Sionna Therapeutics (SION) Competitors $20.87 +2.71 (+14.92%) As of 07/2/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock SION vs. AMRX, MIRM, IBRX, XENE, BHC, GMTX, APLS, TWST, ARWR, and RXRXShould you be buying Sionna Therapeutics stock or one of its competitors? The main competitors of Sionna Therapeutics include Amneal Pharmaceuticals (AMRX), Mirum Pharmaceuticals (MIRM), ImmunityBio (IBRX), Xenon Pharmaceuticals (XENE), Bausch Health Cos (BHC), Gemini Therapeutics (GMTX), Apellis Pharmaceuticals (APLS), Twist Bioscience (TWST), Arrowhead Pharmaceuticals (ARWR), and Recursion Pharmaceuticals (RXRX). These companies are all part of the "pharmaceutical products" industry. Sionna Therapeutics vs. Its Competitors Amneal Pharmaceuticals Mirum Pharmaceuticals ImmunityBio Xenon Pharmaceuticals Bausch Health Cos Gemini Therapeutics Apellis Pharmaceuticals Twist Bioscience Arrowhead Pharmaceuticals Recursion Pharmaceuticals Amneal Pharmaceuticals (NASDAQ:AMRX) and Sionna Therapeutics (NASDAQ:SION) are both medical companies, but which is the better stock? We will compare the two businesses based on the strength of their profitability, earnings, media sentiment, analyst recommendations, dividends, risk, institutional ownership and valuation. Which has stronger earnings & valuation, AMRX or SION? Sionna Therapeutics has lower revenue, but higher earnings than Amneal Pharmaceuticals. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAmneal Pharmaceuticals$2.79B0.94-$116.89M-$0.04-209.25Sionna TherapeuticsN/AN/A-$61.69MN/AN/A Does the media refer more to AMRX or SION? In the previous week, Amneal Pharmaceuticals had 1 more articles in the media than Sionna Therapeutics. MarketBeat recorded 7 mentions for Amneal Pharmaceuticals and 6 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 1.35 beat Amneal Pharmaceuticals' score of 0.71 indicating that Sionna Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Amneal Pharmaceuticals 2 Very Positive mention(s) 1 Positive mention(s) 4 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Sionna Therapeutics 3 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do analysts recommend AMRX or SION? Amneal Pharmaceuticals currently has a consensus target price of $11.60, suggesting a potential upside of 38.59%. Sionna Therapeutics has a consensus target price of $38.50, suggesting a potential upside of 84.48%. Given Sionna Therapeutics' higher possible upside, analysts plainly believe Sionna Therapeutics is more favorable than Amneal Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Amneal Pharmaceuticals 0 Sell rating(s) 0 Hold rating(s) 5 Buy rating(s) 0 Strong Buy rating(s) 3.00Sionna Therapeutics 0 Sell rating(s) 0 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 3.00 Do institutionals and insiders hold more shares of AMRX or SION? 31.8% of Amneal Pharmaceuticals shares are held by institutional investors. 26.6% of Amneal Pharmaceuticals shares are held by company insiders. Comparatively, 3.9% of Sionna Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Is AMRX or SION more profitable? Sionna Therapeutics has a net margin of 0.00% compared to Amneal Pharmaceuticals' net margin of -0.46%. Sionna Therapeutics' return on equity of 0.00% beat Amneal Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Amneal Pharmaceuticals-0.46% -188.26% 5.34% Sionna Therapeutics N/A N/A N/A SummaryAmneal Pharmaceuticals beats Sionna Therapeutics on 6 of the 11 factors compared between the two stocks. Get Sionna Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for SION and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SION and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SION vs. The Competition Export to ExcelMetricSionna TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$801.30M$2.88B$5.54B$8.87BDividend YieldN/A2.64%5.39%4.10%P/E RatioN/A21.3126.1919.90Price / SalesN/A278.47414.04113.66Price / CashN/A41.4736.1356.90Price / BookN/A7.518.025.38Net Income-$61.69M-$55.05M$3.15B$248.50M7 Day Performance40.73%2.07%1.48%2.06%1 Month Performance44.13%4.84%3.67%4.86%1 Year PerformanceN/A5.37%34.68%20.24% Sionna Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SIONSionna TherapeuticsN/A$20.87+14.9%$38.50+84.5%N/A$801.30MN/A0.0035News CoveragePositive NewsInsider TradeGap UpAMRXAmneal Pharmaceuticals3.3512 of 5 stars$8.12+0.8%$11.60+42.9%+28.0%$2.53B$2.79B-202.078,100MIRMMirum Pharmaceuticals3.4615 of 5 stars$50.40+0.5%$65.50+30.0%+45.8%$2.49B$336.89M-31.26140Positive NewsIBRXImmunityBio2.0572 of 5 stars$2.79+0.9%$12.25+339.9%-57.3%$2.46B$14.74M-4.80590XENEXenon Pharmaceuticals3.1684 of 5 stars$31.56-0.6%$54.82+73.7%-8.7%$2.42B$9.43M-9.77210BHCBausch Health Cos3.2418 of 5 stars$6.43+0.7%$7.42+15.4%+0.0%$2.38B$9.63B-58.4120,700GMTXGemini TherapeuticsN/A$53.92-2.0%N/A+10.0%$2.34BN/A-53.9230APLSApellis Pharmaceuticals4.5337 of 5 stars$18.33-0.3%$40.05+118.5%-49.1%$2.30B$781.37M-10.23770Trending NewsAnalyst ForecastAnalyst RevisionTWSTTwist Bioscience4.4187 of 5 stars$36.64-1.0%$50.40+37.6%-20.4%$2.20B$312.97M-11.28990News CoveragePositive NewsARWRArrowhead Pharmaceuticals3.9328 of 5 stars$15.60-0.4%$43.71+180.3%-33.0%$2.15B$3.55M-11.13400Positive NewsRXRXRecursion Pharmaceuticals1.8974 of 5 stars$5.29+2.4%$7.00+32.5%-27.2%$2.15B$58.84M-2.99400 Related Companies and Tools Related Companies AMRX Alternatives MIRM Alternatives IBRX Alternatives XENE Alternatives BHC Alternatives GMTX Alternatives APLS Alternatives TWST Alternatives ARWR Alternatives RXRX Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SION) was last updated on 7/3/2025 by MarketBeat.com Staff From Our PartnersTrump’s New Order Could Boost Social Security Benefits by 400%If you collect—or plan to collect—Social Security, you need to see this. 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