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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ACIU NASDAQ:AKBA NASDAQ:PLRX NASDAQ:PRLD On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeACIUAC Immune$2.83$2.94$1.60▼$4.00$288.02M1.65270,589 shs78,142 shsAKBAAkebia Therapeutics$1.02$1.33$0.88▼$4.08$273.62M0.355.40 million shs2.32 million shsPLRXPliant Therapeutics$1.21$1.26$1.09▼$1.95$74.92M1.2437,533 shs212,117 shsPRLDPrelude Therapeutics$4.27$4.11$0.75▼$5.54$269.02M1.11509,404 shs241,565 shsBeginner's Guide To Retirement StocksClick the link to see MarketBeat's list of seven best retirement stocks and why they should be in your portfolio. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceACIUAC Immune0.00%+2.17%-0.35%+4.04%+67.46%AKBAAkebia Therapeutics0.00%+0.99%-28.67%-17.74%-64.34%PLRXPliant Therapeutics0.00%+2.54%-2.42%-4.72%-6.20%PRLDPrelude Therapeutics0.00%-1.61%-9.15%+49.30%+381.83%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeACIUAC Immune$2.83$2.94$1.60▼$4.00$288.02M1.65270,589 shs78,142 shsAKBAAkebia Therapeutics$1.02$1.33$0.88▼$4.08$273.62M0.355.40 million shs2.32 million shsPLRXPliant Therapeutics$1.21$1.26$1.09▼$1.95$74.92M1.2437,533 shs212,117 shsPRLDPrelude Therapeutics$4.27$4.11$0.75▼$5.54$269.02M1.11509,404 shs241,565 shsBeginner's Guide To Retirement StocksClick the link to see MarketBeat's list of seven best retirement stocks and why they should be in your portfolio. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceACIUAC Immune0.00%+2.17%-0.35%+4.04%+67.46%AKBAAkebia Therapeutics0.00%+0.99%-28.67%-17.74%-64.34%PLRXPliant Therapeutics0.00%+2.54%-2.42%-4.72%-6.20%PRLDPrelude Therapeutics0.00%-1.61%-9.15%+49.30%+381.83%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceACIUAC Immune 2.25Hold$7.50165.02% UpsideAKBAAkebia Therapeutics 2.20Hold$4.67357.52% UpsidePLRXPliant Therapeutics 1.80Reduce$3.00147.93% UpsidePRLDPrelude Therapeutics 2.40Hold$7.6779.55% UpsideCurrent Analyst Ratings BreakdownLatest PLRX, AKBA, ACIU, and PRLD Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/8/2026ACIUAC Immune Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingDowngradeSell (D-) ➝ Sell (E+)5/6/2026AKBAAkebia Therapeutics Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingSell (E+)5/6/2026AKBAAkebia Therapeutics Zacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingDowngradeHold ➝ Strong Sell5/4/2026ACIUAC Immune BTIG ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$8.005/4/2026PRLDPrelude Therapeutics D. Boral CapitalSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageBuy$9.005/1/2026PRLDPrelude Therapeutics Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeSell (E+) ➝ Sell (D-)4/28/2026PRLDPrelude Therapeutics Zacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeHold4/27/2026PRLDPrelude Therapeutics HC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetBuy$5.00 ➝ $8.004/21/2026PLRXPliant Therapeutics Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingSell (E+)4/20/2026ACIUAC Immune Weiss RatingsSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingSell (D-)4/7/2026AKBAAkebia Therapeutics Zacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeStrong Sell ➝ Hold(Data available from 5/26/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookACIUAC Immune$4.31M66.82N/AN/A$0.40 per share7.08AKBAAkebia Therapeutics$236.20M1.16N/AN/A$0.10 per share10.20PLRXPliant Therapeutics$1.58M47.42N/AN/A$2.67 per share0.45PRLDPrelude Therapeutics$12.14M22.16N/AN/A$0.96 per share4.45Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateACIUAC Immune-$85.03M-$0.82N/A3.22N/A-1,788.02%-125.26%-40.85%8/4/2026 (Estimated)AKBAAkebia Therapeutics-$5.34M-$0.08N/AN/AN/A-8.83%-62.72%-5.66%8/6/2026 (Estimated)PLRXPliant Therapeutics-$149.34M-$1.84N/AN/AN/AN/A-58.11%-44.37%8/6/2026 (Estimated)PRLDPrelude Therapeutics-$99.50M-$1.00N/AN/AN/AN/A-118.24%-66.12%8/13/2026 (Estimated)Latest PLRX, AKBA, ACIU, and PRLD EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/12/2026Q1 2026PRLDPrelude Therapeutics-$0.27-$0.13+$0.14-$0.13$4.58 million$4.58 million5/11/2026Q1 2026PLRXPliant Therapeutics-$0.36-$0.32+$0.04-$0.32N/AN/A5/7/2026Q1 2026AKBAAkebia Therapeutics-$0.01-$0.03-$0.02-$0.03$51.67 million$53.54 million4/30/2026Q1 2026ACIUAC Immune-$0.20-$0.19+$0.01-$0.19$0.33 million$1.40 million3/13/2026Q4 2025ACIUAC