SPDR S&P Biotech ETF Rating $85.28 +1.01 (+1.20%) Closing price 04:10 PM EasternExtended Trading$85.26 -0.02 (-0.02%) As of 06:54 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ratings Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock SPDR S&P Biotech ETF Aggregate Rating and Price Target (2025)How MarketBeat Aggregates ETF Rating and Price TargetMarketBeat calculates the aggregate rating and price target for an ETF by considering the weight of each stock in its portfolio. These ratings and price targets are based on the most recent ratings given by Wall Street analysts over the past year. The aggregate rating reviews the ETF's overall performance and is categorized as strong sell, sell, reduce, hold, moderate buy, buy, or strong buy. The aggegreate price target represents the average potential upside for the consensus price target of individual holdings in the ETF.XBI Aggregate RatingModerate Buy 2.77Holdings in XBI have an aggregate rating of Moderate Buy based on 1,441 analyst ratings issued in the past year covering 123 companies (99.9% of the portfolio).XBI Aggregate Price Target$85.28High Prediction$85.28Average Prediction$85.28Low Prediction$85.28Holdings in XBI have an aggregate price target of $85.28 and a range of $85.28 to $85.28 covering 123 companies (99.9% of the portfolio).XBI Consensus Ratings of HoldingsStrong Buy0 Strong Buy rating(s)Buy53 Buy rating(s)Moderate Buy55 Moderate Buy rating(s)Hold15 Hold rating(s)Reduce0 Reduce rating(s)Sell0 Sell rating(s)Strong Sell0 Strong Sell rating(s) Ratings for Stocks Held by SPDR S&P Biotech ETF Strong Sell Sell Reduce Hold Moderate Buy Buy Strong Buy Ratings for the Top 100 XBI Holdings Export to ExcelWeight In ETFCompanyShare PriceMarketRank™Consensus Rating ScoreConsensus Price TargetPossible UpsideNumber of RatingsIndicator(s)ViewRatings3.26%ALNYAlnylam Pharmaceuticals$302.46-0.5%3.9352 of 5 stars2.77$319.17 5.5%263.13%EXASExact Sciences$56.18+2.8%4.3813 of 5 stars2.95$70.90 26.2%22Positive News3.03%BPMCBlueprint Medicines$127.970.9112 of 5 stars2.32$129.35 1.1%22High Trading Volume2.95%NBIXNeurocrine Biosciences$124.77-0.8%4.9498 of 5 stars2.86$162.00 29.8%22Analyst Revision2.87%NTRANatera$165.22+0.6%2.2078 of 5 stars3.00$184.63 11.7%152.74%UTHRUnited Therapeutics$281.36-14.3%4.965 of 5 stars2.69$393.00 39.7%13Positive NewsAnalyst RevisionGap DownHigh Trading Volume2.50%INSMInsmed$90.93+28.7%3.2324 of 5 stars3.00$98.93 8.8%17Trending NewsAnalyst ForecastAnalyst RevisionGap UpHigh Trading Volume2.49%INCYIncyte$70.07+0.3%4.2963 of 5 stars2.17$72.53 3.5%18Positive News2.47%GILDGilead Sciences$110.09-2.6%4.7635 of 5 stars2.78$110.55 0.4%27Positive NewsAnalyst RevisionGap