| 5/16/2025 | Woodline Partners LP | 100,204 | $1.19M | 0.0% | -70.4% | 0.131% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 507,471 | $6.03M | 0.0% | +9.5% | 0.666% | |
| 5/16/2025 | Parkman Healthcare Partners LLC | 350,420 | $4.16M | 0.5% | -34.2% | 0.460% | |
| 5/16/2025 | Millennium Management LLC | 874,399 | $10.39M | 0.0% | +106.2% | 1.147% | |
| 5/16/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 49,804 | $593K | 0.0% | +11.9% | 0.065% | |
| 5/16/2025 | Cinctive Capital Management LP | 38,770 | $461K | 0.0% | -75.6% | 0.051% | |
| 5/16/2025 | AQR Capital Management LLC | 11,668 | $139K | 0.0% | -83.5% | 0.015% | |
| 5/16/2025 | ADAR1 Capital Management LLC | 21,200 | $252K | 0.0% | +92.7% | 0.028% | |
| 5/15/2025 | Redmile Group LLC | 4,051,927 | $48.14M | 4.5% | -3.4% | 5.315% | |
| 5/15/2025 | Vestal Point Capital LP | 1,125,552 | $13.37M | 1.0% | +132.1% | 1.476% | |
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| 5/15/2025 | Cubist Systematic Strategies LLC | 117,615 | $1.40M | 0.0% | -5.2% | 0.154% | |
| 5/15/2025 | Driehaus Capital Management LLC | 715,940 | $8.51M | 0.1% | -44.1% | 0.939% | |
| 5/15/2025 | Tema Etfs LLC | 59,146 | $703K | 0.2% | +162.2% | 0.078% | |
| 5/14/2025 | Affinity Asset Advisors LLC | 810,669 | $9.63M | 0.9% | -13.8% | 1.063% | |
| 5/14/2025 | Rafferty Asset Management LLC | 110,082 | $1.31M | 0.0% | -5.3% | 0.144% | |
| 5/14/2025 | Corebridge Financial Inc. | 36,849 | $438K | 0.0% | +5.6% | 0.048% | |
| 5/14/2025 | Walleye Capital LLC | 74,060 | $880K | 0.0% | N/A | 0.097% | |
| 5/14/2025 | Jump Financial LLC | 76,060 | $904K | 0.0% | +1.9% | 0.100% | |
| 5/14/2025 | AlphaQuest LLC | 2,572 | $31K | 0.0% | -63.2% | 0.003% | |
| 5/14/2025 | Candriam S.C.A. | 588,931 | $7.00M | 0.0% | -7.2% | 0.773% | |
| 5/14/2025 | T. Rowe Price Investment Management Inc. | 2,428,283 | $28.85M | 0.0% | +2.0% | 3.185% | |
| 5/14/2025 | EntryPoint Capital LLC | 37,559 | $446K | 0.2% | +166.3% | 0.049% | |
| 5/14/2025 | Hsbc Holdings PLC | 16,095 | $189K | 0.0% | +32.9% | 0.021% | |
| 5/14/2025 | Wellington Management Group LLP | 3,188,742 | $37.88M | 0.0% | -11.1% | 4.183% | |
| 5/13/2025 | E Fund Management Co. Ltd. | 10,288 | $122K | 0.0% | N/A | 0.013% | |
| 5/13/2025 | Russell Investments Group Ltd. | 129,738 | $1.54M | 0.0% | +263.0% | 0.170% | |
| 5/12/2025 | Nuveen LLC | 169,145 | $2.01M | 0.0% | N/A | 0.222% | |
| 5/12/2025 | Invesco Ltd. | 117,635 | $1.40M | 0.0% | +126.3% | 0.154% | |
| 5/12/2025 | Swiss National Bank | 116,700 | $1.39M | 0.0% | +9.2% | 0.153% | |
| 5/9/2025 | Deutsche Bank AG | 380,148 | $4.52M | 0.0% | -28.4% | 0.499% | |
| 5/9/2025 | Charles Schwab Investment Management Inc. | 582,066 | $6.92M | 0.0% | +1.6% | 0.764% | |
| 5/9/2025 | Vanguard Group Inc. | 4,415,122 | $52.45M | 0.0% | +1.6% | 5.791% | |
| 5/9/2025 | IQ EQ FUND MANAGEMENT IRELAND Ltd | 14,249 | $169K | 0.0% | N/A | 0.019% | |
| 5/8/2025 | XTX Topco Ltd | 18,716 | $222K | 0.0% | N/A | 0.025% | |
