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Jade Biosciences (JBIO) Competitors

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$14.12 +0.35 (+2.54%)
Closing price 10/2/2026 04:00 PM Eastern
Extended Trading
$14.12 +0.01 (+0.04%)
As of 10/2/2026 07:30 PM Eastern
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JBIO vs. LEGN, XENE, AMLX, ELVN, and DNLI

Should you buy Jade Biosciences stock or one of its competitors? Jade Biosciences's main competitors and comparable companies include Legend Biotech (LEGN), Xenon Pharmaceuticals (XENE), Amylyx Pharmaceuticals (AMLX), Enliven Therapeutics (ELVN), and Denali Therapeutics (DNLI). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Jade Biosciences compare to Legend Biotech?

Legend Biotech (NASDAQ:LEGN) and Jade Biosciences (NASDAQ:JBIO) are both healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their risk, analyst recommendations, valuation, profitability, dividends, earnings, media sentiment and institutional ownership.

70.9% of Legend Biotech shares are owned by institutional investors. 0.0% of Legend Biotech shares are owned by insiders. Comparatively, 23.1% of Jade Biosciences shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

In the previous week, Jade Biosciences had 3 more articles in the media than Legend Biotech. MarketBeat recorded 11 mentions for Jade Biosciences and 8 mentions for Legend Biotech. Legend Biotech's average media sentiment score of 0.33 beat Jade Biosciences' score of 0.26 indicating that Legend Biotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Legend Biotech
3 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Jade Biosciences
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Legend Biotech presently has a consensus target price of $55.79, suggesting a potential upside of 200.41%. Jade Biosciences has a consensus target price of $51.75, suggesting a potential upside of 266.50%. Given Jade Biosciences' stronger consensus rating and higher probable upside, analysts plainly believe Jade Biosciences is more favorable than Legend Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Legend Biotech
1 Sell rating(s)
5 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.53
Jade Biosciences
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.90

Legend Biotech has a beta of 0.57, meaning that its share price is 43% less volatile than the broader market. Comparatively, Jade Biosciences has a beta of 1.64, meaning that its share price is 64% more volatile than the broader market.

Jade Biosciences has lower revenue, but higher earnings than Legend Biotech. Legend Biotech is trading at a lower price-to-earnings ratio than Jade Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Legend Biotech$1.03B3.50-$296.80M-$0.25N/A
Jade BiosciencesN/AN/A-$127.41M-$1.92N/A

Jade Biosciences has a net margin of 0.00% compared to Legend Biotech's net margin of -7.21%. Legend Biotech's return on equity of -8.71% beat Jade Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Legend Biotech-7.21% -8.71% -5.40%
Jade Biosciences N/A -49.11%-45.62%

Summary

Jade Biosciences beats Legend Biotech on 9 of the 16 factors compared between the two stocks.

How does Jade Biosciences compare to Xenon Pharmaceuticals?

Xenon Pharmaceuticals (NASDAQ:XENE) and Jade Biosciences (NASDAQ:JBIO) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, dividends, media sentiment, profitability, valuation, earnings, institutional ownership and risk.

95.4% of Xenon Pharmaceuticals shares are owned by institutional investors. 2.9% of Xenon Pharmaceuticals shares are owned by company insiders. Comparatively, 23.1% of Jade Biosciences shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Xenon Pharmaceuticals' return on equity of -43.98% beat Jade Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Xenon PharmaceuticalsN/A -43.98% -41.72%
Jade Biosciences N/A -49.11%-45.62%

Xenon Pharmaceuticals has a beta of 0.6, meaning that its stock price is 40% less volatile than the broader market. Comparatively, Jade Biosciences has a beta of 1.64, meaning that its stock price is 64% more volatile than the broader market.

