Compare Stocks: LKFT, ABVX, IONS, and PRAX

Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
ABVX Abivax	$87.98 +2.0%	$108.20	$69.81 ▼ $148.83	$7.55B	1.14	1.41 million shs	1.13 million shs
IONS Ionis Pharmaceuticals	$42.70 +0.8%	$52.24	$42.08 ▼ $86.74	$7.04B	0.38	4.01 million shs	2.03 million shs
LKFT Lakefront Biotherapeutics American Depositary Shares	$29.40 +1.2%	$28.68	$25.68 ▼ $36.24	$1.91B	0.24	344,931 shs	226,585 shs
PRAX Praxis Precision Medicines	$239.02 -1.8%	$326.50	$52.62 ▼ $392.70	$6.79B	2.79	544,516 shs	958,740 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
ABVX Abivax	-0.83%	-2.27%	-27.33%	-37.04%	-9.84%
IONS Ionis Pharmaceuticals	-2.95%	-3.68%	-21.82%	-22.57%	-39.96%
LKFT Lakefront Biotherapeutics American Depositary Shares	-1.76%	-0.92%	+8.36%	-1.46%	-14.36%
PRAX Praxis Precision Medicines	-3.20%	-13.14%	-27.27%	-23.58%	+364.92%

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
ABVX Abivax	$87.98 +2.0%	$108.20	$69.81 ▼ $148.83	$7.55B	1.14	1.41 million shs	1.13 million shs
IONS Ionis Pharmaceuticals	$42.70 +0.8%	$52.24	$42.08 ▼ $86.74	$7.04B	0.38	4.01 million shs	2.03 million shs
LKFT Lakefront Biotherapeutics American Depositary Shares	$29.40 +1.2%	$28.68	$25.68 ▼ $36.24	$1.91B	0.24	344,931 shs	226,585 shs
PRAX Praxis Precision Medicines	$239.02 -1.8%	$326.50	$52.62 ▼ $392.70	$6.79B	2.79	544,516 shs	958,740 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
ABVX Abivax	-0.83%	-2.27%	-27.33%	-37.04%	-9.84%
IONS Ionis Pharmaceuticals	-2.95%	-3.68%	-21.82%	-22.57%	-39.96%
LKFT Lakefront Biotherapeutics American Depositary Shares	-1.76%	-0.92%	+8.36%	-1.46%	-14.36%
PRAX Praxis Precision Medicines	-3.20%	-13.14%	-27.27%	-23.58%	+364.92%

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
ABVX Abivax	2.88	Moderate Buy	$156.69	78.10% Upside
IONS Ionis Pharmaceuticals	2.73	Moderate Buy	$89.20	108.90% Upside
LKFT Lakefront Biotherapeutics American Depositary Shares	2.56	Moderate Buy	$37.00	25.85% Upside
PRAX Praxis Precision Medicines	2.95	Moderate Buy	$610.95	155.61% Upside

Current Analyst Ratings Breakdown

Latest LKFT, ABVX, IONS, and PRAX Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
10/15/2026	IONS Ionis Pharmaceuticals	UBS Group Subscribe to MarketBeat All Access to unlock brokerage rankings	Upgrade	Neutral ➝ Buy	$88.00
10/14/2026	PRAX Praxis Precision Medicines	UBS Group Subscribe to MarketBeat All Access to unlock brokerage rankings	Initiated Coverage	Buy	$706.00
10/6/2026	PRAX Praxis Precision Medicines	HC Wainwright Subscribe to MarketBeat All Access to unlock brokerage rankings	Reiterated Rating	Buy	$1,201.00
10/6/2026	PRAX Praxis Precision Medicines	BTIG Research Subscribe to MarketBeat All Access to unlock brokerage rankings	Boost Price Target	Buy	$810.00 ➝ $826.00
10/2/2026	LKFT Lakefront Biotherapeutics American Depositary Shares	Weiss Ratings Subscribe to MarketBeat All Access to unlock brokerage rankings	Upgrade	Hold (C-) ➝ Hold (C)
9/24/2026	PRAX Praxis Precision Medicines	HC Wainwright Subscribe to MarketBeat All Access to unlock brokerage rankings	Reiterated Rating	Buy	$1,201.00
9/24/2026	IONS Ionis Pharmaceuticals	Oppenheimer Subscribe to MarketBeat All Access to unlock brokerage rankings	Reiterated Rating	Outperform	$85.00
9/24/2026	IONS Ionis Pharmaceuticals	HC Wainwright Subscribe to MarketBeat All Access to unlock brokerage rankings	Reiterated Rating	Buy	$100.00
9/24/2026	PRAX Praxis Precision Medicines	Needham & Company LLC Subscribe to MarketBeat All Access to unlock brokerage rankings	Reiterated Rating	Buy	$582.00
9/23/2026	LKFT Lakefront Biotherapeutics American Depositary Shares	UBS Group Subscribe to MarketBeat All Access to unlock brokerage rankings	Upgrade	Buy
9/23/2026	LKFT Lakefront Biotherapeutics American Depositary Shares	Royal Bank Of Canada Subscribe to MarketBeat All Access to unlock brokerage rankings	Upgrade	Sector Perform ➝ Outperform	$26.00 ➝ $45.00

