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Lexicon Pharmaceuticals (LXRX) Institutional Ownership

Lexicon Pharmaceuticals logo
$1.78 +0.17 (+10.56%)
Closing price 11/6/2026 04:00 PM Eastern
Extended Trading
$1.79 +0.01 (+0.56%)
As of 11/6/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Lexicon Pharmaceuticals (NASDAQ:LXRX)

Current
Institutional Ownership
Percentage
74.70%
Number of
Institutional Buyers
(last 12 months)
45
Total
Institutional Inflows
(last 12 months)
$32.45M
Number of
Institutional Sellers
(last 12 months)
20
Total
Institutional Outflows
(last 12 months)
$7.76M
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LXRX Institutional Buying and Selling by Quarter

Lexicon Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/6/2026 R Squared Ltd33,845$63K0.0%-38.4%0.008%
11/3/2026 Pictet Asset Management Holding SA21,835$41K0.0%N/A0.005%
10/29/2026 Profund Advisors LLC340,479$638K0.0%+600.8%0.077%
10/29/2026 State of Wyoming15,012$28K0.0%-87.4%0.003%
10/28/2026 VIRGINIA RETIREMENT SYSTEMS ET Al35,300$66K0.0%N/A0.008%
9/9/2026WINTON GROUP Ltd43,200$104K0.0%+69.4%0.010%
9/9/2026Squarepoint Ops LLC11,741$28K0.0%N/A0.003%
8/21/2026AXQ Capital LP45,727$110K0.0%+126.9%0.010%
8/20/2026Headlands Technologies LLC167,198$401K0.0%-12.6%0.038%
8/20/2026 Wedbush Securities Inc.20,000$48K0.0%-51.0%0.004%
8/19/2026Wellington Management Group LLP179,700$431K0.0%N/A0.040%
8/6/2026 Bank of New York Mellon Corp568,706$1.37M0.0%N/A0.128%
5/21/2026CTC Alternative Strategies Ltd.17,544$27K0.1%N/A0.004%
5/19/2026Bank of America Corp DE526,103$821K0.0%+415.3%0.118%
5/18/2026ADAR1 Capital Management LLC750,000$1.17M0.1%N/A0.169%
5/15/2026OMERS ADMINISTRATION Corp106,800$167K0.0%-61.0%0.024%
5/15/2026Bridgewater Advisors Inc.82,209$128K0.0%N/A0.019%
5/14/2026Renaissance Technologies LLC1,600,500$2.50M0.0%+508.0%0.360%
5/14/2026Siren L.L.C.44,303,518$69.11M1.9%+13.8%9.974%
5/14/2026Bank of Nova Scotia73,707$115K0.0%N/A0.017%
5/5/2026 Bank of New York Mellon Corp27,459$43K0.0%+43.6%0.006%
4/29/2026 R Squared Ltd67,526$105K0.1%+45.0%0.016%
2/23/2026Virtu Financial LLC36,468$42K0.0%N/A0.010%
2/19/2026Invesco Ltd.594,883$684K0.0%+14.1%0.164%
2/18/2026XTX Topco Ltd96,090$111K0.0%-70.8%0.026%
2/18/2026Ikarian Capital LLC164,674$189K0.0%-6.7%0.045%
2/18/2026Millennium Management LLC4,821,733$5.55M0.0%+25.9%1.327%
2/18/2026Ishara Investments LP880,000$1.01M1.2%N/A0.242%
2/18/2026Boothbay Fund Management LLC44,315$51K0.0%-21.0%0.012%
2/17/2026AQR Capital Management LLC144,800$167K0.0%-52.2%0.040%
2/17/2026ExodusPoint Capital Management LP268,433$309K0.0%N/A0.074%
2/17/2026Graham Capital Management L.P.109,900$126K0.0%N/A0.030%
2/16/2026OMERS ADMINISTRATION Corp273,800$315K0.0%N/A0.075%
2/16/2026 Barclays PLC194,743$224K0.0%+511.2%0.054%
2/13/2026Security National Bank of Sioux City Iowa IA26,650$31K0.0%N/A0.007%
2/13/2026Marshall Wace LLP1,262,367$1.45M0.0%N/A0.347%
2/13/2026Hudson Bay Capital Management LP100,532$116K0.0%N/A0.028%
2/13/2026Quarry LP88,000$101K0.0%N/A0.024%
2/13/2026Headlands Technologies LLC136,113$157K0.0%+174.2%0.037%
2/13/2026Charles Schwab Investment Management Inc.1,055,123$1.21M0.0%-7.8%0.290%
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2/12/2026HRT Financial LP117,549$135K0.0%+153.1%0.032%
2/12/2026Renaissance Technologies LLC263,254$303K0.0%-10.0%0.072%
2/12/2026EntryPoint Capital LLC33,618$39K0.0%N/A0.009%
2/12/2026CIBC Private Wealth Group LLC1,950,000$2.24M0.0%-18.8%0.536%
2/11/2026Cerity Partners LLC144,944$167K0.0%-8.3%0.040%
