Sionna Therapeutics (SION) Competitors $30.01 +0.71 (+2.42%) As of 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock SION vs. PTCT, KRYS, ARWR, ACLX, MENS, PCVX, PTGX, AKRO, KYMR, and ADMAShould you be buying Sionna Therapeutics stock or one of its competitors? The main competitors of Sionna Therapeutics include PTC Therapeutics (PTCT), Krystal Biotech (KRYS), Arrowhead Pharmaceuticals (ARWR), Arcellx (ACLX), Jyong Biotech (MENS), Vaxcyte (PCVX), Protagonist Therapeutics (PTGX), Akero Therapeutics (AKRO), Kymera Therapeutics (KYMR), and ADMA Biologics (ADMA). These companies are all part of the "pharmaceutical products" industry. Sionna Therapeutics vs. Its Competitors PTC Therapeutics Krystal Biotech Arrowhead Pharmaceuticals Arcellx Jyong Biotech Vaxcyte Protagonist Therapeutics Akero Therapeutics Kymera Therapeutics ADMA Biologics Sionna Therapeutics (NASDAQ:SION) and PTC Therapeutics (NASDAQ:PTCT) are both medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their profitability, risk, institutional ownership, valuation, media sentiment, earnings, analyst recommendations and dividends. Does the media favor SION or PTCT? In the previous week, Sionna Therapeutics had 14 more articles in the media than PTC Therapeutics. MarketBeat recorded 18 mentions for Sionna Therapeutics and 4 mentions for PTC Therapeutics. PTC Therapeutics' average media sentiment score of 0.40 beat Sionna Therapeutics' score of 0.33 indicating that PTC Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Sionna Therapeutics 8 Very Positive mention(s) 3 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral PTC Therapeutics 1 Very Positive mention(s) 1 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Do analysts recommend SION or PTCT? Sionna Therapeutics currently has a consensus price target of $38.00, indicating a potential upside of 26.62%. PTC Therapeutics has a consensus price target of $69.00, indicating a potential upside of 5.55%. Given Sionna Therapeutics' stronger consensus rating and higher probable upside, equities analysts plainly believe Sionna Therapeutics is more favorable than PTC Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Sionna Therapeutics 1 Sell rating(s) 1 Hold rating(s) 4 Buy rating(s) 1 Strong Buy rating(s) 2.71PTC Therapeutics 1 Sell rating(s) 6 Hold rating(s) 9 Buy rating(s) 0 Strong Buy rating(s) 2.50 Which has stronger earnings and valuation, SION or PTCT? Sionna Therapeutics has higher earnings, but lower revenue than PTC Therapeutics. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioSionna TherapeuticsN/AN/A-$61.69MN/AN/APTC Therapeutics$1.76B2.94-$363.30M$6.979.38 Is SION or PTCT more profitable? PTC Therapeutics has a net margin of 35.65% compared to Sionna Therapeutics' net margin of 0.00%. Sionna Therapeutics' return on equity of 0.00% beat PTC Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Sionna TherapeuticsN/A N/A N/A PTC Therapeutics 35.65%-106.31%30.61% SummarySionna Therapeutics beats PTC Therapeutics on 6 of the 11 factors compared between the two stocks. Get Sionna Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for SION and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SION and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SION vs. The Competition Export to ExcelMetricSionna TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.29B$3.31B$6.05B$10.58BDividend YieldN/A2.28%5.68%4.69%P/E RatioN/A21.7377.3326.67Price / SalesN/A442.93598.94129.44Price / CashN/A46.6137.7361.25Price / BookN/A9.9312.556.55Net Income-$61.69M-$52.59M$3.30B$277.26M7 Day Performance3.70%5.28%28,056.17%2.41%1 Month Performance22.24%12.54%28,977.34%9.26%1 Year PerformanceN/A28.76%35,796.37%32.66% Sionna Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SIONSionna Therapeutics2.9439 of 5 stars$30.01+2.4%$38.00+26.6%N/A$1.29BN/A0.0035Insider TradePTCTPTC Therapeutics3.4131 of 5 stars$57.84-2.8%$69.00+19.3%+73.0%$4.73B$806.78M7.851,410KRYSKrystal Biotech4.6775 of 5 stars$161.15-0.5%$209.00+29.7%+2.4%$4.69B$290.52M32.93210Positive NewsARWRArrowhead Pharmaceuticals4.202 of 5 stars$31.66-3.6%$43.14+36.3%+80.0%$4.54B$3.55M0.00400Positive NewsInsider TradeACLXArcellx2.3654 of 5 stars$78.40-0.4%$114.31+45.8%+7.9%$4.37B$107.94M0.0080Insider TradeMENSJyong BiotechN/A$59.25+4.9%N/AN/A$4.30BN/A0.0031PCVXVaxcyte2.4644 of 5 stars$32.14-2.1%$106.25+230.6%-64.9%$4.26BN/A0.00160Positive NewsPTGXProtagonist Therapeutics2.1533 of 5 stars$64.70-1.9%$68.36+5.7%+44.5%$4.10B$434.43M94.21120Positive NewsAKROAkero Therapeutics3.8275 of 5 stars$46.22-2.6%$81.14+75.6%+58.9%$3.80BN/A0.0030Positive NewsInsider TradeKYMRKymera Therapeutics1.9245 of 5 stars$53.74+2.4%$59.95+11.6%+24.4%$3.75B$47.07M0.00170Analyst ForecastADMAADMA Biologics3.7407 of 5 stars$15.32-2.2%$27.67+80.6%-25.5%$3.74B$426.45M27.00530 Related Companies and Tools Related Companies PTCT Alternatives KRYS Alternatives ARWR Alternatives ACLX Alternatives MENS Alternatives PCVX Alternatives PTGX Alternatives AKRO Alternatives KYMR Alternatives ADMA Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SION) was last updated on 10/3/2025 by MarketBeat.com Staff From Our PartnersMagnificent 7 being replaced by the “Hidden 7”?BULLISH: It's time to buy this 'hidden' AI stock An award-winning stock-rating system has turned BULLISH on...Chaikin Analytics | SponsoredU.S. Government Sparking Crypto RallyU.S. Puts GDP on the Blockchain Could this spark the next crypto supercycle? 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