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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
$7.99
+0.8%
$6.19
$4.35
$9.27
$581.03M-0.592.22 million shs1.59 million shs
Climb Bio, Inc. stock logo
CLYM
Climb Bio
$11.00
+0.8%
$8.70
$1.16
$12.48
$624.71M0.02945,215 shs454,122 shs
EIKN
EIKN
$10.91
-2.2%
$10.66
$7.90
$17.40
$590.66MN/A364,343 shs223,696 shs
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
$2.76
+2.6%
$2.58
$0.66
$3.22
$159.81M1.43554,244 shs545,468 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
+0.76%-8.89%+8.86%+56.36%+46.07%
Climb Bio, Inc. stock logo
CLYM
Climb Bio
+0.82%+1.85%+18.28%+95.38%+809.09%
EIKN
EIKN
-2.24%-17.66%-5.95%-26.68%+1,090,999,900.00%
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
+2.60%-1.08%-3.50%+20.00%+302.45%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
$7.99
+0.8%
$6.19
$4.35
$9.27
$581.03M-0.592.22 million shs1.59 million shs
Climb Bio, Inc. stock logo
CLYM
Climb Bio
$11.00
+0.8%
$8.70
$1.16
$12.48
$624.71M0.02945,215 shs454,122 shs
EIKN
EIKN
$10.91
-2.2%
$10.66
$7.90
$17.40
$590.66MN/A364,343 shs223,696 shs
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
$2.76
+2.6%
$2.58
$0.66
$3.22
$159.81M1.43554,244 shs545,468 shs
A Guide To High-Short-Interest Stocks Cover

MarketBeat's analysts have just released their top five short plays for June 2026. Learn which stocks have the most short interest and how to trade them. Click the link to see which companies made the list.

Get This Free Report

Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
+0.76%-8.89%+8.86%+56.36%+46.07%
Climb Bio, Inc. stock logo
CLYM
Climb Bio
+0.82%+1.85%+18.28%+95.38%+809.09%
EIKN
EIKN
-2.24%-17.66%-5.95%-26.68%+1,090,999,900.00%
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
+2.60%-1.08%-3.50%+20.00%+302.45%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
2.56
Moderate Buy$18.00125.28% Upside
Climb Bio, Inc. stock logo
CLYM
Climb Bio
3.08
Buy$20.3084.55% Upside
EIKN
EIKN
2.57
Moderate Buy$25.20130.98% Upside
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
1.50
ReduceN/AN/A

Current Analyst Ratings Breakdown

Latest SPRO, EIKN, CADL, and CLYM Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
5/15/2026
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
UpgradeStrong SellHold
5/12/2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
Boost Price TargetBuy$15.00 ➝ $20.00
5/12/2026
EIKN
EIKN
Lower Price TargetUnderperform$7.00 ➝ $5.00
5/8/2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
Boost Price TargetOutperform$15.00 ➝ $17.00
5/6/2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
Set Price Target$21.00
5/6/2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
Boost Price TargetBuy$8.00 ➝ $19.00
5/5/2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
Initiated CoverageBuy$22.00
4/21/2026
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
Reiterated RatingSell (D-)
4/21/2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
Boost Price TargetOutperform$10.00 ➝ $18.00
4/20/2026
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
Reiterated RatingSell (D-)
4/20/2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
Reiterated RatingSell (D-)
(Data available from 5/23/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
N/AN/AN/AN/A$1.88 per shareN/A
Climb Bio, Inc. stock logo
CLYM
Climb Bio
N/AN/AN/AN/A$2.59 per shareN/A
EIKN
EIKN
N/AN/AN/AN/AN/AN/A
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
$54.77M2.92$0.16 per share17.68$0.91 per share3.03
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
-$38.18M-$0.98N/AN/AN/AN/A-60.42%-41.33%N/A
Climb Bio, Inc. stock logo
CLYM
Climb Bio
-$59.85M-$0.78N/AN/AN/AN/A-31.45%-30.39%8/11/2026 (Estimated)
EIKN
EIKN
N/AN/AN/AN/AN/AN/AN/AN/AN/A
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
$8.57M$0.2411.50N/AN/A24.90%35.58%24.95%8/11/2026 (Estimated)

