Free Trial

Ligand Pharmaceuticals (LGND) Competitors

Ligand Pharmaceuticals logo
$210.33 -22.22 (-9.55%)
Closing price 05/7/2026 04:00 PM Eastern
Extended Trading
$211.50 +1.16 (+0.55%)
As of 07:00 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

LGND vs. ADMA, ANIP, NBIX, IONS, and MDGL

Should you be buying Ligand Pharmaceuticals stock or one of its competitors? The main competitors of Ligand Pharmaceuticals include ADMA Biologics (ADMA), ANI Pharmaceuticals (ANIP), Neurocrine Biosciences (NBIX), Ionis Pharmaceuticals (IONS), and Madrigal Pharmaceuticals (MDGL). These companies are all part of the "medical" sector.

How does Ligand Pharmaceuticals compare to ADMA Biologics?

Ligand Pharmaceuticals (NASDAQ:LGND) and ADMA Biologics (NASDAQ:ADMA) are both mid-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their earnings, media sentiment, risk, institutional ownership, dividends, profitability, valuation and analyst recommendations.

Ligand Pharmaceuticals has a net margin of 46.42% compared to ADMA Biologics' net margin of 32.43%. ADMA Biologics' return on equity of 38.94% beat Ligand Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ligand Pharmaceuticals46.42% 13.86% 10.18%
ADMA Biologics 32.43%38.94%29.06%

Ligand Pharmaceuticals currently has a consensus price target of $256.29, suggesting a potential upside of 21.85%. ADMA Biologics has a consensus price target of $19.00, suggesting a potential upside of 124.32%. Given ADMA Biologics' higher possible upside, analysts plainly believe ADMA Biologics is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ligand Pharmaceuticals
0 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.88
ADMA Biologics
0 Sell rating(s)
3 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.40

In the previous week, ADMA Biologics had 21 more articles in the media than Ligand Pharmaceuticals. MarketBeat recorded 39 mentions for ADMA Biologics and 18 mentions for Ligand Pharmaceuticals. Ligand Pharmaceuticals' average media sentiment score of 0.53 beat ADMA Biologics' score of 0.17 indicating that Ligand Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ligand Pharmaceuticals
5 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
ADMA Biologics
9 Very Positive mention(s)
2 Positive mention(s)
19 Neutral mention(s)
6 Negative mention(s)
0 Very Negative mention(s)
Neutral

ADMA Biologics has higher revenue and earnings than Ligand Pharmaceuticals. ADMA Biologics is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ligand Pharmaceuticals$268.09M15.72$124.45M$5.8336.08
ADMA Biologics$509.86M3.96$146.93M$0.6812.46

91.3% of Ligand Pharmaceuticals shares are held by institutional investors. Comparatively, 75.7% of ADMA Biologics shares are held by institutional investors. 7.0% of Ligand Pharmaceuticals shares are held by insiders. Comparatively, 3.9% of ADMA Biologics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Ligand Pharmaceuticals has a beta of 1.2, indicating that its stock price is 20% more volatile than the S&P 500. Comparatively, ADMA Biologics has a beta of 0.83, indicating that its stock price is 17% less volatile than the S&P 500.

Summary

Ligand Pharmaceuticals beats ADMA Biologics on 10 of the 16 factors compared between the two stocks.

How does Ligand Pharmaceuticals compare to ANI Pharmaceuticals?

Ligand Pharmaceuticals (NASDAQ:LGND) and ANI Pharmaceuticals (NASDAQ:ANIP) are both medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, media sentiment, risk, valuation, institutional ownership, profitability, dividends and analyst recommendations.

91.3% of Ligand Pharmaceuticals shares are held by institutional investors. Comparatively, 76.1% of ANI Pharmaceuticals shares are held by institutional investors. 7.0% of Ligand Pharmaceuticals shares are held by company insiders. Comparatively, 8.1% of ANI Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Ligand Pharmaceuticals has a net margin of 46.42% compared to ANI Pharmaceuticals' net margin of 8.87%. ANI Pharmaceuticals' return on equity of 27.97% beat Ligand Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ligand Pharmaceuticals46.42% 13.86% 10.18%
ANI Pharmaceuticals 8.87%27.97%9.70%

Ligand Pharmaceuticals presently has a consensus price target of $256.29, suggesting a potential upside of 21.85%. ANI Pharmaceuticals has a consensus price target of $107.33, suggesting a potential upside of 27.91%. Given ANI Pharmaceuticals' higher probable upside, analysts plainly believe ANI Pharmaceuticals is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ligand Pharmaceuticals
0 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.88
ANI Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.88

In the previous week, Ligand Pharmaceuticals had 12 more articles in the media than ANI Pharmaceuticals. MarketBeat recorded 18 mentions for Ligand Pharmaceuticals and 6 mentions for ANI Pharmaceuticals. ANI Pharmaceuticals' average media sentiment score of 0.76 beat Ligand Pharmaceuticals' score of 0.53 indicating that ANI Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ligand Pharmaceuticals
5 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
ANI Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ligand Pharmaceuticals has a beta of 1.2, indicating that its share price is 20% more volatile than the S&P 500. Comparatively, ANI Pharmaceuticals has a beta of 0.46, indicating that its share price is 54% less volatile than the S&P 500.

