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Aclaris Therapeutics (ACRS) Competitors

Aclaris Therapeutics logo
$5.50 +0.10 (+1.85%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$5.38 -0.12 (-2.11%)
As of 09/18/2026 07:30 PM Eastern
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ACRS vs. RCUS, QURE, CLDX, GMTX, and ZLAB

Should you buy Aclaris Therapeutics stock or one of its competitors? Aclaris Therapeutics's main competitors and comparable companies include Arcus Biosciences (RCUS), uniQure (QURE), Celldex Therapeutics (CLDX), Gemini Therapeutics (GMTX), and Zai Lab (ZLAB). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Aclaris Therapeutics compare to Arcus Biosciences?

Aclaris Therapeutics (NASDAQ:ACRS) and Arcus Biosciences (NYSE:RCUS) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their earnings, institutional ownership, valuation, risk, media sentiment, dividends, profitability and analyst recommendations.

Arcus Biosciences has a net margin of -393.16% compared to Aclaris Therapeutics' net margin of -921.50%. Aclaris Therapeutics' return on equity of -61.65% beat Arcus Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Aclaris Therapeutics-921.50% -61.65% -42.41%
Arcus Biosciences -393.16%-89.54%-45.61%

Aclaris Therapeutics has higher earnings, but lower revenue than Arcus Biosciences. Aclaris Therapeutics is trading at a lower price-to-earnings ratio than Arcus Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aclaris Therapeutics$7.83M98.21-$64.92M-$0.58N/A
Arcus Biosciences$247M13.04-$353M-$3.90N/A

Aclaris Therapeutics has a beta of 0.79, meaning that its stock price is 21% less volatile than the broader market. Comparatively, Arcus Biosciences has a beta of 0.81, meaning that its stock price is 19% less volatile than the broader market.

In the previous week, Arcus Biosciences had 2 more articles in the media than Aclaris Therapeutics. MarketBeat recorded 4 mentions for Arcus Biosciences and 2 mentions for Aclaris Therapeutics. Aclaris Therapeutics' average media sentiment score of 0.50 beat Arcus Biosciences' score of 0.34 indicating that Aclaris Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aclaris Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Arcus Biosciences
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Aclaris Therapeutics currently has a consensus target price of $11.33, suggesting a potential upside of 106.06%. Arcus Biosciences has a consensus target price of $38.30, suggesting a potential upside of 51.40%. Given Aclaris Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Aclaris Therapeutics is more favorable than Arcus Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aclaris Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
3 Strong Buy rating(s)
3.11
Arcus Biosciences
1 Sell rating(s)
3 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.64

98.3% of Aclaris Therapeutics shares are held by institutional investors. Comparatively, 92.9% of Arcus Biosciences shares are held by institutional investors. 4.8% of Aclaris Therapeutics shares are held by company insiders. Comparatively, 7.6% of Arcus Biosciences shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

Aclaris Therapeutics beats Arcus Biosciences on 10 of the 17 factors compared between the two stocks.

How does Aclaris Therapeutics compare to uniQure?

Aclaris Therapeutics (NASDAQ:ACRS) and uniQure (NASDAQ:QURE) are both healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their dividends, analyst recommendations, profitability, risk, earnings, media sentiment, valuation and institutional ownership.

In the previous week, Aclaris Therapeutics had 1 more articles in the media than uniQure. MarketBeat recorded 2 mentions for Aclaris Therapeutics and 1 mentions for uniQure. uniQure's average media sentiment score of 1.56 beat Aclaris Therapeutics' score of 0.50 indicating that uniQure is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aclaris Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
uniQure
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

98.3% of Aclaris Therapeutics shares are held by institutional investors. Comparatively, 78.8% of uniQure shares are held by institutional investors. 4.8% of Aclaris Therapeutics shares are held by company insiders. Comparatively, 4.7% of uniQure shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Aclaris Therapeutics has higher earnings, but lower revenue than uniQure. uniQure is trading at a lower price-to-earnings ratio than Aclaris Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aclaris Therapeutics$7.83M98.21-$64.92M-$0.58N/A
uniQure$18.67M163.46-$198.97M-$4.01N/A

Aclaris Therapeutics has a beta of 0.79, indicating that its share price is 21% less volatile than the broader market. Comparatively, uniQure has a beta of 0.94, indicating that its share price is 6% less volatile than the broader market.