(Data available from 10/14/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
ABVX Abivax	N/A	N/A	N/A	N/A	$6.57 per share	N/A
IONS Ionis Pharmaceuticals	$944M	7.52	N/A	N/A	$3.02 per share	14.14
LKFT Lakefront Biotherapeutics American Depositary Shares	$1.26B	1.54	$0.73 per share	40.01	$47.57 per share	0.62
PRAX Praxis Precision Medicines	$8.55M	780.52	N/A	N/A	$34.85 per share	6.86

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
ABVX Abivax	-$380.27M	-$6.06	N/A	N/A	N/A	N/A	-91.69%	-71.96%	12/21/2026 (Estimated)
IONS Ionis Pharmaceuticals	-$381.39M	-$3.46	N/A	N/A	N/A	-64.76%	-111.08%	-17.41%	11/4/2026 (Estimated)
LKFT Lakefront Biotherapeutics American Depositary Shares	$363.05M	-$1.41	N/A	N/A	N/A	N/A	N/A	N/A	N/A
PRAX Praxis Precision Medicines	-$303.27M	-$12.93	N/A	N/A	N/A	N/A	-34.15%	-32.42%	11/9/2026 (Estimated)

Latest LKFT, ABVX, IONS, and PRAX Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
11/9/2026	Q3 2026	PRAX Praxis Precision Medicines	-$3.53	N/A	N/A	N/A	$0.13 million	N/A
11/4/2026	Q3 2026	IONS Ionis Pharmaceuticals	-$1.21	N/A	N/A	N/A	$182.98 million	N/A
9/21/2026	Q2 2026	ABVX Abivax	-$0.9170	-$1.71	-$0.7930	-$1.68	$0.80 million	$1.37 million
8/10/2026	Q2 2026	LKFT Lakefront Biotherapeutics American Depositary Shares	-$0.9672	$0.03	+$0.9972	$0.0330	$7.29 million	$15.47 million
8/6/2026	Q2 2026	PRAX Praxis Precision Medicines	-$3.67	-$2.87	+$0.80	-$2.87	$1.25 million	N/A

Compare Dividends

Company	Annual Payout	Dividend Yield	5-Year Annualized Dividend Growth	Payout Ratio	Years of Consecutive Growth
ABVX Abivax	N/A	N/A	N/A	N/A	N/A
IONS Ionis Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
LKFT Lakefront Biotherapeutics American Depositary Shares	N/A	N/A	N/A	N/A	N/A
PRAX Praxis Precision Medicines	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
ABVX Abivax	N/A	5.97	5.97
IONS Ionis Pharmaceuticals	3.07	7.89	7.73
LKFT Lakefront Biotherapeutics American Depositary Shares	N/A	32.84	32.72
PRAX Praxis Precision Medicines	N/A	15.73	15.73

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
ABVX Abivax	47.91%
IONS Ionis Pharmaceuticals	93.86%
LKFT Lakefront Biotherapeutics American Depositary Shares	32.46%
PRAX Praxis Precision Medicines	67.84%

