Alpha Teknova (TKNO) Competitors $5.68 -0.08 (-1.39%) Closing price 10/24/2025 04:00 PM EasternExtended Trading$5.62 -0.05 (-0.97%) As of 10/24/2025 06:51 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock TKNO vs. UPB, SEPN, SANA, COLL, PHAR, BCAX, RAPP, CRON, PGEN, and XNCRShould you be buying Alpha Teknova stock or one of its competitors? The main competitors of Alpha Teknova include Upstream Bio (UPB), Septerna (SEPN), Sana Biotechnology (SANA), Collegium Pharmaceutical (COLL), Pharming Group (PHAR), Bicara Therapeutics (BCAX), Rapport Therapeutics (RAPP), Cronos Group (CRON), Precigen (PGEN), and Xencor (XNCR). These companies are all part of the "pharmaceutical products" industry. Alpha Teknova vs. Its Competitors Upstream Bio Septerna Sana Biotechnology Collegium Pharmaceutical Pharming Group Bicara Therapeutics Rapport Therapeutics Cronos Group Precigen Xencor Upstream Bio (NASDAQ:UPB) and Alpha Teknova (NASDAQ:TKNO) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, institutional ownership, valuation, profitability, analyst recommendations, risk, dividends and earnings. Which has stronger valuation and earnings, UPB or TKNO? Alpha Teknova has higher revenue and earnings than Upstream Bio. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioUpstream Bio$2.37M497.25-$62.81MN/AN/AAlpha Teknova$37.74M8.05-$26.75M-$0.42-13.52 Does the media favor UPB or TKNO? In the previous week, Alpha Teknova had 2 more articles in the media than Upstream Bio. MarketBeat recorded 6 mentions for Alpha Teknova and 4 mentions for Upstream Bio. Upstream Bio's average media sentiment score of 0.62 beat Alpha Teknova's score of 0.41 indicating that Upstream Bio is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Upstream Bio 0 Very Positive mention(s) 1 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Alpha Teknova 0 Very Positive mention(s) 1 Positive mention(s) 3 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Do analysts prefer UPB or TKNO? Upstream Bio currently has a consensus price target of $53.33, indicating a potential upside of 143.98%. Alpha Teknova has a consensus price target of $10.00, indicating a potential upside of 76.06%. Given Upstream Bio's higher probable upside, equities analysts plainly believe Upstream Bio is more favorable than Alpha Teknova.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Upstream Bio 1 Sell rating(s) 0 Hold rating(s) 5 Buy rating(s) 0 Strong Buy rating(s) 2.67Alpha Teknova 1 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 1 Strong Buy rating(s) 2.67 Do institutionals and insiders have more ownership in UPB or TKNO? 13.8% of Alpha Teknova shares are owned by institutional investors. 13.6% of Upstream Bio shares are owned by company insiders. Comparatively, 12.5% of Alpha Teknova shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth. Is UPB or TKNO more profitable? Alpha Teknova has a net margin of -55.24% compared to Upstream Bio's net margin of -3,836.58%. Alpha Teknova's return on equity of -26.51% beat Upstream Bio's return on equity.Company Net Margins Return on Equity Return on Assets Upstream Bio-3,836.58% -35.90% -26.26% Alpha Teknova -55.24%-26.51%-18.40% SummaryAlpha Teknova beats Upstream Bio on 8 of the 13 factors compared between the two stocks. Get Alpha Teknova News Delivered to You Automatically Sign up to receive the latest news and ratings for TKNO and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding TKNO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart TKNO vs. The Competition Export to ExcelMetricAlpha TeknovaMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$303.97M$3.46B$6.21B$10.81BDividend YieldN/A2.28%5.72%4.80%P/E Ratio-13.5228.5131.6030.99Price / Sales8.05497.40595.06133.64Price / CashN/A46.9537.2561.86Price / Book3.6610.4012.056.61Net Income-$26.75M-$52.83M$3.34B$277.10M7 Day Performance10.72%2.10%1.94%2.57%1 Month Performance-6.43%10.17%6.88%3.20%1 Year Performance-16.35%16.57%56.06%33.22% Alpha Teknova Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)TKNOAlpha Teknova1.8535 of 5 stars$5.68-1.4%$10.00+76.1%-16.3%$303.97M$37.74M-13.52240News CoverageAnalyst ForecastUPBUpstream Bio1.9073 of 5 stars$20.08+2.3%$56.50+181.4%-12.8%$1.06B$2.37M0.0038Analyst ForecastSEPNSepterna1.7356 of 5 stars$24.09+4.4%$26.75+11.0%N/A$1.03B$1.08M-2.39N/AAnalyst ForecastSANASana Biotechnology2.6552 of 5 stars$4.34+0.5%$7.50+72.8%+48.7%$1.03BN/A-4.09380Analyst ForecastGap UpCOLLCollegium Pharmaceutical3.6736 of 5 stars$32.04flat$42.33+32.1%+1.7%$1.01B$631.45M30.81210News CoverageAnalyst DowngradePHARPharming Group2.6405 of 5 stars$14.61+2.4%$30.00+105.3%+56.3%$977.71M$297.20M-112.38280News CoverageAnalyst UpgradeGap DownBCAXBicara Therapeutics2.6762 of 5 stars$18.51+4.1%$31.86+72.1%-23.8%$971.01MN/A-5.8432Gap DownRAPPRapport Therapeutics3.1462 of 5 stars$26.19-1.2%$35.33+34.9%+7.1%$967.20MN/A-10.48N/APositive NewsAnalyst ForecastGap UpCRONCronos Group0.9379 of 5 stars$2.55+1.6%N/A+13.5%$961.06M$117.61M51.00450News CoveragePositive NewsAnalyst ForecastPGENPrecigen4.3917 of 5 stars$3.21+2.9%$8.25+157.0%+409.4%$929.68M$3.92M-7.64190Analyst ForecastXNCRXencor3.8029 of 5 stars$13.96+7.1%$24.22+73.5%-37.6%$929.34M$110.49M-5.82280News Coverage Related Companies and Tools Related Companies UPB Competitors SEPN Competitors SANA Competitors COLL Competitors PHAR Competitors BCAX Competitors RAPP Competitors CRON Competitors PGEN Competitors XNCR Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:TKNO) was last updated on 10/26/2025 by MarketBeat.com Staff From Our PartnersU.S. Government Sparking Crypto RallyMissed Bitcoin when it was $100? 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