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Equillium (EQ) Competitors

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$1.75 -0.18 (-9.33%)
Closing price 09/23/2026 04:00 PM Eastern
Extended Trading
$1.80 +0.05 (+2.86%)
As of 09/23/2026 07:55 PM Eastern
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EQ vs. EIKN, PRTA, KYTX, EDIT, and IRD

Should you buy Equillium stock or one of its competitors? Equillium's main competitors and comparable companies include Eikon Therapeutics (EIKN), Prothena (PRTA), Kyverna Therapeutics (KYTX), Editas Medicine (EDIT), and Opus Genetics (IRD). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Equillium compare to Eikon Therapeutics?

Equillium (NASDAQ:EQ) and Eikon Therapeutics (NASDAQ:EIKN) are both small-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their profitability, risk, institutional ownership, valuation, media sentiment, dividends, analyst recommendations and earnings.

Equillium currently has a consensus target price of $7.57, indicating a potential upside of 332.65%. Eikon Therapeutics has a consensus target price of $25.00, indicating a potential upside of 207.50%. Given Equillium's stronger consensus rating and higher probable upside, analysts plainly believe Equillium is more favorable than Eikon Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Equillium
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Eikon Therapeutics
2 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.50

Equillium is trading at a lower price-to-earnings ratio than Eikon Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
EquilliumN/AN/A-$22.40M-$0.20N/A
Eikon TherapeuticsN/AN/A-$324.25M-$4.09N/A

In the previous week, Eikon Therapeutics had 2 more articles in the media than Equillium. MarketBeat recorded 5 mentions for Eikon Therapeutics and 3 mentions for Equillium. Eikon Therapeutics' average media sentiment score of 0.67 beat Equillium's score of -0.28 indicating that Eikon Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Equillium
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Eikon Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

27.0% of Equillium shares are held by institutional investors. 17.8% of Equillium shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Eikon Therapeutics' return on equity of 0.00% beat Equillium's return on equity.

Company Net Margins Return on Equity Return on Assets
EquilliumN/A -41.15% -38.29%
Eikon Therapeutics N/A N/A N/A

Summary

Equillium beats Eikon Therapeutics on 8 of the 13 factors compared between the two stocks.

How does Equillium compare to Prothena?

Equillium (NASDAQ:EQ) and Prothena (NASDAQ:PRTA) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, valuation, institutional ownership, media sentiment, analyst recommendations, dividends, earnings and profitability.

Equillium has a beta of 1.81, indicating that its share price is 81% more volatile than the broader market. Comparatively, Prothena has a beta of -0.33, indicating that its share price is 133% less volatile than the broader market.

Equillium has higher earnings, but lower revenue than Prothena. Prothena is trading at a lower price-to-earnings ratio than Equillium, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
EquilliumN/AN/A-$22.40M-$0.20N/A
Prothena$9.68M46.94-$244.09M-$0.84N/A

In the previous week, Prothena had 3 more articles in the media than Equillium. MarketBeat recorded 6 mentions for Prothena and 3 mentions for Equillium. Prothena's average media sentiment score of 1.18 beat Equillium's score of -0.28 indicating that Prothena is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Equillium
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Prothena
3 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Equillium currently has a consensus target price of $7.57, indicating a potential upside of 332.65%. Prothena has a consensus target price of $24.57, indicating a potential upside of 183.08%. Given Equillium's stronger consensus rating and higher probable upside, equities research analysts plainly believe Equillium is more favorable than Prothena.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Equillium
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Prothena
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75

Equillium has a net margin of 0.00% compared to Prothena's net margin of -80.68%. Prothena's return on equity of -16.45% beat Equillium's return on equity.

Company Net Margins Return on Equity Return on Assets
EquilliumN/A -41.15% -38.29%
Prothena -80.68%-16.45%-14.51%

27.0% of Equillium shares are held by institutional investors. Comparatively, 97.1% of Prothena shares are held by institutional investors. 17.8% of Equillium shares are held by company insiders. Comparatively, 10.4% of Prothena shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Summary

Equillium beats Prothena on 10 of the 16 factors compared between the two stocks.

