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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
$8.26
+3.3%
$7.42
$6.10
$28.67
$554.45M1.47307,365 shs588,833 shs
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
$15.65
+5.0%
$14.52
$10.57
$33.33
$2.18B1.32.11 million shs1.84 million shs
89BIO stock logo
ETNB
89BIO
$14.81
-0.1%
$10.73
$4.16
$15.06
$2.20B1.279.48 million shs1.13 million shs
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$23.38
+1.1%
$18.85
$10.41
$138.81
$2.26B0.516.35 million shs10.51 million shs
 The Best Nuclear Energy Stocks to Buy Cover

Nuclear energy stocks are roaring. It's the hottest energy sector of the year. Cameco Corp, Paladin Energy, and BWX Technologies were all up more than 40% in 2024. The biggest market moves could still be ahead of us, and there are seven nuclear energy stocks that could rise much higher in the next several months. To unlock these tickers, enter your email address below.

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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
+3.25%-0.84%+18.00%+2.10%-64.90%
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
+5.03%+4.96%+0.97%+1.95%-41.45%
89BIO stock logo
ETNB
89BIO
-0.13%+0.82%+72.81%+37.38%+99.87%
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
+1.12%+21.01%+32.84%+22.60%-80.47%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
$8.26
+3.3%
$7.42
$6.10
$28.67
$554.45M1.47307,365 shs588,833 shs
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
$15.65
+5.0%
$14.52
$10.57
$33.33
$2.18B1.32.11 million shs1.84 million shs
89BIO stock logo
ETNB
89BIO
$14.81
-0.1%
$10.73
$4.16
$15.06
$2.20B1.279.48 million shs1.13 million shs
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$23.38
+1.1%
$18.85
$10.41
$138.81
$2.26B0.516.35 million shs10.51 million shs
 The Best Nuclear Energy Stocks to Buy Cover

Nuclear energy stocks are roaring. It's the hottest energy sector of the year. Cameco Corp, Paladin Energy, and BWX Technologies were all up more than 40% in 2024. The biggest market moves could still be ahead of us, and there are seven nuclear energy stocks that could rise much higher in the next several months. To unlock these tickers, enter your email address below.

Get This Free Report

Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
+3.25%-0.84%+18.00%+2.10%-64.90%
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
+5.03%+4.96%+0.97%+1.95%-41.45%
89BIO stock logo
ETNB
89BIO
-0.13%+0.82%+72.81%+37.38%+99.87%
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
+1.12%+21.01%+32.84%+22.60%-80.47%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
2.50
Moderate Buy$22.22169.03% Upside
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
3.00
Buy$33.50114.06% Upside
89BIO stock logo
ETNB
89BIO
2.40
Hold$25.8174.29% Upside
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
2.07
Hold$39.0466.98% Upside

Current Analyst Ratings Breakdown

Latest BCYC, DNLI, SRPT, and ETNB Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
10/8/2025
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (D-)
10/8/2025
89BIO stock logo
ETNB
89BIO
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (D-)
10/8/2025
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
Royal Bank Of Canada
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetSector Perform$14.00 ➝ $16.00
9/27/2025
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (E+)
9/27/2025
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (D-)
9/27/2025
89BIO stock logo
ETNB
89BIO
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (D-)
9/27/2025
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingSell (D)
9/22/2025
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
BMO Capital Markets
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
UpgradeMarket PerformOutperform$50.00
9/19/2025
89BIO stock logo
ETNB
89BIO
Raymond James Financial
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
DowngradeStrong-BuyMarket Perform
9/19/2025
89BIO stock logo
ETNB
89BIO
HC Wainwright
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
DowngradeBuyNeutral$14.50
9/19/2025
89BIO stock logo
ETNB
89BIO
Wolfe Research
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
DowngradeOutperformPeer Perform
(Data available from 10/9/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
$35.28M16.23N/AN/A$11.48 per share0.72
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
$330.53M6.92N/AN/A$8.53 per share1.83
89BIO stock logo
ETNB
89BIO
N/AN/AN/AN/A$3.34 per shareN/A
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$2.48B0.92$2.46 per share9.49$15.99 per share1.46
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
-$169.03M-$3.51N/AN/AN/A-1,257.00%-32.43%-26.80%10/30/2025 (Estimated)
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
-$422.77M-$2.80N/AN/AN/AN/A-40.79%-36.39%11/5/2025 (Estimated)
89BIO stock logo
ETNB
89BIO
-$367.08M-$3.61N/AN/AN/AN/A-94.48%-80.92%11/6/2025 (Estimated)
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$235.24M-$0.87N/A2.14N/A-2.34%-1.03%-0.37%11/5/2025 (Estimated)

