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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:CRSP NASDAQ:EDIT NASDAQ:NTLA NYSE:NVS NASDAQ:REGN NASDAQ:VRTX On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCRSPCRISPR Therapeutics$61.19+5.8%$56.99$30.04▼$71.13$5.26B1.811.71 million shs4.62 million shsEDITEditas Medicine$2.83+6.0%$2.74$0.91▼$4.12$240.09M2.161.14 million shs2.57 million shsNTLAIntellia Therapeutics$12.27+6.1%$11.67$5.90▼$23.76$1.24B2.283.85 million shs7.09 million shsNVSNovartis$122.89-0.3%$121.76$96.06▼$130.46$260.48B0.631.03 million shs954,753 shsREGNRegeneron Pharmaceuticals$575.06+0.4%$565.85$476.49▼$1,165.85$60.69B0.35928,174 shs707,913 shsVRTXVertex Pharmaceuticals$391.36-0.5%$419.84$362.50▼$519.88$100.82B0.441.37 million shs1.70 million shsThe Next 7 Blockbuster Stocks for Growth InvestorsWondering what the next stocks will be that hit it big, with solid fundamentals? Enter your email address to see which stocks MarketBeat analysts could become the next blockbuster growth stocks.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCRSPCRISPR Therapeutics+5.79%+13.97%+2.44%+37.72%+28.17%EDITEditas Medicine+5.99%+2.54%-6.60%+20.43%-26.11%NTLAIntellia Therapeutics+6.05%+3.28%+11.65%+27.81%-42.96%NVSNovartis-0.31%-4.10%-1.05%+5.97%+5.08%REGNRegeneron Pharmaceuticals+0.43%+3.33%-0.92%+11.97%-50.13%VRTXVertex Pharmaceuticals-0.47%-1.29%-0.36%-12.72%-20.04%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCRSPCRISPR Therapeutics$61.19+5.8%$56.99$30.04▼$71.13$5.26B1.811.71 million shs4.62 million shsEDITEditas Medicine$2.83+6.0%$2.74$0.91▼$4.12$240.09M2.161.14 million shs2.57 million shsNTLAIntellia Therapeutics$12.27+6.1%$11.67$5.90▼$23.76$1.24B2.283.85 million shs7.09 million shsNVSNovartis$122.89-0.3%$121.76$96.06▼$130.46$260.48B0.631.03 million shs954,753 shsREGNRegeneron Pharmaceuticals$575.06+0.4%$565.85$476.49▼$1,165.85$60.69B0.35928,174 shs707,913 shsVRTXVertex Pharmaceuticals$391.36-0.5%$419.84$362.50▼$519.88$100.82B0.441.37 million shs1.70 million shsThe Next 7 Blockbuster Stocks for Growth InvestorsWondering what the next stocks will be that hit it big, with solid fundamentals? Enter your email address to see which stocks MarketBeat analysts could become the next blockbuster growth stocks.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCRSPCRISPR Therapeutics+5.79%+13.97%+2.44%+37.72%+28.17%EDITEditas Medicine+5.99%+2.54%-6.60%+20.43%-26.11%NTLAIntellia Therapeutics+6.05%+3.28%+11.65%+27.81%-42.96%NVSNovartis-0.31%-4.10%-1.05%+5.97%+5.08%REGNRegeneron Pharmaceuticals+0.43%+3.33%-0.92%+11.97%-50.13%VRTXVertex Pharmaceuticals-0.47%-1.29%-0.36%-12.72%-20.04%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceCRSPCRISPR Therapeutics 2.47Hold$71.6017.01% UpsideEDITEditas Medicine 2.23Hold$5.1080.21% UpsideNTLAIntellia Therapeutics 2.56Moderate Buy$27.11120.95% UpsideNVSNovartis 2.00Hold$120.33-2.08% DownsideREGNRegeneron Pharmaceuticals 2.82Moderate Buy$817.6742.19% UpsideVRTXVertex Pharmaceuticals 2.57Moderate Buy$496.0526.75% UpsideCurrent Analyst Ratings BreakdownLatest EDIT, NTLA, VRTX, CRSP, NVS, and REGN Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails9/12/2025NVSNovartisThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingNeutral ➝ Sell$119.00 ➝ $118.009/11/2025VRTXVertex PharmaceuticalsEvercore ISISubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetOutperform$510.00 ➝ $475.009/5/2025EDITEditas MedicineHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$5.009/3/2025EDITEditas MedicineWells Fargo & CompanySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetEqual Weight$3.00 ➝ $4.009/2/2025VRTXVertex PharmaceuticalsRaymond James FinancialSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageMarket Perform9/2/2025REGNRegeneron PharmaceuticalsRaymond James FinancialSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeModerate Buy8/27/2025REGNRegeneron PharmaceuticalsSanford C. BernsteinSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetOutperform$753.00 ➝ $781.008/27/2025REGNRegeneron PharmaceuticalsJefferies Financial GroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetBuy$813.00 ➝ $831.008/26/2025CRSPCRISPR TherapeuticsZacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeStrong Sell ➝ Hold8/21/2025NVSNovartisDeutsche Bank AktiengesellschaftSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy8/15/2025EDITEditas MedicineHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetBuy$3.00 ➝ $5.00(Data available from 9/17/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookCRSPCRISPR Therapeutics$37.31M149.16N/AN/A$22.64 per share2.70EDITEditas Medicine$32.31M7.88N/AN/A$1.63 per share1.74NTLAIntellia Therapeutics$57.88M22.76N/AN/A$8.56 per share1.43NVSNovartis$50.32B5.16$10.67 per share11.52$21.59 per share5.69REGNRegeneron Pharmaceuticals$14.20B4.29$45.89 per share12.53$268.50 per share2.14VRTXVertex Pharmaceuticals$11.02B9.11N/AN/A$63.72 per share6.14Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateCRSPCRISPR Therapeutics-$366.25M-$5.43N/AN/AN/A-1,229.43%-20.05%-17.09%11/4/2025 (Estimated)EDITEditas Medicine-$237.09M-$2.85N/AN/AN/A-608.88%-200.25%-68.57%11/3/2025 (Estimated)NTLAIntellia Therapeutics-$519.02M-$4.69N/AN/AN/A-908.48%-57.48%-45.04%11/6/2025 (Estimated)NVSNovartis$11.94B$6.8717.8913.951.7225.64%41.08%16.83%11/4/2025 (Estimated)REGNRegeneron Pharmaceuticals$4.41B$39.6814.4915.131.9231.37%15.06%11.77%10/30/2025 (Estimated)VRTXVertex Pharmaceuticals-$535.60M$13.9927.9722.35N/A31.86%23.91%17.14%11/3/2025 (Estimated)Latest EDIT, NTLA, VRTX, CRSP, NVS, and REGN EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/12/2025Q2 2025EDITEditas Medicine-$0.41-$0.63-$0.22-$0.63$1.81 million$3.58 million8/7/2025Q2 2025NTLAIntellia Therapeutics-$1.03-$0.99+$0.04-$0.98$12.26 million$14.25 million8/4/2025Q2 2025CRSPCRISPR Therapeutics-$1.47-$1.29+$0.18-$2.40$6.44 million$0.89 million8/4/2025Q2 2025VRTXVertex Pharmaceuticals$4.24$4.52+$0.28$3.99$2.90 billion$2.94 billion8/1/2025Q2 2025REGNRegeneron Pharmaceuticals$8.43$12.89+$4.46$12.81$3.30 billion$3.68 billion7/17/2025Q2 2025NVSNovartis$2.38$2.42+$0.04$2.06$13.94 billion$14.05 billionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthCRSPCRISPR TherapeuticsN/AN/AN/AN/AN/AEDITEditas MedicineN/AN/AN/AN/AN/ANTLAIntellia TherapeuticsN/AN/AN/AN/AN/ANVSNovartis$2.602.12%N/A37.85%N/AREGNRegeneron Pharmaceuticals$3.520.61%N/A8.87%N/AVRTXVertex PharmaceuticalsN/AN/AN/AN/AN/ALatest EDIT, NTLA, VRTX, CRSP, NVS, and REGN DividendsAnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date8/1/2025REGNRegeneron Pharmaceuticalsquarterly$0.880.6%8/18/20258/18/20259/3/2025(Data available from 1/1/2013 forward)Compare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioCRSPCRISPR TherapeuticsN/A16.6116.61EDITEditas MedicineN/A2.772.77NTLAIntellia TherapeuticsN/A5.195.19NVSNovartis0.530.820.62REGNRegeneron Pharmaceuticals0.094.603.72VRTXVertex PharmaceuticalsN/A2.522.16Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipCRSPCRISPR Therapeutics69.20%EDITEditas Medicine71.90%NTLAIntellia Therapeutics88.77%NVSNovartis13.12%REGNRegeneron Pharmaceuticals83.31%VRTXVertex Pharmaceuticals90.96%Insider OwnershipCompanyInsider OwnershipCRSPCRISPR Therapeutics4.10%EDITEditas Medicine1.90%NTLAIntellia Therapeutics3.10%NVSNovartis0.01%REGNRegeneron Pharmaceuticals7.02%VRTXVertex Pharmaceuticals0.20%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableCRSPCRISPR Therapeutics46090.95 million87.22 millionOptionableEDITEditas Medicine23089.92 million88.21 millionOptionableNTLAIntellia Therapeutics600107.35 million104.02 millionOptionableNVSNovartis75,8832.11 billion2.11 billionOptionableREGNRegeneron Pharmaceuticals15,106105.99 million98.55 millionOptionableVRTXVertex Pharmaceuticals6,100256.39 million255.88 millionOptionableEDIT, NTLA, VRTX, CRSP, NVS, and REGN HeadlinesRecent News About These CompaniesNew England Research & Management Inc. Makes New Investment in Vertex Pharmaceuticals Incorporated $VRTX2 hours ago | marketbeat.comCzech National Bank Has $27.95 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX3 hours ago | marketbeat.comMassMutual Private Wealth & Trust FSB Raises Stock Position in Vertex Pharmaceuticals Incorporated $VRTX4 hours ago | marketbeat.comWhy This Biotech Company Could Be a Growth Stock Powerhouse4 hours ago | fool.comPaladin Wealth LLC Purchases Shares of 1,240 Vertex Pharmaceuticals Incorporated $VRTXSeptember 16 at 6:08 AM | marketbeat.comGradient Investments LLC Buys New Shares in Vertex Pharmaceuticals