How does Equillium compare to Kyverna Therapeutics?

Equillium (NASDAQ:EQ) and Kyverna Therapeutics (NASDAQ:KYTX) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, profitability, risk, institutional ownership, valuation, dividends, media sentiment and earnings.

Equillium currently has a consensus price target of $7.57, suggesting a potential upside of 332.65%. Kyverna Therapeutics has a consensus price target of $30.00, suggesting a potential upside of 324.33%. Given Equillium's stronger consensus rating and higher probable upside, equities research analysts plainly believe Equillium is more favorable than Kyverna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Equillium
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Kyverna Therapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.60

27.0% of Equillium shares are held by institutional investors. Comparatively, 18.1% of Kyverna Therapeutics shares are held by institutional investors. 17.8% of Equillium shares are held by insiders. Comparatively, 17.6% of Kyverna Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Equillium is trading at a lower price-to-earnings ratio than Kyverna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
EquilliumN/AN/A-$22.40M-$0.20N/A
Kyverna TherapeuticsN/AN/A-$161.31M-$2.94N/A

In the previous week, Equillium had 2 more articles in the media than Kyverna Therapeutics. MarketBeat recorded 3 mentions for Equillium and 1 mentions for Kyverna Therapeutics. Kyverna Therapeutics' average media sentiment score of 0.00 beat Equillium's score of -0.28 indicating that Kyverna Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Equillium
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Kyverna Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Equillium has a beta of 1.81, meaning that its share price is 81% more volatile than the broader market. Comparatively, Kyverna Therapeutics has a beta of 1.98, meaning that its share price is 98% more volatile than the broader market.

Equillium's return on equity of -41.15% beat Kyverna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
EquilliumN/A -41.15% -38.29%
Kyverna Therapeutics N/A -81.92%-63.74%

Summary

Equillium beats Kyverna Therapeutics on 11 of the 14 factors compared between the two stocks.

How does Equillium compare to Editas Medicine?

Equillium (NASDAQ:EQ) and Editas Medicine (NASDAQ:EDIT) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their earnings, profitability, analyst recommendations, media sentiment, dividends, institutional ownership, valuation and risk.

Equillium currently has a consensus target price of $7.57, indicating a potential upside of 332.65%. Editas Medicine has a consensus target price of $5.80, indicating a potential upside of 115.61%. Given Equillium's stronger consensus rating and higher possible upside, analysts clearly believe Equillium is more favorable than Editas Medicine.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Equillium
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Editas Medicine
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.67

Equillium has a net margin of 0.00% compared to Editas Medicine's net margin of -157.32%. Equillium's return on equity of -41.15% beat Editas Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
EquilliumN/A -41.15% -38.29%
Editas Medicine -157.32%-196.63%-38.17%

Equillium has a beta of 1.81, meaning that its stock price is 81% more volatile than the broader market. Comparatively, Editas Medicine has a beta of 2.09, meaning that its stock price is 109% more volatile than the broader market.

27.0% of Equillium shares are owned by institutional investors. Comparatively, 71.9% of Editas Medicine shares are owned by institutional investors. 17.8% of Equillium shares are owned by company insiders. Comparatively, 3.1% of Editas Medicine shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Equillium has higher earnings, but lower revenue than Editas Medicine. Equillium is trading at a lower price-to-earnings ratio than Editas Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
EquilliumN/AN/A-$22.40M-$0.20N/A
Editas Medicine$40.52M10.20-$160.06M-$0.75N/A

In the previous week, Editas Medicine had 3 more articles in the media than Equillium. MarketBeat recorded 6 mentions for Editas Medicine and 3 mentions for Equillium. Editas Medicine's average media sentiment score of 0.37 beat Equillium's score of -0.28 indicating that Editas Medicine is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Equillium
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Editas Medicine
0 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Equillium beats Editas Medicine on 9 of the 16 factors compared between the two stocks.

