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Aprea Therapeutics (APRE) Competitors

Aprea Therapeutics logo
$0.74 0.00 (0.00%)
Closing price 07/2/2026 04:00 PM Eastern
Extended Trading
$0.78 +0.04 (+5.26%)
As of 07/2/2026 07:53 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

APRE vs. MIRA, KALA, GOSS, SCYX, and ACTU

Should you buy Aprea Therapeutics stock or one of its competitors? MarketBeat compares Aprea Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Aprea Therapeutics include MIRA Pharmaceuticals (MIRA), KALA BIO (KALA), Gossamer Bio (GOSS), SCYNEXIS (SCYX), and Actuate Therapeutics (ACTU). These companies are all part of the "pharmaceutical products" industry.

How does Aprea Therapeutics compare to MIRA Pharmaceuticals?

MIRA Pharmaceuticals (NASDAQ:MIRA) and Aprea Therapeutics (NASDAQ:APRE) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their earnings, risk, institutional ownership, dividends, profitability, valuation, media sentiment and analyst recommendations.

MIRA Pharmaceuticals has a beta of 1.48, indicating that its stock price is 48% more volatile than the broader market. Comparatively, Aprea Therapeutics has a beta of 1.5, indicating that its stock price is 50% more volatile than the broader market.

Aprea Therapeutics has a consensus target price of $4.07, suggesting a potential upside of 448.81%. Given Aprea Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Aprea Therapeutics is more favorable than MIRA Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
MIRA Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

35.2% of MIRA Pharmaceuticals shares are owned by institutional investors. Comparatively, 34.2% of Aprea Therapeutics shares are owned by institutional investors. 6.7% of MIRA Pharmaceuticals shares are owned by insiders. Comparatively, 10.5% of Aprea Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

MIRA Pharmaceuticals has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -4,405.59%. Aprea Therapeutics' return on equity of -61.03% beat MIRA Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
MIRA PharmaceuticalsN/A -140.82% -135.01%
Aprea Therapeutics -4,405.59%-61.03%-50.24%

In the previous week, Aprea Therapeutics had 1 more articles in the media than MIRA Pharmaceuticals. MarketBeat recorded 1 mentions for Aprea Therapeutics and 0 mentions for MIRA Pharmaceuticals. Aprea Therapeutics' average media sentiment score of 0.98 beat MIRA Pharmaceuticals' score of 0.00 indicating that Aprea Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
MIRA Pharmaceuticals Neutral
Aprea Therapeutics Positive

MIRA Pharmaceuticals has higher earnings, but lower revenue than Aprea Therapeutics. MIRA Pharmaceuticals is trading at a lower price-to-earnings ratio than Aprea Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
MIRA PharmaceuticalsN/AN/A-$10.44M-$1.30N/A
Aprea Therapeutics$290K31.63-$12.60M-$1.54N/A

Summary

Aprea Therapeutics beats MIRA Pharmaceuticals on 11 of the 15 factors compared between the two stocks.

How does Aprea Therapeutics compare to KALA BIO?

Aprea Therapeutics (NASDAQ:APRE) and KALA BIO (NASDAQ:KALA) are both small-cap medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their institutional ownership, valuation, analyst recommendations, dividends, earnings, media sentiment, risk and profitability.

Aprea Therapeutics has a beta of 1.5, indicating that its share price is 50% more volatile than the broader market. Comparatively, KALA BIO has a beta of -2.35, indicating that its share price is 335% less volatile than the broader market.

Aprea Therapeutics has higher revenue and earnings than KALA BIO. Aprea Therapeutics is trading at a lower price-to-earnings ratio than KALA BIO, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aprea Therapeutics$290K31.63-$12.60M-$1.54N/A
KALA BION/AN/A-$26.98M-$96.14N/A

In the previous week, Aprea Therapeutics had 1 more articles in the media than KALA BIO. MarketBeat recorded 1 mentions for Aprea Therapeutics and 0 mentions for KALA BIO. Aprea Therapeutics' average media sentiment score of 0.98 beat KALA BIO's score of 0.00 indicating that Aprea Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Aprea Therapeutics Positive
KALA BIO Neutral

34.2% of Aprea Therapeutics shares are held by institutional investors. Comparatively, 24.6% of KALA BIO shares are held by institutional investors. 10.5% of Aprea Therapeutics shares are held by company insiders. Comparatively, 2.2% of KALA BIO shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

KALA BIO has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -4,405.59%. Aprea Therapeutics' return on equity of -61.03% beat KALA BIO's return on equity.