Aclaris Therapeutics currently has a consensus price target of $11.33, suggesting a potential upside of 106.06%. uniQure has a consensus price target of $65.00, suggesting a potential upside of 47.73%. Given Aclaris Therapeutics' stronger consensus rating and higher probable upside, equities analysts clearly believe Aclaris Therapeutics is more favorable than uniQure.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aclaris Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
3 Strong Buy rating(s)
3.11
uniQure
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.76

Aclaris Therapeutics has a net margin of -921.50% compared to uniQure's net margin of -1,350.73%. Aclaris Therapeutics' return on equity of -61.65% beat uniQure's return on equity.

Company Net Margins Return on Equity Return on Assets
Aclaris Therapeutics-921.50% -61.65% -42.41%
uniQure -1,350.73%-111.96%-29.01%

Summary

Aclaris Therapeutics beats uniQure on 11 of the 17 factors compared between the two stocks.

How does Aclaris Therapeutics compare to Celldex Therapeutics?

Aclaris Therapeutics (NASDAQ:ACRS) and Celldex Therapeutics (NASDAQ:CLDX) are both healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, profitability, analyst recommendations, risk, valuation, institutional ownership, earnings and media sentiment.

Celldex Therapeutics has a net margin of 0.00% compared to Aclaris Therapeutics' net margin of -921.50%. Celldex Therapeutics' return on equity of -52.35% beat Aclaris Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aclaris Therapeutics-921.50% -61.65% -42.41%
Celldex Therapeutics N/A -52.35%-47.61%

Aclaris Therapeutics currently has a consensus target price of $11.33, indicating a potential upside of 106.06%. Celldex Therapeutics has a consensus target price of $56.42, indicating a potential upside of 47.53%. Given Aclaris Therapeutics' stronger consensus rating and higher possible upside, research analysts plainly believe Aclaris Therapeutics is more favorable than Celldex Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aclaris Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
3 Strong Buy rating(s)
3.11
Celldex Therapeutics
1 Sell rating(s)
1 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.85

In the previous week, Celldex Therapeutics had 3 more articles in the media than Aclaris Therapeutics. MarketBeat recorded 5 mentions for Celldex Therapeutics and 2 mentions for Aclaris Therapeutics. Celldex Therapeutics' average media sentiment score of 0.76 beat Aclaris Therapeutics' score of 0.50 indicating that Celldex Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aclaris Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Celldex Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Aclaris Therapeutics has a beta of 0.79, meaning that its stock price is 21% less volatile than the broader market. Comparatively, Celldex Therapeutics has a beta of 0.84, meaning that its stock price is 16% less volatile than the broader market.

Aclaris Therapeutics has higher revenue and earnings than Celldex Therapeutics. Aclaris Therapeutics is trading at a lower price-to-earnings ratio than Celldex Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aclaris Therapeutics$7.83M98.21-$64.92M-$0.58N/A
Celldex Therapeutics$1.54M1,949.99-$258.76M-$4.35N/A

98.3% of Aclaris Therapeutics shares are held by institutional investors. 4.8% of Aclaris Therapeutics shares are held by insiders. Comparatively, 5.2% of Celldex Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Summary

Celldex Therapeutics beats Aclaris Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Aclaris Therapeutics compare to Gemini Therapeutics?

Gemini Therapeutics (NASDAQ:GMTX) and Aclaris Therapeutics (NASDAQ:ACRS) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their valuation, risk, earnings, dividends, media sentiment, analyst recommendations, institutional ownership and profitability.

Aclaris Therapeutics has a consensus price target of $11.33, indicating a potential upside of 106.06%. Given Aclaris Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Aclaris Therapeutics is more favorable than Gemini Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Gemini Therapeutics
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00
Aclaris Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
3 Strong Buy rating(s)
3.11

75.4% of Gemini Therapeutics shares are held by institutional investors. Comparatively, 98.3% of Aclaris Therapeutics shares are held by institutional investors. 12.9% of Gemini Therapeutics shares are held by company insiders. Comparatively, 4.8% of Aclaris Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Gemini Therapeutics has a beta of -0.12, meaning that its share price is 112% less volatile than the broader market. Comparatively, Aclaris Therapeutics has a beta of 0.79, meaning that its share price is 21% less volatile than the broader market.

