SPDR S&P Biotech ETF Rating $104.99 -1.53 (-1.44%) Closing price 10/10/2025 04:10 PM EasternExtended Trading$104.48 -0.51 (-0.49%) As of 10/10/2025 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ratings Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock SPDR S&P Biotech ETF Aggregate Rating and Price Target (2025)How MarketBeat Aggregates ETF Rating and Price TargetMarketBeat calculates the aggregate rating and price target for an ETF by considering the weight of each stock in its portfolio. These ratings and price targets are based on the most recent ratings given by Wall Street analysts over the past year. The aggregate rating reviews the ETF's overall performance and is categorized as strong sell, sell, reduce, hold, moderate buy, buy, or strong buy. The aggegreate price target represents the average potential upside for the consensus price target of individual holdings in the ETF.XBI Aggregate RatingModerate Buy 2.65Holdings in XBI have an aggregate rating of Moderate Buy based on 513 analyst ratings issued in the past year covering 25 companies (46.3% of the portfolio).XBI Aggregate Price Target$104.99High Prediction$104.99Average Prediction$104.99Low Prediction$104.99Holdings in XBI have an aggregate price target of $104.99 and a range of $104.99 to $104.99 covering 25 companies (46.3% of the portfolio).XBI Consensus Ratings of HoldingsStrong Buy0 Strong Buy rating(s)Buy0 Buy rating(s)Moderate Buy19 Moderate Buy rating(s)Hold6 Hold rating(s)Reduce0 Reduce rating(s)Sell0 Sell rating(s)Strong Sell0 Strong Sell rating(s) Ratings for Stocks Held by SPDR S&P Biotech ETF Strong Sell Sell Reduce Hold Moderate Buy Buy Strong Buy Ratings for the Top 25 XBI Holdings Export to ExcelWeight In ETFCompanyShare PriceMarketRank™Consensus Rating ScoreConsensus Price TargetPossible UpsideNumber of RatingsIndicator(s)ViewRatings2.48%CRSPCRISPR Therapeutics$73.07-2.5%1.6614 of 5 stars2.42$71.50 -2.1%19News CoverageAnalyst Forecast2.07%MRNAModerna$26.83-2.5%4.2253 of 5 stars2.00$41.81 55.8%23Analyst Forecast1.99%UTHRUnited Therapeutics$440.00-1.2%4.1986 of 5 stars2.67$457.21 3.9%15Analyst ForecastInsider Trade1.99%ABBVAbbVie$230.88+0.1%4.5794 of 5 stars2.79$231.90 0.4%28Positive NewsAnalyst ForecastAnalyst Revision1.95%EXELExelixis$38.15-1.1%4.8255 of 5 stars2.63$44.42 16.4%24Trending NewsAnalyst ForecastAnalyst Revision1.93%BIIBBiogen$146.57-2.0%4.6028 of 5 stars2.32$180.15 22.9%31Trending NewsAnalyst ForecastAnalyst Revision1.92%REGNRegeneron Pharmaceuticals$564.63-0.9%4.7293 of 5 stars2.79$817.46 44.8%29Trending NewsAnalyst ForecastAnalyst Revision1.90%IONSIonis Pharmaceuticals$69.97-0.4%3.4595 of 5 stars2.80$78.28 11.9%20Trending NewsAnalyst ForecastInsider Trade1.90%AMGNAmgen$290.13-1.8%4.5468 of 5 stars2.35$309.42 6.6%20Positive NewsAnalyst UpgradeAnalyst Revision1.87%VRTXVertex Pharmaceuticals$407.79-1.7%4.8292 of 5 stars2.62$494.38 21.2%29Positive NewsAnalyst ForecastAnalyst Revision1.86%INSMInsmed$162.33-1.3%3.02 of 5 stars2.86$149.06 -8.2%21Analyst Forecast1.86%MDGLMadrigal Pharmaceuticals$429.60+0.3%4.3596 of 5 stars2.73$525.88 22.4%11News CoverageAnalyst Forecast1.82%EXASExact Sciences$58.34-1.9%4.4164 of 5 stars2.92$69.19 18.6%24Trending NewsAnalyst ForecastInsider Trade1.81%BMRNBioMarin Pharmaceutical$52.32-2.8%4.8929 of 5 stars2.55$93.26 78.3%22Trending NewsAnalyst ForecastAnalyst Revision1.81%RVMDRevolution Medicines$48.24+1.3%4.0625 of 5 stars2.93$74.64 54.7%15Analyst Forecast1.79%BBIOBridgeBio Pharma$55.49+1.3%4.0573 of 5 stars2.89$63.94 15.2%18Analyst ForecastInsider Trade1.78%INCYIncyte$83.80-1.1%4.3754 of 5 stars2.22$84.79 1.2%18Analyst Forecast1.75%ALNYAlnylam Pharmaceuticals$459.66+0.6%3.9547 of 5 stars2.82$457.16 -0.5%28Analyst Forecast1.72%NBIXNeurocrine Biosciences$136.63-1.3%4.7633 of 5 stars2.80$163.44 19.6%20Analyst Forecast1.72%TGTXTG Therapeutics$33.76-3.5%4.4339 of 5 stars2.67$49.00 45.1%6Analyst ForecastAnalyst Revision1.71%GILDGilead Sciences$117.18+0.4%4.8791 of 5 stars2.86$118.08 0.8%29Trending NewsAnalyst ForecastAnalyst Revision1.69%RNAAvidity Biosciences$49.77-2.0%1.9451 of 5 stars2.95$68.32 37.3%20Analyst ForecastInsider Trade1.68%NTRANatera$169.27-2.2%2.8366 of 5 stars2.90$192.88 13.9%20Analyst Forecast1.68%HALOHalozyme Therapeutics$64.10-1.6%4.693 of 5 stars2.31$70.44 9.9%13Trending NewsAnalyst UpgradeAnalyst Revision1.65%ROIVRoivant Sciences$16.04-0.5%3.4089 of 5 stars2.80$19.94 24.3%10Analyst ForecastInsider Trade This page (NYSEARCA:XBI) was last updated on 10/12/2025 by MarketBeat.com Staff From Our PartnersURGENT: The Market's 3 Red Flags Are FlashingHere’s the uncomfortable truth: The smartest investors in the world are already preparing for a crash befor...StockEarnings | Sponsored$100 Trillion “AI Metal” Found in American Ghost TownJeff Brown recently traveled to a ghost town in the middle of an American desert… To investigate what could...Brownstone Research | Sponsored7 market signals flashing red right nowRight now, the same 7 key indicators that predicted 1929, the 1970s stagflation, and the 2008 meltdown are all...American Alternative | Sponsored1 Hour Once A DayMy top income trading expert, Dave Aquino, just released a 1-hour trading strategy designed specifically to he...Base Camp Trading | SponsoredAn $8 trillion-dollar discovery 17,000 ft underwater A strange rock pulled from the ocean floor may hold the key to a $16 trillion resource boom. 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