Taysha Gene Therapies (TSHA) Competitors $5.34 +0.18 (+3.49%) Closing price 04:00 PM EasternExtended Trading$5.35 +0.01 (+0.19%) As of 06:28 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock TSHA vs. HHH, PTCT, ARWR, ACLX, KYMR, PTGX, CRNX, ZLAB, AKRO, and ACADShould you be buying Taysha Gene Therapies stock or one of its competitors? The main competitors of Taysha Gene Therapies include Howard Hughes (HHH), PTC Therapeutics (PTCT), Arrowhead Pharmaceuticals (ARWR), Arcellx (ACLX), Kymera Therapeutics (KYMR), Protagonist Therapeutics (PTGX), Crinetics Pharmaceuticals (CRNX), Zai Lab (ZLAB), Akero Therapeutics (AKRO), and ACADIA Pharmaceuticals (ACAD). Taysha Gene Therapies vs. Its Competitors Howard Hughes PTC Therapeutics Arrowhead Pharmaceuticals Arcellx Kymera Therapeutics Protagonist Therapeutics Crinetics Pharmaceuticals Zai Lab Akero Therapeutics ACADIA Pharmaceuticals Taysha Gene Therapies (NASDAQ:TSHA) and Howard Hughes (NYSE:HHH) are related companies, but which is the superior business? We will compare the two companies based on the strength of their dividends, analyst recommendations, earnings, risk, profitability, media sentiment, valuation and institutional ownership. Is TSHA or HHH more profitable? Howard Hughes has a net margin of 12.85% compared to Taysha Gene Therapies' net margin of -1,144.97%. Howard Hughes' return on equity of 10.51% beat Taysha Gene Therapies' return on equity.Company Net Margins Return on Equity Return on Assets Taysha Gene Therapies-1,144.97% -78.44% -44.82% Howard Hughes 12.85%10.51%3.15% Which has more volatility and risk, TSHA or HHH? Taysha Gene Therapies has a beta of 0.99, suggesting that its stock price is 1% less volatile than the S&P 500. Comparatively, Howard Hughes has a beta of 1.23, suggesting that its stock price is 23% more volatile than the S&P 500. Do institutionals & insiders hold more shares of TSHA or HHH? 77.7% of Taysha Gene Therapies shares are owned by institutional investors. Comparatively, 93.8% of Howard Hughes shares are owned by institutional investors. 3.8% of Taysha Gene Therapies shares are owned by insiders. Comparatively, 48.0% of Howard Hughes shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth. Which has higher valuation & earnings, TSHA or HHH? Howard Hughes has higher revenue and earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than Howard Hughes, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioTaysha Gene Therapies$8.33M174.88-$89.30M-$0.34-15.71Howard Hughes$1.75B2.75$200.55M$4.5717.75 Do analysts rate TSHA or HHH? Taysha Gene Therapies presently has a consensus target price of $9.00, suggesting a potential upside of 68.54%. Howard Hughes has a consensus target price of $83.33, suggesting a potential upside of 2.76%. Given Taysha Gene Therapies' higher probable upside, research analysts clearly believe Taysha Gene Therapies is more favorable than Howard Hughes.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Taysha Gene Therapies 1 Sell rating(s) 0 Hold rating(s) 9 Buy rating(s) 0 Strong Buy rating(s) 2.80Howard Hughes 0 Sell rating(s) 2 Hold rating(s) 2 Buy rating(s) 1 Strong Buy rating(s) 2.80 Does the media prefer TSHA or HHH? In the previous week, Taysha Gene Therapies had 3 more articles in the media than Howard Hughes. MarketBeat recorded 8 mentions for Taysha Gene Therapies and 5 mentions for Howard Hughes. Howard Hughes' average media sentiment score of 0.86 beat Taysha Gene Therapies' score of 0.36 indicating that Howard Hughes is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Taysha Gene Therapies 0 Very Positive mention(s) 1 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Howard Hughes 3 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive SummaryHoward Hughes beats Taysha Gene Therapies on 12 of the 16 factors compared between the two stocks. Get Taysha Gene Therapies News Delivered to You Automatically Sign up to receive the latest news and ratings for TSHA and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding TSHA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart TSHA vs. The Competition Export to ExcelMetricTaysha Gene TherapiesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.46B$4.49B$6.05B$10.51BDividend YieldN/A0.87%5.73%4.80%P/E Ratio-15.7110.6785.4427.36Price / Sales174.8823.39516.11196.40Price / CashN/A7.0837.5761.53Price / Book15.264.4412.426.82Net Income-$89.30M-$134.23M$3.32B$276.89M7 Day Performance5.53%1.24%1.01%0.27%1 Month Performance76.82%17.66%10.75%8.31%1 Year Performance173.85%71.72%76.19%35.60% Taysha Gene Therapies Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)TSHATaysha Gene Therapies2.3988 of 5 stars$5.34+3.5%$9.00+68.5%+159.3%$1.46B$8.33M-15.71180Gap UpHHHHoward Hughes2.232 of 5 stars$85.10+0.4%$83.33-2.1%+3.4%$5.03B$1.75B18.62608PTCTPTC Therapeutics3.2259 of 5 stars$64.80-0.9%$69.00+6.5%+68.9%$5.19B$1.76B9.301,410Analyst RevisionARWRArrowhead Pharmaceuticals3.8861 of 5 stars$37.50+3.8%$43.14+15.0%+85.7%$4.99B$3.55M-29.30400ACLXArcellx2.0028 of 5 stars$84.38-0.8%$114.31+35.5%+0.6%$4.72B$107.94M-24.6780Analyst RevisionKYMRKymera Therapeutics1.344 of 5 stars$57.55-0.6%$61.26+6.5%+26.5%$4.14B$47.07M-16.58170Insider TradePTGXProtagonist Therapeutics1.6812 of 5 stars$64.14-1.1%$68.36+6.6%+66.0%$4.03B$434.43M91.63120Positive NewsAnalyst ForecastInsider TradeCRNXCrinetics Pharmaceuticals3.7504 of 5 stars$41.68+2.0%$74.45+78.6%-17.0%$3.85B$1.04M-10.14210ZLABZai Lab2.7796 of 5 stars$33.31-1.3%$56.35+69.2%+18.9%$3.77B$398.99M-16.331,869News CoveragePositive NewsAKROAkero Therapeutics3.6892 of 5 stars$46.04-0.1%$81.14+76.2%+79.3%$3.69BN/A-23.0230Insider TradeACADACADIA Pharmaceuticals4.5081 of 5 stars$21.59-1.0%$29.12+34.9%+35.8%$3.68B$1.02B16.23510Analyst Forecast Related Companies and Tools Related Companies HHH Alternatives PTCT Alternatives ARWR Alternatives ACLX Alternatives KYMR Alternatives PTGX Alternatives CRNX Alternatives ZLAB Alternatives AKRO Alternatives ACAD Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:TSHA) was last updated on 10/15/2025 by MarketBeat.com Staff From Our PartnersURGENT: The Market's 3 Red Flags Are FlashingHere’s the uncomfortable truth: The smartest investors in the world are already preparing for a crash befor...StockEarnings | SponsoredINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredCapital Gains Tax Strategies for SeniorsCapital gains taxes can take a bite out of your retirement income—unless you have a smart strategy. 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