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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ACAD NASDAQ:ARWR NASDAQ:ASND NASDAQ:IONS NASDAQ:UTHR On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeACADACADIA Pharmaceuticals$21.09$21.76$19.69▼$28.35$3.61B0.841.19 million shs753,933 shsARWRArrowhead Pharmaceuticals$74.52$72.46$14.30▼$82.26$10.50B1.281.42 million shs1.18 million shsASNDAscendis Pharma A/S$218.06$232.15$160.86▼$250.74$13.60B0.39543,380 shs405,008 shsIONSIonis Pharmaceuticals$73.28$74.94$34.78▼$86.74$12.11B0.371.63 million shs1.96 million shsUTHRUnited Therapeutics$545.96$566.75$272.12▼$609.35$23.18B0.57449,246 shs451,821 shs7 Stocks to Buy And Hold ForeverClick the link to see MarketBeat's list of seven stocks and why their long-term outlooks are very promising. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceACADACADIA Pharmaceuticals0.00%-2.18%-1.45%-1.40%-2.86%ARWRArrowhead Pharmaceuticals0.00%+1.96%-2.80%+29.89%+373.44%ASNDAscendis Pharma A/S0.00%+3.62%-9.33%-5.61%+27.67%IONSIonis Pharmaceuticals0.00%-1.61%-1.28%+1.30%+105.90%UTHRUnited Therapeutics0.00%-0.71%-3.98%+2.18%+92.68%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeACADACADIA Pharmaceuticals$21.09$21.76$19.69▼$28.35$3.61B0.841.19 million shs753,933 shsARWRArrowhead Pharmaceuticals$74.52$72.46$14.30▼$82.26$10.50B1.281.42 million shs1.18 million shsASNDAscendis Pharma A/S$218.06$232.15$160.86▼$250.74$13.60B0.39543,380 shs405,008 shsIONSIonis Pharmaceuticals$73.28$74.94$34.78▼$86.74$12.11B0.371.63 million shs1.96 million shsUTHRUnited Therapeutics$545.96$566.75$272.12▼$609.35$23.18B0.57449,246 shs451,821 shs7 Stocks to Buy And Hold ForeverClick the link to see MarketBeat's list of seven stocks and why their long-term outlooks are very promising. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceACADACADIA Pharmaceuticals0.00%-2.18%-1.45%-1.40%-2.86%ARWRArrowhead Pharmaceuticals0.00%+1.96%-2.80%+29.89%+373.44%ASNDAscendis Pharma A/S0.00%+3.62%-9.33%-5.61%+27.67%IONSIonis Pharmaceuticals0.00%-1.61%-1.28%+1.30%+105.90%UTHRUnited Therapeutics0.00%-0.71%-3.98%+2.18%+92.68%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceACADACADIA Pharmaceuticals 2.67Moderate Buy$31.6349.95% UpsideARWRArrowhead Pharmaceuticals 2.75Moderate Buy$87.8017.82% UpsideASNDAscendis Pharma A/S 3.00Buy$295.3935.46% UpsideIONSIonis Pharmaceuticals 2.90Moderate Buy$100.9037.69% UpsideUTHRUnited Therapeutics 2.85Moderate Buy$619.4213.45% UpsideCurrent Analyst Ratings BreakdownLatest ASND, ARWR, IONS, ACAD, and UTHR Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails6/9/2026ASNDAscendis Pharma A/S OppenheimerSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingOutperform5/27/2026IONSIonis Pharmaceuticals HC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$125.005/21/2026UTHRUnited Therapeutics TD CowenSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy5/20/2026ARWRArrowhead Pharmaceuticals Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingDowngradeHold (C-) ➝ Sell (D-)5/18/2026ASNDAscendis Pharma A/S CitigroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageBuy$355.005/18/2026IONSIonis Pharmaceuticals CitigroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageBuy$115.005/18/2026ASNDAscendis Pharma A/S CitigroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeBuy ➝ Strong-Buy5/18/2026IONSIonis Pharmaceuticals CitigroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeBuy ➝ Strong-Buy5/15/2026ASNDAscendis Pharma A/S EvercoreSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingOutperform$329.005/13/2026ARWRArrowhead Pharmaceuticals Sanford C. BernsteinSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetMarket Perform$35.00 ➝ $46.005/11/2026ASNDAscendis Pharma A/S BarclaysSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetOverweight$342.00 ➝ $345.00(Data available from 6/15/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookACADACADIA Pharmaceuticals$1.07B3.37$0.89 per share23.77$7.25 per share2.91ARWRArrowhead