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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$43.45
+1.9%
$38.67
$23.42
$62.58
$2.48B0.83553,758 shs481,559 shs
Alkermes plc stock logo
ALKS
Alkermes
$31.45
+1.5%
$29.30
$25.17
$36.45
$5.11B0.541.81 million shs1.63 million shs
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$28.31
+4.6%
$25.54
$16.10
$35.72
$3.42B0.692.24 million shs3.02 million shs
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$131.39
-0.2%
$120.01
$75.56
$139.13
$6.57B0.52454,192 shs342,014 shs
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
$29.15
+1.4%
$32.43
$23.82
$44.34
$3.21B1.08569,560 shs442,328 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
+1.88%+7.98%+15.25%+7.13%-4.84%
Alkermes plc stock logo
ALKS
Alkermes
+1.52%-1.53%+13.17%+15.67%+13.50%
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
+4.58%+22.29%+23.03%+42.26%+5.32%
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-0.16%+6.37%+13.32%+23.53%+43.60%
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
+1.43%-0.85%-10.72%-22.00%+4.11%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$43.45
+1.9%
$38.67
$23.42
$62.58
$2.48B0.83553,758 shs481,559 shs
Alkermes plc stock logo
ALKS
Alkermes
$31.45
+1.5%
$29.30
$25.17
$36.45
$5.11B0.541.81 million shs1.63 million shs
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$28.31
+4.6%
$25.54
$16.10
$35.72
$3.42B0.692.24 million shs3.02 million shs
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$131.39
-0.2%
$120.01
$75.56
$139.13
$6.57B0.52454,192 shs342,014 shs
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
$29.15
+1.4%
$32.43
$23.82
$44.34
$3.21B1.08569,560 shs442,328 shs
Analysts Agree—These Gold Picks Outshine the Rest Cover

Unlock the timeless value of gold with our exclusive 2025 Gold Forecasting Report. Explore why gold remains the ultimate investment for safeguarding wealth against inflation, economic shifts, and global uncertainties. Whether you're planning for future generations or seeking a reliable asset in turbulent times, this report is your essential guide to making informed decisions.

Get This Free Report

Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
+1.88%+7.98%+15.25%+7.13%-4.84%
Alkermes plc stock logo
ALKS
Alkermes
+1.52%-1.53%+13.17%+15.67%+13.50%
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
+4.58%+22.29%+23.03%+42.26%+5.32%
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-0.16%+6.37%+13.32%+23.53%+43.60%
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
+1.43%-0.85%-10.72%-22.00%+4.11%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
2.57
Moderate Buy$57.2531.76% Upside
Alkermes plc stock logo
ALKS
Alkermes
2.93
Moderate Buy$42.0033.55% Upside
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
2.47
Hold$33.4718.23% Upside
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
3.00
Buy$178.2035.63% Upside
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
2.63
Moderate Buy$56.3593.31% Upside

Current Analyst Ratings Breakdown

Latest AGIO, AXSM, ZLAB, APLS, and ALKS Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
10/21/2025
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingBuy
10/20/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
Morgan Stanley
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetOverweight$191.00 ➝ $194.00
10/15/2025
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
Wells Fargo & Company
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Initiated CoverageEqual WeightOverweight$29.00 ➝ $32.00
10/14/2025
Alkermes plc stock logo
ALKS
Alkermes
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingHold (C+)
10/8/2025
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingHold (C-)
10/8/2025
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (E+)
10/8/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (D-)
10/8/2025
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (D-)
10/6/2025
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
Zacks Research
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
DowngradeHoldStrong Sell
10/1/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
B. Riley
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Initiated CoverageBuy$179.00
9/30/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
B. Riley
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Initiated CoverageBuy$179.00
(Data available from 10/22/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$36.50M69.16N/AN/A$27.02 per share1.61
Alkermes plc stock logo
ALKS
Alkermes
$1.56B3.33$2.69 per share11.69$9.05 per share3.48
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$781.37M4.58N/AN/A$1.84 per share15.39
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$385.69M17.00N/AN/A$1.18 per share111.35
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
$427.80M7.62N/AN/A$7.68 per share3.80
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$673.72M$11.003.95N/AN/A1,590.42%-3.49%-3.23%10/30/2025 (Estimated)
Alkermes plc stock logo
ALKS
Alkermes
$367.07M$2.0815.1222.961.6723.15%24.86%17.14%10/23/2025 (Estimated)
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
-$197.88M-$1.82N/AN/AN/A-30.24%-116.09%-26.72%10/30/2025 (Estimated)
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-$287.22M-$5.07N/A46.59N/A-49.88%-283.22%-33.06%11/3/2025 (Estimated)
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
-$257.10M-$2.04N/AN/AN/A-49.68%-27.32%-18.85%11/6/2025 (Confirmed)