Immune-$0.19-$0.18+$0.01-$0.18$1.14 million$0.44 million3/11/2026Q4 2025PLRXPliant Therapeutics-$0.44-$0.35+$0.09-$0.38N/AN/A3/10/2026Q4 2025PRLDPrelude Therapeutics-$0.33-$0.20+$0.13-$0.20$20.50 million$5.64 million2/26/2026Q4 2025AKBAAkebia Therapeutics-$0.03-$0.05-$0.02-$0.05$48.37 million$57.62 millionCompare DividendsCompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive GrowthACIUAC ImmuneN/AN/AN/AN/AN/AAKBAAkebia TherapeuticsN/AN/AN/AN/AN/APLRXPliant TherapeuticsN/AN/AN/AN/AN/APRLDPrelude TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioACIUAC Immune0.110.871.02AKBAAkebia Therapeutics1.331.401.33PLRXPliant TherapeuticsN/A16.8916.89PRLDPrelude TherapeuticsN/A2.032.03Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipACIUAC Immune51.36%AKBAAkebia Therapeutics33.92%PLRXPliant Therapeutics97.30%PRLDPrelude Therapeutics79.72%Insider OwnershipCompanyInsider OwnershipACIUAC Immune4.60%AKBAAkebia Therapeutics4.30%PLRXPliant Therapeutics8.00%PRLDPrelude Therapeutics49.20%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableACIUAC Immune140101.77 million97.09 millionOptionableAKBAAkebia Therapeutics430268.26 million256.72 millionOptionablePLRXPliant Therapeutics9061.92 million56.97 millionOptionablePRLDPrelude Therapeutics12063.00 million32.01 millionOptionablePLRX, AKBA, ACIU, and PRLD HeadlinesRecent News About These CompaniesEarnings Beat: Prelude Therapeutics Incorporated (NASDAQ:PRLD) Just Beat Analyst Forecasts, And Analysts Have Been Lifting Their ForecastsMay 16, 2026 | finance.yahoo.comPrelude Therapeutics (PRLD) price target increased by 11.49% to 7.01May 14, 2026 | msn.comPrelude Therapeutics Initiates Phase 1 Study of PRT12396 and Provides R&D Pipeline UpdateMay 12, 2026 | quiverquant.comQPrelude Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate UpdateMay 12, 2026 | globenewswire.comWall Street Analysts Think Prelude Therapeutics (PRLD) Could Surge 33.59%: Read This Before Placing a BetMay 8, 2026 | zacks.comD Boral Capital initiates coverage of Prelude Therapeutics (PRLD) with buy recommendationMay 5, 2026 | msn.comPrelude Therapeutics Incorporated (NASDAQ:PRLD) Given Consensus Recommendation of "Hold" by AnalystsMay 4, 2026 | marketbeat.comPrelude Therapeutics (NASDAQ:PRLD) Coverage Initiated by Analysts at D. Boral CapitalMay 4, 2026 | marketbeat.comPrelude Therapeutics (PRLD) Presents Preclinical Data for KAT6A Degarader PRT13722 in Breast CancerMay 1, 2026 | uk.finance.yahoo.com9 Best Biotech Penny Stocks to Buy in 2026April 30, 2026 | insidermonkey.comPrelude Therapeutics (NASDAQ:PRLD) Rating Increased to Hold at Zacks ResearchApril 30, 2026 | marketbeat.comShort Interest in Prelude Therapeutics Incorporated (NASDAQ:PRLD) Decreases By 22.1%April 29, 2026 | marketbeat.comPrelude Therapeutics (PRLD) price target increased by 19.35% to 6.29April 29, 2026 | msn.comHC Wainwright Issues Positive Estimate for PRLD EarningsApril 29, 2026 | marketbeat.comPrelude Therapeutics (PRLD) Expected to Announce Quarterly Earnings on TuesdayApril 28, 2026 | marketbeat.comHC Wainwright Issues Positive Forecast for Prelude Therapeutics (NASDAQ:PRLD) Stock PriceApril 27, 2026 | marketbeat.comPrelude Therapeutics director David P. Bonita acquires $12.5 million in stockApril 24, 2026 | investing.comInsider Buying: Prelude Therapeutics (NASDAQ:PRLD) Director Acquires 2,815,315 Shares of StockApril 24, 2026 | insidertrades.comPrelude Therapeutics Presents Preclinical Data from Development Candidate, PRT13722, a First-in-Class, Orally Bioavailable, Potent and Highly Selective KAT6A Degrader at ...April 20, 2026 | finance.yahoo.comPrelude Therapeutics prices $90M equity offeringApril 20, 2026 | seekingalpha.comPrelude Therapeutics Announces Pricing of $90.0 Million Underwritten OfferingApril 20, 2026 | globenewswire.