Vanda Pharmaceuticals (VNDA) Competitors $4.38 -0.13 (-2.88%) Closing price 04:00 PM EasternExtended Trading$4.43 +0.05 (+1.14%) As of 05:47 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock VNDA vs. OPK, GERN, ZBIO, RIGL, VSTM, MYGN, XOMA, EBS, LXRX, and CBIOShould you be buying Vanda Pharmaceuticals stock or one of its competitors? The main competitors of Vanda Pharmaceuticals include OPKO Health (OPK), Geron (GERN), Zenas BioPharma (ZBIO), Rigel Pharmaceuticals (RIGL), Verastem (VSTM), Myriad Genetics (MYGN), XOMA Royalty (XOMA), Emergent Biosolutions (EBS), Lexicon Pharmaceuticals (LXRX), and Crescent Biopharma (CBIO). These companies are all part of the "biotechnology" industry. Vanda Pharmaceuticals vs. Its Competitors OPKO Health Geron Zenas BioPharma Rigel Pharmaceuticals Verastem Myriad Genetics XOMA Royalty Emergent Biosolutions Lexicon Pharmaceuticals Crescent Biopharma Vanda Pharmaceuticals (NASDAQ:VNDA) and OPKO Health (NASDAQ:OPK) are both small-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their risk, analyst recommendations, valuation, profitability, dividends, institutional ownership, media sentiment and earnings. Do institutionals and insiders have more ownership in VNDA or OPK? 88.1% of Vanda Pharmaceuticals shares are held by institutional investors. Comparatively, 64.6% of OPKO Health shares are held by institutional investors. 8.9% of Vanda Pharmaceuticals shares are held by insiders. Comparatively, 49.7% of OPKO Health shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term. Is VNDA or OPK more profitable? OPKO Health has a net margin of -26.68% compared to Vanda Pharmaceuticals' net margin of -32.90%. Vanda Pharmaceuticals' return on equity of -12.89% beat OPKO Health's return on equity.Company Net Margins Return on Equity Return on Assets Vanda Pharmaceuticals-32.90% -12.89% -10.47% OPKO Health -26.68%-13.17%-8.28% Which has more volatility & risk, VNDA or OPK? Vanda Pharmaceuticals has a beta of 0.74, suggesting that its share price is 26% less volatile than the S&P 500. Comparatively, OPKO Health has a beta of 1.4, suggesting that its share price is 40% more volatile than the S&P 500. Do analysts prefer VNDA or OPK? Vanda Pharmaceuticals currently has a consensus target price of $16.50, indicating a potential upside of 276.71%. OPKO Health has a consensus target price of $2.75, indicating a potential upside of 99.28%. Given Vanda Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts plainly believe Vanda Pharmaceuticals is more favorable than OPKO Health.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Vanda Pharmaceuticals 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 1 Strong Buy rating(s) 3.50OPKO Health 0 Sell rating(s) 2 Hold rating(s) 3 Buy rating(s) 1 Strong Buy rating(s) 2.83 Which has preferable valuation and earnings, VNDA or OPK? Vanda Pharmaceuticals has higher earnings, but lower revenue than OPKO Health. OPKO Health is trading at a lower price-to-earnings ratio than Vanda Pharmaceuticals, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioVanda Pharmaceuticals$198.77M1.30-$18.90M-$1.13-3.88OPKO Health$713.10M1.54-$53.22M-$0.25-5.52 Does the media favor VNDA or OPK? In the previous week, OPKO Health had 2 more articles in the media than Vanda Pharmaceuticals. MarketBeat recorded 4 mentions for OPKO Health and 2 mentions for Vanda Pharmaceuticals. Vanda Pharmaceuticals' average media sentiment score of 1.68 beat OPKO Health's score of 0.97 indicating that Vanda Pharmaceuticals is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Vanda Pharmaceuticals 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive OPKO Health 1 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive SummaryOPKO Health beats Vanda Pharmaceuticals on 9 of the 16 factors compared between the two stocks. Get Vanda Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for VNDA and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding VNDA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart VNDA vs. The Competition Export to ExcelMetricVanda PharmaceuticalsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$266.49M$3.11B$5.75B$10.24BDividend YieldN/A2.32%5.69%4.60%P/E Ratio-3.8821.3874.9326.41Price / Sales1.30224.82452.3586.56Price / CashN/A44.4425.8129.91Price / Book0.479.6413.256.28Net Income-$18.90M-$53.20M$3.29B$270.38M7 Day Performance-3.74%0.44%0.47%2.70%1 Month Performance0.46%4.26%4.60%5.99%1 Year Performance-14.12%9.43%73.42%25.94% Vanda Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)VNDAVanda Pharmaceuticals4.0647 of 5 stars$4.38-2.9%$16.50+276.7%-11.6%$266.49M$198.77M-3.88290OPKOPKO Health4.3979 of 5 stars$1.42+5.2%$2.75+93.7%-10.8%$1.07B$713.10M-5.682,997News CoverageGERNGeron3.1347 of 5 stars$1.37-2.1%$4.19+205.7%-71.8%$893.22M$164.45M-10.5470Positive NewsZBIOZenas BioPharma1.05 of 5 stars$21.51+4.9%$36.67+70.5%N/A$863.68M$5M-6.06N/AHigh Trading VolumeRIGLRigel Pharmaceuticals2.0337 of 5 stars$40.87-1.1%$38.20-6.5%+177.1%$741.53M$179.28M7.55160Positive NewsVSTMVerastem2.8729 of 5 stars$10.23-5.0%$13.29+29.9%+245.9%$662.84M$2.14M-3.1250Positive NewsAnalyst DowngradeMYGNMyriad Genetics3.7145 of 5 stars$6.91+4.5%$12.45+80.2%-73.8%$615.03M$832.90M-1.612,700Positive NewsXOMAXOMA Royalty4.2122 of 5 stars$35.35+0.3%$69.50+96.6%+29.1%$425.97M$28.49M-22.8110Positive NewsEBSEmergent Biosolutions4.7438 of 5 stars$7.59+0.1%$14.33+88.9%+3.6%$404.40M$812.50M3.102,420Positive NewsLXRXLexicon Pharmaceuticals2.3631 of 5 stars$1.08-0.9%$3.23+198.6%-32.4%$396.11M$31.08M-3.27140CBIOCrescent Biopharma4.3785 of 5 stars$12.95-9.1%$25.60+97.7%N/A$278.39M$10K-0.3750Gap Down Related Companies and Tools Related Companies OPKO Health Competitors Geron Competitors Zenas BioPharma Competitors Rigel Pharmaceuticals Competitors Verastem Competitors Myriad Genetics Competitors XOMA Royalty Competitors Emergent Biosolutions Competitors Lexicon Pharmaceuticals Competitors Crescent Biopharma Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:VNDA) was last updated on 9/15/2025 by MarketBeat.com Staff From Our PartnersHe Called Nvidia at $1.10. 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