NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $28.67 +0.03 (+0.10%) As of 05/23/2025 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsOwnershipRatingsBuy This Stock About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get SBIO alerts:Sign Up Key Stats Today's Range$28.14▼$28.6850-Day Range$23.59▼$31.0552-Week Range$22.33▼$42.73Volume5,737 shsAverage Volume11,804 shsMarket Capitalization$81.71 millionAssets Under Management$81.02 millionDividend Yield4.08%Net Expense Ratio0.50%Aggregate RatingModerate Buy ETF OverviewThe ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS.Read More… ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.57%0.57%0.52%0.53%Other Expenses0.00%0.30%0.48%0.56%0.52%Total Expense0.50%0.70%0.72%0.73%0.71%Fee Waiver0.00%-0.45%-0.49%-0.65%-0.54%Net Expense0.50%0.61%0.63%0.58%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Email Address SBIO ETF News HeadlinesSBIO ETF: Betting On Medical BreakthroughsDecember 14, 2024 | seekingalpha.comAdvacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space IndustryOctober 10, 2024 | businesswire.comBuffett’s favorite chart just hit 209% – here’s what that means for goldA Historic Gold Announcement Is About to Rock Wall Street For months, sharp-eyed analysts have watched the quiet buildup behind the scenes. Now, in just days, the floodgates are set to open. The greatest investor of all time is about to validate what Garrett Goggin has been saying for months: Gold is entering a once-in-a-generation mania. Front-running Buffett has never been more urgent — and four tiny miners could be your ticket to 100X gains.May 25, 2025 | Golden Portfolio (Ad)Why Biotech ETFs Are Beating the MarketSeptember 7, 2024 | msn.comALPS Medical Breakthroughs ETF (^SBIO-IV)July 19, 2024 | finance.yahoo.comHow does spaceflight lead to medical breakthroughs? Veteran astronaut explainsMay 22, 2024 | msn.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $33.03 at the beginning of the year. Since then, SBIO stock has decreased by 13.2% and is now trading at $28.67. View the best growth stocks for 2025 here. Who are ALPS Medical Breakthroughs ETF's major shareholders? Top institutional investors of ALPS Medical Breakthroughs ETF include Phoenix Financial Ltd. (50.87%), DAVENPORT & Co LLC (25.98%), Jones Financial Companies Lllp (0.96%) and NTV Asset Management LLC (0.94%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/31/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings104 Fund Statistics Assets Under Management$81.02 million Average Daily Volume$14,236.10 Discount/Premium-0.01% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Portfolio Solutions Distributor, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableN/A Short Interest3,500 shs Miscellaneous Outstanding Shares2,850,000Beta0.77 Creation Unit50,000 Creation Fee$500.00 7 Energy Stocks to Buy and Hold ForeverWith the proliferation of data centers and electric vehicles, the electric grid will only get more strained. Download this report to learn how energy stocks can play a role in your portfolio as the global demand for energy continues to grow.Get This Free Report Top 10 SBIO HoldingsVerona Pharma (NASDAQ:VRNA)Holding Weight: 5.30%Axsome Therapeutics (NASDAQ:AXSM)Holding Weight: 4.55%Alkermes (NASDAQ:ALKS)Holding Weight: 4.47%Rhythm Pharmaceuticals (NASDAQ:RYTM)Holding Weight: 3.80%Akero Therapeutics (NASDAQ:AKRO)Holding Weight: 3.16%PTC Therapeutics (NASDAQ:PTCT)Holding Weight: 2.98%Avidity Biosciences (NASDAQ:RNA)Holding Weight: 2.91%Zai Lab (NASDAQ:ZLAB)Holding Weight: 2.75%Crinetics Pharmaceuticals (NASDAQ:CRNX)Holding Weight: 2.69%Merus (NASDAQ:MRUS)Holding Weight: 2.56%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 5/25/2025 by MarketBeat.com Staff From Our PartnersGold Hits New Highs as Global Markets SpiralWhen Trump took office in 2017, gold was just $1,100 an ounce. 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