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Aprea Therapeutics (APRE) Competitors

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$0.69 0.00 (0.00%)
Closing price 06/12/2026 04:00 PM Eastern
Extended Trading
$0.70 +0.02 (+2.75%)
As of 06/12/2026 04:14 PM Eastern
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APRE vs. PYRGF, ADXS, GRCE, ABVC, and ATHE

Should you buy Aprea Therapeutics stock or one of its competitors? MarketBeat compares Aprea Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Aprea Therapeutics include PyroGenesis Canada (PYRGF), Ayala Pharmaceuticals (ADXS), Grace Therapeutics (GRCE), ABVC BioPharma (ABVC), and Alterity Therapeutics (ATHE). These companies are all part of the "pharmaceutical products" industry.

How does Aprea Therapeutics compare to PyroGenesis Canada?

Aprea Therapeutics (NASDAQ:APRE) and PyroGenesis Canada (NASDAQ:PYRGF) are both small-cap pharmaceutical products companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, media sentiment, risk, profitability, institutional ownership, analyst recommendations, earnings and valuation.

In the previous week, Aprea Therapeutics and Aprea Therapeutics both had 1 articles in the media. Aprea Therapeutics' average media sentiment score of 1.89 beat PyroGenesis Canada's score of 0.00 indicating that Aprea Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Aprea Therapeutics Very Positive
PyroGenesis Canada Neutral

34.2% of Aprea Therapeutics shares are owned by institutional investors. Comparatively, 0.0% of PyroGenesis Canada shares are owned by institutional investors. 10.5% of Aprea Therapeutics shares are owned by company insiders. Comparatively, 47.7% of PyroGenesis Canada shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Aprea Therapeutics has higher earnings, but lower revenue than PyroGenesis Canada. PyroGenesis Canada is trading at a lower price-to-earnings ratio than Aprea Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aprea Therapeutics$290K29.29-$12.60M-$1.54N/A
PyroGenesis Canada$9.14M4.28-$21.12M-$0.04N/A

Aprea Therapeutics has a beta of 1.51, indicating that its share price is 51% more volatile than the broader market. Comparatively, PyroGenesis Canada has a beta of 0.19, indicating that its share price is 81% less volatile than the broader market.

Aprea Therapeutics currently has a consensus target price of $4.07, suggesting a potential upside of 492.72%. Given Aprea Therapeutics' stronger consensus rating and higher possible upside, equities research analysts clearly believe Aprea Therapeutics is more favorable than PyroGenesis Canada.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
PyroGenesis Canada
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00

PyroGenesis Canada has a net margin of -115.14% compared to Aprea Therapeutics' net margin of -4,405.59%. PyroGenesis Canada's return on equity of 0.00% beat Aprea Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aprea Therapeutics-4,405.59% -61.03% -50.24%
PyroGenesis Canada -115.14%N/A -60.81%

Summary

Aprea Therapeutics beats PyroGenesis Canada on 10 of the 15 factors compared between the two stocks.

How does Aprea Therapeutics compare to Ayala Pharmaceuticals?

Aprea Therapeutics (NASDAQ:APRE) and Ayala Pharmaceuticals (NASDAQ:ADXS) are both small-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their dividends, analyst recommendations, risk, media sentiment, institutional ownership, earnings, valuation and profitability.

Aprea Therapeutics has higher earnings, but lower revenue than Ayala Pharmaceuticals. Aprea Therapeutics is trading at a lower price-to-earnings ratio than Ayala Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aprea Therapeutics$290K29.29-$12.60M-$1.54N/A
Ayala Pharmaceuticals$3.24M11.05-$48.07M-$5.02N/A

In the previous week, Aprea Therapeutics had 1 more articles in the media than Ayala Pharmaceuticals. MarketBeat recorded 1 mentions for Aprea Therapeutics and 0 mentions for Ayala Pharmaceuticals. Aprea Therapeutics' average media sentiment score of 1.89 beat Ayala Pharmaceuticals' score of 0.00 indicating that Aprea Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Aprea Therapeutics Very Positive
Ayala Pharmaceuticals Neutral

Ayala Pharmaceuticals has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -4,405.59%. Ayala Pharmaceuticals' return on equity of 0.00% beat Aprea Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aprea Therapeutics-4,405.59% -61.03% -50.24%
Ayala Pharmaceuticals N/A N/A N/A

34.2% of Aprea Therapeutics shares are held by institutional investors. Comparatively, 7.2% of Ayala Pharmaceuticals shares are held by institutional investors. 10.5% of Aprea Therapeutics shares are held by insiders. Comparatively, 0.6% of Ayala Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Aprea Therapeutics has a beta of 1.51, meaning that its stock price is 51% more volatile than the broader market. Comparatively, Ayala Pharmaceuticals has a beta of 1.75, meaning that its stock price is 75% more volatile than the broader market.