Company Net Margins Return on Equity Return on Assets
Aprea Therapeutics-4,405.59% -61.03% -50.24%
KALA BIO N/A -1,336.10%-94.85%

Aprea Therapeutics presently has a consensus target price of $4.07, suggesting a potential upside of 448.81%. KALA BIO has a consensus target price of $1,018.75, suggesting a potential upside of 60,539.88%. Given KALA BIO's higher probable upside, analysts plainly believe KALA BIO is more favorable than Aprea Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
KALA BIO
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

Aprea Therapeutics beats KALA BIO on 12 of the 15 factors compared between the two stocks.

How does Aprea Therapeutics compare to Gossamer Bio?

Gossamer Bio (NASDAQ:GOSS) and Aprea Therapeutics (NASDAQ:APRE) are both small-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their valuation, profitability, institutional ownership, risk, earnings, dividends, media sentiment and analyst recommendations.

Gossamer Bio has a net margin of -324.82% compared to Aprea Therapeutics' net margin of -4,405.59%. Gossamer Bio's return on equity of 0.00% beat Aprea Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Gossamer Bio-324.82% N/A -96.10%
Aprea Therapeutics -4,405.59%-61.03%-50.24%

Gossamer Bio currently has a consensus target price of $4.50, suggesting a potential upside of 2,498.15%. Aprea Therapeutics has a consensus target price of $4.07, suggesting a potential upside of 448.81%. Given Gossamer Bio's higher possible upside, research analysts clearly believe Gossamer Bio is more favorable than Aprea Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Gossamer Bio
2 Sell rating(s)
4 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.20
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

81.2% of Gossamer Bio shares are owned by institutional investors. Comparatively, 34.2% of Aprea Therapeutics shares are owned by institutional investors. 3.7% of Gossamer Bio shares are owned by insiders. Comparatively, 10.5% of Aprea Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Gossamer Bio has a beta of 2.04, meaning that its stock price is 104% more volatile than the broader market. Comparatively, Aprea Therapeutics has a beta of 1.5, meaning that its stock price is 50% more volatile than the broader market.

Aprea Therapeutics has lower revenue, but higher earnings than Gossamer Bio. Aprea Therapeutics is trading at a lower price-to-earnings ratio than Gossamer Bio, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Gossamer Bio$48.47M0.84-$170.37M-$0.79N/A
Aprea Therapeutics$290K31.63-$12.60M-$1.54N/A

In the previous week, Gossamer Bio had 2 more articles in the media than Aprea Therapeutics. MarketBeat recorded 3 mentions for Gossamer Bio and 1 mentions for Aprea Therapeutics. Aprea Therapeutics' average media sentiment score of 0.98 beat Gossamer Bio's score of 0.24 indicating that Aprea Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Gossamer Bio
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Aprea Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Gossamer Bio beats Aprea Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Aprea Therapeutics compare to SCYNEXIS?

SCYNEXIS (NASDAQ:SCYX) and Aprea Therapeutics (NASDAQ:APRE) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, dividends, risk, analyst recommendations, earnings, valuation, profitability and institutional ownership.

SCYNEXIS presently has a consensus target price of $24.00, indicating a potential upside of 441.76%. Aprea Therapeutics has a consensus target price of $4.07, indicating a potential upside of 448.81%. Given Aprea Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Aprea Therapeutics is more favorable than SCYNEXIS.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SCYNEXIS
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

SCYNEXIS has a net margin of -41.79% compared to Aprea Therapeutics' net margin of -4,405.59%. SCYNEXIS's return on equity of -57.16% beat Aprea Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
SCYNEXIS-41.79% -57.16% -39.48%
Aprea Therapeutics -4,405.59%-61.03%-50.24%

54.4% of SCYNEXIS shares are held by institutional investors. Comparatively, 34.2% of Aprea Therapeutics shares are held by institutional investors. 4.1% of SCYNEXIS shares are held by insiders. Comparatively, 10.5% of Aprea Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

SCYNEXIS has higher revenue and earnings than Aprea Therapeutics. SCYNEXIS is trading at a lower price-to-earnings ratio than Aprea Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SCYNEXIS$20.60M2.14-$8.61M-$3.84N/A
Aprea Therapeutics$290K31.63-$12.60M-$1.54N/A

In the previous week, SCYNEXIS and SCYNEXIS both had 1 articles in the media. Aprea Therapeutics' average media sentiment score of 0.98 beat SCYNEXIS's score of 0.00 indicating that Aprea Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SCYNEXIS
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Aprea Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

SCYNEXIS has a beta of 1.11, meaning that its stock price is 11% more volatile than the broader market. Comparatively, Aprea Therapeutics has a beta of 1.5, meaning that its stock price is 50% more volatile than the broader market.