Pharmaceuticals$829.45M12.66$0.12 per share624.12$3.64 per share20.47ASNDAscendis Pharma A/S$814.57M16.70N/AN/A($2.97) per share-73.42IONSIonis Pharmaceuticals$944M12.83N/AN/A$3.02 per share24.26UTHRUnited Therapeutics$3.18B7.28$32.99 per share16.55$164.81 per share3.31Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateACADACADIA Pharmaceuticals$391M$2.209.5926.7026.4834.30%9.61%7.07%8/5/2026 (Estimated)ARWRArrowhead Pharmaceuticals-$1.63M-$2.15N/AN/AN/A-48.38%-55.09%-18.13%8/6/2026 (Estimated)ASNDAscendis Pharma A/S-$258M$8.6725.1520.30N/A57.87%N/A-8.37%8/6/2026 (Estimated)IONSIonis Pharmaceuticals-$381.39M-$2.07N/AN/AN/A-30.91%-58.65%-10.07%8/5/2026 (Estimated)UTHRUnited Therapeutics$1.33B$27.0920.1517.561.7840.62%19.24%17.25%7/29/2026 (Estimated)Latest ASND, ARWR, IONS, ACAD, and UTHR EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/7/2026Q2 2026ARWRArrowhead Pharmaceuticals-$1.0950-$0.93+$0.1650-$0.93$73.84 million$73.74 million5/7/2026Q1 2026ASNDAscendis Pharma A/S$0.21$0.32+$0.11$11.29$362.47 million$285.45 million5/6/2026Q1 2026ACADACADIA Pharmaceuticals$0.04$0.02-$0.02$0.02$280.25 million$268.10 million5/6/2026Q1 2026UTHRUnited Therapeutics$7.00$5.82-$1.18$5.82$797.40 million$781.50 million4/29/2026Q1 2026IONSIonis Pharmaceuticals-$0.85-$0.56+$0.29-$0.56$195.57 million$246.09 millionCompare DividendsCompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive GrowthACADACADIA PharmaceuticalsN/AN/AN/AN/AN/AARWRArrowhead PharmaceuticalsN/AN/AN/AN/AN/AASNDAscendis Pharma A/SN/AN/AN/AN/AN/AIONSIonis PharmaceuticalsN/AN/AN/AN/AN/AUTHRUnited TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioACADACADIA PharmaceuticalsN/A3.593.48ARWRArrowhead Pharmaceuticals1.416.236.23ASNDAscendis Pharma A/S0.791.000.72IONSIonis Pharmaceuticals2.754.104.09UTHRUnited TherapeuticsN/A4.794.50Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipACADACADIA Pharmaceuticals96.71%ARWRArrowhead Pharmaceuticals62.61%ASNDAscendis Pharma A/SN/AIONSIonis Pharmaceuticals93.86%UTHRUnited Therapeutics94.08%Insider OwnershipCompanyInsider OwnershipACADACADIA Pharmaceuticals26.20%ARWRArrowhead Pharmaceuticals3.60%ASNDAscendis Pharma A/S40.00%IONSIonis Pharmaceuticals1.81%UTHRUnited Therapeutics8.60%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableACADACADIA Pharmaceuticals510171.24 million126.37 millionOptionableARWRArrowhead Pharmaceuticals400140.86 million135.79 millionOptionableASNDAscendis Pharma A/S1,18962.38 million37.43 millionOptionableIONSIonis Pharmaceuticals1,402165.26 million162.27 millionOptionableUTHRUnited Therapeutics1,40042.45 million38.80 millionOptionableASND, ARWR, IONS, ACAD, and UTHR HeadlinesRecent News About These CompaniesNicholas Investment Partners LP Increases Stake in United Therapeutics Corporation $UTHRJune 14 at 7:02 AM | marketbeat.comEventide Asset Management LLC Cuts Stock Holdings in United Therapeutics Corporation $UTHRJune 14 at 4:56 AM | marketbeat.comUnited Therapeutics Corporation $UTHR Position Lowered by Epoch Investment Partners Inc.June 14 at 4:47 AM | marketbeat.comUnited Therapeutics Corporation $UTHR Shares Sold by Aurora Investment CounselJune 14 at 4:22 AM | marketbeat.comInsider Selling: United Therapeutics (NASDAQ:UTHR) CEO Sells $5,185,385.00 in StockJune 14 at 4:16 AM | americanbankingnews.comUnited Therapeutics (NASDAQ:UTHR) CFO Sells $5,492,900.00 in StockJune 12 at 7:02 PM | marketbeat.comMartine Rothblatt Sells 9,500 Shares of United Therapeutics (NASDAQ:UTHR) StockJune 12 at 6:24 AM | insidertrades.comFox Run Management L.L.C. Invests $1.28 Million in United Therapeutics Corporation $UTHRJune 10, 2026 | marketbeat.comUnited Therapeutics (NASDAQ:UTHR) CFO Sells $5,475,000.00 in StockJune 9, 2026 | marketbeat.comThese 3 Stocks Lowered Their Share Counts Drastically in Q1 (UTHR)...June 9, 2026 | marketbeat.comUnited Therapeutics Corporation $UTHR Shares Sold by Prudential PLCJune 9, 2026 | marketbeat.comUnited Therapeutics (NASDAQ:UTHR) CEO Sells $5,202,390.00 in StockJune 9, 2026 | insidertrades.comDaiwa