Xenon Pharmaceuticals currently has a consensus price target of $70.27, suggesting a potential upside of 84.82%. Jade Biosciences has a consensus price target of $51.75, suggesting a potential upside of 266.50%. Given Jade Biosciences' higher probable upside, analysts clearly believe Jade Biosciences is more favorable than Xenon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xenon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
2.94
Jade Biosciences
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.90

Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Jade Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xenon PharmaceuticalsN/AN/A-$345.91M-$4.74N/A
Jade BiosciencesN/AN/A-$127.41M-$1.92N/A

In the previous week, Xenon Pharmaceuticals and Xenon Pharmaceuticals both had 11 articles in the media. Xenon Pharmaceuticals' average media sentiment score of 1.20 beat Jade Biosciences' score of 0.26 indicating that Xenon Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xenon Pharmaceuticals
6 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Jade Biosciences
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Xenon Pharmaceuticals and Jade Biosciences tied by winning 6 of the 12 factors compared between the two stocks.

How does Jade Biosciences compare to Amylyx Pharmaceuticals?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Jade Biosciences (NASDAQ:JBIO) are both healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their analyst recommendations, profitability, earnings, dividends, media sentiment, valuation, risk and institutional ownership.

In the previous week, Jade Biosciences had 6 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 11 mentions for Jade Biosciences and 5 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 0.99 beat Jade Biosciences' score of 0.26 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Jade Biosciences
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Amylyx Pharmaceuticals presently has a consensus target price of $38.86, suggesting a potential upside of 39.82%. Jade Biosciences has a consensus target price of $51.75, suggesting a potential upside of 266.50%. Given Jade Biosciences' higher possible upside, analysts clearly believe Jade Biosciences is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
3.00
Jade Biosciences
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.90

Jade Biosciences' return on equity of -49.11% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -52.92% -48.53%
Jade Biosciences N/A -49.11%-45.62%

Amylyx Pharmaceuticals has a beta of -0.1, indicating that its stock price is 110% less volatile than the broader market. Comparatively, Jade Biosciences has a beta of 1.64, indicating that its stock price is 64% more volatile than the broader market.

Jade Biosciences has lower revenue, but higher earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Jade Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx Pharmaceuticals$87.37M35.44-$144.74M-$1.43N/A
Jade BiosciencesN/AN/A-$127.41M-$1.92N/A

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are held by insiders. Comparatively, 23.1% of Jade Biosciences shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Summary

Jade Biosciences beats Amylyx Pharmaceuticals on 8 of the 14 factors compared between the two stocks.

How does Jade Biosciences compare to Enliven Therapeutics?

Enliven Therapeutics (NASDAQ:ELVN) and Jade Biosciences (NASDAQ:JBIO) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their profitability, dividends, earnings, media sentiment, valuation, risk, analyst recommendations and institutional ownership.

Enliven Therapeutics has a beta of 0.24, suggesting that its stock price is 76% less volatile than the broader market. Comparatively, Jade Biosciences has a beta of 1.64, suggesting that its stock price is 64% more volatile than the broader market.

Enliven Therapeutics' return on equity of -18.55% beat Jade Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Enliven TherapeuticsN/A -18.55% -18.09%
Jade Biosciences N/A -49.11%-45.62%

95.1% of Enliven Therapeutics shares are held by institutional investors. 3.0% of Enliven Therapeutics shares are held by company insiders. Comparatively, 23.1% of Jade Biosciences shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

In the previous week, Jade Biosciences had 7 more articles in the media than Enliven Therapeutics. MarketBeat recorded 11 mentions for Jade Biosciences and 4 mentions for Enliven Therapeutics. Enliven Therapeutics' average media sentiment score of 1.12 beat Jade Biosciences' score of 0.26 indicating that Enliven Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Enliven Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Jade Biosciences
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Enliven Therapeutics is trading at a lower price-to-earnings ratio than Jade Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Enliven TherapeuticsN/AN/A-$103.69M-$1.67N/A
Jade BiosciencesN/AN/A-$127.41M-$1.92N/A

Enliven Therapeutics currently has a consensus price target of $74.44, indicating a potential upside of 58.49%. Jade Biosciences has a consensus price target of $51.75, indicating a potential upside of 266.50%. Given Jade Biosciences' stronger consensus rating and higher possible upside, analysts plainly believe Jade Biosciences is more favorable than Enliven Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Enliven Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Jade Biosciences
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.90

Summary

Enliven Therapeutics and Jade Biosciences tied by winning 7 of the 14 factors compared between the two stocks.

