Jade Biosciences (JBIO) Competitors $8.06 -0.06 (-0.74%) As of 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock JBIO vs. UPB, RAPP, SYRE, ABUS, PRAX, URGN, IMNM, TSHA, IOVA, and PHATShould you be buying Jade Biosciences stock or one of its competitors? The main competitors of Jade Biosciences include Upstream Bio (UPB), Rapport Therapeutics (RAPP), Spyre Therapeutics (SYRE), Arbutus Biopharma (ABUS), Praxis Precision Medicines (PRAX), Urogen Pharma (URGN), Immunome (IMNM), Taysha Gene Therapies (TSHA), Iovance Biotherapeutics (IOVA), and Phathom Pharmaceuticals (PHAT). These companies are all part of the "pharmaceutical products" industry. Jade Biosciences vs. Its Competitors Upstream Bio Rapport Therapeutics Spyre Therapeutics Arbutus Biopharma Praxis Precision Medicines Urogen Pharma Immunome Taysha Gene Therapies Iovance Biotherapeutics Phathom Pharmaceuticals Upstream Bio (NASDAQ:UPB) and Jade Biosciences (NASDAQ:JBIO) are both small-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, valuation, profitability, earnings, analyst recommendations, media sentiment, institutional ownership and dividends. Does the media refer more to UPB or JBIO? In the previous week, Upstream Bio and Upstream Bio both had 1 articles in the media. Jade Biosciences' average media sentiment score of 1.89 beat Upstream Bio's score of 1.28 indicating that Jade Biosciences is being referred to more favorably in the news media. Company Overall Sentiment Upstream Bio Positive Jade Biosciences Very Positive Is UPB or JBIO more profitable? Jade Biosciences has a net margin of 0.00% compared to Upstream Bio's net margin of -3,836.58%. Upstream Bio's return on equity of -35.90% beat Jade Biosciences' return on equity.Company Net Margins Return on Equity Return on Assets Upstream Bio-3,836.58% -35.90% -26.26% Jade Biosciences N/A -51.96%-47.65% Which has better earnings and valuation, UPB or JBIO? Upstream Bio has higher revenue and earnings than Jade Biosciences. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioUpstream Bio$2.37M371.00-$62.81MN/AN/AJade BiosciencesN/AN/A-$69.63M-$30.33-0.27 Do analysts rate UPB or JBIO? Upstream Bio presently has a consensus price target of $56.50, suggesting a potential upside of 246.41%. Jade Biosciences has a consensus price target of $16.00, suggesting a potential upside of 98.51%. Given Upstream Bio's higher probable upside, equities research analysts plainly believe Upstream Bio is more favorable than Jade Biosciences.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Upstream Bio 0 Sell rating(s) 0 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 3.00Jade Biosciences 0 Sell rating(s) 0 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 3.00 SummaryUpstream Bio beats Jade Biosciences on 6 of the 8 factors compared between the two stocks. Get Jade Biosciences News Delivered to You Automatically Sign up to receive the latest news and ratings for JBIO and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding JBIO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart JBIO vs. The Competition Export to ExcelMetricJade BiosciencesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$263.00M$3.07B$5.65B$10.29BDividend YieldN/A2.36%5.68%4.62%P/E Ratio-0.2720.7675.8426.11Price / SalesN/A403.84517.46171.25Price / CashN/A45.9137.5661.52Price / Book0.099.6212.876.30Net Income-$69.63M-$52.73M$3.29B$271.03M7 Day Performance4.54%0.64%-0.26%-0.15%1 Month Performance2.03%6.31%3.84%6.41%1 Year PerformanceN/A18.97%68.35%28.81% Jade Biosciences Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)JBIOJade Biosciences2.4158 of 5 stars$8.06-0.7%$16.00+98.5%N/A$263.00MN/A-0.2720UPBUpstream Bio1.6188 of 5 stars$17.35+3.3%$56.50+225.6%N/A$905.14M$2.37M0.0038Positive NewsRAPPRapport Therapeutics2.8203 of 5 stars$26.19+5.9%$35.33+34.9%+26.0%$902.59MN/A-10.48N/ASYRESpyre Therapeutics2.5306 of 5 stars$14.82-0.1%$56.17+279.0%-39.6%$896.35M$890K-4.3673ABUSArbutus Biopharma2.1253 of 5 stars$4.40-2.9%$5.00+13.6%+11.7%$868.40M$6.17M-15.1790Positive NewsPRAXPraxis Precision Medicines2.1042 of 5 stars$42.00+3.8%$85.88+104.5%-17.1%$851.46M$8.55M-3.42110Gap DownURGNUrogen Pharma4.1954 of 5 stars$18.07+0.1%$32.00+77.1%+37.7%$835.53M$90.40M-5.44200Positive NewsIMNMImmunome2.1438 of 5 stars$9.09-4.1%$22.89+151.8%-23.3%$825.19M$9.04M-2.9540Analyst ForecastGap DownTSHATaysha Gene Therapies2.1533 of 5 stars$2.84-6.0%$8.29+191.8%+52.9%$823.84M$8.33M-8.35180News CoveragePositive NewsIOVAIovance Biotherapeutics4.4589 of 5 stars$2.30+1.3%$11.90+417.4%-77.3%$821.41M$164.07M-1.87500PHATPhathom Pharmaceuticals2.5128 of 5 stars$10.98-4.4%$17.50+59.4%-32.0%$814.43M$55.25M-2.32110 Related Companies and Tools Related Companies Upstream Bio Competitors Rapport Therapeutics Competitors Spyre Therapeutics Competitors Arbutus Biopharma Competitors Praxis Precision Medicines Competitors Urogen Pharma Competitors Immunome Competitors Taysha Gene Therapies Competitors Iovance Biotherapeutics Competitors Phathom Pharmaceuticals Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:JBIO) was last updated on 9/25/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredHe Called Nvidia at $1.10. 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