Down2.42%BIIBBiogen$135.49+1.0%4.797 of 5 stars2.38$191.30 41.2%32Positive News2.38%AMGNAmgen$293.43+1.2%4.3302 of 5 stars2.38$309.22 5.4%24Positive NewsAnalyst Revision2.36%EXELExelixis$42.52-0.9%4.5476 of 5 stars2.47$39.35 -7.4%19Positive News2.32%VRTXVertex Pharmaceuticals$451.52+1.2%4.2859 of 5 stars2.57$515.04 14.1%30Positive News2.28%ABBVAbbVie$189.31+0.1%4.8738 of 5 stars2.81$211.29 11.6%27Positive NewsAnalyst ForecastAnalyst Revision2.00%MRNAModerna$27.68-1.6%4.4329 of 5 stars2.04$53.58 93.6%231.95%MDGLMadrigal Pharmaceuticals$282.32+0.7%4.2548 of 5 stars2.90$416.33 47.5%10Positive NewsAnalyst Revision1.84%REGNRegeneron Pharmaceuticals$523.53+1.1%4.8311 of 5 stars2.85$836.48 59.8%26Analyst Forecast1.78%BMRNBioMarin Pharmaceutical$57.48+1.1%4.8962 of 5 stars2.74$93.45 62.6%23Positive NewsAnalyst Revision1.71%BBIOBridgeBio Pharma$40.09+2.7%4.5361 of 5 stars2.92$57.36 43.1%12Analyst Upgrade1.59%RVMDRevolution Medicines$41.98+3.4%3.8814 of 5 stars3.00$67.08 59.8%121.55%TGTXTG Therapeutics$39.43-1.0%3.1447 of 5 stars2.80$40.80 3.5%5Analyst Revision1.48%HALOHalozyme Therapeutics$53.77-1.1%4.863 of 5 stars2.17$61.90 15.1%121.44%IONSIonis Pharmaceuticals$36.84+0.2%4.2782 of 5 stars2.65$56.67 53.8%20Positive News1.32%ROIVRoivant Sciences$11.37+2.6%2.3488 of 5 stars3.00$17.50 53.9%41.29%CRSPCRISPR Therapeutics$42.94+2.0%3.1665 of 5 stars2.50$71.75 67.1%18Analyst RevisionHigh Trading Volume1.24%SWTXSpringWorks Therapeutics$46.740.0%1.5144 of 5 stars2.13$52.57 12.5%8Positive News1.15%RNAAvidity Biosciences$33.62+2.9%2.2359 of 5 stars3.00$67.50 100.8%14Trending NewsAnalyst Forecast1.15%VKTXViking Therapeutics$29.14+5.7%4.5552 of 5 stars3.00$87.15 199.1%14Options Volume1.12%ALKSAlkermes$31.06-0.3%4.5346 of 5 stars2.77$38.85 25.1%13Insider Trade1.10%PCVXVaxcyte$37.202.3958 of 5 stars3.10$136.50 266.9%101.10%CYTKCytokinetics$34.54+4.3%4.0638 of 5 stars2.93$70.92 105.3%15Analyst ForecastAnalyst Revision1.09%ADMAADMA Biologics$20.860.0%2.218 of 5 stars3.25$24.25 16.3%4Analyst Revision1.03%ACADACADIA Pharmaceuticals$22.20-0.4%3.5995 of 5 stars2.69$26.79 20.7%16Analyst Revision0.97%SMMTSummit Therapeutics$22.08+2.4%2.9912 of 5 stars3.09$37.40 69.4%11Analyst RevisionGap Up0.94%NUVLNuvalent$79.46+4.4%2.4678 of 5 stars2.90$115.50 45.4%10Positive News0.90%AKROAkero Therapeutics$54.52-0.3%4.1806 of 5 stars3.00$82.50 51.3%8Insider TradeOptions Volume0.88%RYTMRhythm Pharmaceuticals$67.37+1.0%3.7185 of 5 stars3.00$76.62 13.7%130.88%SRPTSarepta Therapeutics$39.07-1.6%4.8479 of 5 stars2.87$122.61 213.8%230.87%ACLXArcellx$66.61-0.4%2.0519 of 5 stars3.07$111.33 67.1%14Positive NewsAnalyst Revision0.84%SLNOSoleno Therapeutics$79.80+2.7%4.8593 of 5 stars3.11$106.78 