Latest SPRO, EIKN, CADL, and CLYM Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/14/2026Q1 2026
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
-$0.2958-$0.14+$0.1558-$0.14N/AN/A
5/13/2026Q1 2026
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
-$0.18-$0.13+$0.05-$0.13$0.26 million$0.26 million
5/11/2026Q1 2026
EIKN
EIKN
-$1.47-$2.46-$0.99-$2.46N/AN/A
5/7/2026Q1 2026
Climb Bio, Inc. stock logo
CLYM
Climb Bio
-$0.26-$0.20+$0.06-$0.20N/AN/A
3/30/2026Q4 2025
EIKN
EIKN
N/A-$26.23N/A-$26.23N/AN/A
3/26/2026Q4 2025
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
-$0.20$0.53+$0.73$0.53$26.00 million$41.30 million
3/12/2026Q4 2025
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
-$0.24-$0.54-$0.30-$0.54N/AN/A
3/5/2026Q4 2025
Climb Bio, Inc. stock logo
CLYM
Climb Bio
-$0.20-$0.26-$0.06-$0.26N/AN/A
CompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive Growth
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
N/AN/AN/AN/AN/A
Climb Bio, Inc. stock logo
CLYM
Climb Bio
N/AN/AN/AN/AN/A
EIKN
EIKN
N/AN/AN/AN/AN/A
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
$0.062.17%N/A25.00%N/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
0.34
28.05
28.05
Climb Bio, Inc. stock logo
CLYM
Climb Bio
N/A
27.86
27.86
EIKN
EIKN
N/AN/AN/A
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
N/A
10.50
10.50

Institutional Ownership

CompanyInstitutional Ownership
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
13.93%
Climb Bio, Inc. stock logo
CLYM
Climb Bio
69.76%
EIKN
EIKN
N/A
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
25.60%

Insider Ownership

CompanyInsider Ownership
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
14.30%
Climb Bio, Inc. stock logo
CLYM
Climb Bio
2.60%
EIKN
EIKN
N/A
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
5.50%
CompanyEmployeesShares OutstandingFree FloatOptionable
Candel Therapeutics, Inc. stock logo
CADL
Candel Therapeutics
6073.27 million62.79 millionOptionable
Climb Bio, Inc. stock logo
CLYM
Climb Bio
957.26 million55.77 millionN/A
EIKN
EIKN
38454.14 millionN/AN/A
Spero Therapeutics, Inc. stock logo
SPRO
Spero Therapeutics
15057.90 million54.72 millionOptionable

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Candel Therapeutics stock logo

Candel Therapeutics NASDAQ:CADL

$7.99 +0.06 (+0.76%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$8.03 +0.04 (+0.50%)
As of 05/22/2026 07:39 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Candel Therapeutics, Inc., a clinical stage biopharmaceutical company, engages in the development immunotherapies for the cancer patients. It develops CAN-2409, which is in Phase II clinical trials for the treatment of pancreatic cancer; Phase III clinical trials for the treatment of prostate cancer; and Phase II clinical trials for the treatment of lung cancer, as well as has completed Phase Ib/II clinical trials for the treatment of high-grade glioma. The company also develops CAN-3110, which is in Phase I clinical trials for the treatment of recurrent high-grade glioma. It also develops the?enLIGHTEN Discovery Platform, a systematic, iterative HSV-based discovery platform leveraging human biology and advanced analytics to create new viral immunotherapies for solid tumors. The company was formerly known as Advantagene, Inc. and changed its name to Candel Therapeutics, Inc. in November 2020. Candel Therapeutics, Inc. was incorporated in 2003 and is headquartered in Needham, Massachusetts.

Climb Bio stock logo

Climb Bio NASDAQ:CLYM

$11.00 +0.09 (+0.82%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$10.96 -0.04 (-0.36%)
As of 05/22/2026 07:17 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Climb Bio Inc. is a clinical-stage biotechnology company developing therapeutics for patients with immune-mediated diseases. The Company's lead product candidate, budoprutug, is an anti-CD19 monoclonal antibody which has demonstrated B-cell depletion and has potential to treat a broad range of B-cell mediated diseases. Climb Bio Inc., formerly known as Eliem Therapeutics Inc., is based in WELLESLEY, Mass.

