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Tempest Therapeutics (TPST) Competitors

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$1.07 +0.09 (+9.13%)
Closing price 07/15/2026 04:00 PM Eastern
Extended Trading
$1.04 -0.03 (-2.80%)
As of 07/15/2026 07:51 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

TPST vs. TCRX, ANVS, EDSA, SCLX, and PMVP

Should you buy Tempest Therapeutics stock or one of its competitors? MarketBeat compares Tempest Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Tempest Therapeutics include TScan Therapeutics (TCRX), Annovis Bio (ANVS), Edesa Biotech (EDSA), Scilex (SCLX), and PMV Pharmaceuticals (PMVP). These companies are all part of the "pharmaceutical products" industry.

How does Tempest Therapeutics compare to TScan Therapeutics?

TScan Therapeutics (NASDAQ:TCRX) and Tempest Therapeutics (NASDAQ:TPST) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, dividends, profitability, analyst recommendations, valuation, risk, institutional ownership and media sentiment.

TScan Therapeutics has a beta of 1.04, suggesting that its share price is 4% more volatile than the broader market. Comparatively, Tempest Therapeutics has a beta of -1.73, suggesting that its share price is 273% less volatile than the broader market.

Tempest Therapeutics has a net margin of 0.00% compared to TScan Therapeutics' net margin of -1,360.61%. TScan Therapeutics' return on equity of -91.94% beat Tempest Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
TScan Therapeutics-1,360.61% -91.94% -50.15%
Tempest Therapeutics N/A -355.61%-121.21%

Tempest Therapeutics has lower revenue, but higher earnings than TScan Therapeutics. TScan Therapeutics is trading at a lower price-to-earnings ratio than Tempest Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
TScan Therapeutics$10.32M5.83-$129.77M-$0.96N/A
Tempest TherapeuticsN/AN/A-$26.26M-$6.01N/A

TScan Therapeutics currently has a consensus price target of $6.00, indicating a potential upside of 552.17%. Given TScan Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe TScan Therapeutics is more favorable than Tempest Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
TScan Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Tempest Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50

82.8% of TScan Therapeutics shares are owned by institutional investors. Comparatively, 22.5% of Tempest Therapeutics shares are owned by institutional investors. 6.3% of TScan Therapeutics shares are owned by company insiders. Comparatively, 36.3% of Tempest Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

In the previous week, Tempest Therapeutics had 2 more articles in the media than TScan Therapeutics. MarketBeat recorded 3 mentions for Tempest Therapeutics and 1 mentions for TScan Therapeutics. TScan Therapeutics' average media sentiment score of 1.89 beat Tempest Therapeutics' score of 1.29 indicating that TScan Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
TScan Therapeutics Very Positive
Tempest Therapeutics Positive

Summary

TScan Therapeutics beats Tempest Therapeutics on 10 of the 15 factors compared between the two stocks.

How does Tempest Therapeutics compare to Annovis Bio?

Annovis Bio (NYSE:ANVS) and Tempest Therapeutics (NASDAQ:TPST) are both small-cap medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their valuation, risk, profitability, institutional ownership, media sentiment, dividends, earnings and analyst recommendations.

In the previous week, Annovis Bio had 2 more articles in the media than Tempest Therapeutics. MarketBeat recorded 5 mentions for Annovis Bio and 3 mentions for Tempest Therapeutics. Tempest Therapeutics' average media sentiment score of 1.29 beat Annovis Bio's score of 1.04 indicating that Tempest Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Annovis Bio
0 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Tempest Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Annovis Bio is trading at a lower price-to-earnings ratio than Tempest Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Annovis BioN/AN/A-$28.85M-$1.71N/A
Tempest TherapeuticsN/AN/A-$26.26M-$6.01N/A

15.8% of Annovis Bio shares are owned by institutional investors. Comparatively, 22.5% of Tempest Therapeutics shares are owned by institutional investors. 20.8% of Annovis Bio shares are owned by insiders. Comparatively, 36.3% of Tempest Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Annovis Bio's return on equity of -318.08% beat Tempest Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Annovis BioN/A -318.08% -215.47%
Tempest Therapeutics N/A -355.61%-121.21%

Annovis Bio has a beta of 1.19, meaning that its share price is 19% more volatile than the broader market. Comparatively, Tempest Therapeutics has a beta of -1.73, meaning that its share price is 273% less volatile than the broader market.

