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Compare stocks with our powerful stock comparison tool. Analyze fundamentals, price performance, and key financial indicators to make informed investment decisions. Our tool lets you compare up to ten stocks side by side based on Performance Charts, Price & Volume, MarketRank™, Analyst Ratings, Sales & Book Value, Profitability & Earnings, Dividends, Debt, Ownership, Headlines, and more. Simply enter up to ten stock symbols (e.g., BAC, JPM, WFC, C, GS) to get started and uncover top investment opportunities.

CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
AC Immune stock logo
ACIU
AC Immune
$2.83
$2.94
$1.60
$4.00
$288.02M1.65270,589 shs78,142 shs
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
$1.02
$1.33
$0.88
$4.08
$273.62M0.355.40 million shs2.32 million shs
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$1.21
$1.26
$1.09
$1.95
$74.92M1.2437,533 shs212,117 shs
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
$4.27
$4.11
$0.75
$5.54
$269.02M1.11509,404 shs241,565 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
AC Immune stock logo
ACIU
AC Immune
0.00%+2.17%-0.35%+4.04%+67.46%
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
0.00%+0.99%-28.67%-17.74%-64.34%
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
0.00%+2.54%-2.42%-4.72%-6.20%
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
0.00%-1.61%-9.15%+49.30%+381.83%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
AC Immune stock logo
ACIU
AC Immune
$2.83
$2.94
$1.60
$4.00
$288.02M1.65270,589 shs78,142 shs
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
$1.02
$1.33
$0.88
$4.08
$273.62M0.355.40 million shs2.32 million shs
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$1.21
$1.26
$1.09
$1.95
$74.92M1.2437,533 shs212,117 shs
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
$4.27
$4.11
$0.75
$5.54
$269.02M1.11509,404 shs241,565 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
AC Immune stock logo
ACIU
AC Immune
0.00%+2.17%-0.35%+4.04%+67.46%
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
0.00%+0.99%-28.67%-17.74%-64.34%
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
0.00%+2.54%-2.42%-4.72%-6.20%
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
0.00%-1.61%-9.15%+49.30%+381.83%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
AC Immune stock logo
ACIU
AC Immune
2.25
Hold$7.50165.02% Upside
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
2.20
Hold$4.67357.52% Upside
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
1.80
Reduce$3.00147.93% Upside
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
2.40
Hold$7.6779.55% Upside

Current Analyst Ratings Breakdown

Latest PLRX, AKBA, ACIU, and PRLD Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
5/8/2026
AC Immune stock logo
ACIU
AC Immune
DowngradeSell (D-)Sell (E+)
5/6/2026
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
Reiterated RatingSell (E+)
5/6/2026
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
DowngradeHoldStrong Sell
5/4/2026
AC Immune stock logo
ACIU
AC Immune
Reiterated RatingBuy$8.00
5/4/2026
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
Initiated CoverageBuy$9.00
5/1/2026
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
UpgradeSell (E+)Sell (D-)
4/28/2026
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
UpgradeHold
4/27/2026
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
Boost Price TargetBuy$5.00 ➝ $8.00
4/21/2026
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
Reiterated RatingSell (E+)
4/20/2026
AC Immune stock logo
ACIU
AC Immune
Reiterated RatingSell (D-)
4/7/2026
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
UpgradeStrong SellHold
(Data available from 5/26/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
AC Immune stock logo
ACIU
AC Immune
$4.31M66.82N/AN/A$0.40 per share7.08
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
$236.20M1.16N/AN/A$0.10 per share10.20
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$1.58M47.42N/AN/A$2.67 per share0.45
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
$12.14M22.16N/AN/A$0.96 per share4.45
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
AC Immune stock logo
ACIU
AC Immune
-$85.03M-$0.82N/A3.22N/A-1,788.02%-125.26%-40.85%8/4/2026 (Estimated)
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
-$5.34M-$0.08N/AN/AN/A-8.83%-62.72%-5.66%8/6/2026 (Estimated)
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
-$149.34M-$1.84N/AN/AN/AN/A-58.11%-44.37%8/6/2026 (Estimated)
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
-$99.50M-$1.00N/AN/AN/AN/A-118.24%-66.12%8/13/2026 (Estimated)

Latest PLRX, AKBA, ACIU, and PRLD Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/12/2026Q1 2026
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
-$0.27-$0.13+$0.14-$0.13$4.58 million$4.58 million
5/11/2026Q1 2026
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
-$0.36-$0.32+$0.04-$0.32N/AN/A
5/7/2026Q1 2026
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
-$0.01-$0.03-$0.02-$0.03$51.67 million$53.54 million
4/30/2026Q1 2026
AC Immune stock logo
ACIU
AC Immune
-$0.20-$0.19+$0.01-$0.19$0.33 million$1.40 million
3/13/2026Q4 2025
AC Immune stock logo
ACIU
AC Immune
-$0.19-$0.18+$0.01-$0.18$1.14 million$0.44 million
3/11/2026Q4 2025
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
-$0.44-$0.35+$0.09-$0.38N/AN/A
3/10/2026Q4 2025
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
-$0.33-$0.20+$0.13-$0.20$20.50 million$5.64 million
2/26/2026Q4 2025
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
-$0.03-$0.05-$0.02-$0.05$48.37 million$57.62 million
CompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive Growth
AC Immune stock logo
ACIU
AC Immune
N/AN/AN/AN/AN/A
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
N/AN/AN/AN/AN/A
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
N/AN/AN/AN/AN/A
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
AC Immune stock logo
ACIU
AC Immune
0.11
0.87
1.02
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
1.33
1.40
1.33
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
N/A
16.89
16.89
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
N/A
2.03
2.03