EIKN NASDAQ:EIKN

$10.91 -0.25 (-2.24%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$10.91 0.00 (0.00%)
As of 05/22/2026 05:23 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

We are a late-stage clinical biopharmaceutical company dedicated to building a global, fully-integrated organization developing important, innovative medicines to address serious unmet medical needs. We are led by world-renowned drug developers Dr. Roger M. Perlmutter, M.D., Ph.D., and Dr. Roy Baynes, M.D., Ph.D. Our vision is to become a generational leader, by purposefully integrating traditional biology research with advanced engineering to develop better medicines faster. Our initial focus is oncology, where we are advancing a pipeline of drug candidates targeting areas of high unmet need in large indications. We believe our product candidates reflect strong scientific and clinical potential and could eventually become critical medicines in the treatment paradigm of various cancers. Our Chair and Chief Executive Officer, Dr. Roger M. Perlmutter, M.D., Ph.D., and our Chief Medical Officer, Dr. Roy Baynes, M.D., Ph.D., together have a proven track record of identifying, developing, and commercializing some of the most impactful drugs ever brought to market, including pembrolizumab, currently the world’s best-selling oncology therapeutic and arguably the most important anti-neoplastic agent ever introduced into clinical practice. While Drs. Perlmutter and Baynes’ track records do not provide a guarantee of future clinical success, and any products developed by us may not achieve the regulatory or commercial success of products that Drs. Perlmutter and Baynes were previously involved in developing, their experience provides valuable insight and strategic guidance to our drug development efforts. Our broader leadership team consists of former senior leaders at global pharmaceutical companies, who have successfully collaborated across several decades on the discovery, development, and commercialization of over 100 new molecular entities. Our strategy centers around deploying our technology platform, including our proprietary single molecule tracking, or SMT, system, to develop internally-derived novel therapies, while also leveraging the deep expertise of our management team to opportunistically in-license promising assets. Our most advanced product candidate, EIK1001, a toll-like receptor, or TLR, 7/8 dual-agonist, is currently in a global Phase 2/3 registrational trial in combination with pembrolizumab for the treatment of patients with advanced melanoma. This Phase 2/3 trial is designed to proceed to completion, subject to interim analysis by a data monitoring committee, and to form the basis for registration. We are also evaluating EIK1001 in combination with both pembrolizumab and histology appropriate chemotherapy for the treatment of patients with non-small cell lung cancer, or NSCLC, in a Phase 2 trial, as well as a Phase 2/3 registrational trial for which we recently initiated site selection. We are also conducting Phase 1/2 trials of each of our selective PARP1 inhibitor product candidates, EIK1003 and EIK1004, in ovarian, breast, prostate, and pancreatic cancers and, specifically with the brain-penetrant candidate EIK1004, to address brain metastases and primary brain malignancies. In addition, we have recently initiated a Phase 1/2 trial in patients with advanced solid tumors for EIK1005, our Werner, or WRN, helicase inhibitor that emerged through internal research using our technology platform, which will ultimately be evaluated for the treatment of patients with microsatellite instability-high, or MSI-high, tumors. We were incorporated in Delaware in July 2019. Our principal executive offices are located in Millbrae, California.

Spero Therapeutics stock logo

Spero Therapeutics NASDAQ:SPRO

$2.76 +0.07 (+2.60%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$2.76 0.00 (0.00%)
As of 05/22/2026 04:10 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying, developing, and commercializing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adults; SPR206, an intravenous-administered antibiotic against MDR Gram-negative pathogens comprising carbapenem-resistant enterobacterales (CRE), acinetobacter baumannii, and pseudomonas aeruginosa, as well as negative bacterial infections in the hospital setting; and SPR720, a novel oral antibiotic agent for the treatment of non-tuberculous mycobacterial pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; and Vertex Pharmaceuticals Incorporated for patents relating to SPR720, as well as SPR719, an active metabolite. Spero Therapeutics, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.