutical products" industry. PureTech Health vs. Its Competitors Twist Bioscience Vera Therapeutics Edgewise Therapeutics Avadel Pharmaceuticals Biohaven Harrow Janux Therapeutics Cogent Biosciences Schrodinger Syndax Pharmaceuticals Twist Bioscience (NASDAQ:TWST) and PureTech Health (NASDAQ:PRTC) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their dividends, profitability, institutional ownership, earnings, media sentiment, valuation, risk and analyst recommendations. Does the media prefer TWST or PRTC? In the previous week, Twist Bioscience had 4 more articles in the media than PureTech Health. MarketBeat recorded 7 mentions for Twist Bioscience and 3 mentions for PureTech Health. PureTech Health's average media sentiment score of 1.47 beat Twist Bioscience's score of 0.62 indicating that PureTech Health is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Twist Bioscience 2 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive PureTech Health 1 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has higher earnings & valuation, TWST or PRTC? PureTech Health has lower revenue, but higher earnings than Twist Bioscience. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioTwist Bioscience$312.97M5.21-$208.73M-$1.45-18.63PureTech Health$4.83M86.62$27.78MN/AN/A Do institutionals & insiders have more ownership in TWST or PRTC? 0.0% of PureTech Health shares are held by institutional investors. 3.0% of Twist Bioscience shares are held by insiders. Comparatively, 5.3% of PureTech Health shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth. Do analysts prefer TWST or PRTC? Twist Bioscience currently has a consensus price target of $49.40, suggesting a potential upside of 82.83%. Given Twist Bioscience's stronger consensus rating and higher possible upside, research analysts clearly believe Twist Bioscience is more favorable than PureTech Health.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Twist Bioscience 1 Sell rating(s) 1 Hold rating(s) 9 Buy rating(s) 0 Strong Buy rating(s) 2.73PureTech Health 0 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 0.00 Is TWST or PRTC more profitable? PureTech Health has a net margin of 0.00% compared to Twist Bioscience's net margin of -23.51%. PureTech Health's return on equity of 0.00% beat Twist Bioscience's return on equity.Company Net Margins Return on Equity Return on Assets Twist Bioscience-23.51% -29.03% -21.77% PureTech Health N/A N/A N/A Which has more risk and volatility, TWST or PRTC? Twist Bioscience has a beta of 2.31, indicating that its share price is 131% more volatile than the S&P 500. Comparatively, PureTech Health has a beta of 1.11, indicating that its share price is 11% more volatile than the S&P 500. SummaryPureTech Health beats Twist Bioscience on 8 of the 14 factors compared between the two stocks. Get PureTech Health News Delivered to You Automatically Sign up to receive the latest news and ratings for PRTC and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding PRTC and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart PRTC vs. The Competition Export to ExcelMetricPureTech HealthMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$409.65M$3.15B$5.77B$10.42BDividend YieldN/A2.36%5.68%4.61%P/E RatioN/A20.7676.2826.42Price / Sales86.62444.26552.28127.65Price / Cash7.1145.9137.5661.52Price / Book1.029.8313.186.39Net Income$27.78M-$52.73M$3.29B$271.13M7 Day Performance15.52%1.84%0.84%0.93%1 Month Performance-9.56%7.48%5.03%7.52%1 Year Performance-13.62%19.92%71.27%30.06% PureTech Health Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)PRTCPureTech Health0.516 of 5 stars$17.31+2.1%N/A-11.1%$409.65M$4.83M0.00100TWSTTwist Bioscience3.8726 of 5 stars$25.72+1.6%$49.40+92.1%-41.8%$1.53B$362.27M-17.74990VERAVera Therapeutics2.5467 of 5 stars$24.24+2.0%$63.00+159.9%-44.0%$1.52BN/A-6.7740Positive NewsEWTXEdgewise Therapeutics2.3282 of 5 stars$13.70-3.8%$40.55+196.0%-36.0%$1.50BN/A-8.8460AVDLAvadel Pharmaceuticals2.642 of 5 stars$15.19-1.4%$20.86+37.3%+22.0%$1.50B$169.12M-506.3370BHVNBiohaven3.1834 of 5 stars$13.75-1.3%$55.62+304.5%-69.4%$1.47BN/A-1.80239HROWHarrow2.9857 of 5 stars$42.82+8.6%$64.67+51.0%+4.3%$1.46B$227.66M-171.28180Trending NewsAnalyst ForecastAnalyst RevisionHigh Trading VolumeJANXJanux Therapeutics2.4283 of 5 stars$23.56-2.0%$80.92+243.4%-53.0%$1.45B$10.59M-13.0930COGTCogent Biosciences2.6776 of 5 stars$12.41-2.0%$20.00+61.2%+21.1%$1.44BN/A-6.9780SDGRSchrodinger2.8375 of 5 stars$18.46-0.6%$27.83+50.8%+0.8%$1.37B$237.92M-7.44790SNDXSyndax Pharmaceuticals3.9365 of 5 stars$15.84+1.9%$39.22+147.6%-17.9%$1.34B$23.68M-4.07110 Related Companies and Tools Related Companies TWST Alternatives VERA Alternatives EWTX Alternatives AVDL Alternatives BHVN Alternatives HROW Alternatives JANX Alternatives COGT Alternatives SDGR Alternatives SNDX Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:PRTC) was last updated on 9/25/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredHe Called Nvidia at $1.10. 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