Compare Stocks: RYTM, INSM, BNTX, and INCY

Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
BNTX BioNTech	$102.88 -0.9%	$96.13	$79.52 ▼ $124.00	$26.02B	1.29	1.12 million shs	1.16 million shs
INCY Incyte	$128.00 -0.6%	$120.20	$81.09 ▼ $132.60	$25.95B	0.77	1.73 million shs	900,291 shs
INSM Insmed	$126.68 +0.0%	$114.95	$90.39 ▼ $212.75	$27.66B	0.82	2.99 million shs	1.88 million shs
RYTM Rhythm Pharmaceuticals	$104.89 -0.5%	$109.80	$74.50 ▼ $122.20	$7.19B	1.97	762,280 shs	269,768 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
BNTX BioNTech	+1.83%	-7.77%	+12.53%	+15.87%	+3.17%
INCY Incyte	+3.06%	+0.55%	+8.78%	+27.25%	+49.84%
INSM Insmed	+4.21%	+1.80%	+28.62%	+20.69%	-12.85%
RYTM Rhythm Pharmaceuticals	+0.65%	-5.77%	+2.57%	+20.33%	+1.16%

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
BNTX BioNTech	$102.88 -0.9%	$96.13	$79.52 ▼ $124.00	$26.02B	1.29	1.12 million shs	1.16 million shs
INCY Incyte	$128.00 -0.6%	$120.20	$81.09 ▼ $132.60	$25.95B	0.77	1.73 million shs	900,291 shs
INSM Insmed	$126.68 +0.0%	$114.95	$90.39 ▼ $212.75	$27.66B	0.82	2.99 million shs	1.88 million shs
RYTM Rhythm Pharmaceuticals	$104.89 -0.5%	$109.80	$74.50 ▼ $122.20	$7.19B	1.97	762,280 shs	269,768 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
BNTX BioNTech	+1.83%	-7.77%	+12.53%	+15.87%	+3.17%
INCY Incyte	+3.06%	+0.55%	+8.78%	+27.25%	+49.84%
INSM Insmed	+4.21%	+1.80%	+28.62%	+20.69%	-12.85%
RYTM Rhythm Pharmaceuticals	+0.65%	-5.77%	+2.57%	+20.33%	+1.16%

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
BNTX BioNTech	2.74	Moderate Buy	$127.44	23.87% Upside
INCY Incyte	2.56	Moderate Buy	$123.10	-3.83% Downside
INSM Insmed	3.00	Buy	$205.52	62.24% Upside
RYTM Rhythm Pharmaceuticals	2.74	Moderate Buy	$141.12	34.54% Upside

Current Analyst Ratings Breakdown

Latest RYTM, INSM, BNTX, and INCY Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
9/1/2026	INCY Incyte	BMO Capital Markets Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Reiterated Rating	Market Perform
8/31/2026	BNTX BioNTech	Canaccord Genuity Group Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Lower Price Target	Buy	$142.00 ➝ $136.00
8/28/2026	RYTM Rhythm Pharmaceuticals	Deutsche Bank Aktiengesellschaft Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Initiated Coverage	Hold	$120.00
8/24/2026	INCY Incyte	TD Cowen Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Upgrade	Strong-Buy
8/20/2026	INCY Incyte	Benchmark Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Reiterated Rating	Buy
8/20/2026	INCY Incyte	Canaccord Genuity Group Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Initiated Coverage	Buy	$152.00
8/20/2026	INCY Incyte	HC Wainwright Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Reiterated Rating	Buy	$150.00
8/17/2026	INCY Incyte	Piper Sandler Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Boost Price Target	Overweight	$110.00 ➝ $130.00
8/13/2026	INCY Incyte	Sanford C. Bernstein Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Reiterated Rating	Market Perform	$104.00
8/10/2026	INSM Insmed	Truist Financial Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Reiterated Rating	Buy	$185.00 ➝ $195.00
8/10/2026	INSM Insmed	HC Wainwright Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating	Reiterated Rating	Buy

(Data available from 9/3/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
BNTX BioNTech	$3.25B	8.01	$1.35 per share	76.36	$81.64 per share	1.26
INCY Incyte	$5.14B	5.05	$6.33 per share	20.23	$31.30 per share	4.09
INSM Insmed	$1.14B	24.32	N/A	N/A	$3.47 per share	36.51
RYTM Rhythm Pharmaceuticals	$189.76M	37.88	N/A	N/A	$1.50 per share	69.93