Institutional Ownership

CompanyInstitutional Ownership
AC Immune stock logo
ACIU
AC Immune
51.36%
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
33.92%
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
97.30%
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
79.72%

Insider Ownership

CompanyInsider Ownership
AC Immune stock logo
ACIU
AC Immune
4.60%
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
4.30%
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
8.00%
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
49.20%
CompanyEmployeesShares OutstandingFree FloatOptionable
AC Immune stock logo
ACIU
AC Immune
140101.77 million97.09 millionOptionable
Akebia Therapeutics, Inc. stock logo
AKBA
Akebia Therapeutics
430268.26 million256.72 millionOptionable
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
9061.92 million56.97 millionOptionable
Prelude Therapeutics Incorporated stock logo
PRLD
Prelude Therapeutics
12063.00 million32.01 millionOptionable

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AC Immune stock logo

AC Immune NASDAQ:ACIU

$2.83 0.00 (0.00%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$2.84 +0.00 (+0.18%)
As of 05/22/2026 05:23 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. Its SupraAntigen and Morphomer platforms are designed to generate vaccines, antibodies, and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. The company is developing Crenezumab, a humanized, conformation-specific monoclonal antibody, which is in Phase II clinical studies trial for the treatment of Alzheimer's disease (AD). It is also developing ACI-24, an anti-Abeta vaccine candidate that is in Phase II clinical study for AD, as well as completed Phase Ib clinical study for Down syndrome; ACI-35, an anti-Tau vaccine candidate that is in Phase Ib/2a clinical study; and Tau- positron emission tomography (PET) imaging tracer, which is in Phase II clinical study. In addition, the company is researching and developing small molecule Tau aggregation inhibitors for AD and NeuroOrphan indications. Further, it has discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. AC Immune SA has license agreements and collaborations with Genentech, Inc.; Biogen International GmbH; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; Eli Lilly and Company; and WuXi Biologics. The company was incorporated in 2003 and is headquartered in Lausanne, Switzerland.

Akebia Therapeutics stock logo

Akebia Therapeutics NASDAQ:AKBA

$1.02 0.00 (0.00%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$1.01 -0.01 (-0.49%)
As of 05/22/2026 06:28 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. The company's lead product investigational product candidate is Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, which is in Phase III development for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent and non-dialysis dependent patients. It offers Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD on dialysis; and the treatment of iron deficiency anemia in adult patients with CKD not on dialysis. The company's product pipeline includes AKB-9090, a drug targeting critical-care indications; and AKB-10108, a drug targeting conditions related to premature birth. It has collaboration agreements with Mitsubishi Tanabe Pharma Corporation for the development and commercialization of vadadustat in Japan and other Asian countries, as well as research and license agreement with Janssen Pharmaceutica NV for the development and commercialization of hypoxia-inducible factor prolyl hydroxylase targeted compounds worldwide. Akebia Therapeutics, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.

Pliant Therapeutics stock logo

Pliant Therapeutics NASDAQ:PLRX

$1.21 0.00 (0.00%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$1.23 +0.02 (+1.98%)
As of 05/22/2026 06:25 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Pliant Therapeutics, Inc., a clinical stage biopharmaceutical company, discovers, develops, and commercializes novel therapies for the treatment of fibrosis and related diseases in the United States. The company's lead candidate is bexotegrast, an oral, small-molecule, dual selective inhibitor of avß6 and avß1 integrins, which is in phase 2b trials for idiopathic pulmonary fibrosis and in phase 2a trial for primary sclerosing cholangitis. It also develops PLN-1474, an oral, small-molecule selective inhibitor of avß1 for the treatment of liver fibrosis associated with nonalcoholic steatohepatitis; PLN-101095, a dual inhibitor of integrins avß8 and avß1 for the treatment of solid tumors; and PLN-101325 for treatment of muscular dystrophies. Pliant Therapeutics, Inc. was incorporated in 2015 and is based in South San Francisco, California.

Prelude Therapeutics stock logo

Prelude Therapeutics NASDAQ:PRLD

$4.27 0.00 (0.00%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$4.26 0.00 (-0.12%)
As of 05/22/2026 07:24 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Prelude Therapeutics Incorporated, a clinical-stage biopharmaceutical company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT1419, a myeloid cell leukemia-1 inhibitor, which is in Phase 1 clinical trial for the treatment of selected relapsed/refractory myeloid or B-cell malignancies; PRT2527, a cyclin-dependent kinase, which is in Phase 1 clinical trial for the treatment of advanced solid tumors; PRT3645, a cyclin-dependent kinase 4/6 inhibitor, which is in Phase 1 clinical trial for the treatment of advanced and metastatic solid tumors; and PRT3879, a SMARCA2 selective protein degrader, which is in Phase 2/3 clinical trial for the treatment of advanced and metastatic solid tumors with loss of SMARCA4 due to truncating mutation and/or deletion. The company's CDK9 program is a regulator of cancer-promoting transcriptional programs, including MCL1, MYC and MYB. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.