Summary

Aprea Therapeutics beats SCYNEXIS on 9 of the 15 factors compared between the two stocks.

How does Aprea Therapeutics compare to Actuate Therapeutics?

Actuate Therapeutics (NASDAQ:ACTU) and Aprea Therapeutics (NASDAQ:APRE) are both small-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their risk, media sentiment, valuation, dividends, analyst recommendations, earnings, profitability and institutional ownership.

34.2% of Aprea Therapeutics shares are held by institutional investors. 58.0% of Actuate Therapeutics shares are held by insiders. Comparatively, 10.5% of Aprea Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Actuate Therapeutics has a beta of 0.67, indicating that its share price is 33% less volatile than the broader market. Comparatively, Aprea Therapeutics has a beta of 1.5, indicating that its share price is 50% more volatile than the broader market.

Actuate Therapeutics has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -4,405.59%. Aprea Therapeutics' return on equity of -61.03% beat Actuate Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Actuate TherapeuticsN/A -430.93% -180.86%
Aprea Therapeutics -4,405.59%-61.03%-50.24%

Aprea Therapeutics has higher revenue and earnings than Actuate Therapeutics. Actuate Therapeutics is trading at a lower price-to-earnings ratio than Aprea Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Actuate TherapeuticsN/AN/A-$22.23M-$0.97N/A
Aprea Therapeutics$290K31.63-$12.60M-$1.54N/A

Actuate Therapeutics presently has a consensus target price of $17.50, indicating a potential upside of 1,051.32%. Aprea Therapeutics has a consensus target price of $4.07, indicating a potential upside of 448.81%. Given Actuate Therapeutics' higher possible upside, equities research analysts clearly believe Actuate Therapeutics is more favorable than Aprea Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Actuate Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

In the previous week, Aprea Therapeutics had 1 more articles in the media than Actuate Therapeutics. MarketBeat recorded 1 mentions for Aprea Therapeutics and 0 mentions for Actuate Therapeutics. Aprea Therapeutics' average media sentiment score of 0.98 beat Actuate Therapeutics' score of 0.00 indicating that Aprea Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Actuate Therapeutics Neutral
Aprea Therapeutics Positive

Summary

Aprea Therapeutics beats Actuate Therapeutics on 11 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding APRE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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APRE vs. The Competition

MetricAprea TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$9.18M$3.78B$7.16B$12.48B
Dividend YieldN/A2.16%2.66%6.52%
P/E Ratio-0.4821.6128.0224.70
Price / Sales31.63340.22540.5599.42
Price / CashN/A147.1249.2657.09
Price / Book0.498.6610.966.46
Net Income-$12.60M$23.81M$3.57B$337.01M
7 Day Performance-6.20%3.39%2.12%1.69%
1 Month Performance-0.05%10.81%5.25%3.81%
1 Year Performance-57.66%62.61%33.29%23.90%

Aprea Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
APRE
Aprea Therapeutics
4.0286 of 5 stars
$0.74
flat
$4.07
+448.8%
-57.7%$9.18M$290KN/A7
MIRA
MIRA Pharmaceuticals
0.7087 of 5 stars
$0.95
-0.3%
N/A-19.6%$39.90MN/AN/A2
KALA
KALA BIO
2.2254 of 5 stars
$1.73
-17.2%
$1,018.75
+58,787.3%
-99.4%$38.85MN/AN/A30
GOSS
Gossamer Bio
3.0293 of 5 stars
$0.17
+1.8%
$4.50
+2,594.6%
-85.9%$38.49M$48.47MN/A180
SCYX
SCYNEXIS
2.4447 of 5 stars
$4.07
+5.2%
$24.00
+489.7%
-24.2%$38.43M$20.60MN/A60

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This page (NASDAQ:APRE) was last updated on 7/5/2026 by MarketBeat.com Staff.
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