How does Equillium compare to Opus Genetics?

Equillium (NASDAQ:EQ) and Opus Genetics (NASDAQ:IRD) are both small-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their earnings, profitability, valuation, analyst recommendations, media sentiment, risk, institutional ownership and dividends.

Equillium has a net margin of 0.00% compared to Opus Genetics' net margin of -1,091.82%. Equillium's return on equity of -41.15% beat Opus Genetics' return on equity.

Company Net Margins Return on Equity Return on Assets
EquilliumN/A -41.15% -38.29%
Opus Genetics -1,091.82%-338.88%-150.13%

Equillium currently has a consensus target price of $7.57, indicating a potential upside of 332.65%. Opus Genetics has a consensus target price of $11.92, indicating a potential upside of 146.85%. Given Equillium's stronger consensus rating and higher probable upside, equities research analysts plainly believe Equillium is more favorable than Opus Genetics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Equillium
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Opus Genetics
1 Sell rating(s)
1 Hold rating(s)
15 Buy rating(s)
1 Strong Buy rating(s)
2.89

In the previous week, Equillium had 3 more articles in the media than Opus Genetics. MarketBeat recorded 3 mentions for Equillium and 0 mentions for Opus Genetics. Opus Genetics' average media sentiment score of 1.73 beat Equillium's score of -0.28 indicating that Opus Genetics is being referred to more favorably in the news media.

Company Overall Sentiment
Equillium Neutral
Opus Genetics Very Positive

Equillium has higher earnings, but lower revenue than Opus Genetics. Equillium is trading at a lower price-to-earnings ratio than Opus Genetics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
EquilliumN/AN/A-$22.40M-$0.20N/A
Opus Genetics$14.20M28.11-$49.59M-$1.35N/A

27.0% of Equillium shares are held by institutional investors. Comparatively, 15.0% of Opus Genetics shares are held by institutional investors. 17.8% of Equillium shares are held by company insiders. Comparatively, 11.7% of Opus Genetics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Equillium has a beta of 1.81, indicating that its share price is 81% more volatile than the broader market. Comparatively, Opus Genetics has a beta of 0.58, indicating that its share price is 42% less volatile than the broader market.

Summary

Equillium beats Opus Genetics on 12 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding EQ and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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EQ vs. The Competition

MetricEquilliumBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$122.38M$3.98B$7.31B$13.29B
Dividend YieldN/A3.63%2.52%12.57%
P/E Ratio-8.7513.88274.0825.69
Price / SalesN/A1,343.77638.2178.99
Price / CashN/A113.2977.8052.76
Price / Book3.7215.4010.476.32
Net Income-$22.40M-$22.82M$3.49B$359.73M
7 Day Performance-7.41%-1.70%-0.67%0.17%
1 Month Performance-20.45%-6.17%-3.17%-3.27%
1 Year Performance21.53%30.67%15.14%5.58%

Equillium Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
EQ
Equillium
2.3141 of 5 stars
$1.75
-9.3%
$7.57
+332.7%
+24.1%$122.38MN/AN/A14
EIKN
Eikon Therapeutics
3.293 of 5 stars
$8.98
+1.7%
$25.00
+178.4%
N/A$478.28MN/AN/A384
PRTA
Prothena
3.3941 of 5 stars
$8.99
+5.6%
$24.57
+173.3%
+4.5%$445.53M$9.68MN/A67
KYTX
Kyverna Therapeutics
1.4658 of 5 stars
$7.51
+5.5%
$30.00
+299.5%
+12.0%$440.33MN/AN/A149
EDIT
Editas Medicine
2.5051 of 5 stars
$2.92
+3.2%
$6.00
+105.5%
-10.6%$434.63M$40.52MN/A87

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This page (NASDAQ:EQ) was last updated on 9/24/2026 by MarketBeat.com Staff.
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