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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$29.86
-6.1%		$29.72
$10.83
▼
$41.14
$4.09B-0.091.37 million shs1.47 million shs
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
$8.08
$9.79
$4.76
▼
$11.50
$417.72M1.4466,022 shs448,732 shs
The 7 Hottest IPO Stories of 2026 Cover
The 7 Hottest IPO Stories of 2026

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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
-6.10%+8.11%+11.21%+38.05%+142.17%
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
0.00%-17.30%-20.16%-8.49%+61.92%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$29.86
-6.1%		$29.72
$10.83
▼
$41.14
$4.09B-0.091.37 million shs1.47 million shs
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
$8.08
$9.79
$4.76
▼
$11.50
$417.72M1.4466,022 shs448,732 shs
The 7 Hottest IPO Stories of 2026 Cover
The 7 Hottest IPO Stories of 2026

MarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. See which companies are preparing to go public and why investors are watching closely.

Get This Free Report

Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
-6.10%+8.11%+11.21%+38.05%+142.17%
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
0.00%-17.30%-20.16%-8.49%+61.92%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
3.00
Buy$43.7146.40% Upside
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
2.00
Hold$6.00-25.74% Downside

Current Analyst Ratings Breakdown

Latest AMLX and PBYI Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
11/10/2026
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
Weiss Ratings logo
Weiss Ratings
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DowngradeBuy (B-) ➝ Hold (C+)
11/10/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
Mizuho logo
Mizuho
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Boost Price TargetOutperform$38.00 ➝ $39.00
11/5/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
Stifel Nicolaus logo
Stifel Nicolaus
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Set Price Target$45.00
11/5/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
HC Wainwright logo
HC Wainwright
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Initiated CoverageStrong-Buy
11/3/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
Weiss Ratings logo
Weiss Ratings
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Reiterated RatingSell (D-)
10/15/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
Citigroup Inc. logo
Citigroup
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Boost Price TargetBuy$32.00 ➝ $39.00
10/8/2026
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
Weiss Ratings logo
Weiss Ratings
Subscribe to MarketBeat All Access to unlock brokerage rankings
UpgradeHold (C+) ➝ Buy (B-)
8/27/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
Guggenheim logo
Guggenheim
Subscribe to MarketBeat All Access to unlock brokerage rankings
Boost Price TargetBuy$55.00 ➝ $57.00
8/21/2026
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
Weiss Ratings logo
Weiss Ratings
Subscribe to MarketBeat All Access to unlock brokerage rankings
UpgradeHold (C) ➝ Hold (C+)
8/19/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
Guggenheim logo
Guggenheim
Subscribe to MarketBeat All Access to unlock brokerage rankings
Boost Price TargetBuy$40.00 ➝ $55.00
8/19/2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
Robert W. Baird logo
Robert W. Baird
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Boost Price TargetOutperform$28.00 ➝ $52.00
(Data available from 11/13/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$87.37M43.94N/AN/A$5.86 per share5.10
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
$228.40M1.83$0.83 per share9.69$2.84 per share2.85
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
-$144.74M-$1.44N/AN/AN/AN/A-41.54%-38.91%N/A
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
$31.11M$0.4617.5757.71N/A10.26%17.50%11.83%N/A

Latest AMLX and PBYI Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
11/5/2026Q3 2026
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
-$0.3810-$0.38+$0.0010-$0.38$0.06 millionN/A
11/5/2026Q3 2026
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
$0.09$0.15+$0.06$0.11$57.50 million$55.06 million
CompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive Growth
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
N/AN/AN/AN/AN/A
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
N/A
26.81
26.81
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
N/A
3.03
2.64

Institutional Ownership

CompanyInstitutional Ownership
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
95.84%
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
61.29%

Insider Ownership

CompanyInsider Ownership
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
10.90%
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
22.20%
CompanyEmployeesShares OutstandingFree FloatOptionable
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
136128.56 million114.55 millionOptionable
Puma Biotechnology, Inc. stock logo
PBYI
Puma Biotechnology
17951.70 million40.22 millionOptionable

