Dyadic International (DYAI) Competitors

Dyadic International logo
$0.80 +0.06 (+8.10%)
Closing price 06/26/2026 04:00 PM Eastern
Extended Trading
$0.82 +0.02 (+2.37%)
As of 06/26/2026 07:59 PM Eastern
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DYAI vs. COYA, PYXS, CUE, CGTX, and PLYX

Should you buy Dyadic International stock or one of its competitors? MarketBeat compares Dyadic International with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Dyadic International include Coya Therapeutics (COYA), Pyxis Oncology (PYXS), Cue Biopharma (CUE), Cognition Therapeutics (CGTX), and Polaryx Therapeutics (PLYX). These companies are all part of the "pharmaceutical products" industry.

How does Dyadic International compare to Coya Therapeutics?

Dyadic International (NASDAQ:DYAI) and Coya Therapeutics (NASDAQ:COYA) are both small-cap medical companies, but which is the superior investment? We will compare the two companies based on the strength of their valuation, profitability, dividends, analyst recommendations, earnings, institutional ownership, media sentiment and risk.

In the previous week, Dyadic International had 2 more articles in the media than Coya Therapeutics. MarketBeat recorded 4 mentions for Dyadic International and 2 mentions for Coya Therapeutics. Coya Therapeutics' average media sentiment score of 0.94 beat Dyadic International's score of 0.57 indicating that Coya Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Dyadic International
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Coya Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

28.0% of Dyadic International shares are owned by institutional investors. Comparatively, 39.8% of Coya Therapeutics shares are owned by institutional investors. 20.9% of Dyadic International shares are owned by insiders. Comparatively, 6.1% of Coya Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Dyadic International has a net margin of -192.40% compared to Coya Therapeutics' net margin of -266.10%. Coya Therapeutics' return on equity of -55.86% beat Dyadic International's return on equity.

Company Net Margins Return on Equity Return on Assets
Dyadic International-192.40% -1,005.45% -77.64%
Coya Therapeutics -266.10%-55.86%-48.86%

Dyadic International presently has a consensus target price of $3.00, suggesting a potential upside of 274.53%. Coya Therapeutics has a consensus target price of $15.33, suggesting a potential upside of 178.79%. Given Dyadic International's higher probable upside, equities analysts plainly believe Dyadic International is more favorable than Coya Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Dyadic International
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Coya Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

Dyadic International has a beta of 1.17, meaning that its share price is 17% more volatile than the broader market. Comparatively, Coya Therapeutics has a beta of 0.62, meaning that its share price is 38% less volatile than the broader market.

Dyadic International has higher earnings, but lower revenue than Coya Therapeutics. Coya Therapeutics is trading at a lower price-to-earnings ratio than Dyadic International, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Dyadic International$3.09M9.45-$7.36M-$0.23N/A
Coya Therapeutics$7.95M16.23-$21.23M-$1.15N/A

Summary

Dyadic International and Coya Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Dyadic International compare to Pyxis Oncology?

Pyxis Oncology (NASDAQ:PYXS) and Dyadic International (NASDAQ:DYAI) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their risk, dividends, profitability, media sentiment, valuation, institutional ownership, earnings and analyst recommendations.

In the previous week, Dyadic International had 1 more articles in the media than Pyxis Oncology. MarketBeat recorded 4 mentions for Dyadic International and 3 mentions for Pyxis Oncology. Pyxis Oncology's average media sentiment score of 0.62 beat Dyadic International's score of 0.57 indicating that Pyxis Oncology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pyxis Oncology
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Dyadic International
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Pyxis Oncology currently has a consensus target price of $6.83, indicating a potential upside of 146.69%. Dyadic International has a consensus target price of $3.00, indicating a potential upside of 274.53%. Given Dyadic International's higher probable upside, analysts clearly believe Dyadic International is more favorable than Pyxis Oncology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.63
Dyadic International
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

Pyxis Oncology has a net margin of 0.00% compared to Dyadic International's net margin of -192.40%. Pyxis Oncology's return on equity of -135.60% beat Dyadic International's return on equity.

Company Net Margins Return on Equity Return on Assets
Pyxis OncologyN/A -135.60% -85.00%
Dyadic International -192.40%-1,005.45%-77.64%

Pyxis Oncology has a beta of 1.42, suggesting that its stock price is 42% more volatile than the broader market. Comparatively, Dyadic International has a beta of 1.17, suggesting that its stock price is 17% more volatile than the broader market.