In the previous week, Aclaris Therapeutics had 2 more articles in the media than Gemini Therapeutics. MarketBeat recorded 2 mentions for Aclaris Therapeutics and 0 mentions for Gemini Therapeutics. Aclaris Therapeutics' average media sentiment score of 0.50 beat Gemini Therapeutics' score of 0.00 indicating that Aclaris Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Gemini Therapeutics Neutral
Aclaris Therapeutics Positive

Gemini Therapeutics has a net margin of 0.00% compared to Aclaris Therapeutics' net margin of -921.50%. Gemini Therapeutics' return on equity of -38.78% beat Aclaris Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Gemini TherapeuticsN/A -38.78% -35.88%
Aclaris Therapeutics -921.50%-61.65%-42.41%

Aclaris Therapeutics has higher revenue and earnings than Gemini Therapeutics. Gemini Therapeutics is trading at a lower price-to-earnings ratio than Aclaris Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Gemini TherapeuticsN/AN/A-$71.87M-$1.00N/A
Aclaris Therapeutics$7.83M98.21-$64.92M-$0.58N/A

Summary

Aclaris Therapeutics beats Gemini Therapeutics on 12 of the 16 factors compared between the two stocks.

How does Aclaris Therapeutics compare to Zai Lab?

Zai Lab (NASDAQ:ZLAB) and Aclaris Therapeutics (NASDAQ:ACRS) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, profitability, valuation, institutional ownership, risk, dividends, earnings and analyst recommendations.

Aclaris Therapeutics has lower revenue, but higher earnings than Zai Lab. Zai Lab is trading at a lower price-to-earnings ratio than Aclaris Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zai Lab$460.16M6.35-$175.54M-$1.71N/A
Aclaris Therapeutics$7.83M98.21-$64.92M-$0.58N/A

Zai Lab has a beta of 0.83, meaning that its share price is 17% less volatile than the broader market. Comparatively, Aclaris Therapeutics has a beta of 0.79, meaning that its share price is 21% less volatile than the broader market.

Zai Lab currently has a consensus price target of $37.25, indicating a potential upside of 44.94%. Aclaris Therapeutics has a consensus price target of $11.33, indicating a potential upside of 106.06%. Given Aclaris Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Aclaris Therapeutics is more favorable than Zai Lab.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71
Aclaris Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
3 Strong Buy rating(s)
3.11

In the previous week, Aclaris Therapeutics had 2 more articles in the media than Zai Lab. MarketBeat recorded 2 mentions for Aclaris Therapeutics and 0 mentions for Zai Lab. Aclaris Therapeutics' average media sentiment score of 0.50 beat Zai Lab's score of -0.45 indicating that Aclaris Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Zai Lab Neutral
Aclaris Therapeutics Positive

Zai Lab has a net margin of -41.86% compared to Aclaris Therapeutics' net margin of -921.50%. Zai Lab's return on equity of -27.43% beat Aclaris Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Zai Lab-41.86% -27.43% -16.72%
Aclaris Therapeutics -921.50%-61.65%-42.41%

41.7% of Zai Lab shares are held by institutional investors. Comparatively, 98.3% of Aclaris Therapeutics shares are held by institutional investors. 4.9% of Zai Lab shares are held by company insiders. Comparatively, 4.8% of Aclaris Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Summary

Aclaris Therapeutics beats Zai Lab on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ACRS and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ACRS vs. The Competition

MetricAclaris TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$755.05M$3.92B$7.26B$13.14B
Dividend YieldN/A3.65%2.57%12.30%
P/E Ratio-9.4814.30275.7925.40
Price / Sales98.211,415.50695.58114.47
Price / CashN/A110.7577.4251.66
Price / Book6.4715.4510.466.33
Net Income-$64.92M-$22.86M$3.49B$358.33M
7 Day Performance3.38%-1.21%0.59%1.12%
1 Month Performance-14.60%-4.42%-2.01%-2.67%
1 Year Performance187.96%37.81%18.09%6.01%

Aclaris Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ACRS
Aclaris Therapeutics
2.1632 of 5 stars
$5.50
+1.9%
$11.33
+106.1%
+182.1%$755.05M$7.83MN/A73
RCUS
Arcus Biosciences
3.1714 of 5 stars
$24.04
-2.2%
$38.30
+59.3%
+102.9%$3.13B$117MN/A601
QURE
uniQure
3.6917 of 5 stars
$44.93
+0.9%
$65.00
+44.7%
+198.5%$3.12B$16.10MN/A221
CLDX
Celldex Therapeutics
2.1225 of 5 stars
$39.18
+6.2%
$56.42
+44.0%
+47.5%$3.08B$1.54MN/A198
GMTX
Gemini Therapeutics
N/A$70.06
-5.5%
N/A+13.3%$3.04BN/AN/A30

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This page (NASDAQ:ACRS) was last updated on 9/19/2026 by MarketBeat.com Staff.
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