Ligand Pharmaceuticals has higher earnings, but lower revenue than ANI Pharmaceuticals. ANI Pharmaceuticals is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ligand Pharmaceuticals$268.09M15.72$124.45M$5.8336.08
ANI Pharmaceuticals$883.37M2.13$78.34M$3.3624.97

Summary

Ligand Pharmaceuticals beats ANI Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

How does Ligand Pharmaceuticals compare to Neurocrine Biosciences?

Ligand Pharmaceuticals (NASDAQ:LGND) and Neurocrine Biosciences (NASDAQ:NBIX) are both medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, media sentiment, risk, valuation, institutional ownership, profitability, dividends and analyst recommendations.

91.3% of Ligand Pharmaceuticals shares are held by institutional investors. Comparatively, 92.6% of Neurocrine Biosciences shares are held by institutional investors. 7.0% of Ligand Pharmaceuticals shares are held by company insiders. Comparatively, 4.6% of Neurocrine Biosciences shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Ligand Pharmaceuticals has a net margin of 46.42% compared to Neurocrine Biosciences' net margin of 21.55%. Neurocrine Biosciences' return on equity of 19.79% beat Ligand Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ligand Pharmaceuticals46.42% 13.86% 10.18%
Neurocrine Biosciences 21.55%19.79%13.82%

Ligand Pharmaceuticals presently has a consensus price target of $256.29, suggesting a potential upside of 21.85%. Neurocrine Biosciences has a consensus price target of $183.75, suggesting a potential upside of 22.84%. Given Neurocrine Biosciences' higher probable upside, analysts plainly believe Neurocrine Biosciences is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ligand Pharmaceuticals
0 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.88
Neurocrine Biosciences
0 Sell rating(s)
5 Hold rating(s)
16 Buy rating(s)
1 Strong Buy rating(s)
2.82

In the previous week, Neurocrine Biosciences had 25 more articles in the media than Ligand Pharmaceuticals. MarketBeat recorded 43 mentions for Neurocrine Biosciences and 18 mentions for Ligand Pharmaceuticals. Neurocrine Biosciences' average media sentiment score of 0.69 beat Ligand Pharmaceuticals' score of 0.53 indicating that Neurocrine Biosciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ligand Pharmaceuticals
5 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Neurocrine Biosciences
13 Very Positive mention(s)
3 Positive mention(s)
18 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Ligand Pharmaceuticals has a beta of 1.2, indicating that its share price is 20% more volatile than the S&P 500. Comparatively, Neurocrine Biosciences has a beta of 0.34, indicating that its share price is 66% less volatile than the S&P 500.

Neurocrine Biosciences has higher revenue and earnings than Ligand Pharmaceuticals. Neurocrine Biosciences is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ligand Pharmaceuticals$268.09M15.72$124.45M$5.8336.08
Neurocrine Biosciences$2.86B5.26$478.60M$6.4923.05

Summary

Neurocrine Biosciences beats Ligand Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Ligand Pharmaceuticals compare to Ionis Pharmaceuticals?

Ionis Pharmaceuticals (NASDAQ:IONS) and Ligand Pharmaceuticals (NASDAQ:LGND) are both medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their valuation, risk, profitability, institutional ownership, media sentiment, dividends, earnings and analyst recommendations.

Ligand Pharmaceuticals has a net margin of 46.42% compared to Ionis Pharmaceuticals' net margin of -30.91%. Ligand Pharmaceuticals' return on equity of 13.86% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ionis Pharmaceuticals-30.91% -58.65% -10.07%
Ligand Pharmaceuticals 46.42%13.86%10.18%

Ligand Pharmaceuticals has lower revenue, but higher earnings than Ionis Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ionis Pharmaceuticals$944M13.31-$381.39M-$2.07N/A
Ligand Pharmaceuticals$268.09M15.72$124.45M$5.8336.08

93.9% of Ionis Pharmaceuticals shares are owned by institutional investors. Comparatively, 91.3% of Ligand Pharmaceuticals shares are owned by institutional investors. 2.6% of Ionis Pharmaceuticals shares are owned by insiders. Comparatively, 7.0% of Ligand Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