How does Jade Biosciences compare to Denali Therapeutics?

Denali Therapeutics (NASDAQ:DNLI) and Jade Biosciences (NASDAQ:JBIO) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their earnings, institutional ownership, profitability, media sentiment, analyst recommendations, risk, dividends and valuation.

In the previous week, Jade Biosciences had 9 more articles in the media than Denali Therapeutics. MarketBeat recorded 11 mentions for Jade Biosciences and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 0.45 beat Jade Biosciences' score of 0.26 indicating that Denali Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Denali Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Jade Biosciences
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Denali Therapeutics has a beta of 1.02, meaning that its stock price is 2% more volatile than the broader market. Comparatively, Jade Biosciences has a beta of 1.64, meaning that its stock price is 64% more volatile than the broader market.

Jade Biosciences has lower revenue, but higher earnings than Denali Therapeutics. Jade Biosciences is trading at a lower price-to-earnings ratio than Denali Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Denali Therapeutics$3.60M887.05-$512.54M-$2.84N/A
Jade BiosciencesN/AN/A-$127.41M-$1.92N/A

92.9% of Denali Therapeutics shares are held by institutional investors. 9.7% of Denali Therapeutics shares are held by company insiders. Comparatively, 23.1% of Jade Biosciences shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Denali Therapeutics presently has a consensus target price of $35.85, suggesting a potential upside of 79.23%. Jade Biosciences has a consensus target price of $51.75, suggesting a potential upside of 266.50%. Given Jade Biosciences' stronger consensus rating and higher probable upside, analysts plainly believe Jade Biosciences is more favorable than Denali Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Denali Therapeutics
1 Sell rating(s)
2 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.75
Jade Biosciences
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.90

Jade Biosciences' return on equity of -49.11% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Denali TherapeuticsN/A -55.27% -44.24%
Jade Biosciences N/A -49.11%-45.62%

Summary

Jade Biosciences beats Denali Therapeutics on 9 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding JBIO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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JBIO vs. The Competition

MetricJade BiosciencesBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$897.99M$3.86B$7.16B$13.28B
Dividend YieldN/A3.65%2.54%17.32%
P/E Ratio-7.3513.06275.6626.04
Price / SalesN/A1,295.79609.4691.89
Price / CashN/A123.3978.8752.62
Price / Book2.0916.6310.936.31
Net Income-$127.41M-$22.71M$3.51B$362.16M
7 Day Performance-2.08%-2.99%-2.00%-1.66%
1 Month Performance-28.87%-10.60%-6.15%-4.50%
1 Year Performance59.37%19.44%7.44%2.06%

Jade Biosciences Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
JBIO
Jade Biosciences
2.0056 of 5 stars
$14.12
+2.5%
$51.75
+266.5%
+69.5%$897.99MN/AN/A55
LEGN
Legend Biotech
3.5577 of 5 stars
$19.06
+3.3%
$53.14
+178.8%
-42.5%$3.69B$1.27BN/A2,965
XENE
Xenon Pharmaceuticals
3.802 of 5 stars
$38.06
+4.1%
$70.93
+86.4%
-3.0%$3.68B$7.50MN/A370
AMLX
Amylyx Pharmaceuticals
3.3871 of 5 stars
$30.14
-1.5%
$38.86
+28.9%
+109.1%$3.36BN/AN/A136
ELVN
Enliven Therapeutics
2.9041 of 5 stars
$45.17
-2.0%
$75.00
+66.0%
+135.8%$3.31BN/AN/A67

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This page (NASDAQ:JBIO) was last updated on 10/3/2026 by MarketBeat.com Staff.
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