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Xencor (XNCR) Competitors

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$24.41 +0.15 (+0.62%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$24.68 +0.27 (+1.11%)
As of 09/11/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

XNCR vs. RYTM, SRRK, CGON, MIRM, and ORKA

Should you buy Xencor stock or one of its competitors? Xencor's main competitors and comparable companies include Rhythm Pharmaceuticals (RYTM), Scholar Rock (SRRK), CG Oncology (CGON), Mirum Pharmaceuticals (MIRM), and Oruka Therapeutics (ORKA). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Xencor compare to Rhythm Pharmaceuticals?

Xencor (NASDAQ:XNCR) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their risk, media sentiment, valuation, institutional ownership, earnings, dividends, profitability and analyst recommendations.

In the previous week, Rhythm Pharmaceuticals had 2 more articles in the media than Xencor. MarketBeat recorded 6 mentions for Rhythm Pharmaceuticals and 4 mentions for Xencor. Xencor's average media sentiment score of 1.39 beat Rhythm Pharmaceuticals' score of 0.63 indicating that Xencor is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xencor
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Rhythm Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Xencor has a beta of 0.88, suggesting that its stock price is 12% less volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.97, suggesting that its stock price is 97% more volatile than the broader market.

Xencor presently has a consensus target price of $31.86, suggesting a potential upside of 30.51%. Rhythm Pharmaceuticals has a consensus target price of $141.12, suggesting a potential upside of 34.77%. Given Rhythm Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Rhythm Pharmaceuticals is more favorable than Xencor.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xencor
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.67
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.74

Xencor has higher earnings, but lower revenue than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Xencor, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xencor$125.58M14.45-$91.92M-$2.17N/A
Rhythm Pharmaceuticals$189.76M37.82-$196.54M-$3.11N/A

Rhythm Pharmaceuticals has a net margin of -85.59% compared to Xencor's net margin of -155.59%. Xencor's return on equity of -28.66% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Xencor-155.59% -28.66% -20.38%
Rhythm Pharmaceuticals -85.59%-159.87%-44.00%

Summary

Rhythm Pharmaceuticals beats Xencor on 8 of the 15 factors compared between the two stocks.

How does Xencor compare to Scholar Rock?

Scholar Rock (NASDAQ:SRRK) and Xencor (NASDAQ:XNCR) are both healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their risk, dividends, institutional ownership, earnings, valuation, media sentiment, profitability and analyst recommendations.

Scholar Rock has a net margin of 0.00% compared to Xencor's net margin of -155.59%. Xencor's return on equity of -28.66% beat Scholar Rock's return on equity.

Company Net Margins Return on Equity Return on Assets
Scholar RockN/A -160.19% -87.18%
Xencor -155.59%-28.66%-20.38%

Scholar Rock presently has a consensus price target of $58.77, suggesting a potential upside of 6.06%. Xencor has a consensus price target of $31.86, suggesting a potential upside of 30.51%. Given Xencor's higher possible upside, analysts plainly believe Xencor is more favorable than Scholar Rock.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Scholar Rock
1 Sell rating(s)
1 Hold rating(s)
10 Buy rating(s)
4 Strong Buy rating(s)
3.06
Xencor
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.67

In the previous week, Scholar Rock had 8 more articles in the media than Xencor. MarketBeat recorded 12 mentions for Scholar Rock and 4 mentions for Xencor. Xencor's average media sentiment score of 1.39 beat Scholar Rock's score of 0.71 indicating that Xencor is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Scholar Rock
3 Very Positive mention(s)
2 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Xencor
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Scholar Rock has a beta of 0.67, suggesting that its stock price is 33% less volatile than the broader market. Comparatively, Xencor has a beta of 0.88, suggesting that its stock price is 12% less volatile than the broader market.