| 5/7/2025 | Zurcher Kantonalbank Zurich Cantonalbank | 18,829 | $224K | 0.0% | +13.6% | 0.025% | |
| 5/7/2025 | ARK Investment Management LLC | 1,590,910 | $18.90M | 0.2% | +4.0% | 2.087% | |
| 5/7/2025 | TD Asset Management Inc | 42,420 | $504K | 0.0% | +8.1% | 0.056% | |
| 5/7/2025 | Nikko Asset Management Americas Inc. | 755,970 | $8.98M | 0.1% | -4.2% | 0.992% | |
| 5/6/2025 | Universal Beteiligungs und Servicegesellschaft mbH | 18,830 | $224K | 0.0% | N/A | 0.025% | |
| 5/6/2025 | Y Intercept Hong Kong Ltd | 31,458 | $374K | 0.0% | N/A | 0.041% | |
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| 5/5/2025 | Hussman Strategic Advisors Inc. | 42,000 | $499K | 0.1% | N/A | 0.055% | |
| 5/2/2025 | Victory Capital Management Inc. | 29,660 | $352K | 0.0% | -50.7% | 0.039% | |
| 5/2/2025 | Massachusetts Financial Services Co. MA | 43,006 | $511K | 0.0% | -36.2% | 0.056% | |
| 5/1/2025 | New York State Common Retirement Fund | 52,688 | $626K | 0.0% | +148.6% | 0.069% | |
| 5/1/2025 | Arizona State Retirement System | 17,253 | $205K | 0.0% | +8.7% | 0.023% | |
| 4/29/2025 | Bank of New York Mellon Corp | 205,078 | $2.44M | 0.0% | +7.4% | 0.269% | |
| 4/25/2025 | Sumitomo Mitsui Trust Group Inc. | 755,970 | $8.98M | 0.0% | -4.2% | 0.992% | |
| 4/17/2025 | Exchange Traded Concepts LLC | 9,145 | $109K | 0.0% | +38.9% | 0.012% | |
| 4/8/2025 | Rhumbline Advisers | 110,488 | $1.31M | 0.0% | +7.0% | 0.145% | |
| 4/7/2025 | GAMMA Investing LLC | 14,018 | $167K | 0.0% | +202.2% | 0.018% | |
| 3/24/2025 | Wellington Management Group LLP | 3,586,605 | $67.57M | 0.0% | +3.0% | 4.726% | |
| 2/19/2025 | GF Fund Management CO. LTD. | 1,487 | $28K | 0.0% | N/A | 0.002% | |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 146,713 | $2.76M | 0.0% | +14.2% | 0.193% | |
| 2/17/2025 | Woodline Partners LP | 338,462 | $6.38M | 0.0% | +0.5% | 0.446% | |
| 2/17/2025 | Velan Capital Investment Management LP | 97,889 | $1.84M | 1.6% | N/A | 0.129% | |
| 2/17/2025 | Vestal Point Capital LP | 485,000 | $9.14M | 0.5% | +14.1% | 0.639% | |
| 2/17/2025 | Soleus Capital Management L.P. | 2,102,833 | $39.62M | 2.5% | +97.3% | 2.771% | |
| 2/17/2025 | Squarepoint Ops LLC | 76,634 | $1.44M | 0.0% | +13.9% | 0.101% | |
| 2/17/2025 | Twinbeech Capital LP | 29,776 | $561K | 0.0% | -54.5% | 0.039% | |
| 2/17/2025 | Two Sigma Advisers LP | 79,100 | $1.49M | 0.0% | +33.8% | 0.104% | |
| 2/17/2025 | Two Sigma Investments LP | 135,084 | $2.55M | 0.0% | +166.4% | 0.178% | |
| 2/17/2025 | Tema Etfs LLC | 22,557 | $425K | 0.2% | N/A | 0.030% | |
| 2/17/2025 | Rafferty Asset Management LLC | 116,186 | $2.19M | 0.0% | +24.1% | 0.153% | |
| 2/17/2025 | Redmile Group LLC | 4,192,627 | $78.99M | 5.5% | -2.1% | 5.525% | |
| 2/17/2025 | Point72 Asset Management L.P. | 872,959 | $16.45M | 0.0% | N/A | 1.150% | |
| 2/17/2025 | ProShare Advisors LLC | 23,132 | $436K | 0.0% | +45.8% | 0.030% | |
| 2/17/2025 | Parkman Healthcare Partners LLC | 532,172 | $10.03M | 1.3% | +21.2% | 0.701% | |
