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Alnylam Pharmaceuticals (ALNY) Stock Forecast & Price Target

Alnylam Pharmaceuticals logo
$245.51 +6.15 (+2.57%)
Closing price 04:00 PM Eastern
Extended Trading
$245.40 -0.10 (-0.04%)
As of 06:55 PM Eastern
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Alnylam Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2026)

Consensus Rating

Sell
0
Hold
5
Buy
18

Based on 23 Wall Street analysts who have issued ratings for Alnylam Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 23 analysts, 5 have given a hold rating, 16 have given a buy rating, and 2 have given a strong buy rating for ALNY.

Consensus Price Target

$367.20
49.57% Upside
According to the 23 analysts' twelve-month price targets for Alnylam Pharmaceuticals, the average price target is $367.20. The highest price target for ALNY is $489.00, while the lowest price target for ALNY is $256.00. The average price target represents a forecasted upside of 49.57% from the current price of $245.51.
MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.
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ALNY Analyst Ratings Over Time

TypeCurrent Forecast
9/17/25 to 9/17/26
1 Month Ago
8/18/25 to 8/18/26
3 Months Ago
6/19/25 to 6/19/26
1 Year Ago
9/17/24 to 9/17/25
Strong Buy
2 Strong Buy rating(s)
4 Strong Buy rating(s)
2 Strong Buy rating(s)
0 Strong Buy rating(s)
Buy
16 Buy rating(s)
15 Buy rating(s)
18 Buy rating(s)
24 Buy rating(s)
Hold
5 Hold rating(s)
5 Hold rating(s)
6 Hold rating(s)
4 Hold rating(s)
Sell
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
Consensus Price Target$367.20$393.86$463.13$433.04
Forecasted Upside49.57% Upside72.28% Upside66.54% Upside-4.14% Downside
Consensus RatingModerate BuyModerate BuyModerate BuyModerate Buy

ALNY Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.
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ALNY Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.
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Alnylam Pharmaceuticals Stock vs. The Competition

TypeAlnylam PharmaceuticalsHealthcare CompaniesBroader Market
Consensus Rating Score
2.87
2.30
2.53
Consensus RatingModerate BuyHoldModerate Buy
Predicted Upside52.49% Upside750.80% Upside17.88% Upside
News Sentiment Rating
Positive News

See Recent ALNY News
Positive News
Positive News
DateBrokerageAnalystActionRatingPrice TargetReport Date
Upside/Downside
Details
9/8/2026Boost TargetHold$230.00 ➝ $260.00-0.31%
9/2/2026
HC Wainwright logo
HC Wainwright
4 of 5 stars
Reiterated RatingBuy$455.00+84.88%
8/31/2026
Jeffrey Walch
Jeffrey Walch
Not Rated
Reiterated RatingBuy
8/31/2026 Reiterated RatingBuy
8/31/2026Reiterated RatingOutperform
8/14/2026Lower TargetEqual Weight$316.00 ➝ $256.00+14.69%
8/4/2026Lower TargetBuy$410.00 ➝ $315.00+45.81%
8/3/2026Lower TargetBuy$380.00 ➝ $340.00+57.03%
8/3/2026UpgradeOutperformStrong-Buy$420.00+104.36%
8/3/2026Lower TargetOverweight$527.00 ➝ $450.00+118.96%
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7/31/2026 UpgradeHold (C-)Hold (C)
7/31/2026Lower TargetOutperform$445.00 ➝ $350.00+72.34%
7/31/2026Lower TargetOverweight$400.00 ➝ $375.00+84.65%
7/31/2026Lower TargetEqual Weight$400.00 ➝ $300.00+48.01%
7/31/2026Lower TargetOutperform$500.00 ➝ $350.00+72.59%
7/31/2026Lower TargetBuy$444.00 ➝ $318.00+56.37%
7/31/2026Reiterated RatingBuy$425.00+106.83%
7/30/2026Lower TargetBuy$510.00 ➝ $357.00+76.83%
7/14/2026Lower TargetBuy$460.00 ➝ $410.00+46.17%
2/17/2026 UpgradeHoldStrong-Buy
2/17/2026Boost TargetBuy$415.00 ➝ $429.00+36.62%
12/15/2025Lower TargetMarket Perform$370.00 ➝ $351.00-10.26%
10/31/2025Reiterated RatingOverweight$449.00 ➝ $489.00+8.21%
9/16/2025Boost TargetBuy$504.00 ➝ $566.00+22.67%
9/11/2025Boost TargetOutperform$280.00 ➝ $515.05+9.93%
8/4/2025UpgradeUnderperformPeer Perform
8/1/2025Boost TargetSector Outperform$342.00 ➝ $450.00+12.00%
8/1/2025Boost TargetBuy$403.00 ➝ $550.00+38.02%
3/31/2025Initiated CoverageBuy$353.00+31.49%
3/21/2025 Reiterated RatingOutperform
10/11/2024 Reiterated RatingNeutral$220.00 ➝ $220.00-21.77%

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Thursday at 07:05 PM ET.