91.1% of Scholar Rock shares are held by institutional investors. 10.3% of Scholar Rock shares are held by company insiders. Comparatively, 5.1% of Xencor shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Xencor has higher revenue and earnings than Scholar Rock. Scholar Rock is trading at a lower price-to-earnings ratio than Xencor, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Scholar RockN/AN/A-$377.94M-$3.45N/A
Xencor$125.58M14.45-$91.92M-$2.17N/A

Summary

Xencor beats Scholar Rock on 9 of the 16 factors compared between the two stocks.

How does Xencor compare to CG Oncology?

Xencor (NASDAQ:XNCR) and CG Oncology (NASDAQ:CGON) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their analyst recommendations, risk, institutional ownership, valuation, dividends, earnings, profitability and media sentiment.

Xencor presently has a consensus target price of $31.86, indicating a potential upside of 30.51%. CG Oncology has a consensus target price of $87.78, indicating a potential upside of 21.32%. Given Xencor's higher possible upside, equities analysts clearly believe Xencor is more favorable than CG Oncology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xencor
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.67
CG Oncology
1 Sell rating(s)
1 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.73

Xencor has a net margin of -155.59% compared to CG Oncology's net margin of -3,602.68%. CG Oncology's return on equity of -25.20% beat Xencor's return on equity.

Company Net Margins Return on Equity Return on Assets
Xencor-155.59% -28.66% -20.38%
CG Oncology -3,602.68%-25.20%-23.98%

In the previous week, CG Oncology had 2 more articles in the media than Xencor. MarketBeat recorded 6 mentions for CG Oncology and 4 mentions for Xencor. Xencor's average media sentiment score of 1.39 beat CG Oncology's score of 1.35 indicating that Xencor is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xencor
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
CG Oncology
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Xencor has higher revenue and earnings than CG Oncology. CG Oncology is trading at a lower price-to-earnings ratio than Xencor, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xencor$125.58M14.45-$91.92M-$2.17N/A
CG Oncology$4.04M1,587.40-$160.99M-$2.69N/A

26.6% of CG Oncology shares are held by institutional investors. 5.1% of Xencor shares are held by insiders. Comparatively, 4.8% of CG Oncology shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Xencor has a beta of 0.88, indicating that its share price is 12% less volatile than the broader market. Comparatively, CG Oncology has a beta of 0.24, indicating that its share price is 76% less volatile than the broader market.

Summary

Xencor beats CG Oncology on 11 of the 17 factors compared between the two stocks.

How does Xencor compare to Mirum Pharmaceuticals?

Xencor (NASDAQ:XNCR) and Mirum Pharmaceuticals (NASDAQ:MIRM) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, media sentiment, profitability, earnings, institutional ownership, valuation, dividends and risk.

Mirum Pharmaceuticals has higher revenue and earnings than Xencor. Xencor is trading at a lower price-to-earnings ratio than Mirum Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xencor$125.58M14.45-$91.92M-$2.17N/A
Mirum Pharmaceuticals$521.31M12.23-$23.36M-$14.55N/A

Mirum Pharmaceuticals has a net margin of -139.18% compared to Xencor's net margin of -155.59%. Xencor's return on equity of -28.66% beat Mirum Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Xencor-155.59% -28.66% -20.38%
Mirum Pharmaceuticals -139.18%-36.28%-8.54%

In the previous week, Mirum Pharmaceuticals had 2 more articles in the media than Xencor. MarketBeat recorded 6 mentions for Mirum Pharmaceuticals and 4 mentions for Xencor. Xencor's average media sentiment score of 1.39 beat Mirum Pharmaceuticals' score of 0.42 indicating that Xencor is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xencor
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Mirum Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral

Xencor currently has a consensus price target of $31.86, indicating a potential upside of 30.51%. Mirum Pharmaceuticals has a consensus price target of $137.31, indicating a potential upside of 39.80%. Given Mirum Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Mirum Pharmaceuticals is more favorable than Xencor.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xencor
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.67
Mirum Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.93

Xencor has a beta of 0.88, suggesting that its share price is 12% less volatile than the broader market. Comparatively, Mirum Pharmaceuticals has a beta of 0.49, suggesting that its share price is 51% less volatile than the broader market.

