Amylyx Pharmaceuticals (AMLX) Competitors $8.41 +0.11 (+1.33%) Closing price 04:00 PM EasternExtended Trading$8.36 -0.05 (-0.59%) As of 05:11 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock AMLX vs. RARE, IMVT, ALVO, CRNX, MIRM, CPRX, GMTX, XENE, OGN, and AMRXShould you be buying Amylyx Pharmaceuticals stock or one of its competitors? The main competitors of Amylyx Pharmaceuticals include Ultragenyx Pharmaceutical (RARE), Immunovant (IMVT), Alvotech (ALVO), Crinetics Pharmaceuticals (CRNX), Mirum Pharmaceuticals (MIRM), Catalyst Pharmaceuticals (CPRX), Gemini Therapeutics (GMTX), Xenon Pharmaceuticals (XENE), Organon & Co. (OGN), and AMNEAL PHARMACEUTICALS (AMRX). These companies are all part of the "pharmaceutical products" industry. Amylyx Pharmaceuticals vs. Its Competitors Ultragenyx Pharmaceutical Immunovant Alvotech Crinetics Pharmaceuticals Mirum Pharmaceuticals Catalyst Pharmaceuticals Gemini Therapeutics Xenon Pharmaceuticals Organon & Co. AMNEAL PHARMACEUTICALS Amylyx Pharmaceuticals (NASDAQ:AMLX) and Ultragenyx Pharmaceutical (NASDAQ:RARE) are both medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their earnings, media sentiment, dividends, profitability, institutional ownership, analyst recommendations, risk and valuation. Does the media favor AMLX or RARE? In the previous week, Ultragenyx Pharmaceutical had 39 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 48 mentions for Ultragenyx Pharmaceutical and 9 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 0.27 beat Ultragenyx Pharmaceutical's score of 0.26 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Amylyx Pharmaceuticals 1 Very Positive mention(s) 2 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Ultragenyx Pharmaceutical 12 Very Positive mention(s) 2 Positive mention(s) 7 Neutral mention(s) 2 Negative mention(s) 1 Very Negative mention(s) Neutral Which has more volatility & risk, AMLX or RARE? Amylyx Pharmaceuticals has a beta of -0.46, meaning that its stock price is 146% less volatile than the S&P 500. Comparatively, Ultragenyx Pharmaceutical has a beta of 0.25, meaning that its stock price is 75% less volatile than the S&P 500. Do institutionals and insiders have more ownership in AMLX or RARE? 95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. Comparatively, 97.7% of Ultragenyx Pharmaceutical shares are held by institutional investors. 12.3% of Amylyx Pharmaceuticals shares are held by company insiders. Comparatively, 5.5% of Ultragenyx Pharmaceutical shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term. Do analysts prefer AMLX or RARE? Amylyx Pharmaceuticals currently has a consensus target price of $11.75, suggesting a potential upside of 39.71%. Ultragenyx Pharmaceutical has a consensus target price of $81.50, suggesting a potential upside of 180.94%. Given Ultragenyx Pharmaceutical's higher possible upside, analysts clearly believe Ultragenyx Pharmaceutical is more favorable than Amylyx Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Amylyx Pharmaceuticals 0 Sell rating(s) 2 Hold rating(s) 9 Buy rating(s) 2 Strong Buy rating(s) 3.00Ultragenyx Pharmaceutical 0 Sell rating(s) 1 Hold rating(s) 11 Buy rating(s) 0 Strong Buy rating(s) 2.92 Is AMLX or RARE more profitable? Amylyx Pharmaceuticals has a net margin of 0.00% compared to Ultragenyx Pharmaceutical's net margin of -87.34%. Amylyx Pharmaceuticals' return on equity of -82.48% beat Ultragenyx Pharmaceutical's return on equity.Company Net Margins Return