Affinity Asset Advisors, LLC Top Holdings and 13F Report (2025) About Affinity Asset Advisors, LLCInvestment ActivityAffinity Asset Advisors, LLC has $732.19 million in total holdings as of June 30, 2025.Affinity Asset Advisors, LLC owns shares of 88 different stocks, but just 29 companies or ETFs make up 80% of its holdings.Approximately 24.02% of the portfolio was purchased this quarter.About 73.04% of the portfolio was sold this quarter.This quarter, Affinity Asset Advisors, LLC has purchased 91 new stocks and bought additional shares in 19 stocks.Affinity Asset Advisors, LLC sold shares of 27 stocks and completely divested from 22 stocks this quarter.Largest Holdings Verona Pharma PLC American Depositary Share $57,693,800Insmed $47,804,000Xenon Pharmaceuticals $34,430,000Arcellx $32,595,750Blueprint Medicines $32,045,000 Largest New Holdings this Quarter 09627Y109 - Blueprint Medicines $32,045,000 HoldingH17182108 - CRISPR Therapeutics $9,728,000 Holding92332V107 - Ventyx Biosciences $9,707,429 Holding29337E102 - Enliven Therapeutics $8,024,000 Holding682143AK8 - OMEROS CORP $7,068,530 Holding Largest Purchases this Quarter Insmed 335,000 shares (about $33.71M)Blueprint Medicines 250,000 shares (about $32.05M)Exelixis 465,000 shares (about $20.49M)CRISPR Therapeutics 200,000 shares (about $9.73M)Ventyx Biosciences 4,536,182 shares (about $9.71M) Largest Sales this Quarter APOGEE THERAPEUTICS INC 456,800 shares (about $19.84M)Merus 251,962 shares (about $13.25M)Centessa Pharmaceuticals 646,500 shares (about $8.50M)Inozyme Pharma 2,118,351 shares (about $8.47M)Amgen 30,000 shares (about $8.38M) Sector Allocation Over TimeMap of 500 Largest Holdings ofAffinity Asset Advisors, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorVRNAVerona Pharma PLC American Depositary Share$57,693,800$472,900 ▼-0.8%610,0007.9%MedicalINSMInsmed$47,804,000$33,714,400 ▲239.3%475,0006.5%MedicalXENEXenon Pharmaceuticals$34,430,000$7,141,878 ▼-17.2%1,100,0004.7%MedicalACLXArcellx$32,595,750$2,304,750 ▼-6.6%495,0004.5%MedicalBPMCBlueprint Medicines$32,045,000$32,045,000 ▲New Holding250,0004.4%MedicalNUVLNuvalent$31,664,500$3,433,500 ▼-9.8%415,0004.3%MedicalAPOGEE THERAPEUTICS INC$30,157,749$19,838,824 ▼-39.7%694,3994.1%COMALKSAlkermes$28,610,0000.0%1,000,0003.9%MedicalEXELExelixis$26,445,000$20,494,875 ▲344.4%600,0003.6%MedicalPTGXProtagonist Therapeutics$24,318,800$7,323,275 ▼-23.1%440,0003.3%MedicalMDGLMadrigal Pharmaceuticals$24,211,2000.0%80,0003.3%MedicalTEVATeva Pharmaceutical Industries$23,464,0000.0%1,400,0003.2%MedicalLEXEO THERAPEUTICS INC$14,429,207$8,476,065 ▲142.4%3,589,3552.0%COMTVTXTravere Therapeutics$14,356,000$1,480,000 ▼-9.3%970,0002.0%MedicalESTAEstablishment