Should I Buy Alnylam Pharmaceuticals Stock? ALNY Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Sunday, September 13, 2026. Please send any questions or comments about these Alnylam Pharmaceuticals pros and cons to contact@marketbeat.com.

Alnylam Pharmaceuticals
Bull Case

green Wall Street bull icon

Here are some ways that investors could benefit from investing in Alnylam Pharmaceuticals, Inc.:

  • Alnylam Pharmaceuticals, Inc. recently reported strong financial performance in its most recent quarter, with revenue of $1.29 billion, representing a 66.9% year-over-year increase, and earnings per share of $1.84, which beat analyst consensus estimates of $1.63 by $0.21.
  • The company maintains a "Moderate Buy" consensus rating from research analysts, with a consensus price target of $386.13 as of August 28, 2026, suggesting significant potential upside from the current stock price of $248.68.
  • Alnylam Pharmaceuticals, Inc. has a low beta of 0.31, indicating that the stock is less volatile than the overall market, which may appeal to investors seeking stability in their biotechnology portfolio.
  • The company has a strong balance sheet with a current ratio of 3.05 and a quick ratio of 2.99, demonstrating its ability to cover short-term liabilities with its liquid assets, while maintaining a manageable debt-to-equity ratio of 0.75.
  • Alnylam Pharmaceuticals, Inc. continues to expand its commercial portfolio with products like Amvuttra (vutrisiran) for hATTR amyloidosis and Oxlumo (lumasiran) for primary hyperoxaluria type 1, driving revenue growth and market share in rare disease treatments.

Alnylam Pharmaceuticals
Bear Case

red Wall Street bear icon

Investors should be bearish about investing in Alnylam Pharmaceuticals, Inc. for these reasons:

  • The stock is currently trading at $248.68, which is significantly below its 52-week high of $495.55 and its 200-day moving average of $288.99, indicating a recent downward trend and potential continued pressure on the share price.
  • Several major financial institutions have recently lowered their price targets for Alnylam Pharmaceuticals, Inc., including Wells Fargo, which cut its target from $316.00 to $256.00, and Morgan Stanley, which reduced its target from $400.00 to $300.00, reflecting a more cautious outlook on the company's valuation.
  • Insider selling activity has been notable in recent months, with CEO Yvonne Greenstreet and several other executives selling shares at prices ranging from $310.08 to $453.69, which may signal a lack of confidence in the stock's near-term appreciation.
  • Alnylam Pharmaceuticals, Inc. has a high P/E ratio of 46.22, which is significantly above the market average, suggesting that the stock may be overvalued relative to its current earnings, especially given the recent decline in share price.
  • The company's revenue of $1.29 billion in the most recent quarter fell short of the consensus estimate of $1.32 billion, indicating potential challenges in meeting market expectations for top-line growth despite the strong year-over-year increase.

ALNY Forecast - Frequently Asked Questions

According to the research reports of 23 Wall Street equities research analysts, the average twelve-month stock price forecast for Alnylam Pharmaceuticals is $367.20, with a high forecast of $489.00 and a low forecast of $256.00.

23 Wall Street research analysts have issued "buy," "hold," and "sell" ratings for Alnylam Pharmaceuticals in the last year. There are currently 5 hold ratings, 16 buy ratings and 2 strong buy ratings for the stock. The consensus among Wall Street research analysts is that investors should "moderate buy" ALNY shares.

According to analysts, Alnylam Pharmaceuticals's stock has a predicted upside of 49.57% based on their 12-month stock forecasts.

Over the previous 90 days, Alnylam Pharmaceuticals's stock had 4 upgrades by analysts.

Analysts like Alnylam Pharmaceuticals more than other "healthcare" companies. The consensus rating for Alnylam Pharmaceuticals is Moderate Buy while the average consensus rating for "healthcare" companies is Hold. Learn more on how ALNY compares to other companies.


MarketBeat monitors more than a dozen sources for Alnylam Pharmaceuticals analyst ratings, with the most recent rating issued on 9/8/2026.
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