Incorporated $VRTXSeptember 16 at 5:30 AM | marketbeat.comE. Ohman J or Asset Management AB Has $4.68 Million Stock Position in Vertex Pharmaceuticals Incorporated $VRTXSeptember 16 at 5:30 AM | marketbeat.comGK Wealth Management LLC Purchases Shares of 689 Vertex Pharmaceuticals Incorporated $VRTXSeptember 16 at 5:20 AM | marketbeat.comModern Wealth Management LLC Purchases New Position in Vertex Pharmaceuticals Incorporated $VRTXSeptember 16 at 3:50 AM | marketbeat.com1 Reason Wall Street Is Obsessed With Vertex PharmaceuticalsSeptember 15 at 8:30 AM | fool.comVertex Pharmaceuticals: Strong Buy Rating Backed by Promising Pipeline and Strategic PositioningSeptember 15 at 7:31 AM | tipranks.comVertex Pharmaceuticals Incorporated $VRTX Shares Sold by Cim LLCSeptember 15 at 5:18 AM | marketbeat.comAdvisors Capital Management LLC Trims Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTXSeptember 15 at 4:47 AM | marketbeat.comIntech Investment Management LLC Has $4.22 Million Stake in Vertex Pharmaceuticals Incorporated $VRTXSeptember 15 at 4:31 AM | marketbeat.comIntegrity Alliance LLC. Makes New $445,000 Investment in Vertex Pharmaceuticals Incorporated $VRTXSeptember 15 at 4:20 AM | marketbeat.com9,601 Shares in Vertex Pharmaceuticals Incorporated $VRTX Purchased by AG2R LA Mondiale Gestion D ActifsSeptember 14 at 7:02 AM | marketbeat.comSwedbank AB Decreases Position in Vertex Pharmaceuticals Incorporated $VRTXSeptember 14 at 6:52 AM | marketbeat.comVoya Investment Management LLC Acquires 128,432 Shares of Vertex Pharmaceuticals Incorporated $VRTXSeptember 14 at 6:51 AM | marketbeat.comStrs Ohio Invests $37.74 Million in Vertex Pharmaceuticals Incorporated $VRTXSeptember 14 at 5:16 AM | marketbeat.comVertex Pharmaceuticals Incorporated $VRTX Shares Sold by McAdam LLCSeptember 14 at 4:57 AM | marketbeat.comEvercore ISI Cuts Vertex Pharmaceuticals (NASDAQ:VRTX) Price Target to $475.00September 13, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesBuffett Makes Big Moves Outside of UNH: A Buy and Sell BreakdownBy Leo Miller | August 18, 20253 Robotics Stocks at the Heart of the Robotics RevolutionBy Chris Markoch | August 21, 2025NIO Just Got Its Second Upgrade of the Month, and It’s BigBy Sam Quirke | August 28, 20255 High Short-Interest Stocks to Buy Before NovemberBy Thomas Hughes | August 20, 2025Novartis' Moonshot Cancer Therapy Could Be Future Growth DriverBy Chris Markoch | September 9, 2025EDIT, NTLA, VRTX, CRSP, NVS, and REGN Company DescriptionsCRISPR Therapeutics NASDAQ:CRSP$61.19 +3.35 (+5.79%) Closing price 09/16/2025 04:00 PM EasternExtended Trading$61.44 +0.26 (+0.42%) As of 08:23 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.CRISPR Therapeutics is a gene-editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom. For more information, please visit www.crisprtx.com.Editas Medicine NASDAQ:EDIT$2.83 +0.16 (+5.99%) Closing price 09/16/2025 04:00 PM EasternExtended Trading$2.84 +0.02 (+0.53%) As of 08:22 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Editas Medicine, Inc., a clinical stage genome editing company, focuses on developing transformative genomic medicines to treat a range of serious diseases. It develops a proprietary gene editing platform based on CRISPR technology. The company develops EDIT-101, which is in Phase 1/2 BRILLIANCE trial for Leber Congenital Amaurosis; and reni-cel, a clinical development gene-edited medicine to treat sickle cell disease and transfusion-dependent beta-thalassemia. In addition, the company is developing alpha-beta T cells for solid and liquid tumors; and gamma delta T cell therapies to treat cancer. It has a research collaboration with Juno Therapeutics, Inc. to develop engineered T cells for cancer; strategic alliance and option agreement with Allergan Pharmaceuticals International Limited. The company was formerly known as Gengine, Inc. and changed its name to Editas Medicine, Inc. in November 2013. Editas Medicine, Inc. was incorporated in 2013 and is based in Cambridge, Massachusetts.Intellia Therapeutics NASDAQ:NTLA$12.27 +0.70 (+6.05%) Closing price 09/16/2025 04:00 PM EasternExtended Trading$13.04 +0.77 (+6.28%) As of 08:23 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Intellia Therapeutics, Inc., a