39.1% of Pyxis Oncology shares are owned by institutional investors. Comparatively, 28.0% of Dyadic International shares are owned by institutional investors. 5.7% of Pyxis Oncology shares are owned by insiders. Comparatively, 20.9% of Dyadic International shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Dyadic International has lower revenue, but higher earnings than Pyxis Oncology. Dyadic International is trading at a lower price-to-earnings ratio than Pyxis Oncology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pyxis Oncology$13.86M12.66-$79.62M-$1.31N/A
Dyadic International$3.09M9.45-$7.36M-$0.23N/A

Summary

Pyxis Oncology beats Dyadic International on 10 of the 16 factors compared between the two stocks.

How does Dyadic International compare to Cue Biopharma?

Cue Biopharma (NASDAQ:CUE) and Dyadic International (NASDAQ:DYAI) are both small-cap medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their risk, analyst recommendations, valuation, earnings, institutional ownership, profitability, media sentiment and dividends.

35.0% of Cue Biopharma shares are held by institutional investors. Comparatively, 28.0% of Dyadic International shares are held by institutional investors. 14.6% of Cue Biopharma shares are held by company insiders. Comparatively, 20.9% of Dyadic International shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Dyadic International has a consensus target price of $3.00, suggesting a potential upside of 274.53%. Given Dyadic International's stronger consensus rating and higher possible upside, analysts clearly believe Dyadic International is more favorable than Cue Biopharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cue Biopharma
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Dyadic International
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

Dyadic International has lower revenue, but higher earnings than Cue Biopharma. Cue Biopharma is trading at a lower price-to-earnings ratio than Dyadic International, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cue Biopharma$27.47M3.88-$26.60M-$5.58N/A
Dyadic International$3.09M9.45-$7.36M-$0.23N/A

In the previous week, Dyadic International had 3 more articles in the media than Cue Biopharma. MarketBeat recorded 4 mentions for Dyadic International and 1 mentions for Cue Biopharma. Cue Biopharma's average media sentiment score of 1.89 beat Dyadic International's score of 0.57 indicating that Cue Biopharma is being referred to more favorably in the media.

Company Overall Sentiment
Cue Biopharma Very Positive
Dyadic International Positive

Cue Biopharma has a net margin of -59.65% compared to Dyadic International's net margin of -192.40%. Cue Biopharma's return on equity of -98.30% beat Dyadic International's return on equity.

Company Net Margins Return on Equity Return on Assets
Cue Biopharma-59.65% -98.30% -53.69%
Dyadic International -192.40%-1,005.45%-77.64%

Cue Biopharma has a beta of 2.52, suggesting that its stock price is 152% more volatile than the broader market. Comparatively, Dyadic International has a beta of 1.17, suggesting that its stock price is 17% more volatile than the broader market.

Summary

Dyadic International beats Cue Biopharma on 9 of the 16 factors compared between the two stocks.

How does Dyadic International compare to Cognition Therapeutics?

Cognition Therapeutics (NASDAQ:CGTX) and Dyadic International (NASDAQ:DYAI) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their profitability, media sentiment, dividends, valuation, risk, institutional ownership, analyst recommendations and earnings.

43.4% of Cognition Therapeutics shares are held by institutional investors. Comparatively, 28.0% of Dyadic International shares are held by institutional investors. 11.1% of Cognition Therapeutics shares are held by company insiders. Comparatively, 20.9% of Dyadic International shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

In the previous week, Cognition Therapeutics had 2 more articles in the media than Dyadic International. MarketBeat recorded 6 mentions for Cognition Therapeutics and 4 mentions for Dyadic International. Cognition Therapeutics' average media sentiment score of 1.04 beat Dyadic International's score of 0.57 indicating that Cognition Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Cognition Therapeutics
1 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Dyadic International
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Dyadic International has higher revenue and earnings than Cognition Therapeutics. Cognition Therapeutics is trading at a lower price-to-earnings ratio than Dyadic International, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cognition TherapeuticsN/AN/A-$23.49M-$0.24N/A
Dyadic International$3.09M9.45-$7.36M-$0.23N/A

Cognition Therapeutics has a beta of 1.75, meaning that its stock price is 75% more volatile than the broader market. Comparatively, Dyadic International has a beta of 1.17, meaning that its stock price is 17% more volatile than the broader market.

