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Maze Therapeutics (MAZE) Competitors

Maze Therapeutics logo
$29.43 +0.50 (+1.73%)
As of 08/21/2026 04:00 PM Eastern

MAZE vs. XENE, KNSA, PTCT, LGND, and TVTX

Should you buy Maze Therapeutics stock or one of its competitors? Maze Therapeutics's main competitors and comparable companies include Xenon Pharmaceuticals (XENE), Kiniksa Pharmaceuticals International (KNSA), PTC Therapeutics (PTCT), Ligand Pharmaceuticals (LGND), and Travere Therapeutics (TVTX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Maze Therapeutics compare to Xenon Pharmaceuticals?

Xenon Pharmaceuticals (NASDAQ:XENE) and Maze Therapeutics (NASDAQ:MAZE) are both healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their valuation, risk, analyst recommendations, earnings, dividends, media sentiment, profitability and institutional ownership.

In the previous week, Xenon Pharmaceuticals and Xenon Pharmaceuticals both had 4 articles in the media. Xenon Pharmaceuticals' average media sentiment score of 1.24 beat Maze Therapeutics' score of 1.21 indicating that Xenon Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xenon Pharmaceuticals
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Maze Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Maze Therapeutics has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Maze Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xenon Pharmaceuticals$7.50M783.28-$345.91M-$4.74N/A
Maze Therapeutics$167.50M9.76-$131.12M-$2.52N/A

Xenon Pharmaceuticals has a beta of 0.62, meaning that its stock price is 38% less volatile than the broader market. Comparatively, Maze Therapeutics has a beta of 2.21, meaning that its stock price is 121% more volatile than the broader market.

95.5% of Xenon Pharmaceuticals shares are held by institutional investors. 2.9% of Xenon Pharmaceuticals shares are held by company insiders. Comparatively, 5.3% of Maze Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Maze Therapeutics' return on equity of -34.94% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Xenon PharmaceuticalsN/A -43.98% -41.72%
Maze Therapeutics N/A -34.94%-30.18%

Xenon Pharmaceuticals currently has a consensus price target of $77.13, indicating a potential upside of 26.93%. Maze Therapeutics has a consensus price target of $66.00, indicating a potential upside of 124.26%. Given Maze Therapeutics' higher possible upside, analysts clearly believe Maze Therapeutics is more favorable than Xenon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

Maze Therapeutics beats Xenon Pharmaceuticals on 9 of the 13 factors compared between the two stocks.

How does Maze Therapeutics compare to Kiniksa Pharmaceuticals International?

Maze Therapeutics (NASDAQ:MAZE) and Kiniksa Pharmaceuticals International (NASDAQ:KNSA) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their risk, analyst recommendations, earnings, institutional ownership, valuation, dividends, profitability and media sentiment.

Maze Therapeutics has a beta of 2.21, meaning that its share price is 121% more volatile than the broader market. Comparatively, Kiniksa Pharmaceuticals International has a beta of 0.05, meaning that its share price is 95% less volatile than the broader market.

54.0% of Kiniksa Pharmaceuticals International shares are held by institutional investors. 5.3% of Maze Therapeutics shares are held by company insiders. Comparatively, 52.0% of Kiniksa Pharmaceuticals International shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Kiniksa Pharmaceuticals International has a net margin of 9.59% compared to Maze Therapeutics' net margin of 0.00%. Kiniksa Pharmaceuticals International's return on equity of 13.65% beat Maze Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Maze TherapeuticsN/A -34.94% -30.18%
Kiniksa Pharmaceuticals International 9.59%13.65%10.09%

Kiniksa Pharmaceuticals International has higher revenue and earnings than Maze Therapeutics. Maze Therapeutics is trading at a lower price-to-earnings ratio than Kiniksa Pharmaceuticals International, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Maze Therapeutics$167.50M9.76-$131.12M-$2.52N/A
Kiniksa Pharmaceuticals International$677.56M9.10$59.01M$0.9781.47