2/11/2026 State of Wyoming60,571$70K0.0%+610.4%0.017%
2/10/2026 CIBC Asset Management Inc39,520$45K0.0%N/A0.011%
2/10/2026Goldman Sachs Group Inc.921,204$1.06M0.0%+1,452.2%0.253%
2/10/2026Monaco Asset Management SAM117,188$135K0.0%-66.5%0.032%
2/9/2026 Geode Capital Management LLC2,500,022$2.88M0.0%+4.3%0.688%
2/6/2026 Leonteq Securities AG30,000$34K0.0%N/A0.008%
2/6/2026GSA Capital Partners LLP996,235$1.15M0.1%-17.2%0.274%
2/5/2026 Pinnacle Associates Ltd.29,015$33K0.0%-42.9%0.008%
1/30/2026 R Squared Ltd46,579$54K0.0%+45.3%0.013%
1/29/2026UBS Group AG3,007,237$3.46M0.0%+752.1%0.828%
1/14/2026 Hennion & Walsh Asset Management Inc.901,222$1.04M0.0%+15.7%0.248%
11/26/2025Vermillion & White Wealth Management Group LLC32,500$44K0.0%+400.0%0.009%
11/24/2025CIBC Private Wealth Group LLC2,400,257$3.24M0.0%-2.0%0.661%
11/21/2025CIBC Bancorp USA Inc.2,400,257$3.24M0.0%N/A0.661%
11/17/2025Jacobs Levy Equity Management Inc.692,727$935K0.0%N/A0.191%
11/17/2025Scientech Research LLC24,884$34K0.0%-57.0%0.007%
11/17/2025Millennium Management LLC3,830,660$5.17M0.0%+133.1%1.054%
11/17/2025Bank of America Corp DE57,804$78K0.0%+80.1%0.016%
11/14/2025Schonfeld Strategic Advisors LLC825,633$1.12M0.0%-82.0%0.227%
11/14/2025Two Sigma Investments LP559,008$755K0.0%+38.4%0.154%
11/14/2025Squarepoint Ops LLC58,676$79K0.0%-38.6%0.016%
11/13/2025Jefferies Financial Group Inc.97,400$131K0.0%N/A0.027%
11/10/2025Optiver Holding B.V.75,893$102K0.0%+2,400.6%0.021%
11/10/2025Monaco Asset Management SAM350,000$472K0.0%-34.2%0.096%
11/10/2025 China Universal Asset Management Co. Ltd.63,698$86K0.0%-12.7%0.018%
11/7/2025GSA Capital Partners LLP1,202,906$1.62M0.1%-57.5%0.331%
11/7/2025Vanguard Group Inc.9,521,874$12.86M0.0%+7.6%2.620%
11/6/2025 Compagnie Lombard Odier SCmA410,000$554K0.0%+24.2%0.113%
10/29/2025 Wealth Enhancement Advisory Services LLC18,877$25K0.0%-74.6%0.005%
10/22/2025 Hennion & Walsh Asset Management Inc.779,212$1.05M0.0%-1.8%0.214%
10/15/2025CWM LLC26,744$36K0.0%-75.5%0.007%
8/18/2025Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%
8/15/2025Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%
8/15/2025Boothbay Fund Management LLC56,120$53K0.0%-87.7%0.015%
8/15/2025Bank of America Corp DE32,097$30K0.0%-66.7%0.009%
8/14/2025Cerity Partners LLC206,279$195K0.0%+21.1%0.057%
8/13/2025Invesco Ltd.420,700$398K0.0%+47.2%0.116%
8/12/2025XTX Topco Ltd66,276$63K0.0%+431.4%0.018%
8/12/2025Catalyst Funds Management Pty Ltd53,700$51K0.0%N/A0.015%
8/8/2025 Geode Capital Management LLC2,377,694$2.25M0.0%-35.6%0.658%
8/7/2025Monaco Asset Management SAM531,600$503K0.1%-27.6%0.147%
8/6/2025 Savant Capital LLC69,578$66K0.0%+33.2%0.019%
7/31/2025 R Squared Ltd29,559$28K0.0%N/A0.008%
7/25/2025Vanguard Personalized Indexing Management LLC65,330$62K0.0%+77.8%0.018%
7/15/2025 Compagnie Lombard Odier SCmA330,000$312K0.0%+200.0%0.091%
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6/27/2025Goldman Sachs Group Inc.355,152$164K0.0%-34.3%0.098%
5/29/2025Rhumbline Advisers137,230$63K0.0%-10.4%0.038%
5/21/2025Acadian Asset Management LLC573,688$263K0.0%N/A0.159%
5/16/2025Goldman Sachs Group Inc.355,152$164K0.0%-34.3%0.098%
5/16/2025AQR Capital Management LLC1,173,225$541K0.0%N/A0.325%
5/15/2025Nantahala Capital Management LLC460,850$212K0.0%-93.0%0.127%
5/15/2025Siren L.L.C.3,516,214$1.62M0.1%-91.0%0.973%
5/14/2025Ieq Capital LLC177,302$82K0.0%N/A0.049%
5/12/2025Invesco Ltd.285,759$132K0.0%+173.5%0.079%
5/9/2025Deutsche Bank AG94,394$43K0.0%-70.1%0.026%