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
BNTX BioNTech	-$1.29B	-$7.83	N/A	N/A	N/A	-63.54%	-6.86%	-6.00%	11/3/2026 (Estimated)
INCY Incyte	$1.29B	$7.85	16.31	16.14	3.63	27.71%	29.93%	22.88%	10/27/2026 (Estimated)
INSM Insmed	-$1.28B	-$4.11	N/A	48.54	N/A	-76.94%	-123.94%	-44.30%	10/29/2026 (Estimated)
RYTM Rhythm Pharmaceuticals	-$196.54M	-$3.11	N/A	N/A	N/A	-85.59%	-159.87%	-44.00%	11/3/2026 (Estimated)

Latest RYTM, INSM, BNTX, and INCY Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/6/2026	Q2 2026	INSM Insmed	-$0.6724	-$0.06	+$0.6124	-$0.06	$395.50 million	$425.49 million
8/4/2026	Q2 2026	BNTX BioNTech	-$2.3983	-$2.5340	-$0.1357	-$3.70	$180.18 million	$122.31 million
8/4/2026	Q2 2026	RYTM Rhythm Pharmaceuticals	-$0.8072	-$0.73	+$0.0772	-$0.73	$67.66 million	$71.26 million
7/28/2026	Q2 2026	INCY Incyte	$2.15	$3.09	+$0.94	$2.81	$1.50 billion	$1.67 billion

Compare Dividends

Company	Annual Payout	Dividend Yield	5-Year Annualized Dividend Growth	Payout Ratio	Years of Consecutive Growth
BNTX BioNTech	N/A	N/A	N/A	N/A	N/A
INCY Incyte	N/A	N/A	N/A	N/A	N/A
INSM Insmed	N/A	N/A	N/A	N/A	N/A
RYTM Rhythm Pharmaceuticals	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
BNTX BioNTech	0.01	7.85	7.80
INCY Incyte	N/A	4.59	4.51
INSM Insmed	0.74	3.72	3.40
RYTM Rhythm Pharmaceuticals	N/A	3.45	3.20

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
BNTX BioNTech	15.52%
INCY Incyte	96.97%
INSM Insmed	N/A
RYTM Rhythm Pharmaceuticals	N/A

Insider Ownership

Company	Insider Ownership
BNTX BioNTech	19.20%
INCY Incyte	16.20%
INSM Insmed	2.10%
RYTM Rhythm Pharmaceuticals	5.90%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
BNTX BioNTech	7,807	252.88 million	204.33 million	Optionable
INCY Incyte	2,844	202.70 million	169.86 million	Optionable
INSM Insmed	1,664	218.38 million	213.80 million	Optionable
RYTM Rhythm Pharmaceuticals	140	68.53 million	64.49 million	Optionable

RYTM, INSM, BNTX, and INCY Headlines

Recent News About These Companies

UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Has $57.16 Million Holdings in Rhythm Pharmaceuticals, Inc. $RYTM

September 3 at 5:03 AM | marketbeat.com

Braidwell LP Acquires 70,500 Shares of Rhythm Pharmaceuticals, Inc. $RYTM

September 3 at 4:23 AM | marketbeat.com

Rhythm Pharmaceuticals stock edges lower after insider sale but stays backed by strong Q2 growth

September 2 at 7:33 PM | ad-hoc-news.deA

Rhythm Pharmaceuticals (NASDAQ:RYTM) CFO Sells $6,620,146.04 in Stock

September 2 at 5:07 AM | insidertrades.com

Hunter Smith Sells 62,774 Shares of Rhythm Pharmaceuticals (NASDAQ:RYTM) Stock

September 1 at 5:06 PM | marketbeat.com

The Manufacturers Life Insurance Company Makes New $6.35 Million Investment in Rhythm Pharmaceuticals, Inc. $RYTM

August 31 at 4:56 AM | marketbeat.com

47,400 Shares in Rhythm Pharmaceuticals, Inc. $RYTM Bought by Canada Pension Plan Investment Board

August 31 at 3:43 AM | marketbeat.com

Man Group plc Takes $5.64 Million Position in Rhythm Pharmaceuticals, Inc. $RYTM

August 30, 2026 | marketbeat.com

Bank of New York Mellon Corp Purchases Shares of 394,044 Rhythm Pharmaceuticals, Inc. $RYTM

August 28, 2026 | marketbeat.com

Jupiter Topco LLC Acquires Shares of 925,490 Rhythm Pharmaceuticals, Inc. $RYTM

August 27, 2026 | marketbeat.com

EFG International AG Invests $3.73 Million in Rhythm Pharmaceuticals, Inc. $RYTM

August 27, 2026 | marketbeat.com

Primecap Management Co. CA Invests $351.84 Million in Rhythm Pharmaceuticals, Inc. $RYTM

August 26, 2026 | marketbeat.com

Connor Clark & Lunn Investment Management Ltd. Acquires New Stake in Rhythm Pharmaceuticals, Inc. $RYTM