Latest BCYC, DNLI, SRPT, and ETNB Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
11/5/2025Q3 2025
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
-$0.76N/AN/AN/A$1.00 millionN/A
11/5/2025Q3 2025
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$0.02N/AN/AN/A$331.51 millionN/A
10/30/2025Q3 2025
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
-$1.05N/AN/AN/AN/AN/A
8/11/2025Q2 2025
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
-$0.74-$0.72+$0.02-$0.72$5.64 millionN/A
8/8/2025Q2 2025
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
-$0.95-$1.14-$0.19-$1.14$9.43 million$2.90 million
8/7/2025Q2 2025
89BIO stock logo
ETNB
89BIO
-$0.49-$0.71-$0.22-$0.71N/AN/A
8/6/2025Q2 2025
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$0.89$2.02+$1.13$1.89$530.66 million$611.09 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
N/AN/AN/AN/AN/A
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
N/AN/AN/AN/AN/A
89BIO stock logo
ETNB
89BIO
N/AN/AN/AN/AN/A
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
N/A
10.39
10.39
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
0.01
10.27
10.27
89BIO stock logo
ETNB
89BIO
0.07
15.19
15.19
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
0.84
2.89
1.81

Institutional Ownership

CompanyInstitutional Ownership
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
86.15%
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
92.92%
89BIO stock logo
ETNB
89BIO
N/A
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
86.68%

Insider Ownership

CompanyInsider Ownership
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
22.90%
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
12.50%
89BIO stock logo
ETNB
89BIO
2.60%
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
7.60%
CompanyEmployeesShares OutstandingFree FloatOptionable
Bicycle Therapeutics PLC Sponsored ADR stock logo
BCYC
Bicycle Therapeutics
24069.31 million53.44 millionOptionable
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
430146.21 million127.94 millionOptionable
89BIO stock logo
ETNB
89BIO
40148.31 million144.45 millionOptionable
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
1,37297.71 million90.29 millionOptionable

Recent News About These Companies

What's Going On Sarepta Stock On Wednesday?
Sarepta Therapeutics (SRPT) Receives a Hold from Evercore ISI
BMO upgrades Sarepta on Elevidys uptake, pipeline prospects
BMO Capital Upgrades Sarepta Therapeutics (SRPT)

New MarketBeat Followers Over Time

Media Sentiment Over Time

Bicycle Therapeutics stock logo

Bicycle Therapeutics NASDAQ:BCYC

$8.26 +0.26 (+3.25%)
Closing price 10/8/2025 04:00 PM Eastern
Extended Trading
$8.38 +0.12 (+1.45%)
As of 04:23 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Bicycle Therapeutics plc, a clinical-stage biopharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. Its product pipeline comprising BT8009, a bicycle toxin conjugate (BTC) which is in phase I/II/III clinical trial for the treatment of high nectin-4 expressing tumors; BT5528, a BTC which is in phase I/II clinical trial for the treatment of Ephrin type A receptor 2 expressing tumor; BT7480, a Bicycle TICA molecule which is in phase I/II targeting Nectin-4 and agonizing CD137; and BT7455, a Bicycle TICA molecule targeting Ephrin type A receptor 2 and CD137 and is in preclinical trial. The company also developing BT1718, a bicycle toxin conjugate (BTC), which is in Phase I/IIa clinical trials targeting tumors that express Membrane Type 1 matrix metalloprotease; and BT7401, a multivalent bicycle CD137 agonist which is in phase IIa to treat advanced solid tumors. In addition, it develops Novel anti-infective, which is in preclinical trial targeting anti-infectives disease; CNS targets, which is in preclinical trial targeting CNS disease; and Novel neuromuscular targets, which is in preclinical trial targeting neuromuscular disease. Further, the company collaborates with biopharmaceutical companies and organizations to develop programs in therapeutic areas. It has collaboration and license agreement with Bayer Consumer Care AG; Novartis Pharma AG; Cancer Research UK; Cancer Research Technology Ltd; and Oxurion NV. Bicycle Therapeutics plc was incorporated in 2009 and is headquartered in Cambridge, the United Kingdom.