Insider Ownership

Company	Insider Ownership
ABVX Abivax	N/A
IONS Ionis Pharmaceuticals	1.81%
LKFT Lakefront Biotherapeutics American Depositary Shares	2.91%
PRAX Praxis Precision Medicines	3.00%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
ABVX Abivax	80	87.53 million	N/A	Not Optionable
IONS Ionis Pharmaceuticals	1,402	166.18 million	163.18 million	Optionable
LKFT Lakefront Biotherapeutics American Depositary Shares	1,310	65.90 million	63.98 million	Optionable
PRAX Praxis Precision Medicines	168	27.92 million	27.08 million	Optionable

LKFT, ABVX, IONS, and PRAX Headlines

Recent News About These Companies

Praxis Precision Medicines (NASDAQ:PRAX) Stock Acquired by Rep. Gilbert Ray Cisneros, Jr.

October 14 at 2:00 AM | marketbeat.com

BTIG raised its target for Praxis Precision Medicines stock to USD 826

October 13 at 11:34 PM | ad-hoc-news.deA

Praxis Precision Medicines (NASDAQ:PRAX) Stock Rating Reaffirmed as "Buy" by HC Wainwright

October 8, 2026 | americanbankingnews.com

Praxis Precision Medicines stock fell 1.21 percent as Q2 costs rose

October 7, 2026 | ad-hoc-news.deA

Praxis Precision Medicines (NASDAQ:PRAX) Given "Buy" Rating at HC Wainwright

October 6, 2026 | marketbeat.com

Praxis Precision Medicines (NASDAQ:PRAX) Stock Price Target Raised at BTIG Research

October 6, 2026 | marketbeat.com

Praxis Precision Medicines (NASDAQ:PRAX) Stock Falls 5.1% - Here's What Happened

October 5, 2026 | marketbeat.com

Praxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - October 2, 2026

October 5, 2026 | biospace.comB

JonesTrading raises target for Praxis Precision Medicines stock

October 4, 2026 | ad-hoc-news.deA

Praxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

October 2, 2026 | globenewswire.com

Praxis Precision Medicines (NASDAQ:PRAX) Earns "Buy" Rating from Needham & Company LLC

September 24, 2026 | marketbeat.com

Praxis Precision Medicines, Inc. (NASDAQ:PRAX) Given Average Recommendation of "Moderate Buy" by Brokerages

September 21, 2026 | marketbeat.com

Praxis Precision Medicines Inc (PRAX)

September 19, 2026 | in.investing.com

Praxis Precision Medicines: Still Potential Upside After Huge Rally (Rating Upgrade)

September 12, 2026 | seekingalpha.com

PRAX stock reacts to new Nasdaq inducement grants

September 4, 2026 | ad-hoc-news.deA

Praxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

September 3, 2026 | globenewswire.com

S&P 500 Futures Drop in Premarket Trading; Praxis Precision Meds, Science Applications Lead

August 31, 2026 | barrons.com

Praxis Precision Medicines Could Be Approaching 'Perfect Trifecta,' Oppenheimer Says

August 17, 2026 | finance.yahoo.com

RBC Capital Reaffirms Their Buy Rating on Praxis Precision Medicines (PRAX)

August 11, 2026 | theglobeandmail.com

4 Biotech Stocks With Major Second-Half Pipeline Catalysts This Year

August 11, 2026 | zacks.com

Is Praxis (PRAX) Trading Bigger Losses for Long-Run CNS Ambition With Its Cash War Chest?

August 8, 2026 | finance.yahoo.com

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LKFT, ABVX, IONS, and PRAX Company Descriptions

Abivax NASDAQ:ABVX

$87.98 +1.76 (+2.04%)

Closing price 04:00 PM Eastern

Extended Trading

$87.98 -0.01 (-0.01%)

As of 07:30 PM Eastern

ABIVAX Société Anonyme, a clinical-stage biotechnology company, focuses on developing therapeutics that harness the body's natural regulatory mechanisms to stablize the immune response in patients with chronic inflammatory diseases. The company is evaluating its lead drug candidate, obefazimod, in Phase 3 clinical trials for the treatment of moderately to severely active ulcerative colitis in adults. ABIVAX Société Anonyme was incorporated in 2013 and is headquartered in Paris, France.

Ionis Pharmaceuticals NASDAQ:IONS

$42.70 +0.32 (+0.76%)

Closing price 04:00 PM Eastern

Extended Trading

$42.72 +0.02 (+0.05%)

As of 07:48 PM Eastern

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.