August 26, 2026 | marketbeat.com

Algert Global LLC Grows Position in Rhythm Pharmaceuticals, Inc. $RYTM

August 26, 2026 | marketbeat.com

ADAR1 Capital Management LLC Makes New Investment in Rhythm Pharmaceuticals, Inc. $RYTM

August 26, 2026 | marketbeat.com

Nicholas Investment Partners LP Makes New $15.46 Million Investment in Rhythm Pharmaceuticals, Inc. $RYTM

August 25, 2026 | marketbeat.com

Nan Fung Group Holdings Ltd Purchases New Position in Rhythm Pharmaceuticals, Inc. $RYTM

August 25, 2026 | marketbeat.com

Rhythm Pharmaceuticals Receives Japan Approval for Imcivree

August 24, 2026 | finance.yahoo.com

Rhythm Pharmaceuticals Announces MHLW Approval of IMCIVREE® (setmelanotide) for Patients with Acquired Hypothalamic Obesity (HO) in Japan

August 24, 2026 | globenewswire.com

6,156,902 Shares in Rhythm Pharmaceuticals, Inc. $RYTM Purchased by BlackRock Inc.

August 24, 2026 | marketbeat.com

Eli Lilly and Novo Nordisk Can't Treat This Form of Obesity. Billionaire Stanley Druckenmiller Is Betting Rhythm Pharmaceuticals Can

August 23, 2026 | fool.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

RYTM, INSM, BNTX, and INCY Company Descriptions

BioNTech NASDAQ:BNTX

$102.88 -0.93 (-0.90%)

As of 04:00 PM Eastern

BioNTech SE, a biotechnology company, develops and commercializes immunotherapies for cancer and other infectious diseases. The company is developing FixVac product candidates, including BNT111, which is in Phase II clinical trial for advance melanoma; BNT112 that is in Phase I/IIa clinical trial for prostate cancer; BNT113, which is in Phase II clinical trial to treat HPV 16+ head and neck cancers; BNT114 to treat triple negative breast cancer; BNT115, which is in Phase I clinical trial in ovarian cancer; and BNT116, which is in Phase I clinical trial for non-small cell lung cancer. It develops BNT122, which is in Phase II clinical trial for first-line melanoma and in Phase I clinical trial to treat multiple solid tumors; BNT131 that is in Phase I clinical trial for multiple solid tumors; BNT141 and BNT142 that are in Phase I clinical trial to treat multiple solid tumors; BNT151, BNT152, and BNT153 to treat solid tumors; BNT211 to treat multiple solid tumors, and BNT221 for pancreatic and other cancers; BNT311 which are in Phase II clinical trial to treat metastatic non-small cell lung cancer and Phase I/II clinical trial to treat multiple solid tumors; and BNT312, which is in Phase 2 clinical trial to treat multiple solid tumors, as well as ONC-392, which is in Phase III clinical trial to treat ovarian cancer and Phase I/II clinical trial to treat multiple solid tumors. It develops BNT321, an IgG1 monoclonal antibody in Phase I clinical trial for pancreatic cancer; BNT411, a small molecule immunomodulator product candidate in Phase I clinical trial for solid tumors; BNT322, which is in Phase I/Ib clinical trial for multiple solid tumors; and prophylactic vaccine for shingles, malaria, tuberculosis, HSV-2, and other infectious diseases. It has collaborations with Genentech, Inc.; Sanofi S.A.; Genmab A/S; Pfizer Inc.; Shanghai Fosun Pharmaceutical (Group) Co., Ltd; and Ryvu Therapeutics S.A. BioNTech SE was incorporated in 2008 and is based in Mainz, Germany.

Incyte NASDAQ:INCY

$128.00 -0.83 (-0.64%)

