Xencor (XNCR) Competitors $9.40 -0.13 (-1.31%) As of 09:30 AM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock XNCR vs. LYEL, APLS, OGN, HCM, IBRX, AMRX, XENE, MIRM, ARWR, and AAPGShould you be buying Xencor stock or one of its competitors? The main competitors of Xencor include Lyell Immunopharma (LYEL), Apellis Pharmaceuticals (APLS), Organon & Co. (OGN), HUTCHMED (HCM), ImmunityBio (IBRX), Amneal Pharmaceuticals (AMRX), Xenon Pharmaceuticals (XENE), Mirum Pharmaceuticals (MIRM), Arrowhead Pharmaceuticals (ARWR), and Ascentage Pharma Group International (AAPG). These companies are all part of the "pharmaceutical products" industry. Xencor vs. Its Competitors Lyell Immunopharma Apellis Pharmaceuticals Organon & Co. HUTCHMED ImmunityBio Amneal Pharmaceuticals Xenon Pharmaceuticals Mirum Pharmaceuticals Arrowhead Pharmaceuticals Ascentage Pharma Group International Xencor (NASDAQ:XNCR) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap medical companies, but which is the superior investment? We will compare the two companies based on the strength of their earnings, media sentiment, valuation, dividends, risk, institutional ownership, community ranking, analyst recommendations and profitability. Do institutionals & insiders hold more shares of XNCR or LYEL? 66.1% of Lyell Immunopharma shares are owned by institutional investors. 4.8% of Xencor shares are owned by company insiders. Comparatively, 25.1% of Lyell Immunopharma shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Which has higher earnings and valuation, XNCR or LYEL? Xencor has higher revenue and earnings than Lyell Immunopharma. Xencor is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioXencor$127.23M5.33-$126.09M-$3.06-3.11Lyell Immunopharma$65K2,143.74-$234.63M-$25.00-0.38 Does the MarketBeat Community believe in XNCR or LYEL? Xencor received 495 more outperform votes than Lyell Immunopharma when rated by MarketBeat users. Likewise, 73.13% of users gave Xencor an outperform vote while only 43.75% of users gave Lyell Immunopharma an outperform vote. CompanyUnderperformOutperformXencorOutperform Votes50973.13% Underperform Votes18726.87% Lyell ImmunopharmaOutperform Votes1443.75% Underperform Votes1856.25% Does the media prefer XNCR or LYEL? In the previous week, Lyell Immunopharma had 1 more articles in the media than Xencor. MarketBeat recorded 7 mentions for Lyell Immunopharma and 6 mentions for Xencor. Xencor's average media sentiment score of 1.07 beat Lyell Immunopharma's score of 0.66 indicating that Xencor is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Xencor 3 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Lyell Immunopharma 1 Very Positive mention(s) 0 Positive mention(s) 3 Neutral mention(s) 1 Negative mention(s) 0 Very Negative mention(s) Positive Is XNCR or LYEL more profitable? Xencor has a net margin of -232.77% compared to Lyell Immunopharma's net margin of -323,792.09%. Xencor's return on equity of -30.92% beat Lyell Immunopharma's return on equity.Company Net Margins Return on Equity Return on Assets Xencor-232.77% -30.92% -21.74% Lyell Immunopharma -323,792.09%-34.64%-30.02% Do analysts recommend XNCR or LYEL? Xencor currently has a consensus target price of $29.50, indicating a potential upside of 209.87%. Lyell Immunopharma has a consensus target price of $20.00, indicating a potential upside of 112.54%. Given Xencor's stronger consensus rating and higher probable upside, analysts plainly believe Xencor is more favorable than Lyell Immunopharma.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Xencor 1 Sell rating(s) 0 Hold rating(s) 7 Buy rating(s) 1 Strong Buy rating(s) 2.89Lyell Immunopharma 1 Sell rating(s) 1 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 1.50 Which has more risk & volatility, XNCR or LYEL? Xencor has a beta of 0.87, meaning that its share price is 13% less volatile than the S&P 500. Comparatively, Lyell Immunopharma has a beta of -0.26, meaning that its share price is 126% less volatile than the S&P 500. SummaryXencor beats Lyell Immunopharma on 15 of the 19 factors compared between the two stocks. Get Xencor News Delivered to You Automatically Sign up to receive the latest news and ratings for XNCR and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding XNCR and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart XNCR vs. The Competition Export to ExcelMetricXencorPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$677.55M$6.85B$5.57B$8.62BDividend YieldN/A2.55%5.28%4.18%P/E Ratio-2.988.7827.1420.06Price / Sales5.33255.49419.32157.08Price / CashN/A65.8538.2534.64Price / Book0.876.557.064.70Net Income-$126.09M$143.93M$3.23B$247.88M7 Day Performance4.39%3.84%2.83%2.63%1 Month Performance8.55%11.20%9.02%6.36%1 Year Performance-56.77%4.18%31.36%14.05% Xencor Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)XNCRXencor4.1934 of 5 stars$9.40-1.3%$29.50+214.0%-56.6%$668.65M$127.23M-2.94280Positive NewsLYELLyell Immunopharma3.1651 of 5 stars$8.22-5.9%$1.00-87.8%-81.3%$2.43B$65K-10.40270Short Interest ↓Gap DownHigh Trading VolumeAPLSApellis Pharmaceuticals4.7675 of 5 stars$19.14+13.1%$40.05+109.3%-54.9%$2.41B$775.84M-9.43770Analyst RevisionHigh Trading VolumeOGNOrganon & Co.4.8019 of 5 stars$9.22-0.1%$18.00+95.3%-50.1%$2.40B$6.29B2.7710,000Trending NewsHCMHUTCHMED0.8558 of 5 stars$13.60-2.1%$19.00+39.7%-4.2%$2.37B$630.20M0.001,760Upcoming EarningsIBRXImmunityBio2.3744 of 5 stars$2.67+0.4%$12.25+358.8%-45.6%$2.36B$31.22M-2.90590High Trading VolumeAMRXAmneal Pharmaceuticals3.731 of 5 stars$7.42+1.4%$11.50+55.0%+10.7%$2.33B$2.83B-10.917,600XENEXenon Pharmaceuticals3.6802 of 5 stars$30.07+4.2%$54.82+82.3%-15.0%$2.31B$7.50M-10.66210Positive NewsOptions VolumeAnalyst RevisionMIRMMirum Pharmaceuticals3.8483 of 5 stars$45.97+3.4%$60.73+32.1%+85.0%$2.28B$379.25M-22.76140Analyst RevisionARWRArrowhead Pharmaceuticals3.6107 of 5 stars$16.40+2.1%$42.13+156.9%-32.1%$2.26B$545.21M-3.17400Analyst RevisionAAPGAscentage Pharma Group InternationalN/A$25.22+3.4%N/AN/A$2.20B$980.65M0.00600 Related Companies and Tools Related Companies Lyell Immunopharma Alternatives Apellis Pharmaceuticals Alternatives Organon & Co. Alternatives HUTCHMED Alternatives ImmunityBio Alternatives Amneal Pharmaceuticals Alternatives Xenon Pharmaceuticals Alternatives Mirum Pharmaceuticals Alternatives Arrowhead Pharmaceuticals Alternatives Ascentage Pharma Group International Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:XNCR) was last updated on 6/12/2025 by MarketBeat.com Staff From Our PartnersTrump’s Exec Order #14154 could be a “Millionaire-Maker”Former Presidential Advisor, Jim Rickards, says Trump could “rewire our economy and hand millions of Americans...Paradigm Press | SponsoredTrump wipes out trillions overnight…Is there anybody more powerful than Donald Trump right now? 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