Labs$14,301,999$2,343,199 ▲19.6%334,8632.0%MedicalTRVITrevi Therapeutics$13,861,297$7,023,797 ▲102.7%2,534,0581.9%MedicalWVEWAVE Life Sciences$13,002,002$1,139,502 ▲9.6%2,000,3081.8%MedicalVERAVera Therapeutics$12,840,200$1,770,369 ▼-12.1%545,0001.8%MedicalMLYSMineralys Therapeutics$12,177,000$5,412,000 ▼-30.8%900,0001.7%MedicalCNTACentessa Pharmaceuticals$11,828,129$8,495,010 ▼-41.8%900,1621.6%MedicalKARYOPHARM THERAPEUTICS INC$11,620,4800.0%15,250,0001.6%NOTE 3.000%10/1AMGNAmgen$11,168,400$8,376,300 ▼-42.9%40,0001.5%MedicalNRIXNurix Therapeutics$11,021,192$1,787,672 ▲19.4%967,6201.5%MedicalRZLTRezolute$9,812,000$2,230,000 ▲29.4%2,200,0001.3%MedicalCRSPCRISPR Therapeutics$9,728,000$9,728,000 ▲New Holding200,0001.3%MedicalVTYXVentyx Biosciences$9,707,429$9,707,429 ▲New Holding4,536,1821.3%MedicalSPYRE THERAPEUTICS INC$9,081,970$1,871,250 ▲26.0%606,6781.2%COM NEWELVNEnliven Therapeutics$8,024,000$8,024,000 ▲New Holding400,0001.1%MedicalPRQRProQR Therapeutics$7,139,004$438,600 ▲6.5%3,499,5121.0%MedicalAKBAAkebia Therapeutics$7,098,000$1,638,000 ▲30.0%1,950,0001.0%MedicalOMEROS CORP$7,068,530$7,068,530 ▲New Holding9,025,0001.0%NOTE 9.500% 6/1INZYInozyme Pharma$6,997,436$8,473,404 ▼-54.8%1,749,3591.0%MedicalAUTLAutolus Therapeutics$6,942,6000.0%3,045,0000.9%MedicalORUKA THERAPEUTICS INC$6,765,000$651,492 ▲10.7%603,4790.9%COMTRAVERE THERAPEUTICS INC$6,685,1490.0%7,000,0000.9%NOTE 2.250% 3/0BBIOBridgeBio Pharma$6,477,000$6,477,000 ▼-50.0%150,0000.9%MedicalVRDNViridian Therapeutics$5,452,2000.0%390,0000.7%MedicalAXSMAxsome Therapeutics$5,219,500$5,219,500 ▼-50.0%50,0000.7%MedicalERASErasca$5,188,949$945,220 ▲22.3%4,085,7870.7%MedicalNAMSNewAmsterdam Pharma$4,980,250$4,071,128 ▼-45.0%275,0000.7%MedicalCRESCENT BIOPHARMA INC.$4,519,700$4,519,700 ▲New Holding280,0310.6%COMROIVRoivant Sciences$4,508,000$2,817,500 ▲166.7%400,0000.6%MedicalCRNXCrinetics Pharmaceuticals$4,378,7680.0%152,2520.6%MedicalPCVXVaxcyte$4,063,750$3,251,000 ▲400.0%125,0000.6%MedicalPERCEPTIVE CAP SOLUTIONS COR$3,713,5000.0%350,0000.5%CL A ORD SHSMRUSMerus$3,682,000$13,253,201 ▼-78.3%70,0000.5%MedicalPERSPECTIVE THERAPEUTICS INC$3,612,000$4,039,234 ▼-52.8%1,050,0000.5%COM NEWQUREuniQure$3,275,900$2,300,100 ▼-41.3%235,0000.4%MedicalAVALO THERAPEUTICS INC$3,033,281$245,917 ▼-7.5%607,8720.4%COM NEWOAKTREE ACQUISITION CORP III$2,655,0000.0%250,0000.4%UNIT 10/04/2029JAZZJazz Pharmaceuticals$2,653,000$2,653,000 ▲New Holding25,0000.4%MedicalMONOPAR THERAPEUTICS INC$2,415,150$196,790 ▲8.9%67,5000.3%COM NEWRAPPORT THERAPEUTICS INC$2,269,941$2,269,941 ▲New Holding199,6430.3%COMGERNGeron$2,115,0000.0%1,500,0000.3%MedicalTHRDThird Harmonic Bio$2,009,1000.0%370,0000.3%MedicalCGEMCullinan