Denali Therapeutics stock logo

Denali Therapeutics NASDAQ:DNLI

$15.65 +0.75 (+5.03%)
Closing price 10/8/2025 04:00 PM Eastern
Extended Trading
$15.57 -0.08 (-0.50%)
As of 05:05 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Denali Therapeutics Inc., a biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States. The company's transport vehicle (TV)-enabled programs include DNL310 ETV, an IDS enzyme replacement therapy program for MPS II; TAK-594/DNL593 which is in Phase 1/II for frontotemporal dementia-granulin; DNL126 program for MPS IIIA; and DNL622 for MPS I, as well as other preclinical programs that target amyloid beta and HER2. Its brain-penetrant small molecule programs comprise BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; SAR443820/DNL788 RIPK1 inhibitor program for CNS disease; DNL343 eIF2B Activator program for amyotrophic lateral sclerosis; and SAR443122/DNL758 RIPK1 inhibitor program for peripheral inflammatory diseases. It also provides early stage program include TAK-594/DNL593 program for FTD-GRN; DNL126 program for MPS IIIA, a Sanfilippo Syndrome A; DNL622 for MPS I which is Hurler syndrome; Antibody Transport Vehicle Amyloid beta program; Oligonucleotide Transport Vehicle platform, a novel class of biotherapeutics to address the root cause of diseases through modulation of gene expression; and other TV-enabled discovery programs. The company has collaboration agreements with Biogen MA Inc. and Biogen International GmbH; Genzyme Corporation; Takeda Pharmaceutical Company Limited; F-star Gamma Limited, F-star Biotechnologische Forschungs-und Entwicklungsges m.b.H, and F-star Biotechnology Limited; and Genentech, Inc. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

89BIO stock logo

89BIO NASDAQ:ETNB

$14.81 -0.02 (-0.13%)
Closing price 10/8/2025 04:00 PM Eastern
Extended Trading
$14.82 +0.01 (+0.10%)
As of 10/8/2025 07:11 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

89bio, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapies for the treatment of liver and cardio-metabolic diseases. Its lead product candidate is pegozafermin, a glycoPEGylated analog of fibroblast growth factor 21 for the treatment of nonalcoholic steatohepatitis; and for the treatment of severe hypertriglyceridemia. The company was incorporated in 2018 and is headquartered in San Francisco, California.

Sarepta Therapeutics stock logo

Sarepta Therapeutics NASDAQ:SRPT

$23.38 +0.26 (+1.12%)
Closing price 10/8/2025 04:00 PM Eastern
Extended Trading
$23.26 -0.11 (-0.49%)
As of 05:51 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat duchenne muscular dystrophy (duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene; and ELEVIDYS, an adeno-associated virus based gene therapy for the treatment of ambulatory pediatric patients aged 4 through 5 years with duchenne with a confirmed mutation in the duchenne gene. The company is also developing SRP-5051, a peptide conjugated PMO that binds exon 51 of dystrophin pre-mRNA; and SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Nationwide Children's Hospital; Genevant Sciences; University of Florida; Dyno Therapeutics; Hansa Biopharma; Duke University; Genethon; and StrideBio. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.