33.8%9Positive NewsAnalyst Revision0.82%APLSApellis Pharmaceuticals$19.58+1.0%4.6334 of 5 stars2.62$40.05 104.6%21Analyst Revision0.79%SRRKScholar Rock$34.42+1.0%4.1153 of 5 stars3.14$42.67 24.0%7Positive News0.78%CRNXCrinetics Pharmaceuticals$33.08+2.5%3.5999 of 5 stars2.91$74.56 125.4%11Positive NewsAnalyst Revision0.77%RAREUltragenyx Pharmaceutical$37.51+1.3%3.8234 of 5 stars2.92$88.77 136.7%13Analyst Revision0.76%ARWRArrowhead Pharmaceuticals$16.97+2.4%3.5513 of 5 stars2.75$43.71 157.6%80.74%TWSTTwist Bioscience$34.45+3.3%4.2418 of 5 stars2.70$50.40 46.3%100.73%AGIOAgios Pharmaceuticals$34.51+2.5%4.1109 of 5 stars2.63$56.50 63.7%8Positive NewsAnalyst Revision0.72%KRYSKrystal Biotech$138.21+1.6%4.5719 of 5 stars3.00$211.13 52.8%9Analyst Revision0.71%VCYTVeracyte$27.88+0.1%4.2096 of 5 stars2.70$40.90 46.7%100.67%PTCTPTC Therapeutics$51.74+0.1%3.209 of 5 stars2.64$63.75 23.2%14Analyst Revision0.65%BCRXBioCryst Pharmaceuticals$11.01-0.9%4.3591 of 5 stars2.89$16.56 50.4%9Analyst Revision0.64%VERAVera Therapeutics$22.62+1.9%2.8491 of 5 stars3.10$65.00 187.4%10High Trading Volume0.62%RXRXRecursion Pharmaceuticals$5.45+1.5%1.7713 of 5 stars2.33$7.60 39.4%6News CoverageHigh Trading Volume0.62%CPRXCatalyst Pharmaceuticals$26.31+1.8%4.6478 of 5 stars3.25$32.83 24.8%80.62%IDYAIDEAYA Biosciences$22.63+4.2%3.4322 of 5 stars2.93$54.27 139.8%14Analyst Revision0.61%KYMRKymera Therapeutics$48.60+3.1%1.9801 of 5 stars3.00$59.82 23.1%180.57%MIRMMirum Pharmaceuticals$48.98+4.1%2.9883 of 5 stars3.17$60.73 24.0%12Positive News0.55%GRALGrail$42.15+5.3%0.3814 of 5 stars2.25$31.50 -25.3%40.54%TVTXTravere Therapeutics$15.13+1.5%2.5684 of 5 stars2.87$31.79 110.1%150.53%PTGXProtagonist Therapeutics$56.37+1.2%2.2478 of 5 stars3.00$65.44 16.1%9Analyst Upgrade0.52%ARQTArcutis Biotherapeutics$13.89-2.3%2.2152 of 5 stars2.83$18.80 35.3%6Positive News0.52%CLDXCelldex Therapeutics$20.92+1.0%1.9813 of 5 stars2.90$53.90 157.6%10Positive NewsAnalyst Revision0.51%IMVTImmunovant$16.74+2.8%1.4005 of 5 stars2.90$38.33 129.0%10Positive NewsAnalyst Revision0.47%NVAXNovavax$7.20-2.8%3.8143 of 5 stars2.43$19.00 163.9%7Positive News0.46%BEAMBeam Therapeutics$18.08-0.5%2.981 of 5 stars3.00$48.75 169.6%150.46%VCELVericel$45.70+4.3%3.132 of 5 stars3.00$61.14 33.8%7Positive News0.45%SNDXSyndax Pharmaceuticals$11.24+1.4%3.2162 of 5 stars2.91$35.91 219.5%11Positive News0.45%CGONCG Oncology$27.48+1.8%2.2741 of 5 stars3.00$58.22 111.9%11Positive News0.45%DYNDyne Therapeutics$14.78+2.6%2.7498 of 5 stars3.07$45.54 208.1%150.45%BHVNBiohaven$16.78-1.7%2.7864 of 5 stars3.07$59.46 254.4%15Analyst Revision0.43%DNLIDenali Therapeutics$15.26+4.2%4.3306 of 5 stars3.06$33.71 120.9%17Positive