In the previous week, Maze Therapeutics had 3 more articles in the media than Kiniksa Pharmaceuticals International. MarketBeat recorded 4 mentions for Maze Therapeutics and 1 mentions for Kiniksa Pharmaceuticals International. Kiniksa Pharmaceuticals International's average media sentiment score of 1.63 beat Maze Therapeutics' score of 1.21 indicating that Kiniksa Pharmaceuticals International is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Maze Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Kiniksa Pharmaceuticals International
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Maze Therapeutics currently has a consensus target price of $66.00, suggesting a potential upside of 124.26%. Kiniksa Pharmaceuticals International has a consensus target price of $87.38, suggesting a potential upside of 10.56%. Given Maze Therapeutics' stronger consensus rating and higher probable upside, equities analysts plainly believe Maze Therapeutics is more favorable than Kiniksa Pharmaceuticals International.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00
Kiniksa Pharmaceuticals International
0 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.80

Summary

Kiniksa Pharmaceuticals International beats Maze Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Maze Therapeutics compare to PTC Therapeutics?

Maze Therapeutics (NASDAQ:MAZE) and PTC Therapeutics (NASDAQ:PTCT) are both healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their valuation, earnings, profitability, risk, institutional ownership, media sentiment, analyst recommendations and dividends.

PTC Therapeutics has higher revenue and earnings than Maze Therapeutics. PTC Therapeutics is trading at a lower price-to-earnings ratio than Maze Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Maze Therapeutics$167.50M9.76-$131.12M-$2.52N/A
PTC Therapeutics$1.01B5.78$682.64M-$0.58N/A

In the previous week, PTC Therapeutics had 10 more articles in the media than Maze Therapeutics. MarketBeat recorded 14 mentions for PTC Therapeutics and 4 mentions for Maze Therapeutics. Maze Therapeutics' average media sentiment score of 1.21 beat PTC Therapeutics' score of 0.77 indicating that Maze Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Maze Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
PTC Therapeutics
8 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Maze Therapeutics has a beta of 2.21, meaning that its stock price is 121% more volatile than the broader market. Comparatively, PTC Therapeutics has a beta of 0.56, meaning that its stock price is 44% less volatile than the broader market.

Maze Therapeutics currently has a consensus price target of $66.00, suggesting a potential upside of 124.26%. PTC Therapeutics has a consensus price target of $98.55, suggesting a potential upside of 41.14%. Given Maze Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Maze Therapeutics is more favorable than PTC Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00
PTC Therapeutics
2 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.64

Maze Therapeutics has a net margin of 0.00% compared to PTC Therapeutics' net margin of -3.80%. Maze Therapeutics' return on equity of -34.94% beat PTC Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Maze TherapeuticsN/A -34.94% -30.18%
PTC Therapeutics -3.80%-362.45%-1.32%

Summary

Maze Therapeutics beats PTC Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Maze Therapeutics compare to Ligand Pharmaceuticals?

Maze Therapeutics (NASDAQ:MAZE) and Ligand Pharmaceuticals (NASDAQ:LGND) are both healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, valuation, analyst recommendations, media sentiment, risk, dividends, profitability and institutional ownership.

Maze Therapeutics currently has a consensus price target of $66.00, indicating a potential upside of 124.26%. Ligand Pharmaceuticals has a consensus price target of $335.75, indicating a potential upside of 17.28%. Given Maze Therapeutics' higher probable upside, equities analysts clearly believe Maze Therapeutics is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00
Ligand Pharmaceuticals
0 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
3.00

Ligand Pharmaceuticals has a net margin of 67.88% compared to Maze Therapeutics' net margin of 0.00%. Ligand Pharmaceuticals' return on equity of 20.06% beat Maze Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Maze TherapeuticsN/A -34.94% -30.18%
Ligand Pharmaceuticals 67.88%20.06%11.68%

In the previous week, Maze Therapeutics and Maze Therapeutics both had 4 articles in the media. Maze Therapeutics' average media sentiment score of 1.21 beat Ligand Pharmaceuticals' score of 0.40 indicating that Maze Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Maze Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ligand Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Ligand Pharmaceuticals has higher revenue and earnings than Maze Therapeutics. Maze Therapeutics is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Maze Therapeutics$167.50M9.76-$131.12M-$2.52N/A
Ligand Pharmaceuticals$268.09M21.29$124.45M$9.3530.62

Maze Therapeutics has a beta of 2.21, suggesting that its share price is 121% more volatile than the broader market. Comparatively, Ligand Pharmaceuticals has a beta of 1.13, suggesting that its share price is 13% more volatile than the broader market.

