Lyell Immunopharma (LYEL) Competitors $10.76 +0.11 (+1.03%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$10.70 -0.06 (-0.60%) As of 08/22/2025 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock LYEL vs. ABUS, DNTH, PROK, TSHA, GHRS, DAWN, MGTX, ORGO, KALV, and VIRShould you be buying Lyell Immunopharma stock or one of its competitors? The main competitors of Lyell Immunopharma include Arbutus Biopharma (ABUS), Dianthus Therapeutics (DNTH), ProKidney (PROK), Taysha Gene Therapies (TSHA), GH Research (GHRS), Day One Biopharmaceuticals (DAWN), MeiraGTx (MGTX), Organogenesis (ORGO), KalVista Pharmaceuticals (KALV), and Vir Biotechnology (VIR). These companies are all part of the "pharmaceutical products" industry. Lyell Immunopharma vs. Its Competitors Arbutus Biopharma Dianthus Therapeutics ProKidney Taysha Gene Therapies GH Research Day One Biopharmaceuticals MeiraGTx Organogenesis KalVista Pharmaceuticals Vir Biotechnology Arbutus Biopharma (NASDAQ:ABUS) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, risk, analyst recommendations, profitability, valuation, dividends, institutional ownership and media sentiment. Which has preferable valuation & earnings, ABUS or LYEL? Arbutus Biopharma has higher revenue and earnings than Lyell Immunopharma. Arbutus Biopharma is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioArbutus Biopharma$6.17M111.54-$69.92M-$0.29-12.38Lyell Immunopharma$60K3,444.99-$342.99M-$24.29-0.44 Do institutionals and insiders hold more shares of ABUS or LYEL? 43.8% of Arbutus Biopharma shares are owned by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are owned by institutional investors. 20.3% of Arbutus Biopharma shares are owned by insiders. Comparatively, 22.3% of Lyell Immunopharma shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Do analysts prefer ABUS or LYEL? Arbutus Biopharma currently has a consensus target price of $5.50, suggesting a potential upside of 53.20%. Lyell Immunopharma has a consensus target price of $15.00, suggesting a potential upside of 39.41%. Given Arbutus Biopharma's stronger consensus rating and higher possible upside, equities analysts plainly believe Arbutus Biopharma is more favorable than Lyell Immunopharma.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Arbutus Biopharma 0 Sell rating(s) 0 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 3.00Lyell Immunopharma 1 Sell rating(s) 1 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 1.50 Which has more risk & volatility, ABUS or LYEL? Arbutus Biopharma has a beta of 0.86, suggesting that its share price is 14% less volatile than the S&P 500. Comparatively, Lyell Immunopharma has a beta of -0.19, suggesting that its share price is 119% less volatile than the S&P 500. Does the media refer more to ABUS or LYEL? In the previous week, Arbutus Biopharma and Arbutus Biopharma both had 1 articles in the media. Lyell Immunopharma's average media sentiment score of 1.36 beat Arbutus Biopharma's score of 1.23 indicating that Lyell Immunopharma is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Arbutus Biopharma 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Lyell Immunopharma 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is ABUS or LYEL more profitable? Arbutus Biopharma has a net margin of -352.24% compared to Lyell Immunopharma's net margin of -552,328.31%. Arbutus Biopharma's return on equity of -59.28% beat Lyell Immunopharma's return on equity.Company Net Margins Return on Equity Return on Assets Arbutus Biopharma-352.24% -59.28% -44.11% Lyell Immunopharma -552,328.31%-85.58%-68.85% SummaryArbutus Biopharma beats Lyell Immunopharma on 10 of the 15 factors compared between the two stocks. Get Lyell Immunopharma News Delivered to You Automatically Sign up to receive the latest news and ratings for LYEL and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding LYEL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart LYEL vs. The Competition Export to ExcelMetricLyell ImmunopharmaMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$204.60M$2.56B$5.76B$9.61BDividend YieldN/A1.67%4.41%4.10%P/E Ratio-0.4422.6131.1026.04Price / Sales3,444.99555.44436.34104.14Price / CashN/A180.4637.7358.48Price / Book0.695.939.536.61Net Income-$342.99M$31.83M$3.26B$265.56M7 Day Performance1.70%1.89%2.10%1.95%1 Month Performance-2.09%1.33%2.81%-0.37%1 Year Performance-65.51%8.84%30.56%19.02% Lyell Immunopharma Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)LYELLyell Immunopharma3.7528 of 5 stars$10.76+1.0%$15.00+39.4%-62.9%$204.60M$60K-0.44270Positive NewsABUSArbutus Biopharma2.7435 of 5 stars$3.36+0.1%$5.50+63.9%-5.8%$645.07M$6.17M-11.6090News CoverageDNTHDianthus Therapeutics1.0592 of 5 stars$20.05+6.1%$53.00+164.4%-12.0%$643.04M$6.24M-6.1580Analyst ForecastAnalyst RevisionPROKProKidney3.7354 of 5 stars$2.19-3.3%$6.25+186.0%+10.6%$642.48M$80K-3.663News CoverageShort Interest ↓TSHATaysha Gene Therapies3.4032 of 5 stars$2.93+6.0%$8.17+179.2%+33.9%$632.17M$8.33M-8.66180GHRSGH Research2.7072 of 5 stars$11.99+1.6%$32.00+167.0%+17.7%$623.32MN/A-16.1910Positive NewsDAWNDay One Biopharmaceuticals2.2699 of 5 stars$6.07+2.8%$25.33+317.7%-47.4%$622.26M$131.16M-6.3960News CoverageInsider TradeMGTXMeiraGTx4.4292 of 5 stars$7.71-1.6%$24.00+211.2%+89.6%$619.82M$33.28M-3.32300ORGOOrganogenesis4.2954 of 5 stars$4.85+5.1%$7.50+54.8%+77.8%$617.17M$482.04M-34.75950KALVKalVista Pharmaceuticals4.0149 of 5 stars$12.32-1.5%$26.29+113.3%+8.0%$616.28MN/A-3.34100VIRVir Biotechnology3.428 of 5 stars$4.36+1.8%$30.25+594.6%-45.0%$606.25M$74.21M-1.09580Positive News Related Companies and Tools Related Companies ABUS Alternatives DNTH Alternatives PROK Alternatives TSHA Alternatives GHRS Alternatives DAWN Alternatives MGTX Alternatives ORGO Alternatives KALV Alternatives VIR Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:LYEL) was last updated on 8/23/2025 by MarketBeat.com Staff From Our PartnersBONUS GUIDE - Ben Stein Prepares For the Next Financial CrisisWith inflation high, debt soaring, and global tensions rising, a financial storm may be brewing. 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