Lakefront Biotherapeutics American Depositary Shares NASDAQ:LKFT

$29.40 +0.35 (+1.20%)

As of 04:00 PM Eastern

Galapagos NV, an integrated biopharmaceutical company, engages in the discovery, development, and commercialization of various medicines for high unmet medical need. Its pipeline products include filgotinib, a JAK1 inhibitor that is in various phases of clinical trials for the treatment of rheumatoid arthritis, Crohn's disease, ulcerative colitis, small bowel CD, fistulizing CD, ankylosing spondylitis, psoriatic arthritis, and uveitis. The company's pipeline products also comprise GLPG1972 that has completed Phase 2b trial for treating osteoarthritis; Toledo molecules, including GLPG3970, GLPG4399, and GLPG4876 for inflammation; and GLPG4716 and Ziritaxestat to treat idiopathic pulmonary fibrosis. In addition, its other pipeline products include GLPG2737, a cystic fibrosis transmembrane conductance regulator that is in Phase 2 clinical trials to treat patients with autosomal dominant polycystic kidney disease; and GLPG0555, a JAK1 inhibitor, which is in Phase 1b for treatment of patients with osteoarthritis. The company has collaboration agreements with Gilead Sciences, Inc.; AbbVie S.à r.l.; and Novartis Pharma AG. Galapagos NV was incorporated in 1999 and is headquartered in Mechelen, Belgium.

Praxis Precision Medicines NASDAQ:PRAX

$239.02 -4.32 (-1.78%)

Closing price 04:00 PM Eastern

Extended Trading

$241.48 +2.46 (+1.03%)

As of 07:30 PM Eastern

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. It is developing ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase III clinical trial for the treatment of essential tremor; PRAX-562 for the treatment of pediatric patients with developmental and epileptic encephalopathies (DEE); and PRAX-628 to treat focal epilepsy. The company also develops PRAX-222 for the treatment of pediatric patients with early-onset SCN2A-DEE; PRAX-020 to treat KCNT1 related epilepsies; PRAX-080 for the treatment of PCDH19; and PRAX-090 and PRAX-100 for SYNGAP1 and SCN2A-LoF. It has a license agreement with RogCon Inc.; a research collaboration and license agreement with Ionis Pharmaceuticals, Inc.; a strategic collaboration and license agreement with UCB Biopharma SRL; and collaboration with The Florey Institute to develop three novel ASOs. The company was incorporated in 2015 and is based in Boston, Massachusetts.

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Compare Stocks

Comparative Price Performance Over Time

Compare Price & Volume

Compare Price Performance

Compare Price & Volume

Compare Price Performance

Compare Analyst Forecasts

Current Analyst Ratings Breakdown

Latest LKFT, ABVX, IONS, and PRAX Analyst Ratings

Compare Sales & Book Value

Compare Profitability & Earnings

Latest LKFT, ABVX, IONS, and PRAX Earnings

Compare Dividends

Compare Debt

Compare Ownership

Institutional Ownership

Insider Ownership

Compare Miscellaneous Stats

LKFT, ABVX, IONS, and PRAX Headlines

Recent News About These Companies

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

LKFT, ABVX, IONS, and PRAX Company Descriptions

Abivax NASDAQ:ABVX

Ionis Pharmaceuticals NASDAQ:IONS

Lakefront Biotherapeutics American Depositary Shares NASDAQ:LKFT

Praxis Precision Medicines NASDAQ:PRAX

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Latest LKFT, ABVX, IONS, and PRAX Analyst Ratings

Compare Sales & Book Value

Compare Profitability & Earnings

Latest LKFT, ABVX, IONS, and PRAX Earnings

Compare Dividends

Compare Debt

Compare Ownership

Institutional Ownership

Insider Ownership

Compare Miscellaneous Stats

LKFT, ABVX, IONS, and PRAX Headlines

Recent News About These Companies

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

LKFT, ABVX, IONS, and PRAX Company Descriptions

Abivax NASDAQ:ABVX

Ionis Pharmaceuticals NASDAQ:IONS

Lakefront Biotherapeutics American Depositary Shares NASDAQ:LKFT

Praxis Precision Medicines NASDAQ:PRAX

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