Recent News About These Companies

Puma: 3 Key Takeaways for Long-Term Investors
November 8, 2026  |  fool.comhttps://www.fool.com/earnings/takeaways/2026/11/08/puma-3-key-takeaways-for-long-term-investors/
Puma Biotechnology (NASDAQ:PBYI) Announces Quarterly Earnings Results, Beats Estimates By $0.06 EPS
November 7, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/earnings-puma-biotechnology-nasdaq-pbyi-announces-quarterly-earnings-results-beats-estimates-by-006-eps-2026-11-07/
Puma Biotechnology (PBYI) Q3 2026 Earnings Call Transcript
November 6, 2026  |  fool.comhttps://www.fool.com/earnings/call-transcripts/2026/11/06/puma-biotechnology-pbyi-q3-2026-earnings-call-transcript/
Puma Biotechnology, Inc. (PBYI) Q3 2026 Earnings Call Prepared Remarks Transcript
November 6, 2026  |  seekingalpha.comhttps://seekingalpha.com/article/4963550-puma-biotechnology-inc-pbyi-q3-2026-earnings-call-prepared-remarks-transcript
Transcript : Puma Biotechnology, Inc., Q3 2026 Earnings Call, Nov 05, 2026
November 6, 2026  |  marketscreener.comM
Puma Biotechnology, Inc. Reports Earnings Results for the Third Quarter and Nine Months Ended September 30, 2026
November 6, 2026  |  marketscreener.comM
Puma Biotechnology Q3 Earnings Call Highlights
November 5, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/transcript-puma-biotechnology-q3-earnings-call-highlights-2026-11-05/
Puma Biotechnology Sees Continued Growth and Progress in Q3 2026
November 5, 2026  |  news.themarketisopen.comN
Puma Biotech (PBYI) Tops Q3 Earnings Estimates
November 5, 2026  |  zacks.comhttps://www.zacks.com/stock/news/3025027/puma-biotech-pbyi-tops-q3-earnings-estimates?cid=cs-stocknewsapi-ft-fundamental_analysis|yseop_template_4-3025027
Puma Biotechnology Reports Third Quarter 2026 Financial Results
November 5, 2026  |  businesswire.comhttps://www.businesswire.com/news/home/20261105266638/en/puma-biotechnology-reports-third-quarter-2026-financial-results/
Puma Biotechnology consensus price target raised 20.00% to $6.12
November 2, 2026  |  msn.comhttps://www.msn.com/en-us/news/other/puma-biotechnology-consensus-price-target-raised-2000-to-612/ar-AA2gBpSu
Puma Biotechnology stock gets higher 2026 Nerlynx outlook
October 30, 2026  |  ad-hoc-news.deA
Puma Biotechnology (PBYI) Expected to Post Earnings on Thursday
October 29, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/upcoming-puma-biotechnology-pbyi-expected-to-post-earnings-on-thursday-2026-10-29/
Puma Biotechnology to Host Conference Call to Discuss Third Quarter 2026 Financial Results
October 22, 2026  |  businesswire.comhttps://www.businesswire.com/news/home/20261022355038/en/puma-biotechnology-to-host-conference-call-to-discuss-third-quarter-2026-financial-results/
Puma Biotechnology (NASDAQ:PBYI) Reaches New 12-Month High - Here's Why
October 21, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/price-puma-biotechnology-nasdaq-pbyi-reaches-new-12-month-high-heres-why-2026-10-21/
Will Nerlynx Continue to Aid Puma Biotechnology's Top Line in Q3?
October 20, 2026  |  zacks.comhttps://www.zacks.com/stock/news/3011064/will-nerlynx-continue-to-aid-puma-biotechnology-s-top-line-in-q3?cid=cs-stocknewsapi-ft-analyst_blog|quick_take-3011064
4 Breast Cancer Stocks to Watch During Breast Cancer Awareness Month
October 16, 2026  |  zacks.comhttps://www.zacks.com/stock/news/3009801/4-breast-cancer-stocks-to-watch-during-breast-cancer-awareness-month?cid=cs-stocknewsapi-ft-analyst_blog|investment_ideas-3009801
Puma Biotechnology (NASDAQ:PBYI) Sets New 1-Year High - Here's What Happened
October 15, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/price-puma-biotechnology-nasdaq-pbyi-sets-new-1-year-high-heres-what-happened-2026-10-15/
Puma Biotechnology stock fell 1.76 percent after award news
October 6, 2026  |  ad-hoc-news.deA
Puma Biotechnology Reports Inducement Award Under Nasdaq Listing Rule 5635(c)(4)
October 5, 2026  |  marketscreener.comM
Puma Biotechnology Initiates ALISCA(R)-Lung2, a Phase II Trial of Alisertib in Combination with Paclitaxel for the Treatment of Patients with Advanced Small Cell Lung Cancer
September 18, 2026  |  marketscreener.comM

New MarketBeat Followers Over Time

Media Sentiment Over Time

Amylyx Pharmaceuticals stock logo

Amylyx Pharmaceuticals NASDAQ:AMLX

$29.86 -1.94 (-6.10%)
Closing price 11/12/2026 04:00 PM Eastern
Extended Trading
$29.85 -0.01 (-0.03%)
As of 04:29 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Amylyx Pharmaceuticals, Inc is a biopharmaceutical company dedicated to developing treatments for rare and debilitating neurological diseases. Founded in 2013 and headquartered in Cambridge, Massachusetts, the company focuses on leveraging novel approaches to target cellular pathways implicated in neurodegeneration. Amylyx's research platform centers on small-molecule therapies designed to protect neurons and support cellular health in patients with conditions that currently have limited or no disease-modifying treatment options.

Puma Biotechnology stock logo

Puma Biotechnology NASDAQ:PBYI

$8.08 0.00 (0.00%)
Closing price 11/12/2026 04:00 PM Eastern
Extended Trading
$8.11 +0.03 (+0.36%)
As of 04:05 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. The company offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. It also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. The company sells its products through specialty pharmacy and distributor networks. It has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds; and Takeda Pharmaceutical Company Limited for the research, development, and commercialization of alisertib, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. The company was founded in 2010 and is headquartered in Los Angeles, California.

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