Aprea Therapeutics presently has a consensus target price of $4.07, suggesting a potential upside of 492.72%. Given Aprea Therapeutics' stronger consensus rating and higher probable upside, equities research analysts clearly believe Aprea Therapeutics is more favorable than Ayala Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Ayala Pharmaceuticals
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00

Summary

Aprea Therapeutics beats Ayala Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

How does Aprea Therapeutics compare to Grace Therapeutics?

Aprea Therapeutics (NASDAQ:APRE) and Grace Therapeutics (NASDAQ:GRCE) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their profitability, institutional ownership, valuation, earnings, dividends, media sentiment, risk and analyst recommendations.

Aprea Therapeutics has a beta of 1.51, suggesting that its share price is 51% more volatile than the broader market. Comparatively, Grace Therapeutics has a beta of 0.37, suggesting that its share price is 63% less volatile than the broader market.

34.2% of Aprea Therapeutics shares are held by institutional investors. Comparatively, 6.1% of Grace Therapeutics shares are held by institutional investors. 10.5% of Aprea Therapeutics shares are held by company insiders. Comparatively, 11.1% of Grace Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Grace Therapeutics has lower revenue, but higher earnings than Aprea Therapeutics. Grace Therapeutics is trading at a lower price-to-earnings ratio than Aprea Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aprea Therapeutics$290K29.29-$12.60M-$1.54N/A
Grace TherapeuticsN/AN/A-$9.57M-$0.40N/A

In the previous week, Grace Therapeutics had 4 more articles in the media than Aprea Therapeutics. MarketBeat recorded 5 mentions for Grace Therapeutics and 1 mentions for Aprea Therapeutics. Aprea Therapeutics' average media sentiment score of 1.89 beat Grace Therapeutics' score of 0.71 indicating that Aprea Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Aprea Therapeutics Very Positive
Grace Therapeutics Positive

Aprea Therapeutics currently has a consensus target price of $4.07, indicating a potential upside of 492.72%. Grace Therapeutics has a consensus target price of $6.00, indicating a potential upside of 172.73%. Given Aprea Therapeutics' stronger consensus rating and higher probable upside, research analysts clearly believe Aprea Therapeutics is more favorable than Grace Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Grace Therapeutics
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Grace Therapeutics has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -4,405.59%. Grace Therapeutics' return on equity of -15.58% beat Aprea Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aprea Therapeutics-4,405.59% -61.03% -50.24%
Grace Therapeutics N/A -15.58%-14.51%

Summary

Aprea Therapeutics beats Grace Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Aprea Therapeutics compare to ABVC BioPharma?

ABVC BioPharma (NASDAQ:ABVC) and Aprea Therapeutics (NASDAQ:APRE) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their profitability, media sentiment, dividends, institutional ownership, analyst recommendations, valuation, earnings and risk.

ABVC BioPharma has higher revenue and earnings than Aprea Therapeutics. ABVC BioPharma is trading at a lower price-to-earnings ratio than Aprea Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ABVC BioPharma$510K60.67-$7.91M-$0.40N/A
Aprea Therapeutics$290K29.29-$12.60M-$1.54N/A

ABVC BioPharma has a beta of 0.56, indicating that its stock price is 44% less volatile than the broader market. Comparatively, Aprea Therapeutics has a beta of 1.51, indicating that its stock price is 51% more volatile than the broader market.