on Equity Return on Assets Amylyx PharmaceuticalsN/A -82.48% -70.15% Ultragenyx Pharmaceutical -87.34%-237.48%-37.66% Which has stronger earnings & valuation, AMLX or RARE? Amylyx Pharmaceuticals has higher earnings, but lower revenue than Ultragenyx Pharmaceutical. Ultragenyx Pharmaceutical is trading at a lower price-to-earnings ratio than Amylyx Pharmaceuticals, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAmylyx Pharmaceuticals-$249K-3,011.62-$301.74M-$2.50-3.36Ultragenyx Pharmaceutical$560.23M4.99-$569.18M-$5.53-5.25 SummaryAmylyx Pharmaceuticals beats Ultragenyx Pharmaceutical on 9 of the 17 factors compared between the two stocks. Get Amylyx Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for AMLX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding AMLX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart AMLX vs. The Competition Export to ExcelMetricAmylyx PharmaceuticalsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$749.89M$2.45B$5.58B$9.81BDividend YieldN/A1.68%4.60%4.11%P/E Ratio-3.3622.0530.2825.72Price / Sales-3,011.62484.52388.3180.18Price / CashN/A183.0237.7558.93Price / Book4.474.718.456.01Net Income-$301.74M$31.61M$3.25B$265.06M7 Day Performance7.27%3.93%4.05%2.80%1 Month PerformanceN/A3.32%4.32%1.68%1 Year Performance294.84%13.53%36.25%29.59% Amylyx Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)AMLXAmylyx Pharmaceuticals3.3343 of 5 stars$8.41+1.3%$11.75+39.7%+317.1%$749.89M-$249K-3.36200News CoverageEarnings ReportRAREUltragenyx Pharmaceutical4.661 of 5 stars$28.46+0.1%$83.08+191.9%-44.1%$2.69B$560.23M-4.841,294Analyst RevisionIMVTImmunovant2.8604 of 5 stars$16.09+2.4%$36.40+126.2%-46.7%$2.69BN/A0.00120News CoverageEarnings ReportAnalyst ForecastAnalyst RevisionALVOAlvotech3.5748 of 5 stars$8.87+0.9%$14.00+57.8%-17.0%$2.65B$491.98M15.151,032News CoverageEarnings ReportShort Interest ↓CRNXCrinetics Pharmaceuticals3.4178 of 5 stars$28.22+1.4%$69.50+146.3%-40.2%$2.61B$1.04M0.00210News CoverageEarnings ReportAnalyst ForecastMIRMMirum Pharmaceuticals3.8909 of 5 stars$52.24+0.4%$65.50+25.4%+58.5%$2.58B$336.89M0.00140Analyst ForecastInsider TradeAnalyst RevisionCPRXCatalyst Pharmaceuticals4.8831 of 5 stars$21.73+2.9%$32.83+51.1%+3.1%$2.58B$491.73M9.0380GMTXGemini TherapeuticsN/A$58.97-1.3%N/A+28.7%$2.56BN/A-58.9730XENEXenon Pharmaceuticals2.0396 of 5 stars$33.16+8.7%$54.82+65.3%-2.9%$2.54B$9.43M-10.27210Trending NewsEarnings ReportAnalyst ForecastAnalyst RevisionHigh Trading VolumeOGNOrganon & Co.4.7977 of 5 stars$9.68-0.7%$18.00+86.0%-54.0%$2.53B$6.40B2.694,000High Trading VolumeAMRXAMNEAL PHARMACEUTICALS3.0503 of 5 stars$7.96+1.7%$11.60+45.7%+19.6%$2.45B$2.79B13.278,100News CoverageInsider Trade Related Companies and Tools Related Companies Ultragenyx Pharmaceutical Competitors Immunovant Competitors Alvotech Competitors Crinetics Pharmaceuticals Competitors Mirum Pharmaceuticals Competitors Catalyst Pharmaceuticals Competitors Gemini Therapeutics Competitors Xenon Pharmaceuticals Competitors Organon & Co. Competitors AMNEAL PHARMACEUTICALS Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:AMLX) was last updated on 8/14/2025 by MarketBeat.com Staff From Our PartnersWhen the levee breaksThe U.S. Treasury just confirmed it plans to borrow $1.01 trillion this quarter—nearly double what was project...Porter & Company | SponsoredIs Elon's empire crumbling?The Tesla Shock Nobody Sees Coming While headlines scream "Tesla is doomed"... 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