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Maze Therapeutics (MAZE) Competitors

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$24.60 -0.22 (-0.89%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$24.65 +0.05 (+0.20%)
As of 09/11/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

MAZE vs. PTCT, XENE, LGND, ERAS, and CRSP

Should you buy Maze Therapeutics stock or one of its competitors? Maze Therapeutics's main competitors and comparable companies include PTC Therapeutics (PTCT), Xenon Pharmaceuticals (XENE), Ligand Pharmaceuticals (LGND), Erasca (ERAS), and CRISPR Therapeutics (CRSP). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Maze Therapeutics compare to PTC Therapeutics?

Maze Therapeutics (NASDAQ:MAZE) and PTC Therapeutics (NASDAQ:PTCT) are both healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their earnings, risk, analyst recommendations, media sentiment, dividends, institutional ownership, valuation and profitability.

In the previous week, Maze Therapeutics had 3 more articles in the media than PTC Therapeutics. MarketBeat recorded 9 mentions for Maze Therapeutics and 6 mentions for PTC Therapeutics. PTC Therapeutics' average media sentiment score of 1.23 beat Maze Therapeutics' score of 0.45 indicating that PTC Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Maze Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
PTC Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Maze Therapeutics presently has a consensus price target of $66.00, indicating a potential upside of 168.29%. PTC Therapeutics has a consensus price target of $98.55, indicating a potential upside of 49.18%. Given Maze Therapeutics' stronger consensus rating and higher probable upside, equities research analysts clearly believe Maze Therapeutics is more favorable than PTC Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
3 Strong Buy rating(s)
3.08
PTC Therapeutics
2 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.64

Maze Therapeutics has a beta of 2.17, meaning that its share price is 117% more volatile than the broader market. Comparatively, PTC Therapeutics has a beta of 0.55, meaning that its share price is 45% less volatile than the broader market.

PTC Therapeutics has higher revenue and earnings than Maze Therapeutics. PTC Therapeutics is trading at a lower price-to-earnings ratio than Maze Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Maze Therapeutics$167.50M8.16-$131.12M-$2.52N/A
PTC Therapeutics$1.73B3.19$682.64M-$0.58N/A

Maze Therapeutics has a net margin of 0.00% compared to PTC Therapeutics' net margin of -3.80%. Maze Therapeutics' return on equity of -34.94% beat PTC Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Maze TherapeuticsN/A -34.94% -30.18%
PTC Therapeutics -3.80%-362.45%-1.32%

Summary

Maze Therapeutics beats PTC Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Maze Therapeutics compare to Xenon Pharmaceuticals?

Maze Therapeutics (NASDAQ:MAZE) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their profitability, media sentiment, institutional ownership, risk, valuation, dividends, earnings and analyst recommendations.

Maze Therapeutics has a beta of 2.17, suggesting that its stock price is 117% more volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.61, suggesting that its stock price is 39% less volatile than the broader market.

Maze Therapeutics currently has a consensus price target of $66.00, suggesting a potential upside of 168.29%. Xenon Pharmaceuticals has a consensus price target of $77.13, suggesting a potential upside of 31.51%. Given Maze Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Maze Therapeutics is more favorable than Xenon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
3 Strong Buy rating(s)
3.08
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00

In the previous week, Maze Therapeutics had 2 more articles in the media than Xenon Pharmaceuticals. MarketBeat recorded 9 mentions for Maze Therapeutics and 7 mentions for Xenon Pharmaceuticals. Xenon Pharmaceuticals' average media sentiment score of 1.07 beat Maze Therapeutics' score of 0.45 indicating that Xenon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Maze Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Xenon Pharmaceuticals
3 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Maze Therapeutics has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Maze Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Maze Therapeutics$167.50M8.16-$131.12M-$2.52N/A
Xenon Pharmaceuticals$7.50M755.96-$345.91M-$4.74N/A

Maze Therapeutics' return on equity of -34.94% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Maze TherapeuticsN/A -34.94% -30.18%
Xenon Pharmaceuticals N/A -43.98%-41.72%

95.5% of Xenon Pharmaceuticals shares are held by institutional investors. 5.3% of Maze Therapeutics shares are held by company insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Summary

Maze Therapeutics beats Xenon Pharmaceuticals on 12 of the 16 factors compared between the two stocks.

