Sionna Therapeutics (SION) Competitors $24.00 +0.94 (+4.08%) As of 09/5/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock SION vs. ADMA, ACLX, ARWR, MLTX, MTSR, MIRM, PTGX, LNTH, APLS, and AAPGShould you be buying Sionna Therapeutics stock or one of its competitors? The main competitors of Sionna Therapeutics include ADMA Biologics (ADMA), Arcellx (ACLX), Arrowhead Pharmaceuticals (ARWR), MoonLake Immunotherapeutics (MLTX), Metsera (MTSR), Mirum Pharmaceuticals (MIRM), Protagonist Therapeutics (PTGX), Lantheus (LNTH), Apellis Pharmaceuticals (APLS), and Ascentage Pharma Group International (AAPG). These companies are all part of the "pharmaceutical products" industry. Sionna Therapeutics vs. Its Competitors ADMA Biologics Arcellx Arrowhead Pharmaceuticals MoonLake Immunotherapeutics Metsera Mirum Pharmaceuticals Protagonist Therapeutics Lantheus Apellis Pharmaceuticals Ascentage Pharma Group International ADMA Biologics (NASDAQ:ADMA) and Sionna Therapeutics (NASDAQ:SION) are both medical companies, but which is the better investment? We will compare the two companies based on the strength of their risk, dividends, analyst recommendations, institutional ownership, media sentiment, valuation, earnings and profitability. Which has preferable earnings & valuation, ADMA or SION? ADMA Biologics has higher revenue and earnings than Sionna Therapeutics. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioADMA Biologics$474.17M8.49$197.67M$0.8619.62Sionna TherapeuticsN/AN/A-$61.69MN/AN/A Do insiders and institutionals have more ownership in ADMA or SION? 75.7% of ADMA Biologics shares are held by institutional investors. 3.5% of ADMA Biologics shares are held by company insiders. Comparatively, 3.9% of Sionna Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term. Does the media favor ADMA or SION? In the previous week, Sionna Therapeutics had 10 more articles in the media than ADMA Biologics. MarketBeat recorded 20 mentions for Sionna Therapeutics and 10 mentions for ADMA Biologics. ADMA Biologics' average media sentiment score of 1.75 beat Sionna Therapeutics' score of 0.87 indicating that ADMA Biologics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment ADMA Biologics 10 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Sionna Therapeutics 12 Very Positive mention(s) 1 Positive mention(s) 4 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is ADMA or SION more profitable? ADMA Biologics has a net margin of 44.06% compared to Sionna Therapeutics' net margin of 0.00%. ADMA Biologics' return on equity of 41.01% beat Sionna Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets ADMA Biologics44.06% 41.01% 28.47% Sionna Therapeutics N/A N/A N/A Do analysts prefer ADMA or SION? ADMA Biologics currently has a consensus price target of $27.67, indicating a potential upside of 64.00%. Sionna Therapeutics has a consensus price target of $36.00, indicating a potential upside of 50.00%. Given ADMA Biologics' stronger consensus rating and higher possible upside, equities research analysts plainly believe ADMA Biologics is more favorable than Sionna Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score ADMA Biologics 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 1 Strong Buy rating(s) 3.33Sionna Therapeutics 0 Sell rating(s) 1 Hold rating(s) 3 Buy rating(s) 1 Strong Buy rating(s) 3.00 SummaryADMA Biologics beats Sionna Therapeutics on 9 of the 12 factors compared between the two stocks. Get Sionna Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for SION and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SION and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SION vs. The Competition Export to ExcelMetricSionna TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.02B$3.13B$5.80B$9.91BDividend YieldN/A2.28%6.71%4.52%P/E RatioN/A20.9775.7426.11Price / SalesN/A290.81479.0187.70Price / CashN/A44.9736.9659.04Price / BookN/A9.8711.456.09Net Income-$61.69M-$53.42M$3.29B$266.42M7 Day Performance-2.52%2.93%1.01%0.45%1 Month Performance41.34%9.85%7.89%4.57%1 Year PerformanceN/A15.74%62.80%26.11% Sionna Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SIONSionna TherapeuticsN/A$24.00+4.1%$36.00+50.0%N/A$1.02BN/A0.0035News CoverageAnalyst ForecastInsider TradeADMAADMA Biologics3.7607 of 5 stars$16.91+0.1%$27.67+63.6%+0.8%$4.04B$426.45M19.66530Positive NewsACLXArcellx2.6379 of 5 stars$72.16+1.3%$114.31+58.4%+3.2%$4.00B$107.94M-21.1080News CoveragePositive NewsARWRArrowhead Pharmaceuticals3.9506 of 5 stars$28.00+0.7%$43.14+54.1%+25.1%$3.87B$3.55M-21.88400Trending NewsAnalyst ForecastInsider TradeAnalyst RevisionMLTXMoonLake Immunotherapeutics2.6091 of 5 stars$59.72+0.4%$74.43+24.6%+30.4%$3.84BN/A-21.482News CoverageAnalyst RevisionMTSRMetseraN/A$36.29+1.8%$59.00+62.6%N/A$3.81BN/A0.0081News CoveragePositive NewsAnalyst ForecastMIRMMirum Pharmaceuticals3.0674 of 5 stars$74.18-0.6%$74.13-0.1%+82.6%$3.73B$429.16M-61.31140Positive NewsPTGXProtagonist Therapeutics1.8406 of 5 stars$59.60+2.6%$67.20+12.8%+44.1%$3.71B$434.43M85.14120News CoveragePositive NewsLNTHLantheus4.802 of 5 stars$53.82-2.4%$91.60+70.2%-48.0%$3.66B$1.53B14.31700Positive NewsShort Interest ↓APLSApellis Pharmaceuticals4.479 of 5 stars$28.65+3.1%$34.12+19.1%-28.4%$3.62B$781.37M-15.74770News CoveragePositive NewsAAPGAscentage Pharma Group InternationalN/A$38.58-6.6%N/AN/A$3.59B$390.60M0.00600Positive NewsGap Up Related Companies and Tools Related Companies ADMA Alternatives ACLX Alternatives ARWR Alternatives MLTX Alternatives MTSR Alternatives MIRM Alternatives PTGX Alternatives LNTH Alternatives APLS Alternatives AAPG Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SION) was last updated on 9/6/2025 by MarketBeat.com Staff From Our PartnersCapital Gains Tax Strategies for SeniorsCapital gains taxes can take a bite out of your retirement income—unless you have a smart strategy. 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