Annovis Bio presently has a consensus price target of $11.67, suggesting a potential upside of 546.35%. Given Annovis Bio's stronger consensus rating and higher possible upside, equities analysts plainly believe Annovis Bio is more favorable than Tempest Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Annovis Bio
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.60
Tempest Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50

Summary

Annovis Bio beats Tempest Therapeutics on 8 of the 14 factors compared between the two stocks.

How does Tempest Therapeutics compare to Edesa Biotech?

Edesa Biotech (NASDAQ:EDSA) and Tempest Therapeutics (NASDAQ:TPST) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their earnings, analyst recommendations, media sentiment, dividends, risk, valuation, profitability and institutional ownership.

Edesa Biotech currently has a consensus price target of $5.00, indicating a potential downside of 27.22%. Given Edesa Biotech's stronger consensus rating and higher probable upside, research analysts clearly believe Edesa Biotech is more favorable than Tempest Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Edesa Biotech
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.67
Tempest Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50

Edesa Biotech is trading at a lower price-to-earnings ratio than Tempest Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Edesa BiotechN/AN/A-$7.19M-$1.34N/A
Tempest TherapeuticsN/AN/A-$26.26M-$6.01N/A

Edesa Biotech has a beta of 1.03, suggesting that its stock price is 3% more volatile than the broader market. Comparatively, Tempest Therapeutics has a beta of -1.73, suggesting that its stock price is 273% less volatile than the broader market.

Edesa Biotech's return on equity of -286.52% beat Tempest Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Edesa BiotechN/A -286.52% -75.36%
Tempest Therapeutics N/A -355.61%-121.21%

5.5% of Edesa Biotech shares are held by institutional investors. Comparatively, 22.5% of Tempest Therapeutics shares are held by institutional investors. 24.4% of Edesa Biotech shares are held by company insiders. Comparatively, 36.3% of Tempest Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

In the previous week, Tempest Therapeutics had 2 more articles in the media than Edesa Biotech. MarketBeat recorded 3 mentions for Tempest Therapeutics and 1 mentions for Edesa Biotech. Edesa Biotech's average media sentiment score of 1.89 beat Tempest Therapeutics' score of 1.29 indicating that Edesa Biotech is being referred to more favorably in the media.

Company Overall Sentiment
Edesa Biotech Very Positive
Tempest Therapeutics Positive

Summary

Edesa Biotech beats Tempest Therapeutics on 10 of the 14 factors compared between the two stocks.

How does Tempest Therapeutics compare to Scilex?

Tempest Therapeutics (NASDAQ:TPST) and Scilex (NASDAQ:SCLX) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their profitability, risk, analyst recommendations, dividends, media sentiment, earnings, institutional ownership and valuation.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tempest Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50
Scilex
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Tempest Therapeutics has a beta of -1.73, suggesting that its share price is 273% less volatile than the broader market. Comparatively, Scilex has a beta of 1.66, suggesting that its share price is 66% more volatile than the broader market.

Tempest Therapeutics has a net margin of 0.00% compared to Scilex's net margin of -1,110.17%. Scilex's return on equity of 0.00% beat Tempest Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Tempest TherapeuticsN/A -355.61% -121.21%
Scilex -1,110.17%N/A -143.55%

In the previous week, Tempest Therapeutics and Tempest Therapeutics both had 3 articles in the media. Tempest Therapeutics' average media sentiment score of 1.29 beat Scilex's score of 0.83 indicating that Tempest Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Tempest Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Scilex
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Tempest Therapeutics has higher earnings, but lower revenue than Scilex. Scilex is trading at a lower price-to-earnings ratio than Tempest Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Tempest TherapeuticsN/AN/A-$26.26M-$6.01N/A
Scilex$30.25M2.59-$358.73M-$40.47N/A

22.5% of Tempest Therapeutics shares are owned by institutional investors. Comparatively, 69.7% of Scilex shares are owned by institutional investors. 36.3% of Tempest Therapeutics shares are owned by company insiders. Comparatively, 4.5% of Scilex shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Summary

Tempest Therapeutics beats Scilex on 8 of the 12 factors compared between the two stocks.