In the previous week, Ionis Pharmaceuticals had 2 more articles in the media than Ligand Pharmaceuticals. MarketBeat recorded 20 mentions for Ionis Pharmaceuticals and 18 mentions for Ligand Pharmaceuticals. Ionis Pharmaceuticals' average media sentiment score of 0.62 beat Ligand Pharmaceuticals' score of 0.53 indicating that Ionis Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ionis Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ligand Pharmaceuticals
5 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ionis Pharmaceuticals presently has a consensus price target of $99.35, suggesting a potential upside of 30.69%. Ligand Pharmaceuticals has a consensus price target of $256.29, suggesting a potential upside of 21.85%. Given Ionis Pharmaceuticals' higher possible upside, equities analysts plainly believe Ionis Pharmaceuticals is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ionis Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.86
Ligand Pharmaceuticals
0 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.88

Ionis Pharmaceuticals has a beta of 0.38, meaning that its share price is 62% less volatile than the S&P 500. Comparatively, Ligand Pharmaceuticals has a beta of 1.2, meaning that its share price is 20% more volatile than the S&P 500.

Summary

Ligand Pharmaceuticals beats Ionis Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Ligand Pharmaceuticals compare to Madrigal Pharmaceuticals?

Madrigal Pharmaceuticals (NASDAQ:MDGL) and Ligand Pharmaceuticals (NASDAQ:LGND) are both medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their valuation, risk, profitability, institutional ownership, media sentiment, dividends, earnings and analyst recommendations.

Ligand Pharmaceuticals has a net margin of 46.42% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Ligand Pharmaceuticals' return on equity of 13.86% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Madrigal Pharmaceuticals-27.32% -48.24% -25.52%
Ligand Pharmaceuticals 46.42%13.86%10.18%

Ligand Pharmaceuticals has lower revenue, but higher earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Madrigal Pharmaceuticals$1.13B10.88-$288.28M-$12.80N/A
Ligand Pharmaceuticals$268.09M15.72$124.45M$5.8336.08

98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. Comparatively, 91.3% of Ligand Pharmaceuticals shares are owned by institutional investors. 21.5% of Madrigal Pharmaceuticals shares are owned by insiders. Comparatively, 7.0% of Ligand Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

In the previous week, Ligand Pharmaceuticals had 2 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 18 mentions for Ligand Pharmaceuticals and 16 mentions for Madrigal Pharmaceuticals. Ligand Pharmaceuticals' average media sentiment score of 0.53 beat Madrigal Pharmaceuticals' score of 0.49 indicating that Ligand Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Madrigal Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Ligand Pharmaceuticals
5 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Madrigal Pharmaceuticals presently has a consensus price target of $682.07, suggesting a potential upside of 27.52%. Ligand Pharmaceuticals has a consensus price target of $256.29, suggesting a potential upside of 21.85%. Given Madrigal Pharmaceuticals' higher possible upside, equities analysts plainly believe Madrigal Pharmaceuticals is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.76
Ligand Pharmaceuticals
0 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.88

Madrigal Pharmaceuticals has a beta of -1.04, meaning that its share price is 204% less volatile than the S&P 500. Comparatively, Ligand Pharmaceuticals has a beta of 1.2, meaning that its share price is 20% more volatile than the S&P 500.

Summary

Ligand Pharmaceuticals beats Madrigal Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

Get Ligand Pharmaceuticals News Delivered to You Automatically

Sign up to receive the latest news and ratings for LGND and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding LGND and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

LGND vs. The Competition

MetricLigand PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$4.66B$3.44B$6.30B$12.14B
Dividend YieldN/A2.22%2.78%5.24%
P/E Ratio36.0833.4528.4527.00
Price / Sales15.72294.85534.7676.45
Price / Cash29.62125.2843.3053.97
Price / Book4.077.309.836.89
Net Income$124.45M$23.67M$3.55B$333.11M
7 Day PerformanceN/AN/AN/A0.14%
1 Month Performance1.08%4.95%5.22%6.78%
1 Year Performance105.18%75.81%40.39%38.93%

Ligand Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
LGND
Ligand Pharmaceuticals
4.4727 of 5 stars
$210.33
-9.6%
$256.29
+21.8%
+99.1%$4.66B$268.09M36.0880
ADMA
ADMA Biologics
4.6977 of 5 stars
$10.52
+2.6%
$25.67
+144.0%
-64.1%$2.51B$510.17M17.53530
ANIP
ANI Pharmaceuticals
4.2422 of 5 stars
$80.39
+1.2%
$107.33
+33.5%
+18.5%$1.80B$883.37M23.93600
NBIX
Neurocrine Biosciences
3.9455 of 5 stars
$131.78
+0.1%
$180.45
+36.9%
+23.1%$13.25B$2.86B28.282,000
IONS
Ionis Pharmaceuticals
3.7179 of 5 stars
$75.28
+0.7%
$99.35
+32.0%
+129.9%$12.43B$1.06BN/A1,402

Related Companies and Tools


This page (NASDAQ:LGND) was last updated on 5/8/2026 by MarketBeat.com Staff.
From Our Partners