Jade Biosciences (JBIO) Competitors $9.90 +0.75 (+8.20%) As of 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock JBIO vs. TRVI, PHVS, SYRE, DNTH, PRAX, LENZ, AMPH, UPB, RLAY, and SPRYShould you be buying Jade Biosciences stock or one of its competitors? The main competitors of Jade Biosciences include Trevi Therapeutics (TRVI), Pharvaris (PHVS), Spyre Therapeutics (SYRE), Dianthus Therapeutics (DNTH), Praxis Precision Medicines (PRAX), LENZ Therapeutics (LENZ), Amphastar Pharmaceuticals (AMPH), Upstream Bio (UPB), Relay Therapeutics (RLAY), and ARS Pharmaceuticals (SPRY). These companies are all part of the "pharmaceutical products" industry. Jade Biosciences vs. Its Competitors Trevi Therapeutics Pharvaris Spyre Therapeutics Dianthus Therapeutics Praxis Precision Medicines LENZ Therapeutics Amphastar Pharmaceuticals Upstream Bio Relay Therapeutics ARS Pharmaceuticals Jade Biosciences (NASDAQ:JBIO) and Trevi Therapeutics (NASDAQ:TRVI) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their analyst recommendations, profitability, media sentiment, dividends, risk, valuation, earnings and institutional ownership. Do insiders & institutionals hold more shares of JBIO or TRVI? 95.8% of Trevi Therapeutics shares are held by institutional investors. 24.9% of Jade Biosciences shares are held by insiders. Comparatively, 18.3% of Trevi Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth. Do analysts prefer JBIO or TRVI? Jade Biosciences presently has a consensus target price of $19.00, suggesting a potential upside of 91.92%. Trevi Therapeutics has a consensus target price of $21.75, suggesting a potential upside of 104.80%. Given Trevi Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Trevi Therapeutics is more favorable than Jade Biosciences.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Jade Biosciences 1 Sell rating(s) 0 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 2.60Trevi Therapeutics 1 Sell rating(s) 0 Hold rating(s) 7 Buy rating(s) 1 Strong Buy rating(s) 2.89 Is JBIO or TRVI more profitable? Trevi Therapeutics' return on equity of -41.44% beat Jade Biosciences' return on equity.Company Net Margins Return on Equity Return on Assets Jade BiosciencesN/A -51.96% -47.65% Trevi Therapeutics N/A -41.44%-38.21% Does the media refer more to JBIO or TRVI? In the previous week, Jade Biosciences had 12 more articles in the media than Trevi Therapeutics. MarketBeat recorded 18 mentions for Jade Biosciences and 6 mentions for Trevi Therapeutics. Trevi Therapeutics' average media sentiment score of 0.54 beat Jade Biosciences' score of 0.43 indicating that Trevi Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Jade Biosciences 2 Very Positive mention(s) 2 Positive mention(s) 2 Neutral mention(s) 1 Negative mention(s) 0 Very Negative mention(s) Neutral Trevi Therapeutics 1 Very Positive mention(s) 2 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has more risk and volatility, JBIO or TRVI? Jade Biosciences has a beta of 1.05, indicating that its stock price is 5% more volatile than the S&P 500. Comparatively, Trevi Therapeutics has a beta of 0.74, indicating that its stock price is 26% less volatile than the S&P 500. Which has higher earnings and valuation, JBIO or TRVI? Trevi Therapeutics is trading at a lower price-to-earnings ratio than Jade Biosciences, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioJade BiosciencesN/AN/A-$69.63M-$30.33-0.33Trevi TherapeuticsN/AN/A-$47.91M-$0.42-25.29 SummaryTrevi Therapeutics beats Jade Biosciences on 10 of the 14 factors compared between the two stocks. Get Jade Biosciences News Delivered to You Automatically Sign up to receive the latest news and ratings for JBIO and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding JBIO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart JBIO vs. The Competition Export to ExcelMetricJade BiosciencesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$298.54M$3.38B$6.11B$10.47BDividend YieldN/A2.29%5.73%4.77%P/E Ratio-0.3322.7785.3627.36Price / SalesN/A483.07607.44135.43Price / CashN/A46.7037.4661.86Price / Book0.1110.5512.426.81Net Income-$69.63M-$52.58M$3.32B$276.80M7 Day Performance9.03%1.09%1.01%0.27%1 Month Performance40.03%16.09%10.75%8.31%1 Year PerformanceN/A18.41%76.20%35.60% Jade Biosciences Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)JBIOJade Biosciences2.5247 of 5 stars$9.90+8.2%$19.00+91.9%N/A$298.54MN/A-0.3320TRVITrevi Therapeutics2.5758 of 5 stars$10.19+4.9%$21.75+113.4%+220.4%$1.18BN/A-24.2620PHVSPharvaris2.7459 of 5 stars$20.96-5.0%$37.17+77.3%+1.9%$1.15BN/A-6.2430News CoveragePositive NewsAnalyst ForecastSYRESpyre Therapeutics3.1875 of 5 stars$21.00+11.0%$54.29+158.5%-31.5%$1.14B$890K-6.1873Trending NewsAnalyst UpgradeAnalyst RevisionGap UpHigh Trading VolumeDNTHDianthus Therapeutics3.1493 of 5 stars$35.54+3.3%$60.88+71.3%+39.8%$1.11B$6.24M-10.9480News CoverageAnalyst ForecastPRAXPraxis Precision Medicines2.0255 of 5 stars$52.52+0.3%$85.56+62.9%-25.0%$1.10B$8.55M-4.27110LENZLENZ Therapeutics1.7624 of 5 stars$38.80+0.5%$52.80+36.1%+52.2%$1.10B$5M-20.42110AMPHAmphastar Pharmaceuticals4.5656 of 5 stars$23.86+1.5%$31.60+32.4%-51.6%$1.09B$731.97M8.942,028News CoverageUPBUpstream Bio2.1402 of 5 stars$19.98-0.5%$53.33+166.9%-14.5%$1.08B$2.72M0.0038News CoverageAnalyst ForecastRLAYRelay Therapeutics2.5918 of 5 stars$6.03-3.8%$16.50+173.6%-10.7%$1.08B$10.01M-3.09330News CoverageAnalyst ForecastSPRYARS Pharmaceuticals2.982 of 5 stars$10.66-2.5%$33.80+217.1%-28.7%$1.08B$112.34M-21.7590 Related Companies and Tools Related Companies Trevi Therapeutics Competitors Pharvaris Competitors Spyre Therapeutics Competitors Dianthus Therapeutics Competitors Praxis Precision Medicines Competitors LENZ Therapeutics Competitors Amphastar Pharmaceuticals Competitors Upstream Bio Competitors Relay Therapeutics Competitors ARS Pharmaceuticals Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:JBIO) was last updated on 10/15/2025 by MarketBeat.com Staff From Our PartnersURGENT: The Market's 3 Red Flags Are FlashingHere’s the uncomfortable truth: The smartest investors in the world are already preparing for a crash befor...StockEarnings | SponsoredINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredArizona-made nanochips the new millionaire maker?George Gilder handed President Reagan the first microchip that helped create $6.5 trillion in wealth over the ...Banyan Hill Publishing | SponsoredBuy UBER immediatelyBULLISH: It's time to buy this 'hidden' AI stock An award-winning stock-rating system has turned BULLISH on...Chaikin Analytics | SponsoredFront-Run Buffett's Shocking Gold MoveA Historic Gold Announcement Is About to Rock Wall Street? 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