How does Maze Therapeutics compare to Ligand Pharmaceuticals?

Ligand Pharmaceuticals (NASDAQ:LGND) and Maze Therapeutics (NASDAQ:MAZE) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, analyst recommendations, media sentiment, profitability, institutional ownership, earnings, valuation and dividends.

Ligand Pharmaceuticals has a net margin of 67.88% compared to Maze Therapeutics' net margin of 0.00%. Ligand Pharmaceuticals' return on equity of 20.06% beat Maze Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Ligand Pharmaceuticals67.88% 20.06% 11.68%
Maze Therapeutics N/A -34.94%-30.18%

Ligand Pharmaceuticals has higher revenue and earnings than Maze Therapeutics. Maze Therapeutics is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ligand Pharmaceuticals$268.09M21.16$124.45M$9.3530.42
Maze Therapeutics$167.50M8.16-$131.12M-$2.52N/A

Ligand Pharmaceuticals has a beta of 1.11, suggesting that its stock price is 11% more volatile than the broader market. Comparatively, Maze Therapeutics has a beta of 2.17, suggesting that its stock price is 117% more volatile than the broader market.

In the previous week, Maze Therapeutics had 1 more articles in the media than Ligand Pharmaceuticals. MarketBeat recorded 9 mentions for Maze Therapeutics and 8 mentions for Ligand Pharmaceuticals. Ligand Pharmaceuticals' average media sentiment score of 1.33 beat Maze Therapeutics' score of 0.45 indicating that Ligand Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ligand Pharmaceuticals
6 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Maze Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

91.3% of Ligand Pharmaceuticals shares are owned by institutional investors. 5.6% of Ligand Pharmaceuticals shares are owned by company insiders. Comparatively, 5.3% of Maze Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Ligand Pharmaceuticals presently has a consensus target price of $335.75, indicating a potential upside of 18.03%. Maze Therapeutics has a consensus target price of $66.00, indicating a potential upside of 168.29%. Given Maze Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Maze Therapeutics is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ligand Pharmaceuticals
0 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
3.00
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
3 Strong Buy rating(s)
3.08

Summary

Ligand Pharmaceuticals beats Maze Therapeutics on 12 of the 17 factors compared between the two stocks.

How does Maze Therapeutics compare to Erasca?

Erasca (NASDAQ:ERAS) and Maze Therapeutics (NASDAQ:MAZE) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, analyst recommendations, profitability, dividends, institutional ownership, earnings, media sentiment and valuation.

Erasca has a beta of 0.64, suggesting that its share price is 36% less volatile than the broader market. Comparatively, Maze Therapeutics has a beta of 2.17, suggesting that its share price is 117% more volatile than the broader market.

In the previous week, Erasca and Erasca both had 9 articles in the media. Erasca's average media sentiment score of 1.11 beat Maze Therapeutics' score of 0.45 indicating that Erasca is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Erasca
4 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Maze Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Erasca currently has a consensus price target of $22.09, indicating a potential upside of 39.11%. Maze Therapeutics has a consensus price target of $66.00, indicating a potential upside of 168.29%. Given Maze Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Maze Therapeutics is more favorable than Erasca.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Erasca
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.64
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
3 Strong Buy rating(s)
3.08

67.8% of Erasca shares are owned by institutional investors. 14.2% of Erasca shares are owned by insiders. Comparatively, 5.3% of Maze Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Maze Therapeutics' return on equity of -34.94% beat Erasca's return on equity.

Company Net Margins Return on Equity Return on Assets
ErascaN/A -38.43% -32.05%
Maze Therapeutics N/A -34.94%-30.18%

Erasca has higher earnings, but lower revenue than Maze Therapeutics. Erasca is trading at a lower price-to-earnings ratio than Maze Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ErascaN/AN/A-$124.55M-$0.95N/A
Maze Therapeutics$167.50M8.16-$131.12M-$2.52N/A

Summary

Maze Therapeutics beats Erasca on 8 of the 13 factors compared between the two stocks.