Securities Group Inc. Raises Holdings in United Therapeutics Corporation $UTHRJune 9, 2026 | marketbeat.comBrandywine Global Investment Management LLC Has $14.55 Million Position in United Therapeutics Corporation $UTHRJune 9, 2026 | marketbeat.comUnited Therapeutics Corporation $UTHR Shares Sold by BI Asset Management Fondsmaeglerselskab A SJune 8, 2026 | marketbeat.comUnited Therapeutics Corporation (NASDAQ:UTHR) Given Consensus Recommendation of "Moderate Buy" by AnalystsJune 8, 2026 | americanbankingnews.com4,493 Shares in United Therapeutics Corporation $UTHR Purchased by Havemeyer Place LPJune 7, 2026 | marketbeat.comInsider Selling: United Therapeutics (NASDAQ:UTHR) EVP Sells $4,540,681.00 in StockJune 7, 2026 | americanbankingnews.comUnited Therapeutics (NASDAQ:UTHR) CFO Sells $5,462,800.00 in StockJune 6, 2026 | insidertrades.comUnited Therapeutics Corporation $UTHR Shares Sold by TD Asset Management IncJune 6, 2026 | marketbeat.comA Look At United Therapeutics (UTHR) Valuation After Strong Long Term Shareholder ReturnsJune 6, 2026 | finance.yahoo.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesQuantum Stocks Just Got a Lifeline—Who Benefits Most?By Nathan Reiff | May 26, 2026Is Everspin Technologies the Next AI Edge Breakout?By Thomas Hughes | May 18, 2026As Broadcom Eclipses $2 Trillion, Private Credit Giants Wants InBy Leo Miller | May 17, 2026These 3 CLO ETFs Target a Niche Corner of the Fixed-Income MarketBy Nathan Reiff | May 31, 2026As Small-Cap Outperformance Continues, These 2 ETFs Provide ExposureBy Jessica Mitacek | May 21, 2026ASND, ARWR, IONS, ACAD, and UTHR Company DescriptionsACADIA Pharmaceuticals NASDAQ:ACAD$21.09 0.00 (0.00%) Closing price 06/12/2026 04:00 PM EasternExtended Trading$21.30 +0.22 (+1.02%) As of 06/12/2026 06:06 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.ACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization innovative medicines that address unmet medical needs in central nervous system (CNS) disorders and rare diseases in the United States. The company offers NUPLAZID (pimavanserin) for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis; and DAYBUE, a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 for treatment of Rett Syndrome. It also develops Pimavanserin that is in Phase III ADVANCE-2 study to treat the negative symptoms of schizophrenia; ACP-101 whixh is in Phase III for the treatment of hyperphagia in Prader-Willi syndrome; ACP-204 which is in Phase II for the treatment of Alzheimer's disease psychosis; ACP-2591 that is in Phase I for Rett syndrome and Fragile X syndrome; preclinical antisense oligonucleotide programs; and other programs for neuropsychiatric symptoms. It has a license agreement with Neuren Pharmaceuticals Limited to develop and commercialize trofinetide for Rett syndrome and other indications; and a license and collaboration agreement with Stoke Therapeutics, Inc. to discover, develop and commercialize novel RNA-based medicines for the potential treatment of severe and rare genetic neurodevelopmental diseases of the CNS. The company was formerly known as Receptor Technologies, Inc. and changed its name ACADIA Pharmaceuticals Inc. in 1997. ACADIA Pharmaceuticals Inc. was incorporated in 1993 and is headquartered in San Diego, California.Arrowhead Pharmaceuticals NASDAQ:ARWR$74.52 0.00 (0.00%) Closing price 06/12/2026 04:00 PM EasternExtended Trading$75.14 +0.62 (+0.83%) As of 06/12/2026 06:35 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. The company's products in pipeline includes Plozasiran, which is in Phase 2b and one Phase 3 clinical trial to treat hypertriglyceridemia, mixed dyslipidemia, and chylomicronemia syndrome; Zodasiran that is in Phase 2b clinical trial for the treatment of dyslipidemia and hypertriglyceridemia; ARO-PNPLA3, which is in Phase 1 clinical trial to treat patients with non-alcoholic steatohepatitis; ARO-RAGE that is in Phase 1/2a clinical trial to treat inflammatory pulmonary conditions; and ARO-MUC5AC, which is in Phase 