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimePLRX, AKBA, ACIU, and PRLD Company DescriptionsAC Immune NASDAQ:ACIU$2.83 0.00 (0.00%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$2.84 +0.00 (+0.18%) As of 05/22/2026 05:23 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. Its SupraAntigen and Morphomer platforms are designed to generate vaccines, antibodies, and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. The company is developing Crenezumab, a humanized, conformation-specific monoclonal antibody, which is in Phase II clinical studies trial for the treatment of Alzheimer's disease (AD). It is also developing ACI-24, an anti-Abeta vaccine candidate that is in Phase II clinical study for AD, as well as completed Phase Ib clinical study for Down syndrome; ACI-35, an anti-Tau vaccine candidate that is in Phase Ib/2a clinical study; and Tau- positron emission tomography (PET) imaging tracer, which is in Phase II clinical study. In addition, the company is researching and developing small molecule Tau aggregation inhibitors for AD and NeuroOrphan indications. Further, it has discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. AC Immune SA has license agreements and collaborations with Genentech, Inc.; Biogen International GmbH; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; Eli Lilly and Company; and WuXi Biologics. The company was incorporated in 2003 and is headquartered in Lausanne, Switzerland.Akebia Therapeutics NASDAQ:AKBA$1.02 0.00 (0.00%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$1.01 -0.01 (-0.49%) As of 05/22/2026 06:28 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. The company's lead product investigational product candidate is Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, which is in Phase III development for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent and non-dialysis dependent patients. It offers Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD on dialysis; and the treatment of iron deficiency anemia in adult patients with CKD not on dialysis. The company's product pipeline includes AKB-9090, a drug targeting critical-care indications; and AKB-10108, a drug targeting conditions related to premature birth. It has collaboration agreements with Mitsubishi Tanabe Pharma Corporation for the development and commercialization of vadadustat in Japan and other Asian countries, as well as research and license agreement with Janssen Pharmaceutica NV for the development and commercialization of hypoxia-inducible factor prolyl hydroxylase targeted compounds worldwide. Akebia Therapeutics, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.Pliant Therapeutics NASDAQ:PLRX$1.21 0.00 (0.00%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$1.23 +0.02 (+1.98%) As of 05/22/2026 06:25 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Pliant Therapeutics, Inc., a clinical stage biopharmaceutical company, discovers, develops, and commercializes novel therapies for the treatment of fibrosis and related diseases in the United States. The company's lead candidate is bexotegrast, an oral, small-molecule, dual selective inhibitor of avß6 and avß1 integrins, which is in phase 2b trials for idiopathic pulmonary fibrosis and in phase 2a trial for primary sclerosing cholangitis. It also develops PLN-1474, an oral, small-molecule selective inhibitor of avß1 for the treatment of liver fibrosis associated with nonalcoholic steatohepatitis; PLN-101095, a dual inhibitor of integrins avß8 and avß1 for the treatment of solid tumors; and PLN-101325 for treatment of muscular dystrophies. Pliant Therapeutics, Inc. was incorporated in 2015 and is based in South San Francisco, California.Prelude Therapeutics NASDAQ:PRLD$4.27 0.00 (0.00%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$4.26 0.00 (-0.12%) As of 05/22/2026 07:24 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.Prelude Therapeutics Incorporated, a clinical-stage biopharmaceutical company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT1419, a myeloid cell leukemia-1 inhibitor, which is in Phase 1 clinical trial for the treatment of selected relapsed/refractory myeloid or B-cell malignancies; PRT2527, a cyclin-dependent kinase, which is in Phase 1 clinical trial for the treatment of advanced solid tumors; PRT3645, a cyclin-dependent kinase 4/6 inhibitor, which is in Phase 1 clinical trial for the treatment of advanced and metastatic solid tumors; and PRT3879, a SMARCA2 selective protein degrader, which is in Phase 2/3 clinical trial for the treatment of advanced and metastatic solid tumors with loss of SMARCA4 due to truncating mutation and/or deletion. The company's CDK9 program is a regulator of cancer-promoting transcriptional programs, including MCL1, MYC and MYB. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware. 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