Summary

Mirum Pharmaceuticals beats Xencor on 9 of the 14 factors compared between the two stocks.

How does Xencor compare to Oruka Therapeutics?

Xencor (NASDAQ:XNCR) and Oruka Therapeutics (NASDAQ:ORKA) are both healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, profitability, earnings, institutional ownership, media sentiment, valuation and risk.

Xencor has a beta of 0.88, suggesting that its share price is 12% less volatile than the broader market. Comparatively, Oruka Therapeutics has a beta of -0.34, suggesting that its share price is 134% less volatile than the broader market.

In the previous week, Oruka Therapeutics had 3 more articles in the media than Xencor. MarketBeat recorded 7 mentions for Oruka Therapeutics and 4 mentions for Xencor. Xencor's average media sentiment score of 1.39 beat Oruka Therapeutics' score of -0.07 indicating that Xencor is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xencor
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Oruka Therapeutics
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Oruka Therapeutics has a net margin of 0.00% compared to Xencor's net margin of -155.59%. Oruka Therapeutics' return on equity of -21.65% beat Xencor's return on equity.

Company Net Margins Return on Equity Return on Assets
Xencor-155.59% -28.66% -20.38%
Oruka Therapeutics N/A -21.65%-20.88%

Xencor presently has a consensus target price of $31.86, indicating a potential upside of 30.51%. Oruka Therapeutics has a consensus target price of $133.00, indicating a potential upside of 43.97%. Given Oruka Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Oruka Therapeutics is more favorable than Xencor.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xencor
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.67
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

56.4% of Oruka Therapeutics shares are held by institutional investors. 5.1% of Xencor shares are held by insiders. Comparatively, 23.5% of Oruka Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Xencor has higher revenue and earnings than Oruka Therapeutics. Oruka Therapeutics is trading at a lower price-to-earnings ratio than Xencor, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xencor$125.58M14.45-$91.92M-$2.17N/A
Oruka TherapeuticsN/AN/A-$105.43M-$2.03N/A

Summary

Oruka Therapeutics beats Xencor on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding XNCR and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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XNCR vs. The Competition

MetricXencorBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.81B$3.86B$7.17B$12.85B
Dividend YieldN/A3.66%2.57%11.71%
P/E Ratio-11.2514.18274.9425.33
Price / Sales14.451,375.01685.45111.12
Price / CashN/A106.5076.6551.52
Price / Book2.7415.1210.336.20
Net Income-$91.92M-$22.86M$3.50B$358.50M
7 Day Performance-8.27%-4.34%-3.32%-2.35%
1 Month Performance5.31%-0.02%-0.41%-2.77%
1 Year Performance183.84%40.64%19.21%7.63%

Xencor Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
XNCR
Xencor
2.5603 of 5 stars
$24.41
+0.6%
$31.86
+30.5%
+183.8%$1.81B$125.58MN/A260
RYTM
Rhythm Pharmaceuticals
2.5613 of 5 stars
$102.27
-0.5%
$141.12
+38.0%
+8.8%$7.01B$189.76MN/A140
SRRK
Scholar Rock
1.812 of 5 stars
$57.13
+3.3%
$58.77
+2.9%
+75.0%$6.96BN/AN/A140
CGON
CG Oncology
3.1647 of 5 stars
$74.25
-0.6%
$87.78
+18.2%
+117.0%$6.58B$4.04MN/A61
MIRM
Mirum Pharmaceuticals
2.7522 of 5 stars
$100.87
0.0%
$137.31
+36.1%
+32.2%$6.53B$521.31MN/A140

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This page (NASDAQ:XNCR) was last updated on 9/13/2026 by MarketBeat.com Staff.
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