NewsAnalyst Revision0.41%CDNACareDx$19.85+0.7%3.6646 of 5 stars2.67$30.33 52.8%6Positive News0.39%DVAXDynavax Technologies$10.43+1.5%4.4714 of 5 stars2.50$24.00 130.1%4News Coverage0.39%IRONDisc Medicine$53.07+3.2%2.0377 of 5 stars3.09$98.80 86.2%11Positive NewsInsider TradeAnalyst Revision0.37%FOLDAmicus Therapeutics$6.11+1.3%3.7199 of 5 stars2.70$16.22 165.5%100.37%APGEApogee Therapeutics$42.02+4.7%2.03 of 5 stars3.00$94.60 125.1%50.36%ARDXArdelyx$3.74-0.5%4.1525 of 5 stars2.90$10.39 177.8%10Positive NewsAnalyst Revision0.35%VRDNViridian Therapeutics$15.42+3.8%1.7762 of 5 stars2.91$36.70 138.0%11Positive News0.34%JANXJanux Therapeutics$26.24+1.2%1.728 of 5 stars3.09$95.25 263.0%11Analyst Revision0.33%ETNB89bio$10.28-2.7%2.5061 of 5 stars3.00$26.43 157.1%8Positive NewsGap Up0.32%NRIXNurix Therapeutics$12.79+2.0%1.7568 of 5 stars2.83$30.18 135.9%180.31%NTLAIntellia Therapeutics$8.47+2.3%4.606 of 5 stars2.67$34.95 312.6%21Analyst Revision0.30%GERNGeron$1.60-1.2%3.0959 of 5 stars2.78$5.06 216.4%9Positive News0.29%QUREuniQure$16.34-3.3%1.7382 of 5 stars2.91$37.82 131.4%11Analyst Revision0.28%PRAXPraxis Precision Medicines$45.85+3.0%2.5798 of 5 stars2.80$109.90 139.7%100.27%MNKDMannKind$3.92-10.3%3.0284 of 5 stars3.25$10.00 155.1%8News CoverageAnalyst RevisionGap DownHigh Trading Volume0.26%SPRYARS Pharmaceuticals$14.69+1.1%2.7436 of 5 stars3.17$31.00 111.0%6Positive NewsAnalyst Revision0.26%SYRESpyre Therapeutics$18.56+8.2%2.0703 of 5 stars3.25$53.40 187.7%80.25%RCUSArcus Biosciences$10.04+1.9%2.7585 of 5 stars2.90$24.13 140.4%10Analyst Revision0.23%AVXLAnavex Life Sciences$8.12+2.4%3.9043 of 5 stars3.33$44.00 441.9%3Positive News0.22%COGTCogent Biosciences$7.42+7.5%1.4824 of 5 stars2.75$14.57 96.4%8Positive NewsHigh Trading Volume0.22%IMNMImmunome$9.57+3.2%2.3606 of 5 stars3.00$23.33 143.8%6Positive News0.21%IBRXImmunityBio$3.34-2.9%1.9758 of 5 stars3.20$12.25 266.8%5High Trading Volume0.21%VIRVir Biotechnology$5.42-0.2%2.9454 of 5 stars2.86$32.86 506.2%7Positive News0.20%CAPRCapricor Therapeutics$13.89+3.8%1.6525 of 5 stars3.00$35.50 155.6%6Analyst Revision0.20%DAWNDay One Biopharmaceuticals$6.98-1.4%1.7047 of 5 stars3.13$30.57 338.0%80.20%KURAKura Oncology$6.81+1.2%4.5924 of 5 stars2.93$24.50 259.8%14Analyst Revision0.19%KROSKeros Therapeutics$13.75-2.4%3.1615 of 5 stars2.50$30.56 122.2%14News CoverageAnalyst DowngradeGap Down0.18%ALTAltimmune$6.74+13.3%2.8069 of 5 stars3.00$20.20 199.7%7Positive NewsGap UpHigh Trading Volume0.18%IOVAIovance Biotherapeutics$2.38+7.7%4.5452 of 5 stars2.50$13.30 458.8%12Trending NewsHigh Trading Volume This page (NYSEARCA:XBI) was last updated on 6/10/2025 by 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