Latest AGIO, AXSM, ZLAB, APLS, and ALKS Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
11/6/2025Q3 2025
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
-$0.22N/AN/AN/A$150.24 millionN/A
11/3/2025Q3 2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-$0.80N/AN/AN/A$162.96 millionN/A
10/30/2025Q3 2025
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
-$1.94N/AN/AN/A$10.49 millionN/A
10/30/2025Q3 2025
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$0.73N/AN/AN/A$364.58 millionN/A
10/23/2025Q3 2025
Alkermes plc stock logo
ALKS
Alkermes
$0.41N/AN/AN/A$355.23 millionN/A
8/7/2025Q2 2025
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
-$0.37-$0.37N/A-$0.37$125.66 million$109.98 million
8/4/2025Q2 2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-$1.00-$0.92+$0.08-$0.97$140.02 million$150.04 million
7/31/2025Q2 2025
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
-$1.74-$1.93-$0.19-$1.93$9.46 million$12.50 million
7/31/2025Q2 2025
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
-$0.44-$0.33+$0.11-$0.33$187.91 million$171.39 million
7/29/2025Q2 2025
Alkermes plc stock logo
ALKS
Alkermes
$0.42$0.52+$0.10$0.52$343.20 million$390.66 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
N/AN/AN/AN/AN/A
Alkermes plc stock logo
ALKS
Alkermes
N/AN/AN/AN/AN/A
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
N/AN/AN/AN/AN/A
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
N/AN/AN/AN/AN/A
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
N/A
14.48
14.04
Alkermes plc stock logo
ALKS
Alkermes
N/A
3.23
2.85
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
2.90
3.77
3.16
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
1.66
1.57
1.51
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
N/A
3.12
2.93

Institutional Ownership

CompanyInstitutional Ownership
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
N/A
Alkermes plc stock logo
ALKS
Alkermes
95.21%
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
96.29%
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
81.49%
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
41.65%

Insider Ownership

CompanyInsider Ownership
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
4.93%
Alkermes plc stock logo
ALKS
Alkermes
4.40%
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
6.80%
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
22.40%
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
4.96%
CompanyEmployeesShares OutstandingFree FloatOptionable
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
39058.10 million55.24 millionOptionable
Alkermes plc stock logo
ALKS
Alkermes
1,800165.08 million157.82 millionOptionable
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
770126.29 million117.70 millionOptionable
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
38049.90 million38.72 millionOptionable
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
1,869111.76 million106.22 millionOptionable

Recent News About These Companies

Zai Lab Secures RMB300 Million Debt Facility
Zai Lab falls -6.9%
Zai Lab's (ZLAB) Sell (D-) Rating Reiterated at Weiss Ratings
Zai Lab (NASDAQ:ZLAB) Shares Gap Up - Still a Buy?
Zai Lab (ZLAB) Gets a Buy from Cantor Fitzgerald
Zai Lab Limited (ZLAB): A Bull Case Theory
Zai Lab (NASDAQ:ZLAB) Insider Acquires $289,100.00 in Stock
Zai Lab's Double Whammy: Earnings Miss, Phase 3 Setback

New MarketBeat Followers Over Time

Media Sentiment Over Time

Agios Pharmaceuticals stock logo

Agios Pharmaceuticals NASDAQ:AGIO

$43.45 +0.80 (+1.88%)
Closing price 10/21/2025 04:00 PM Eastern
Extended Trading
$43.73 +0.28 (+0.64%)
As of 10/21/2025 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes for the treatment of hemolytic anemias. The company develops AG-946, a PK activator for treating lower-risk myelodysplastic syndrome and hemolytic anemias; and AG-181, a phenylalanine hydroxylase stabilizer for the treatment of phenylketonuria. Its preclinical product is siRNA for the treatment of polycythemia vera, a rare blood disorder. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.