As of 04:00 PM Eastern

Incyte Corporation, a biopharmaceutical company, engages in the discovery, development, and commercialization of therapeutics for hematology/oncology, and inflammation and autoimmunity areas in the United States and internationally. The company offers JAKAFI (ruxolitinib) for treatment of intermediate or high-risk myelofibrosis, polycythemia vera, and steroid-refractory acute graft-versus-host disease; MONJUVI (tafasitamab-cxix)/MINJUVI (tafasitamab) for relapsed or refractory diffuse large B-cell lymphoma; PEMAZYRE (pemigatinib), a fibroblast growth factor receptor kinase inhibitor that act as oncogenic drivers in liquid and solid tumor types; ICLUSIG (ponatinib) to treat chronic myeloid leukemia and Philadelphia-chromosome positive acute lymphoblastic leukemia; and ZYNYZ (retifanlimab-dlwr) to treat adults with metastatic or recurrent locally advanced Merkel cell carcinoma, as well as OPZELURA cream for treatment of atopic dermatitis. Its clinical stage products include retifanlimab under Phase 3 clinical trials for squamous cell carcinoma of the anal canal and non-small cell lung cancer; axatilimab, an anti-CSF-1R monoclonal antibody under Phase 2 that is being developed as a therapy for patients with chronic GVHD; INCA033989 to inhibit oncogenesis; INCB160058, which is being developed as a disease-modifying therapeutic; and INCB99280 and INCB99318 for the treatment solid tumors. The company also develops INCB123667, INCA32459, and INCA33890, as well as Ruxolitinib cream, Povorcitinib, and INCA034460. It has collaboration out-license agreements with Novartis and Lilly; in-license agreements with Agenus, Merus, MacroGenics, and Syndax; and collaboration and license agreement with China Medical System Holdings Limited for the development and commercialization of povorcitinib. The company sells its products to specialty, retail, and hospital pharmacies, distributors, and wholesalers. The company was formerly known as Incyte Genomics Inc and changed its name to Incyte Corporation in March 2003. Incyte Corporation was incorporated in 1991 and is headquartered in Wilmington, Delaware.

Insmed NASDAQ:INSM

$126.68 +0.05 (+0.04%)

As of 04:00 PM Eastern

Insmed Incorporated is a global biopharmaceutical company on a mission to transform the lives of patients with serious and rare diseases. Insmed's first commercial product is ARIKAYCE® (amikacin liposome inhalation suspension), which is approved in the United States for the treatment of Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. MAC lung disease is a rare and often chronic infection that can cause irreversible lung damage and can be fatal. Insmed's earlier-stage clinical pipeline includes INS1007, a novel oral reversible inhibitor of dipeptidyl peptidase 1 with therapeutic potential in non-cystic fibrosis bronchiectasis and other inflammatory diseases, and INS1009, an inhaled formulation of a treprostinil prodrug that may offer a differentiated product profile for rare pulmonary disorders, including pulmonary arterial hypertension.

Rhythm Pharmaceuticals NASDAQ:RYTM

$104.89 -0.53 (-0.50%)

As of 04:00 PM Eastern

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases. The company's lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, and Bardet-Biedl and Alström syndrome. It is in Phase 3 clinical trials for treating POMC or LEPR heterozygous deficiency obesities, steroid receptor coactivator 1 deficiency obesity, SH2B1 deficiency obesity, MC4 receptor deficiency obesity, and other MC4R disorders. The company has licensing agreements with LG Chem, Ltd; Ipsen Pharma S.A.S; Camurus; RareStone Group Ltd.; and LG Chem, Ltd. The company was formerly known as Rhythm Metabolic, Inc. and changed its name to Rhythm Pharmaceuticals, Inc. in October 2015. Rhythm Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Boston, Massachusetts.

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Compare Stocks

Comparative Price Performance Over Time

Compare Price & Volume

Compare Price Performance

Compare Price & Volume

Compare Price Performance

Compare Analyst Forecasts

Current Analyst Ratings Breakdown

Latest RYTM, INSM, BNTX, and INCY Analyst Ratings

Compare Sales & Book Value

Compare Profitability & Earnings

Latest RYTM, INSM, BNTX, and INCY Earnings

Compare Dividends

Compare Debt

Compare Ownership

Institutional Ownership

Insider Ownership

Compare Miscellaneous Stats

RYTM, INSM, BNTX, and INCY Headlines

Recent News About These Companies

New MarketBeat Followers Over Time

Media Sentiment Over Time

RYTM, INSM, BNTX, and INCY Company Descriptions

BioNTech NASDAQ:BNTX

Incyte NASDAQ:INCY

Insmed NASDAQ:INSM

Rhythm Pharmaceuticals NASDAQ:RYTM

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Current Analyst Ratings Breakdown

Latest RYTM, INSM, BNTX, and INCY Analyst Ratings

Compare Sales & Book Value

Compare Profitability & Earnings

Latest RYTM, INSM, BNTX, and INCY Earnings

Compare Dividends

Compare Debt

Compare Ownership

Institutional Ownership

Insider Ownership

Compare Miscellaneous Stats

RYTM, INSM, BNTX, and INCY Headlines

Recent News About These Companies

New MarketBeat Followers Over Time

Media Sentiment Over Time

RYTM, INSM, BNTX, and INCY Company Descriptions

BioNTech NASDAQ:BNTX

Incyte NASDAQ:INCY

Insmed NASDAQ:INSM

Rhythm Pharmaceuticals NASDAQ:RYTM

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