Therapeutics$1,986,5420.0%263,8170.3%MedicalNAMSWNewAmsterdam Pharma$1,960,000$24,344 ▲1.3%245,0000.3%MedicalELYMEliem Therapeutics$1,860,0000.0%1,500,0000.3%MedicalCAPRCapricor Therapeutics$1,737,750$1,737,750 ▲New Holding175,0000.2%MedicalANTERIS TECHNOLOGIES GLOBAL$1,610,750$132,650 ▲9.0%425,0000.2%COMATXSAstria Therapeutics$1,608,000$1,608,000 ▲New Holding300,0000.2%MedicalNVAXNovavax$1,575,000$1,575,000 ▲New Holding250,0000.2%MedicalNKTXNkarta$1,328,0000.0%800,0000.2%MedicalMIRMMirum Pharmaceuticals$1,256,576$1,272,250 ▼-50.3%24,6920.2%MedicalSVRASavara$1,140,000$1,140,000 ▲New Holding500,0000.2%MedicalOLMAOlema Pharmaceuticals$1,065,000$319,500 ▼-23.1%250,0000.1%MedicalNXTCNextCure$1,059,1950.0%2,302,5980.1%MedicalOMEROmeros$942,000$912,126 ▲3,053.2%314,0000.1%MedicalONKURE THERAPEUTICS INC$831,696$110,344 ▼-11.7%347,9900.1%COM CL AINMBINmune Bio$817,740$817,740 ▲New Holding354,0000.1%MedicalALTAltimmune$774,000$774,000 ▲New Holding200,0000.1%MedicalABIVAX SA$765,000$765,000 ▼-50.0%100,0000.1%SPONSORED ADSKARYOPHARM THERAPEUTICS INC$678,825$678,825 ▲New Holding157,5000.1%COM NEWJADE BIOSCIENCES INC$652,517$652,517 ▲New Holding65,3170.1%COM NEWSTROSutro Biopharma$537,3680.0%752,7220.1%MedicalGALTGalectin Therapeutics$527,500$3,346,882 ▼-86.4%250,0000.1%MedicalTSHATaysha Gene Therapies$462,000$462,000 ▲New Holding200,0000.1%MedicalCNTXContext Therapeutics$339,410$93,408 ▼-21.6%518,0250.0%MedicalENGENE HOLDINGS INC$280,280$280,280 ▲New Holding77,0000.0%COMRPTXRepare Therapeutics$278,0000.0%200,0000.0%MedicalZURAZura Bio$234,5020.0%223,3350.0%MedicalOVIDOvid Therapeutics$220,2140.0%667,5160.0%MedicalRADIOPHARM THERANOSTICS LTD$166,059$134,977 ▼-44.8%35,6350.0%SPONSORED ADSADAGIO MED HLDGS INC$108,000$179,867 ▼-62.5%80,0000.0%COMQ32 BIO INC$41,3880.0%27,7770.0%COMABUSArbutus Biopharma$28,737$28,737 ▲New Holding9,3000.0%MedicalRCKTWRocket Pharmaceuticals$2,1600.0%75,0000.0%MedicalIMTXWImmatics$1120.0%187,2040.0%MedicalSPYSPDR S&P 500 ETF Trust$0$240,537,700 ▼-100.0%00.0%FinanceIWMiShares Russell 2000 ETF$0$59,847,000 ▼-100.0%00.0%FinanceXBISPDR S&P Biotech ETF$0$40,550,000 ▼-100.0%00.0%ETFALNYAlnylam Pharmaceuticals$0$14,851,100 ▼-100.0%00.0%MedicalOMEROS CORP$0$14,275,238 ▼-100.0%00.0%NOTE 5.250% 2/1CORTCorcept Therapeutics$0$7,995,400 ▼-100.0%00.0%MedicalIMVTImmunovant$0$7,348,700 ▼-100.0%00.0%MedicalNBIXNeurocrine Biosciences$0$5,530,000 ▼-100.0%00.0%MedicalEWTXEdgewise Therapeutics$0$4,400,000 ▼-100.0%00.0%MedicalSLNOSoleno Therapeutics$0$3,572,500 ▼-100.0%00.0%MedicalIBRXImmunityBio$0$3,085,250 ▼-100.0%00.0%MedicalCMPXCompass Therapeutics$0$2,776,863 ▼-100.0%00.0%MedicalShowing largest 100 holdings. 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