1/2a clinical trial to treat muco-obstructive pulmonary diseases. It also develops ARO-MMP7 that is in Phase 1/2a clinical trial for treatment of idiopathic pulmonary fibrosis; ARO-DUX4 for the treatment of facioscapulohumeral muscular dystrophy; ARO-SOD1 for the potential treatment of amyotrophic lateral sclerosis; and ARO-C3, which is in Phase 1/2a clinical trial for the treatment of patients with various complement mediated or complement associated renal diseases. In addition, the company is involved in the development of JNJ-3989, which is in Phase 2 clinical trial to treat chronic hepatitis B virus infection; Olpasiran that is in Phase 3 clinical trial to reduce the production of apolipoprotein A; GSK-4532990 that is in phase 2 clinical trial to treat liver diseases; HZN-457, which is in phase 1 clinical trial to treat uncontrolled gout; and Fazirsiran that is in Phase 3 clinical trial for the treatment for liver disease associated with alpha-1 antitrypsin deficiency. Arrowhead Pharmaceuticals, Inc. has license and research collaboration agreements with Janssen Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; Horizon Therapeutics Ireland DAC; Amgen Inc.; and Glaxosmithkline Intellectual Property (No. 3) Limited. The company was founded in 2003 and is headquartered in Pasadena, California.Ascendis Pharma A/S NASDAQ:ASND$218.06 0.00 (0.00%) Closing price 06/12/2026 04:00 PM EasternExtended Trading$218.30 +0.24 (+0.11%) As of 06/12/2026 07:42 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Ascendis Pharma A/S, a biopharmaceutical company, focuses on developing therapies for unmet medical needs. It offers SKYTROFA for treating patients with growth hormone deficiency (GHD). The company is also developing a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. The company was incorporated in 2006 and is headquartered in Hellerup, Denmark.Ionis Pharmaceuticals NASDAQ:IONS$73.28 0.00 (0.00%) Closing price 06/12/2026 04:00 PM EasternExtended Trading$73.53 +0.25 (+0.34%) As of 06/12/2026 07:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.United Therapeutics NASDAQ:UTHR$545.96 0.00 (0.00%) Closing price 06/12/2026 04:00 PM EasternExtended Trading$543.46 -2.50 (-0.46%) As of 06/12/2026 07:58 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.United Therapeutics Corporation, a biotechnology company, engages in the development and commercialization of products to address the unmet medical needs of patients with chronic and life-threatening diseases in the United States and internationally. The company offers Tyvaso DPI, an inhaled dry powder via pre-filled and single-use cartridges; Tyvaso, an inhaled solution via ultrasonic nebulizer; Remodulin (treprostinil) injection to treat patients with pulmonary arterial hypertension (PAH) to diminish symptoms associated with exercise; Orenitram, a tablet dosage form of treprostinil, to delay disease progression and improve exercise capacity in PAH patients; and Adcirca, an oral PDE-5 inhibitor to enhance the exercise ability in PAH patients. It also markets and sells Unituxin (dinutuximab) injection, a monoclonal antibody for treating high-risk neuroblastoma; and Remunity Pump, which contains a pump and separate controller for Remodulin. In addition, the company engages in developing RemoPro and Ralinepag for the treatment of PAH; Aurora-GT, a gene therapy product to rebuild the blood vessels in the lungs; and Nebulized Tyvaso, for the treatment of idiopathic pulmonary fibrosis, as well as xenografts, which are development-stage organ products. It has licensing and collaboration agreements with DEKA Research & Development Corp. to develop a semi-disposable system for the subcutaneous delivery of treprostinil; MannKind Corporation to develop and license treprostinil inhalation powder and the Dreamboat device; and Arena Pharmaceuticals, Inc. to develop Ralinepag. The company was incorporated in 1996 and is headquartered in Silver Spring, Maryland. 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