Cognition Therapeutics currently has a consensus target price of $3.33, suggesting a potential upside of 197.62%. Dyadic International has a consensus target price of $3.00, suggesting a potential upside of 274.53%. Given Dyadic International's higher probable upside, analysts plainly believe Dyadic International is more favorable than Cognition Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cognition Therapeutics
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Dyadic International
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

Cognition Therapeutics has a net margin of 0.00% compared to Dyadic International's net margin of -192.40%. Cognition Therapeutics' return on equity of -72.68% beat Dyadic International's return on equity.

Company Net Margins Return on Equity Return on Assets
Cognition TherapeuticsN/A -72.68% -53.07%
Dyadic International -192.40%-1,005.45%-77.64%

Summary

Cognition Therapeutics beats Dyadic International on 9 of the 15 factors compared between the two stocks.

How does Dyadic International compare to Polaryx Therapeutics?

Dyadic International (NASDAQ:DYAI) and Polaryx Therapeutics (NASDAQ:PLYX) are both small-cap pharmaceutical products companies, but which is the better stock? We will contrast the two companies based on the strength of their media sentiment, profitability, institutional ownership, valuation, earnings, dividends, analyst recommendations and risk.

In the previous week, Dyadic International had 3 more articles in the media than Polaryx Therapeutics. MarketBeat recorded 4 mentions for Dyadic International and 1 mentions for Polaryx Therapeutics. Polaryx Therapeutics' average media sentiment score of 1.89 beat Dyadic International's score of 0.57 indicating that Polaryx Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Dyadic International Positive
Polaryx Therapeutics Very Positive

Dyadic International currently has a consensus price target of $3.00, indicating a potential upside of 274.53%. Polaryx Therapeutics has a consensus price target of $10.00, indicating a potential upside of 316.67%. Given Polaryx Therapeutics' higher possible upside, analysts clearly believe Polaryx Therapeutics is more favorable than Dyadic International.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Dyadic International
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Polaryx Therapeutics
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Polaryx Therapeutics has lower revenue, but higher earnings than Dyadic International.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Dyadic International$3.09M9.45-$7.36M-$0.23N/A
Polaryx TherapeuticsN/AN/AN/AN/AN/A

Polaryx Therapeutics has a net margin of 0.00% compared to Dyadic International's net margin of -192.40%. Polaryx Therapeutics' return on equity of 0.00% beat Dyadic International's return on equity.

Company Net Margins Return on Equity Return on Assets
Dyadic International-192.40% -1,005.45% -77.64%
Polaryx Therapeutics N/A N/A N/A

28.0% of Dyadic International shares are held by institutional investors. 20.9% of Dyadic International shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Summary

Dyadic International beats Polaryx Therapeutics on 6 of the 11 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding DYAI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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DYAI vs. The Competition

MetricDyadic InternationalMED IndustryMedical SectorNASDAQ Exchange
Market Cap$27M$3.55B$6.70B$12.22B
Dividend YieldN/A2.25%2.67%6.13%
P/E Ratio-3.4821.5625.7624.17
Price / Sales9.45334.67559.68101.60
Price / CashN/A137.3846.9954.37
Price / Book26.708.3410.776.35
Net Income-$7.36M$23.91M$3.57B$337.63M
7 Day Performance2.43%3.38%2.15%0.06%
1 Month Performance5.41%1.51%1.06%-0.15%
1 Year Performance-19.81%65.14%34.16%27.55%

Dyadic International Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
DYAI
Dyadic International
3.0487 of 5 stars
$0.80
+8.1%
$3.00
+274.5%
-19.5%$27M$3.09MN/A7
COYA
Coya Therapeutics
2.3801 of 5 stars
$4.82
-1.4%
$15.33
+218.1%
-6.8%$114.71M$7.95MN/A6
PYXS
Pyxis Oncology
2.47 of 5 stars
$1.75
+0.6%
$6.83
+290.5%
+134.7%$110.24M$13.86MN/A60
CUE
Cue Biopharma
0.5496 of 5 stars
$23.89
-7.4%
N/A-96.4%$108.37M$27.47MN/A60
CGTX
Cognition Therapeutics
3.9726 of 5 stars
$1.26
+4.1%
$3.33
+164.6%
+245.1%$108.29MN/AN/A20

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This page (NASDAQ:DYAI) was last updated on 6/27/2026 by MarketBeat.com Staff.
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