genome editing company, focuses on the development of curative therapeutics. The company's in vivo programs include NTLA-2001, which is in Phase 1 clinical trial for the treatment of transthyretin amyloidosis; NTLA-2002 for the treatment of hereditary angioedema; and NTLA-3001 for alpha-1 antitrypsin deficiency associated lung disease. It also focusses on programs comprising hemophilia A and hemophilia B; and research of proprietary programs focused on developing engineered cell therapies to treat various cancers and autoimmune diseases. In addition, the company offers tools comprising of Clustered, Regularly Interspaced Short Palindromic Repeats/CRISPR associated 9 (CRISPR/Cas9) system. It has license and collaboration agreement with Regeneron Pharmaceuticals, Inc. to co-develop potential products for the treatment of hemophilia A and hemophilia B; AvenCell Therapeutics, Inc. to develop allogeneic universal CAR-T cell therapies, and co-develop and co-commercialize allogeneic universal CAR-T cell products for an immuno-oncology indication; SparingVision SAS to develop novel genomic medicines utilizing CRISPR/Cas9 technology for the treatment of ocular diseases; Kyverna Therapeutics, Inc. for the development of an allogeneic CD19 CAR-T cell therapy for the treatment of a variety of B cell-mediated autoimmune diseases; and ONK Therapeutics, Ltd. for the development of engineered NK cell therapies to cure patients with cancer. Intellia Therapeutics, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.Novartis NYSE:NVS$122.89 -0.42 (-0.34%) Closing price 09/16/2025 03:59 PM EasternExtended Trading$122.27 -0.62 (-0.50%) As of 08:16 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Novartis AG engages in the research, development, manufacture, and marketing of healthcare products in Switzerland and internationally. The company offers prescription medicines for patients and physicians. It focuses on therapeutic areas, such as cardiovascular, renal and metabolic, immunology, neuroscience, and oncology, as well as ophthalmology and hematology. Novartis AG has a license and collaboration agreement with Alnylam Pharmaceuticals to develop, manufacture, and commercialize inclisiran, a therapy to reduce LDL cholesterol; and Dawn Health for the development and commercialization of Ekiva, a digital solution designed for people living with Paroxysmal Nocturnal Hemoglobinuria. The company was incorporated in 1996 and is headquartered in Basel, Switzerland.Regeneron Pharmaceuticals NASDAQ:REGN$575.06 +2.47 (+0.43%) Closing price 09/16/2025 04:00 PM EasternExtended Trading$578.25 +3.19 (+0.55%) As of 08:16 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various diseases worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular edema; myopic choroidal neovascularization; diabetic retinopathy; neovascular glaucoma; and retinopathy of prematurity. It also provides Dupixent injection to treat atopic dermatitis and asthma in adults and pediatrics; Libtayo injection to treat metastatic or locally advanced cutaneous squamous cell carcinoma; Praluent injection for heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in adults; REGEN-COV for covid-19; and Kevzara solution for treating rheumatoid arthritis in adults. In addition, the company offers Inmazeb injection for infection caused by Zaire ebolavirus; ARCALYST injection for cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome and muckle-wells syndrome; and ZALTRAP injection for intravenous infusion to treat metastatic colorectal cancer; and develops product candidates for treating patients with eye, allergic and inflammatory, cardiovascular and metabolic, infectious, and rare diseases; and cancer, pain, and hematologic conditions. It has collaboration with Mammoth Biosciences, Inc. to research, develop and commercialize in vivo CRISPR-based gene editing therapies for multiple tissues and cell types. The company was incorporated in 1988 and is headquartered in Tarrytown, New York.Vertex Pharmaceuticals NASDAQ:VRTX$391.36 -1.85 (-0.47%) Closing price 09/16/2025 04:00 PM EasternExtended Trading$391.16 -0.21 (-0.05%) As of 08:07 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts. 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