NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $39.96 +0.11 (+0.28%) Closing price 04:10 PM EasternExtended Trading$39.93 -0.03 (-0.08%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsOwnershipRatingsShort InterestBuy This Stock About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SBIO alerts:Sign Up Key Stats Today's Range$39.88▼$40.4250-Day Range$32.65▼$39.8552-Week Range$22.33▼$42.73Volume9,936 shsAverage Volume14,030 shsMarket Capitalization$95.10 millionAssets Under Management$95.56 millionDividend Yield2.93%Net Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.56%0.56%0.51%0.53%Other Expenses0.00%0.47%0.56%0.59%0.56%Total Expense0.50%0.75%0.76%0.74%0.73%Fee Waiver0.00%-0.67%-0.66%-0.71%-0.63%Net Expense0.50%0.60%0.63%0.58%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. SBIO ETF News HeadlinesCreator Television® and MADCOOL Media Partner to Bring Culture-Driving Creator Content to TelevisionSeptember 22, 2025 | prnewswire.comALPS MEDICAL BREAKTHROUGHS ETF ETFs - Markets InsiderJuly 3, 2025 | markets.businessinsider.comGOLD ALERTGold has shattered records, soaring past $3,800 an ounce... But Stansberry Senior Partner Dr. David "Doc" Eifrig says history shows it could be on the verge of its biggest bull run in over half a century.October 6 at 2:00 AM | Stansberry Research (Ad)SBIO ETF: Betting On Medical BreakthroughsDecember 14, 2024 | seekingalpha.comAdvacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space IndustryOctober 10, 2024 | businesswire.comWhy Biotech ETFs Are Beating the MarketSeptember 7, 2024 | msn.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $33.03 at the beginning of the year. Since then, SBIO stock has increased by 21.0% and is now trading at $39.96. How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AU Optronics (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/31/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings107 Fund Statistics Assets Under Management$95.56 million Average Daily Volume$13.99 thousand Discount/Premium0.03% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Distributors, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableOptionable Options Volume58 Put Options8 Call Options58 Short Interest20,100 shs Miscellaneous Outstanding Shares2,380,000Beta0.92 Creation Unit50,000 Creation Fee$500.00 The Next 7 Blockbuster Stocks for Growth InvestorsWondering what the next stocks will be that hit it big, with solid fundamentals? Enter your email address to see which stocks MarketBeat analysts could become the next blockbuster growth stocks.Get This Free Report Top 10 SBIO HoldingsRhythm Pharmaceuticals (NASDAQ:RYTM)Holding Weight: 3.61%Avidity Biosciences (NASDAQ:RNA)Holding Weight: 3.34%Axsome Therapeutics (NASDAQ:AXSM)Holding Weight: 3.15%Cytokinetics (NASDAQ:CYTK)Holding Weight: 3.15%Metsera (NASDAQ:MTSR)Holding Weight: 2.88%Nuvalent (NASDAQ:NUVL)Holding Weight: 2.77%Merus (NASDAQ:MRUS)Holding Weight: 2.68%Krystal Biotech (NASDAQ:KRYS)Holding Weight: 2.47%Crinetics Pharmaceuticals (NASDAQ:CRNX)Holding Weight: 2.40%PTC Therapeutics (NASDAQ:PTCT)Holding Weight: 2.40%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 10/6/2025 by MarketBeat.com Staff From Our PartnersArizona-made nanochips the new millionaire maker?George Gilder handed President Reagan the first microchip that helped create $6.5 trillion in wealth over the ...Banyan Hill Publishing | Sponsored$100 Trillion “AI Metal” Found in American Ghost TownJeff Brown recently traveled to a ghost town in the middle of an American desert… To investigate what could...Brownstone Research | SponsoredStunning new initiative unfolding in the White House?what I just learned about what’s unfolding in the White House is truly stunning… And you need to see it for...Paradigm Press | SponsoredThe $20 stock that could make silicon chips obsolete$2 TRILLION Quantum Gold Rush While everyone fights over expensive AI stocks... 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