LXRX Institutional Ownership - Frequently Asked Questions

During the previous two years, 94 institutional investors and hedge funds held shares of Lexicon Pharmaceuticals. The most heavily invested institutionals were FMR LLC ($78.29M), Siren L.L.C. ($69.11M), Vanguard Group Inc. ($12.86M), Point72 Asset Management L.P. ($6.64M), Millennium Management LLC ($5.55M), State Street Corp ($3.88M), and UBS Group AG ($3.46M).Learn more on Lexicon Pharmaceuticals' institutional investors.

74.70% of Lexicon Pharmaceuticals' stock is owned by institutional investors. Learn more on LXRX's institutional investor holdings.

Of the 82 institutional investors that purchased Lexicon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: FMR LLC ($11.18M), Point72 Asset Management L.P. ($7.76M), Schonfeld Strategic Advisors LLC ($5.68M), Siren L.L.C. ($5.38M), Nantahala Capital Management LLC ($4.30M), Millennium Management LLC ($3.18M), and UBS Group AG ($2.65M).

Institutional investors have bought a total of 23,249,638 shares in the last 24 months. This purchase volume represents approximately $32.45M in transactions.

Of the 20 institutional investors that sold Lexicon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Schonfeld Strategic Advisors LLC ($3.75M), CIBC Private Wealth Group LLC ($500.40K), Monaco Asset Management SAM ($414.41K), XTX Topco Ltd ($233.45K), GSA Capital Partners LLP ($206.67K), OMERS ADMINISTRATION Corp ($167K), and AQR Capital Management LLC ($158.13K).

Institutional investors have sold a total of 5,857,096 shares in the last 24 months. This volume of shares sold represents approximately $7.76M in transactions.


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Institutional ownership data for NASDAQ:LXRX is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 11/6/2026. New 13F filings are added each quarter as they're published.
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