Alnylam Pharmaceuticals (ALNY) Stock Forecast & Price Target

$481.67 +0.60 (+0.12%)

Closing price 10/17/2025 04:00 PM Eastern

Extended Trading

$482.39 +0.72 (+0.15%)

As of 10/17/2025 05:48 PM Eastern

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Alnylam Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2025)

Consensus Rating

Moderate Buy

Based on 28 Analyst Ratings

Sell
1

Hold
3

Buy
24

Based on 28 Wall Street analysts who have issued ratings for Alnylam Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 28 analysts, 1 has given a sell rating, 3 have given a hold rating, and 24 have given a buy rating for ALNY.

Consensus Price Target

$463.08
-3.86% Downside

According to the 28 analysts' twelve-month price targets for Alnylam Pharmaceuticals, the average price target is $463.08. The highest price target for ALNY is $583.00, while the lowest price target for ALNY is $310.00. The average price target represents a forecasted downside of -3.86% from the current price of $481.67.

MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.

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ALNY Analyst Ratings Over Time

Type	Current Forecast 10/18/24 to 10/18/25	1 Month Ago 9/18/24 to 9/18/25	3 Months Ago 7/20/24 to 7/20/25	1 Year Ago 10/19/23 to 10/18/24
Strong Buy	0 Strong Buy rating(s)	0 Strong Buy rating(s)	0 Strong Buy rating(s)	0 Strong Buy rating(s)
Buy	24 Buy rating(s)	24 Buy rating(s)	21 Buy rating(s)	18 Buy rating(s)
Hold	3 Hold rating(s)	4 Hold rating(s)	3 Hold rating(s)	6 Hold rating(s)
Sell	1 Sell rating(s)	0 Sell rating(s)	1 Sell rating(s)	0 Sell rating(s)
Consensus Price Target	$463.08	$433.04	$346.13	$286.82
Forecasted Upside	-3.86% Downside	-4.23% Downside	7.99% Upside	-3.08% Downside
Consensus Rating	Moderate Buy	Moderate Buy	Moderate Buy	Moderate Buy

ALNY Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.

ALNY Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.

Alnylam Pharmaceuticals Stock vs. The Competition

Type	Alnylam Pharmaceuticals	Medical Companies	S&P 500
Consensus Rating Score	2.82	2.33	2.52
Consensus Rating	Moderate Buy	Hold	Moderate Buy
Predicted Upside	-3.86% Downside	1,356.33% Upside	13.60% Upside
News Sentiment Rating	Positive News See Recent ALNY News	Positive News	Positive News

Recent Analyst Forecasts and Stock Ratings

Rating

Upside/Downside

Action

Time Frame

Start Date

End Date

Show

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Date	Brokerage	Analyst	Action	Rating	Price Target	Report Date Upside/Downside
10/17/2025	Truist Financial 3 of 5 stars	Danielle Brill Not Rated	Boost Target	Buy	$459.00 ➝ $535.00	+9.80%
10/13/2025	JPMorgan Chase & Co. 2 of 5 stars	Jessica Fye Not Rated	Lower Target	Overweight	$475.00 ➝ $473.00	+3.03%
10/10/2025	HC Wainwright 2 of 5 stars	Patrick R. Trucchio Not Rated	Reiterated Rating	Buy	$570.00	+24.74%
10/8/2025	Weiss Ratings Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating		Reiterated Rating	Sell (D-)
10/6/2025	Morgan Stanley Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Michael Ulz Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Equal Weight	$405.00 ➝ $475.00	+4.55%
10/6/2025	Stifel Nicolaus Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Paul Matteis Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$441.00 ➝ $495.00	+8.47%
9/19/2025	Royal Bank Of Canada Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Luca Issi Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Outperform	$435.00 ➝ $500.00	+10.58%
9/17/2025	Bank of America Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Tazeen Ahmad Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$453.00 ➝ $520.00	+12.46%
9/16/2025	The Goldman Sachs Group Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Salveen Richter Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$504.00 ➝ $566.00	+22.67%
9/11/2025	Evercore ISI Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Liisa Bayko Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Outperform	$280.00 ➝ $515.05	+9.93%
Get the Latest News and Ratings for ALNY and Related Stocks Enter your email address below to receive the latest news and analysts' ratings for Alnylam Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter.
9/5/2025	BMO Capital Markets Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Kostas Biliouris Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Outperform	$450.00 ➝ $470.00	+3.66%
9/2/2025	Citigroup Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	David Lebovitz Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$527.00 ➝ $583.00	+29.48%
8/4/2025	Oppenheimer Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Leland Gershell Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Upgrade	Market Perform ➝ Outperform	$490.00	+21.95%
8/4/2025	Wolfe Research Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Andy Chen Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Upgrade	Underperform ➝ Peer Perform
8/1/2025	Scotiabank Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Greg Harrison Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Sector Outperform	$342.00 ➝ $450.00	+12.00%
8/1/2025	UBS Group Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Eliana Merle Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$403.00 ➝ $550.00	+38.02%
8/1/2025	Canaccord Genuity Group Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Whitney Ijem Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$390.00 ➝ $415.00	+4.88%
8/1/2025	Wells Fargo & Company Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Tiago Fauth Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Equal Weight	$333.00 ➝ $395.00	-0.23%
8/1/2025	Barclays Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Gena Wang Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Overweight	$329.00 ➝ $460.00	+17.28%
8/1/2025	Piper Sandler Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Edward Tenthoff Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Overweight	$304.00 ➝ $449.00	+14.47%
8/1/2025	Chardan Capital Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Keay Nakae Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$325.00 ➝ $400.00	+1.98%
7/31/2025	Needham & Company LLC Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Joseph Stringer Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$377.00 ➝ $478.00	+21.63%
7/30/2025	Raymond James Financial Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Martin Auster Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Initiated Coverage	Outperform	$370.00	+11.93%
7/7/2025	Jefferies Financial Group Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Maury Raycroft Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Boost Target	Buy	$328.00 ➝ $384.00	+18.58%
3/31/2025	Redburn Atlantic Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Joshua Smith Subscribe to MarketBeat All Access for the analyst's recommendation accuracy rating	Initiated Coverage	Buy	$353.00	+31.49%
3/21/2025	William Blair Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating		Reiterated Rating	Outperform
1/7/2025	Sanford C. Bernstein Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating		Lower Target	Outperform	$314.00 ➝ $310.00	+31.53%
10/21/2024	TD Cowen Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating		Boost Target	Buy	$282.00 ➝ $371.00	+25.37%
10/11/2024	Cantor Fitzgerald Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating		Reiterated Rating	Neutral	$220.00 ➝ $220.00	-21.77%
6/25/2024	Leerink Partners Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating		Boost Target	Market Perform	$138.00 ➝ $159.00	-33.15%

