Siga Technologies (SIGA) Competitors $8.47 -0.01 (-0.12%) Closing price 10/21/2025 04:00 PM EasternExtended Trading$8.44 -0.03 (-0.40%) As of 05:27 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsDividendEarningsFinancialsHeadlinesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock SIGA vs. MESO, IBRX, ADPT, RXRX, IDYA, DNLI, BHC, TVTX, ETNB, and SRPTShould you be buying Siga Technologies stock or one of its competitors? The main competitors of Siga Technologies include Mesoblast (MESO), ImmunityBio (IBRX), Adaptive Biotechnologies (ADPT), Recursion Pharmaceuticals (RXRX), IDEAYA Biosciences (IDYA), Denali Therapeutics (DNLI), Bausch Health Cos (BHC), Travere Therapeutics (TVTX), 89BIO (ETNB), and Sarepta Therapeutics (SRPT). These companies are all part of the "pharmaceutical products" industry. Siga Technologies vs. Its Competitors Mesoblast ImmunityBio Adaptive Biotechnologies Recursion Pharmaceuticals IDEAYA Biosciences Denali Therapeutics Bausch Health Cos Travere Therapeutics 89BIO Sarepta Therapeutics Siga Technologies (NASDAQ:SIGA) and Mesoblast (NASDAQ:MESO) are both medical companies, but which is the better investment? We will contrast the two companies based on the strength of their earnings, valuation, profitability, media sentiment, institutional ownership, analyst recommendations, dividends and risk. Is SIGA or MESO more profitable? Siga Technologies has a net margin of 45.73% compared to Mesoblast's net margin of 0.00%. Siga Technologies' return on equity of 40.52% beat Mesoblast's return on equity.Company Net Margins Return on Equity Return on Assets Siga Technologies45.73% 40.52% 35.62% Mesoblast N/A N/A N/A Which has preferable valuation & earnings, SIGA or MESO? Siga Technologies has higher revenue and earnings than Mesoblast. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioSiga Technologies$138.72M4.37$59.21M$1.137.50Mesoblast$17.20M136.72-$102.14MN/AN/A Does the media refer more to SIGA or MESO? In the previous week, Mesoblast had 5 more articles in the media than Siga Technologies. MarketBeat recorded 7 mentions for Mesoblast and 2 mentions for Siga Technologies. Siga Technologies' average media sentiment score of 1.00 beat Mesoblast's score of 0.39 indicating that Siga Technologies is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Siga Technologies 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Mesoblast 1 Very Positive mention(s) 3 Positive mention(s) 3 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Do analysts recommend SIGA or MESO? Mesoblast has a consensus price target of $24.00, indicating a potential upside of 30.65%. Given Mesoblast's stronger consensus rating and higher probable upside, analysts plainly believe Mesoblast is more favorable than Siga Technologies.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Siga Technologies 0 Sell rating(s) 1 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 2.00Mesoblast 1 Sell rating(s) 1 Hold rating(s) 1 Buy rating(s) 2 Strong Buy rating(s) 2.80 Do institutionals & insiders believe in SIGA or MESO? 55.4% of Siga Technologies shares are owned by institutional investors. Comparatively, 1.4% of Mesoblast shares are owned by institutional investors. 2.0% of Siga Technologies shares are owned by company insiders. Comparatively, 18.8% of Mesoblast shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Which has more volatility & risk, SIGA or MESO? Siga Technologies has a beta of 0.96, indicating that its share price is 4% less volatile than the S&P 500. Comparatively, Mesoblast has a beta of 2.3, indicating that its share price is 130% more volatile than the S&P 500. SummaryMesoblast beats Siga Technologies on 8 of the 15 factors compared between the two stocks. Get Siga Technologies News Delivered to You Automatically Sign up to receive the latest news and ratings for SIGA and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SIGA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SIGA vs. The Competition Export to ExcelMetricSiga TechnologiesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$607.22M$3.01B$6.21B$10.68BDividend YieldN/A57.76%5.72%4.88%P/E Ratio7.5023.5929.1427.23Price / Sales4.37780.79587.91132.66Price / Cash10.13171.3937.5161.65Price / Book2.805.4112.526.59Net Income$59.21M$33.06M$3.32B$276.14M7 Day Performance0.59%-0.68%0.77%-0.72%1 Month Performance-9.61%8.13%7.29%2.47%1 Year Performance27.37%-2.15%64.58%33.90% Siga Technologies Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SIGASiga Technologies2.0213 of 5 stars$8.47-0.1%N/A+23.1%$607.22M$138.72M7.5040MESOMesoblast2.0166 of 5 stars$18.14-1.0%$24.00+32.3%+90.4%$2.34B$17.20M0.0080News CoverageGap UpIBRXImmunityBio2.8087 of 5 stars$2.48+5.1%$10.75+333.5%-31.3%$2.32B$14.74M-5.17590ADPTAdaptive Biotechnologies2.9706 of 5 stars$15.50+2.2%$13.56-12.5%+281.3%$2.31B$178.96M-18.90790RXRXRecursion Pharmaceuticals1.9301 of 5 stars$5.53+3.9%$7.25+31.1%-9.6%$2.31B$58.84M-3.11400IDYAIDEAYA Biosciences4.3241 of 5 stars$26.77+2.0%$43.36+62.0%-5.4%$2.30B$7M-7.0680Trending NewsAnalyst ForecastDNLIDenali Therapeutics4.2162 of 5 stars$14.98-2.5%$33.50+123.6%-35.7%$2.25B$330.53M-5.35430BHCBausch Health Cos4.6869 of 5 stars$6.15+1.6%$9.00+46.5%-24.9%$2.24B$9.63B23.6420,700Upcoming EarningsTVTXTravere Therapeutics2.973 of 5 stars$26.20+4.1%$35.21+34.4%+53.6%$2.24B$233.18M-12.84460ETNB89BIO3.1974 of 5 stars$14.80flat$25.81+74.4%+82.0%$2.19BN/A-4.1040Short Interest ↓SRPTSarepta Therapeutics4.6552 of 5 stars$21.96-0.7%$34.42+56.7%-81.7%$2.16B$1.90B-25.241,372Positive News Related Companies and Tools Related Companies Mesoblast Alternatives ImmunityBio Alternatives Adaptive Biotechnologies Alternatives Recursion Pharmaceuticals Alternatives IDEAYA Biosciences Alternatives Denali Therapeutics Alternatives Bausch Health Cos Alternatives Travere Therapeutics Alternatives 89BIO Alternatives Sarepta Therapeutics Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SIGA) was last updated on 10/22/2025 by MarketBeat.com Staff From Our PartnersIs Nvidia about to Trigger Another 150X Opportunity?Nvidia gave investors a chance to make more than 150 times their money with its AI chips, known as graphics pr...InvestorPlace | SponsoredNEW LAW: Congress Approves Setup For Digital Dollar?Trump Ally Says Congress Approved the Setup for a Digital Dollar 2.0 But according to Rep. 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