Exelixis (EXEL) Competitors $44.36 -0.33 (-0.74%) As of 05/20/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock EXEL vs. ALNY, BIIB, UTHR, NBIX, INCY, BMRN, EXAS, HALO, RGEN, and MDGLShould you be buying Exelixis stock or one of its competitors? The main competitors of Exelixis include Alnylam Pharmaceuticals (ALNY), Biogen (BIIB), United Therapeutics (UTHR), Neurocrine Biosciences (NBIX), Incyte (INCY), BioMarin Pharmaceutical (BMRN), Exact Sciences (EXAS), Halozyme Therapeutics (HALO), Repligen (RGEN), and Madrigal Pharmaceuticals (MDGL). These companies are all part of the "biotechnology" industry. Exelixis vs. Alnylam Pharmaceuticals Biogen United Therapeutics Neurocrine Biosciences Incyte BioMarin Pharmaceutical Exact Sciences Halozyme Therapeutics Repligen Madrigal Pharmaceuticals Alnylam Pharmaceuticals (NASDAQ:ALNY) and Exelixis (NASDAQ:EXEL) are both large-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their analyst recommendations, valuation, community ranking, media sentiment, profitability, risk, dividends, earnings and institutional ownership. Which has more risk and volatility, ALNY or EXEL? Alnylam Pharmaceuticals has a beta of 0.17, suggesting that its stock price is 83% less volatile than the S&P 500. Comparatively, Exelixis has a beta of 0.25, suggesting that its stock price is 75% less volatile than the S&P 500. Which has preferable earnings & valuation, ALNY or EXEL? Exelixis has lower revenue, but higher earnings than Alnylam Pharmaceuticals. Alnylam Pharmaceuticals is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAlnylam Pharmaceuticals$2.35B16.20-$278.16M-$2.09-139.56Exelixis$2.30B5.26$521.27M$2.2020.16 Do institutionals & insiders hold more shares of ALNY or EXEL? 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. Comparatively, 85.3% of Exelixis shares are held by institutional investors. 1.5% of Alnylam Pharmaceuticals shares are held by company insiders. Comparatively, 2.8% of Exelixis shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term. Does the media favor ALNY or EXEL? In the previous week, Exelixis had 30 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 50 mentions for Exelixis and 20 mentions for Alnylam Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 1.34 beat Exelixis' score of 0.75 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Alnylam Pharmaceuticals 14 Very Positive mention(s) 2 Positive mention(s) 4 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Exelixis 24 Very Positive mention(s) 4 Positive mention(s) 10 Neutral mention(s) 1 Negative mention(s) 0 Very Negative mention(s) Positive Does the MarketBeat Community favor ALNY or EXEL? Alnylam Pharmaceuticals received 540 more outperform votes than Exelixis when rated by MarketBeat users. Likewise, 76.32% of users gave Alnylam Pharmaceuticals an outperform vote while only 68.60% of users gave Exelixis an outperform vote. CompanyUnderperformOutperformAlnylam PharmaceuticalsOutperform Votes116776.32% Underperform Votes36223.68% ExelixisOutperform Votes62768.60% Underperform Votes28731.40% Is ALNY or EXEL more profitable? Exelixis has a net margin of 24.04% compared to Alnylam Pharmaceuticals' net margin of -12.37%. Exelixis' return on equity of 23.52% beat Alnylam Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Alnylam Pharmaceuticals-12.37% N/A -6.83% Exelixis 24.04%23.52%17.95% Do analysts prefer ALNY or EXEL? Alnylam Pharmaceuticals currently has a consensus price target of $319.17, suggesting a potential upside of 9.42%. Exelixis has a consensus price target of $38.94, suggesting a potential downside of 12.22%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Exelixis.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Alnylam Pharmaceuticals 1 Sell rating(s) 4 Hold rating(s) 21 Buy rating(s) 0 Strong Buy rating(s) 2.77Exelixis 2 Sell rating(s) 6 Hold rating(s) 11 Buy rating(s) 0 Strong Buy rating(s) 2.47 SummaryAlnylam Pharmaceuticals and Exelixis tied by winning 9 of the 18 factors compared between the two stocks. Get Exelixis News Delivered to You Automatically Sign up to receive the latest news and ratings for EXEL and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart EXEL vs. The Competition Export to ExcelMetricExelixisBiological Products IndustryMedical SectorNASDAQ ExchangeMarket Cap$12.10B$2.97B$5.42B$8.48BDividend YieldN/A1.72%5.22%4.11%P/E Ratio25.0631.5826.8020.05Price / Sales5.26414.63393.93116.47Price / Cash18.22168.6838.2534.62Price / Book5.533.376.864.61Net Income$521.27M-$72.17M$3.22B$248.19M7 Day Performance-0.65%18.10%6.81%2.97%1 Month Performance24.64%20.85%13.72%16.58%1 Year Performance111.04%-24.45%18.24%8.16% Exelixis Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)EXELExelixis4.2648 of 5 stars$44.36-0.7%$38.94-12.2%+110.6%$12.10B$2.30B25.061,220Positive NewsALNYAlnylam Pharmaceuticals3.7096 of 5 stars$270.19+7.6%$319.17+18.1%+94.1%$35.23B$2.35B-124.512,000Positive NewsBIIBBiogen4.9168 of 5 stars$124.40+5.3%$191.30+53.8%-43.6%$18.23B$9.82B11.128,720Analyst RevisionUTHRUnited Therapeutics4.9819 of 5 stars$310.80+3.1%$392.00+26.1%+12.7%$14.02B$2.99B13.65980NBIXNeurocrine Biosciences4.9305 of 5 stars$120.43+4.1%$162.00+34.5%-13.2%$11.92B$2.41B36.601,200Positive NewsINCYIncyte4.8942 of 5 stars$60.85+3.2%$73.53+20.8%+14.2%$11.78B$4.41B225.382,320Positive NewsBMRNBioMarin Pharmaceutical4.9841 of 5 stars$61.37+4.3%$93.45+52.3%-22.2%$11.77B$2.95B27.903,080Positive NewsInsider TradeGap UpEXASExact Sciences4.3503 of 5 stars$53.40+3.4%$70.90+32.8%+13.4%$10.07B$2.83B-9.596,400Positive NewsHALOHalozyme Therapeutics4.8745 of 5 stars$66.58+1.1%$63.78-4.2%+18.9%$8.20B$1.08B19.41390Gap UpRGENRepligen4.8489 of 5 stars$133.72+8.5%$173.25+29.6%-25.7%$7.51B$650.43M-262.202,020Positive NewsGap UpMDGLMadrigal Pharmaceuticals4.5838 of 5 stars$300.76+2.1%$416.33+38.4%+26.1%$6.68B$317.38M-11.9990Positive News Related Companies and Tools Related Companies Alnylam Pharmaceuticals Alternatives Biogen Alternatives United Therapeutics Alternatives Neurocrine Biosciences Alternatives Incyte Alternatives BioMarin Pharmaceutical Alternatives Exact Sciences Alternatives Halozyme Therapeutics Alternatives Repligen Alternatives Madrigal Pharmaceuticals Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:EXEL) was last updated on 5/21/2025 by MarketBeat.com Staff From Our PartnersMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredGold Hits New Highs as Global Markets SpiralWhen Trump took office in 2017, gold was just $1,100 an ounce. 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