How does Tempest Therapeutics compare to PMV Pharmaceuticals?

Tempest Therapeutics (NASDAQ:TPST) and PMV Pharmaceuticals (NASDAQ:PMVP) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, media sentiment, earnings, risk, profitability, dividends, valuation and analyst recommendations.

PMV Pharmaceuticals is trading at a lower price-to-earnings ratio than Tempest Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Tempest TherapeuticsN/AN/A-$26.26M-$6.01N/A
PMV PharmaceuticalsN/AN/A-$77.74M-$1.49N/A

Tempest Therapeutics has a beta of -1.73, indicating that its share price is 273% less volatile than the broader market. Comparatively, PMV Pharmaceuticals has a beta of 1.33, indicating that its share price is 33% more volatile than the broader market.

PMV Pharmaceuticals has a consensus price target of $4.00, indicating a potential upside of 185.71%. Given PMV Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe PMV Pharmaceuticals is more favorable than Tempest Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tempest Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50
PMV Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75

22.5% of Tempest Therapeutics shares are owned by institutional investors. Comparatively, 90.2% of PMV Pharmaceuticals shares are owned by institutional investors. 36.3% of Tempest Therapeutics shares are owned by company insiders. Comparatively, 10.2% of PMV Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

PMV Pharmaceuticals' return on equity of -68.98% beat Tempest Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Tempest TherapeuticsN/A -355.61% -121.21%
PMV Pharmaceuticals N/A -68.98%-62.70%

In the previous week, Tempest Therapeutics had 2 more articles in the media than PMV Pharmaceuticals. MarketBeat recorded 3 mentions for Tempest Therapeutics and 1 mentions for PMV Pharmaceuticals. Tempest Therapeutics' average media sentiment score of 1.29 beat PMV Pharmaceuticals' score of 0.72 indicating that Tempest Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Tempest Therapeutics Positive
PMV Pharmaceuticals Positive

Summary

PMV Pharmaceuticals beats Tempest Therapeutics on 9 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding TPST and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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TPST vs. The Competition

MetricTempest TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$15.67M$3.01B$6.78B$12.56B
Dividend YieldN/A2.08%2.68%9.45%
P/E Ratio-0.1819.4127.0824.35
Price / SalesN/A354.71487.2376.01
Price / CashN/A56.6848.6360.00
Price / Book0.794.2610.826.31
Net Income-$26.26M$65.13M$3.59B$331.55M
7 Day Performance9.77%-2.62%-1.80%-0.71%
1 Month Performance-14.40%3.29%3.71%0.16%
1 Year Performance-83.96%20.83%27.41%19.66%

Tempest Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
TPST
Tempest Therapeutics
1.5185 of 5 stars
$1.07
+9.1%
N/A-84.0%$15.67MN/AN/A20
TCRX
TScan Therapeutics
4.2713 of 5 stars
$1.05
-0.9%
$6.00
+471.4%
-48.0%$69.27M$10.32MN/A100
ANVS
Annovis Bio
3.6567 of 5 stars
$1.98
+2.3%
$13.50
+583.5%
-33.0%$66.87MN/AN/A3
EDSA
Edesa Biotech
1.6052 of 5 stars
$7.21
-3.9%
$5.00
-30.7%
+215.1%$66.69MN/AN/A20
SCLX
Scilex
0.8447 of 5 stars
$8.07
+3.3%
N/A+37.0%$66.32M$30.25MN/A80

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This page (NASDAQ:TPST) was last updated on 7/16/2026 by MarketBeat.com Staff.
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