91.3% of Ligand Pharmaceuticals shares are held by institutional investors. 5.3% of Maze Therapeutics shares are held by insiders. Comparatively, 5.6% of Ligand Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Summary

Ligand Pharmaceuticals beats Maze Therapeutics on 11 of the 15 factors compared between the two stocks.

How does Maze Therapeutics compare to Travere Therapeutics?

Travere Therapeutics (NASDAQ:TVTX) and Maze Therapeutics (NASDAQ:MAZE) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their analyst recommendations, institutional ownership, earnings, dividends, media sentiment, profitability, risk and valuation.

Travere Therapeutics has higher revenue and earnings than Maze Therapeutics. Travere Therapeutics is trading at a lower price-to-earnings ratio than Maze Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Travere Therapeutics$490.73M12.62-$25.55M-$0.46N/A
Maze Therapeutics$167.50M9.76-$131.12M-$2.52N/A

Maze Therapeutics has a net margin of 0.00% compared to Travere Therapeutics' net margin of -7.35%. Maze Therapeutics' return on equity of -34.94% beat Travere Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Travere Therapeutics-7.35% -55.15% -6.88%
Maze Therapeutics N/A -34.94%-30.18%

In the previous week, Travere Therapeutics had 7 more articles in the media than Maze Therapeutics. MarketBeat recorded 11 mentions for Travere Therapeutics and 4 mentions for Maze Therapeutics. Maze Therapeutics' average media sentiment score of 1.21 beat Travere Therapeutics' score of 1.18 indicating that Maze Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Travere Therapeutics
8 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Maze Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Travere Therapeutics has a beta of 1.12, meaning that its share price is 12% more volatile than the broader market. Comparatively, Maze Therapeutics has a beta of 2.21, meaning that its share price is 121% more volatile than the broader market.

Travere Therapeutics currently has a consensus price target of $61.67, indicating a potential downside of 6.15%. Maze Therapeutics has a consensus price target of $66.00, indicating a potential upside of 124.26%. Given Maze Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Maze Therapeutics is more favorable than Travere Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Travere Therapeutics
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.69
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

Maze Therapeutics beats Travere Therapeutics on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding MAZE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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MAZE vs. The Competition

MetricMaze TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.63B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-11.6811.62272.6024.24
Price / Sales9.761,338.17618.9699.78
Price / CashN/A105.1478.6253.99
Price / Book3.6116.8013.056.20
Net Income-$131.12M-$12.50M$3.47B$348.59M
7 Day Performance8.28%3.29%2.09%0.08%
1 Month Performance6.28%8.23%6.64%3.88%
1 Year Performance118.16%55.05%25.02%16.98%

Maze Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
MAZE
Maze Therapeutics
2.129 of 5 stars
$29.43
+1.7%
$66.00
+124.3%
+118.2%$1.63B$167.50MN/A121
XENE
Xenon Pharmaceuticals
3.3921 of 5 stars
$62.35
-2.9%
$77.13
+23.7%
+56.5%$6.03B$7.50MN/A210
KNSA
Kiniksa Pharmaceuticals International
3.9637 of 5 stars
$76.75
-1.4%
$87.38
+13.8%
+134.2%$5.99B$677.56M79.12220
PTCT
PTC Therapeutics
3.8008 of 5 stars
$71.70
-0.4%
$98.55
+37.4%
+38.1%$5.98B$1.73BN/A1,410
LGND
Ligand Pharmaceuticals
3.7464 of 5 stars
$294.60
+2.0%
$335.75
+14.0%
+80.0%$5.87B$290.54M31.5180

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This page (NASDAQ:MAZE) was last updated on 8/23/2026 by MarketBeat.com Staff.
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