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Saturday at 02:48 AM ET.

Should I Buy Alnylam Pharmaceuticals Stock? ALNY Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Friday, October 17, 2025. Please send any questions or comments about these Alnylam Pharmaceuticals pros and cons to contact@marketbeat.com.

Alnylam Pharmaceuticals
Bull Case

Here are some ways that investors could benefit from investing in Alnylam Pharmaceuticals, Inc.:

The stock price has recently been set at approximately $456.35, indicating a strong market position and potential for growth.
Equities research analysts have shown confidence in the company, with a recent price target increase to $495.00, suggesting an expected upside of over 8% from current levels.
Alnylam Pharmaceuticals, Inc. has received multiple "buy" ratings from analysts, reflecting positive sentiment and potential for future performance.
The company has a significant market capitalization of around $59.82 billion, indicating stability and investor confidence in its long-term prospects.
Recent institutional investments, such as KLP Kapitalforvaltning AS increasing its stake by 12.4%, demonstrate growing interest from major investors, which can be a positive signal for retail investors.

Alnylam Pharmaceuticals
Bear Case

Investors should be bearish about investing in Alnylam Pharmaceuticals, Inc. for these reasons:

The company has a high debt-to-equity ratio of 4.10, which may indicate financial risk and reliance on debt financing.
Alnylam Pharmaceuticals, Inc. has a negative PE ratio of -184.76, suggesting that it is not currently profitable, which can be a concern for potential investors.
Despite positive analyst ratings, the stock has experienced volatility, which may deter risk-averse investors.
With a current ratio of 2.80, while it indicates good short-term financial health, it also suggests that the company may be holding excess inventory or cash that could be better utilized for growth.
Market fluctuations and sector-specific challenges in the biopharmaceutical industry could impact the company's performance and stock price in the near term.

ALNY Forecast - Frequently Asked Questions

: According to the research reports of 28 Wall Street equities research analysts, the average twelve-month stock price forecast for Alnylam Pharmaceuticals is $463.08, with a high forecast of $583.00 and a low forecast of $310.00.
: 28 Wall Street equities research analysts have issued "buy," "hold," and "sell" ratings for Alnylam Pharmaceuticals in the last year. There is currently 1 sell rating, 3 hold ratings and 24 buy ratings for the stock. The consensus among Wall Street equities research analysts is that investors should "moderate buy" ALNY shares.
: According to analysts, Alnylam Pharmaceuticals's stock has a predicted downside of -3.86% based on their 12-month stock forecasts.
: Over the previous 90 days, Alnylam Pharmaceuticals's stock had 2 upgrades by analysts.
: Alnylam Pharmaceuticals has been rated by research analysts at Bank of America, Barclays, BMO Capital Markets, Canaccord Genuity Group, Chardan Capital, Citigroup, Evercore ISI, HC Wainwright, JPMorgan Chase & Co., Morgan Stanley, Needham & Company LLC, Oppenheimer, Piper Sandler, Raymond James Financial, Royal Bank Of Canada, Scotiabank, Stifel Nicolaus, The Goldman Sachs Group, Truist Financial, UBS Group, Weiss Ratings, Wells Fargo & Company, and Wolfe Research in the past 90 days.
: Analysts like Alnylam Pharmaceuticals more than other "medical" companies. The consensus rating for Alnylam Pharmaceuticals is Moderate Buy while the average consensus rating for "medical" companies is Hold. Learn more on how ALNY compares to other companies.

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This page (NASDAQ:ALNY) was last updated on 10/18/2025 by MarketBeat.com Staff

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Alnylam Pharmaceuticals (ALNY) Stock Forecast & Price Target