Aprea Therapeutics has a consensus target price of $4.07, suggesting a potential upside of 492.72%. Given Aprea Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Aprea Therapeutics is more favorable than ABVC BioPharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
ABVC BioPharma
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

11.4% of ABVC BioPharma shares are owned by institutional investors. Comparatively, 34.2% of Aprea Therapeutics shares are owned by institutional investors. 19.0% of ABVC BioPharma shares are owned by company insiders. Comparatively, 10.5% of Aprea Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

In the previous week, ABVC BioPharma and ABVC BioPharma both had 1 articles in the media. Aprea Therapeutics' average media sentiment score of 1.89 beat ABVC BioPharma's score of 1.87 indicating that Aprea Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
ABVC BioPharma Very Positive
Aprea Therapeutics Very Positive

ABVC BioPharma has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -4,405.59%. Aprea Therapeutics' return on equity of -61.03% beat ABVC BioPharma's return on equity.

Company Net Margins Return on Equity Return on Assets
ABVC BioPharmaN/A -62.46% -39.99%
Aprea Therapeutics -4,405.59%-61.03%-50.24%

Summary

Aprea Therapeutics beats ABVC BioPharma on 8 of the 15 factors compared between the two stocks.

How does Aprea Therapeutics compare to Alterity Therapeutics?

Aprea Therapeutics (NASDAQ:APRE) and Alterity Therapeutics (NASDAQ:ATHE) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their dividends, institutional ownership, risk, profitability, media sentiment, valuation, analyst recommendations and earnings.

Aprea Therapeutics has a beta of 1.51, meaning that its share price is 51% more volatile than the broader market. Comparatively, Alterity Therapeutics has a beta of 0.31, meaning that its share price is 69% less volatile than the broader market.

Alterity Therapeutics has lower revenue, but higher earnings than Aprea Therapeutics.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aprea Therapeutics$290K29.29-$12.60M-$1.54N/A
Alterity TherapeuticsN/AN/A-$7.87MN/AN/A

34.2% of Aprea Therapeutics shares are owned by institutional investors. Comparatively, 2.1% of Alterity Therapeutics shares are owned by institutional investors. 10.5% of Aprea Therapeutics shares are owned by company insiders. Comparatively, 38.8% of Alterity Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

In the previous week, Alterity Therapeutics had 2 more articles in the media than Aprea Therapeutics. MarketBeat recorded 3 mentions for Alterity Therapeutics and 1 mentions for Aprea Therapeutics. Aprea Therapeutics' average media sentiment score of 1.89 beat Alterity Therapeutics' score of 0.36 indicating that Aprea Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Aprea Therapeutics Very Positive
Alterity Therapeutics Neutral

Alterity Therapeutics has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -4,405.59%. Alterity Therapeutics' return on equity of 0.00% beat Aprea Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aprea Therapeutics-4,405.59% -61.03% -50.24%
Alterity Therapeutics N/A N/A N/A

Aprea Therapeutics presently has a consensus price target of $4.07, indicating a potential upside of 492.72%. Given Aprea Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Aprea Therapeutics is more favorable than Alterity Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aprea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Alterity Therapeutics
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

Aprea Therapeutics beats Alterity Therapeutics on 7 of the 13 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding APRE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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APRE vs. The Competition

MetricAprea TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$8.49M$3.39B$6.52B$12.05B
Dividend YieldN/A2.25%2.67%5.66%
P/E Ratio-0.4520.0024.0024.42
Price / Sales29.29306.76515.84118.72
Price / CashN/A53.6127.4837.92
Price / Book0.458.3210.606.82
Net Income-$12.60M$23.94M$3.57B$337.56M
7 Day Performance-6.56%1.84%0.59%1.16%
1 Month Performance-26.23%-0.04%1.54%3.16%
1 Year Performance-63.70%44.82%25.41%30.60%

Aprea Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
APRE
Aprea Therapeutics
4.3246 of 5 stars
$0.69
flat
$4.07
+492.7%
-63.7%$8.49M$290KN/A7
PYRGF
PyroGenesis Canada
N/A$0.18
-0.1%
N/A-45.1%$36.32M$9.14MN/A90
ADXS
Ayala Pharmaceuticals
N/A$0.60
flat
N/AN/A$35.79M$3.24MN/A20
GRCE
Grace Therapeutics
2.6909 of 5 stars
$2.33
+1.3%
$6.00
+157.5%
-22.5%$35.59MN/AN/AN/A
ABVC
ABVC BioPharma
1.069 of 5 stars
$1.32
-1.5%
N/A-32.8%$34.84M$510KN/A30

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This page (NASDAQ:APRE) was last updated on 6/15/2026 by MarketBeat.com Staff.
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