Xenetic Biosciences (XBIO) Competitors $2.89 +0.07 (+2.34%) Closing price 08/22/2025 03:19 PM EasternExtended Trading$2.91 +0.02 (+0.83%) As of 08/22/2025 06:55 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsOwnershipSEC FilingsShort InterestTrendsBuy This Stock XBIO vs. SYBX, LSB, HOTH, IMNN, MTEX, LEXX, LPCN, CLDI, BLRX, and NRSNShould you be buying Xenetic Biosciences stock or one of its competitors? The main competitors of Xenetic Biosciences include Synlogic (SYBX), LakeShore Biopharma (LSB), Hoth Therapeutics (HOTH), Imunon (IMNN), Mannatech (MTEX), Lexaria Bioscience (LEXX), Lipocine (LPCN), Calidi Biotherapeutics (CLDI), BioLineRx (BLRX), and NeuroSense Therapeutics (NRSN). These companies are all part of the "pharmaceutical products" industry. Xenetic Biosciences vs. Its Competitors Synlogic LakeShore Biopharma Hoth Therapeutics Imunon Mannatech Lexaria Bioscience Lipocine Calidi Biotherapeutics BioLineRx NeuroSense Therapeutics Synlogic (NASDAQ:SYBX) and Xenetic Biosciences (NASDAQ:XBIO) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, dividends, valuation, media sentiment, earnings, risk, analyst recommendations and profitability. Which has preferable valuation and earnings, SYBX or XBIO? Xenetic Biosciences has higher revenue and earnings than Synlogic. Xenetic Biosciences is trading at a lower price-to-earnings ratio than Synlogic, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioSynlogic$10K1,708.20-$23.36M-$2.51-0.58Xenetic Biosciences$2.50M1.78-$3.96M-$2.00-1.44 Do analysts rate SYBX or XBIO? Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Synlogic 0 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 0.00Xenetic Biosciences 0 Sell rating(s) 1 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 2.00 Is SYBX or XBIO more profitable? Synlogic has a net margin of 0.00% compared to Xenetic Biosciences' net margin of -126.08%. Synlogic's return on equity of -8.09% beat Xenetic Biosciences' return on equity.Company Net Margins Return on Equity Return on Assets SynlogicN/A -8.09% -5.50% Xenetic Biosciences -126.08%-54.56%-47.28% Do insiders & institutionals hold more shares of SYBX or XBIO? 63.4% of Synlogic shares are owned by institutional investors. Comparatively, 15.1% of Xenetic Biosciences shares are owned by institutional investors. 3.0% of Synlogic shares are owned by company insiders. Comparatively, 14.7% of Xenetic Biosciences shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term. Does the media favor SYBX or XBIO? In the previous week, Xenetic Biosciences had 3 more articles in the media than Synlogic. MarketBeat recorded 3 mentions for Xenetic Biosciences and 0 mentions for Synlogic. Xenetic Biosciences' average media sentiment score of 1.03 beat Synlogic's score of 0.00 indicating that Xenetic Biosciences is being referred to more favorably in the news media. Company Overall Sentiment Synlogic Neutral Xenetic Biosciences Positive Which has more volatility & risk, SYBX or XBIO? Synlogic has a beta of 0.52, meaning that its stock price is 48% less volatile than the S&P 500. Comparatively, Xenetic Biosciences has a beta of 2.31, meaning that its stock price is 131% more volatile than the S&P 500. SummaryXenetic Biosciences beats Synlogic on 8 of the 14 factors compared between the two stocks. Get Xenetic Biosciences News Delivered to You Automatically Sign up to receive the latest news and ratings for XBIO and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding XBIO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart XBIO vs. The Competition Export to ExcelMetricXenetic BiosciencesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$4.35M$2.56B$5.76B$9.61BDividend YieldN/A1.67%4.41%4.10%P/E Ratio-1.4422.6131.1026.04Price / Sales1.78544.11435.05103.72Price / CashN/A180.4637.7358.48Price / Book1.005.939.536.61Net Income-$3.96M$31.83M$3.26B$265.56M7 Day Performance0.91%1.89%2.10%1.95%1 Month Performance-20.50%1.33%2.82%-0.37%1 Year Performance-32.88%8.84%30.56%19.02% Xenetic Biosciences Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)XBIOXenetic Biosciences1.0072 of 5 stars$2.89+2.3%N/A-33.3%$4.35M$2.50M-1.444Positive NewsShort Interest ↑SYBXSynlogicN/A$1.46+5.8%N/A-3.3%$17.08M$10K-0.5880Short Interest ↑Gap UpHigh Trading VolumeLSBLakeShore Biopharma0.6383 of 5 stars$0.81+0.9%N/A-81.2%$16.82M$85.67M0.00773HOTHHoth Therapeutics2.1483 of 5 stars$1.27+9.5%$4.00+215.0%+79.1%$16.78MN/A-1.114News CoveragePositive NewsAnalyst DowngradeShort Interest ↓IMNNImunon1.2809 of 5 stars$6.84-3.4%$232.50+3,299.1%-65.1%$16.69M$500K-0.5330MTEXMannatech0.2782 of 5 stars$8.71+8.9%N/A+18.8%$16.55M$117.87M-87.10250Positive NewsGap UpLEXXLexaria Bioscience3.3843 of 5 stars$0.83+1.5%$4.00+379.9%-73.8%$16.30M$460K-1.247LPCNLipocine2.4606 of 5 stars$2.97+0.7%$9.00+203.0%-16.2%$16.10M$11.20M-3.4110News CoveragePositive NewsAnalyst ForecastAnalyst RevisionCLDICalidi Biotherapeutics0.7442 of 5 stars$5.29+5.0%N/A-89.9%$16.01MN/A0.0038News CoverageBLRXBioLineRx3.4175 of 5 stars$3.75+0.8%$26.00+593.3%-87.0%$15.98M$28.94M-0.4340NRSNNeuroSense Therapeutics2.5636 of 5 stars$1.12-6.7%$14.00+1,150.0%+41.8%$15.31MN/A-2.0710News CoveragePositive NewsShort Interest ↑Gap DownHigh Trading Volume Related Companies and Tools Related Companies SYBX Competitors LSB Competitors HOTH Competitors IMNN Competitors MTEX Competitors LEXX Competitors LPCN Competitors CLDI Competitors BLRX Competitors NRSN Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:XBIO) was last updated on 8/23/2025 by MarketBeat.com Staff From Our PartnersBONUS GUIDE - Ben Stein Prepares For the Next Financial CrisisWith inflation high, debt soaring, and global tensions rising, a financial storm may be brewing. 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