| 2/17/2025 | Patient Square Capital LP | 446,296 | $8.41M | 3.1% | +37.0% | 0.588% | |
| 2/17/2025 | Nomura Holdings Inc. | 10,514 | $198K | 0.0% | N/A | 0.014% | |
| 2/17/2025 | Nuveen Asset Management LLC | 409,637 | $7.72M | 0.0% | -39.2% | 0.540% | |
| 2/17/2025 | Millennium Management LLC | 424,137 | $7.99M | 0.0% | +91.3% | 0.559% | |
| 2/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 44,518 | $838K | 0.0% | +15.3% | 0.059% | |
| 2/17/2025 | Integral Health Asset Management LLC | 250,000 | $4.71M | 0.4% | +25.0% | 0.329% | |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 229,369 | $4.32M | 0.0% | N/A | 0.302% | |
| 2/17/2025 | Ensign Peak Advisors Inc | 374,673 | $7.06M | 0.0% | +108.2% | 0.494% | |
| 2/17/2025 | Fred Alger Management LLC | 168,762 | $3.18M | 0.0% | +1.7% | 0.222% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 112,841 | $2.13M | 0.0% | +54.9% | 0.149% | |
| 2/17/2025 | Deutsche Bank AG | 531,197 | $10.01M | 0.0% | -37.8% | 0.700% | |
| 2/17/2025 | Driehaus Capital Management LLC | 1,279,691 | $24.11M | 0.2% | -0.5% | 1.686% | |
| 2/17/2025 | Deep Track Capital LP | 3,000,000 | $56.52M | 2.1% | -22.4% | 3.953% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 124,025 | $2.34M | 0.0% | N/A | 0.163% | |
| 2/17/2025 | Brevan Howard Capital Management LP | 21,495 | $405K | 0.0% | N/A | 0.028% | |
| 2/17/2025 | Bank of America Corp DE | 150,935 | $2.84M | 0.0% | +9.3% | 0.199% | |
| 2/17/2025 | BNP Paribas Financial Markets | 8,700 | $164K | 0.0% | N/A | 0.011% | |
| 2/17/2025 | Ameriprise Financial Inc. | 32,152 | $606K | 0.0% | +111.1% | 0.042% | |
| 2/14/2025 | Boxer Capital Management LLC | 563,067 | $10.61M | 0.9% | N/A | 0.742% | |
| 2/14/2025 | RA Capital Management L.P. | 1,333,333 | $25.12M | 0.3% | N/A | 1.757% | |
| 2/14/2025 | Freestone Grove Partners LP | 16,724 | $315K | 0.0% | N/A | 0.022% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 402,955 | $7.59M | 0.0% | +13.3% | 0.531% | |
| 2/14/2025 | Darwin Global Management Ltd. | 163,681 | $3.08M | 0.3% | N/A | 0.216% | |
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| 2/14/2025 | Northern Trust Corp | 659,788 | $12.43M | 0.0% | +16.4% | 0.869% | |
| 2/14/2025 | The Manufacturers Life Insurance Company | 31,025 | $585K | 0.0% | +2.1% | 0.041% | |
| 2/14/2025 | Aquatic Capital Management LLC | 4,610 | $87K | 0.0% | N/A | 0.006% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 3,458 | $65K | 0.0% | -37.3% | 0.005% | |
| 2/14/2025 | Lord Abbett & CO. LLC | 437,772 | $8.25M | 0.0% | +24.8% | 0.577% | |
| 2/14/2025 | Voya Investment Management LLC | 55,079 | $1.04M | 0.0% | +171.8% | 0.073% | |
| 2/14/2025 | T. Rowe Price Investment Management Inc. | 2,380,428 | $44.85M | 0.0% | -6.6% | 3.137% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 3,007,327 | $56.66M | 0.0% | -2.0% | 3.963% | |
| 2/14/2025 | Hsbc Holdings PLC | 12,107 | $226K | 0.0% | N/A | 0.016% | |
| 2/14/2025 | Tower Research Capital LLC TRC | 14,885 | $280K | 0.0% | +422.5% | 0.020% | |