How does Maze Therapeutics compare to CRISPR Therapeutics?

Maze Therapeutics (NASDAQ:MAZE) and CRISPR Therapeutics (NASDAQ:CRSP) are both healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, analyst recommendations, institutional ownership, media sentiment, dividends, profitability, valuation and risk.

Maze Therapeutics has a net margin of 0.00% compared to CRISPR Therapeutics' net margin of -3,368.72%. CRISPR Therapeutics' return on equity of -24.39% beat Maze Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Maze TherapeuticsN/A -34.94% -30.18%
CRISPR Therapeutics -3,368.72%-24.39%-18.25%

Maze Therapeutics currently has a consensus target price of $66.00, indicating a potential upside of 168.29%. CRISPR Therapeutics has a consensus target price of $68.06, indicating a potential upside of 31.58%. Given Maze Therapeutics' stronger consensus rating and higher possible upside, equities analysts plainly believe Maze Therapeutics is more favorable than CRISPR Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
3 Strong Buy rating(s)
3.08
CRISPR Therapeutics
1 Sell rating(s)
6 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.61

In the previous week, Maze Therapeutics had 1 more articles in the media than CRISPR Therapeutics. MarketBeat recorded 9 mentions for Maze Therapeutics and 8 mentions for CRISPR Therapeutics. CRISPR Therapeutics' average media sentiment score of 0.85 beat Maze Therapeutics' score of 0.45 indicating that CRISPR Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Maze Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
CRISPR Therapeutics
1 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

69.2% of CRISPR Therapeutics shares are held by institutional investors. 5.3% of Maze Therapeutics shares are held by insiders. Comparatively, 5.2% of CRISPR Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Maze Therapeutics has a beta of 2.17, suggesting that its stock price is 117% more volatile than the broader market. Comparatively, CRISPR Therapeutics has a beta of 1.76, suggesting that its stock price is 76% more volatile than the broader market.

Maze Therapeutics has higher revenue and earnings than CRISPR Therapeutics. CRISPR Therapeutics is trading at a lower price-to-earnings ratio than Maze Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Maze Therapeutics$167.50M8.16-$131.12M-$2.52N/A
CRISPR Therapeutics$3.51M1,424.73-$581.60M-$4.76N/A

Summary

Maze Therapeutics beats CRISPR Therapeutics on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding MAZE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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MAZE vs. The Competition

MetricMaze TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.37B$3.86B$7.17B$12.85B
Dividend YieldN/A3.66%2.57%11.71%
P/E Ratio-9.768.38214.5720.80
Price / Sales8.161,378.81633.7690.54
Price / CashN/A106.5076.6551.52
Price / Book3.3315.1210.336.20
Net Income-$131.12M-$22.86M$3.50B$358.50M
7 Day Performance-6.14%-4.34%-3.32%-2.35%
1 Month Performance-10.64%-0.02%-0.41%-2.77%
1 Year Performance5.58%40.64%19.21%7.63%

Maze Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
MAZE
Maze Therapeutics
2.4441 of 5 stars
$24.60
-0.9%
$66.00
+168.3%
-0.8%$1.37B$167.50MN/A141
PTCT
PTC Therapeutics
3.7602 of 5 stars
$69.30
-2.9%
$98.55
+42.2%
+8.4%$5.78B$1.73BN/A1,410
XENE
Xenon Pharmaceuticals
2.5197 of 5 stars
$59.75
-1.1%
$77.13
+29.1%
+57.6%$5.78B$7.50MN/A210
LGND
Ligand Pharmaceuticals
3.9676 of 5 stars
$285.60
-1.4%
$335.75
+17.6%
+70.3%$5.69B$290.54M30.5580
ERAS
Erasca
2.427 of 5 stars
$16.19
-0.4%
$22.09
+36.4%
+886.3%$5.66BN/AN/A120

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This page (NASDAQ:MAZE) was last updated on 9/12/2026 by MarketBeat.com Staff.
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