Alkermes stock logo

Alkermes NASDAQ:ALKS

$31.45 +0.47 (+1.52%)
Closing price 10/21/2025 04:00 PM Eastern
Extended Trading
$30.72 -0.72 (-2.31%)
As of 10/21/2025 06:06 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Alkermes plc, a biopharmaceutical company, researches, develops, and commercializes pharmaceutical products to address unmet medical needs of patients in therapeutic areas in the United States, Ireland, and internationally. It has a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia and bipolar I disorder and a pipeline of clinical and preclinical product candidates in development for neurological disorders. Its marketed products include ARISTADA, an intramuscular injectable suspension for the treatment of schizophrenia; ARISTADA INITIO for the treatment of schizophrenia in adults; VIVITROL for the treatment of alcohol and prevention of opioid dependence; and LYBALVI, an oral atypical antipsychotic drug candidate for the treatment of adults with schizophrenia and bipolar I disorder. It has collaboration agreements primarily with Janssen Pharmaceutica N.V., Janssen Pharmaceutica Inc, and Janssen Pharmaceutica International. The company also offers proprietary technology platforms to third parties to enable them to develop, commercialize, and manufacture products. Alkermes plc was founded in 1987 and is headquartered in Dublin, Ireland.

Apellis Pharmaceuticals stock logo

Apellis Pharmaceuticals NASDAQ:APLS

$28.31 +1.24 (+4.58%)
Closing price 10/21/2025 04:00 PM Eastern
Extended Trading
$28.13 -0.18 (-0.64%)
As of 10/21/2025 07:58 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, and hematopoietic stem cell transplantation-associated thrombotic microangiopathy; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops APL-3007, a small interfering RNA, or siRNA, which is in a Phase 1 clinical trial, as well as an oral complement inhibitor that is in preclinical development. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. The company was incorporated in 2009 and is based in Waltham, Massachusetts.

Axsome Therapeutics stock logo

Axsome Therapeutics NASDAQ:AXSM

$131.39 -0.21 (-0.16%)
Closing price 10/21/2025 04:00 PM Eastern
Extended Trading
$130.50 -0.89 (-0.68%)
As of 10/21/2025 05:18 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.

Zai Lab stock logo

Zai Lab NASDAQ:ZLAB

$29.15 +0.41 (+1.43%)
Closing price 10/21/2025 04:00 PM Eastern
Extended Trading
$29.15 0.00 (0.00%)
As of 10/21/2025 07:21 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Zai Lab Limited develops and commercializes therapies to treat oncology, autoimmune disorders, infectious diseases, and neuroscience. Its commercial products include Zejula, an orally administered poly polymerase 1/2 inhibitor; Optune, a cancer therapy that uses electric fields tuned to specific frequencies to kill tumor cells; NUZYRA for acute bacterial skin and skin structure infections, and community acquired bacterial pneumonia; Qinlock to treat gastrointestinal stromal tumors, and VYVGART, a human IgG1 antibody fragment for myesthenia gravis. The company also develops Tumor Treating Fields, a portable device for delivery of electric fields; Repotrectinib, a tyrosine kinase inhibitor (TKI) to target ROS1 and TRK A/B/C in TKI-naïve- or -pretreated cancer patients; Tisotumab vedotin, an antibody drug conjugate; Adagrasib for treating KRAS-G12C-mutated NSCLC, colorectal cancer, and pancreatic cancer; and Bemarituzumab to treat gastric and gastroesophageal junction cancer patients. In addition, it develops Sulbactam/durlobactam, a combination of a beta-lactam antibiotic and a beta-lactamase inhibitor for the treatment of serious infections caused by Acinetobacter; KarXT for the treatment of psychiatric and neurological conditions. It has license and collaboration agreement with Tesaro, Inc. to develop, manufacture, and commercialize niraparib; NovoCure to develop and commercialize Tumor Treating Fields; Deciphera to develop and commercialize ripretinib; Paratek Bermuda Ltd. to develop, manufacture, and commercialize omadacycline; argenx, to develop and commercialize efgartigimod; BMS to develop and commercialize tisotumab vedotin and repotrectinib; Mirati to research, develop, manufacture, and commercialize adagrasib; Amgen to develop and commercialize bemarituzumab; and Innoviva to develop and commercialize Sulbactam-Durlobactam; Karuna to develop and commercialize KarXT. The company was incorporated in 2013 and is headquartered in Shanghai, China.