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Lexicon Pharmaceuticals (LXRX) Institutional Ownership

Lexicon Pharmaceuticals logo
$2.00 +0.32 (+19.05%)
Closing price 04:00 PM Eastern
Extended Trading
$1.95 -0.05 (-2.50%)
As of 05:46 PM Eastern
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Institutional Ownership Changes (13F Filings) for Lexicon Pharmaceuticals (NASDAQ:LXRX)

Current
Institutional Ownership
Percentage
74.70%
Number of
Institutional Buyers
(last 12 months)
42
Total
Institutional Inflows
(last 12 months)
$19.85M
Number of
Institutional Sellers
(last 12 months)
25
Total
Institutional Outflows
(last 12 months)
$30.88M
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LXRX Institutional Buying and Selling by Quarter

Lexicon Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/5/2026 Bank of New York Mellon Corp27,459$43K0.0%+43.6%0.006%
4/29/2026 R Squared Ltd67,526$105K0.1%+45.0%0.016%
2/23/2026Virtu Financial LLC36,468$42K0.0%N/A0.010%
2/19/2026Invesco Ltd.594,883$684K0.0%+14.1%0.164%
2/18/2026XTX Topco Ltd96,090$111K0.0%-70.8%0.026%
2/18/2026Ikarian Capital LLC164,674$189K0.0%-6.7%0.045%
2/18/2026Millennium Management LLC4,821,733$5.55M0.0%+25.9%1.327%
2/18/2026Ishara Investments LP880,000$1.01M1.2%N/A0.242%
2/18/2026Boothbay Fund Management LLC44,315$51K0.0%-21.0%0.012%
2/17/2026AQR Capital Management LLC144,800$167K0.0%-52.2%0.040%
2/17/2026ExodusPoint Capital Management LP268,433$309K0.0%N/A0.074%
2/17/2026Graham Capital Management L.P.109,900$126K0.0%N/A0.030%
2/16/2026OMERS ADMINISTRATION Corp273,800$315K0.0%N/A0.075%
2/16/2026Barclays PLC194,743$224K0.0%+511.2%0.054%
2/13/2026Security National Bank of Sioux City Iowa IA26,650$31K0.0%N/A0.007%
2/13/2026Marshall Wace LLP1,262,367$1.45M0.0%N/A0.347%
2/13/2026Hudson Bay Capital Management LP100,532$116K0.0%N/A0.028%
2/13/2026Quarry LP88,000$101K0.0%N/A0.024%
2/13/2026Headlands Technologies LLC136,113$157K0.0%+174.2%0.037%
2/13/2026Charles Schwab Investment Management Inc.1,055,123$1.21M0.0%-7.8%0.290%
2/12/2026HRT Financial LP117,549$135K0.0%+153.1%0.032%
2/12/2026Renaissance Technologies LLC263,254$303K0.0%-10.0%0.072%
2/12/2026EntryPoint Capital LLC33,618$39K0.0%N/A0.009%
2/12/2026CIBC Private Wealth Group LLC1,950,000$2.24M0.0%-18.8%0.536%
2/11/2026Cerity Partners LLC144,944$167K0.0%-8.3%0.040%
2/11/2026State of Wyoming60,571$70K0.0%+610.4%0.017%
2/10/2026CIBC Asset Management Inc39,520$45K0.0%N/A0.011%
2/10/2026Goldman Sachs Group Inc.921,204$1.06M0.0%+1,452.2%0.253%
2/10/2026Monaco Asset Management SAM117,188$135K0.0%-66.5%0.032%
2/9/2026Geode Capital Management LLC2,500,022$2.88M0.0%+4.3%0.688%
2/6/2026 Leonteq Securities AG30,000$34K0.0%N/A0.008%
2/6/2026GSA Capital Partners LLP996,235$1.15M0.1%-17.2%0.274%
2/5/2026 Pinnacle Associates Ltd.29,015$33K0.0%-42.9%0.008%
1/30/2026 R Squared Ltd46,579$54K0.0%+45.3%0.013%
1/29/2026 UBS Group AG3,007,237$3.46M0.0%+752.1%0.828%
1/14/2026Hennion & Walsh Asset Management Inc.901,222$1.04M0.0%+15.7%0.248%
11/26/2025Vermillion & White Wealth Management Group LLC32,500$44K0.0%+400.0%0.009%
11/24/2025CIBC Private Wealth Group LLC2,400,257$3.24M0.0%-2.0%0.661%
11/21/2025CIBC Bancorp USA Inc.2,400,257$3.24M0.0%N/A0.661%
11/17/2025Jacobs Levy Equity Management Inc.692,727$935K0.0%N/A0.191%
11/17/2025Scientech Research LLC24,884$34K0.0%-57.0%0.007%
11/17/2025Millennium Management LLC3,830,660$5.17M0.0%+133.1%1.054%
11/17/2025Bank of America Corp DE57,804$78K0.0%+80.1%0.016%
11/14/2025Schonfeld Strategic Advisors LLC825,633$1.12M0.0%-82.0%0.227%
11/14/2025Two Sigma Investments LP559,008$755K0.0%+38.4%0.154%
11/14/2025Squarepoint Ops LLC58,676$79K0.0%-38.6%0.016%
11/13/2025Jefferies Financial Group Inc.97,400$131K0.0%N/A0.027%
11/10/2025Optiver Holding B.V.75,893$102K0.0%+2,400.6%0.021%
11/10/2025Monaco Asset Management SAM350,000$472K0.0%-34.2%0.096%
11/10/2025 China Universal Asset Management Co. Ltd.63,698$86K0.0%-12.7%0.018%
11/7/2025GSA Capital Partners LLP1,202,906$1.62M0.1%-57.5%0.331%
11/7/2025Vanguard Group Inc.9,521,874$12.86M0.0%+7.6%2.620%
11/6/2025 Compagnie Lombard Odier SCmA410,000$554K0.0%+24.2%0.113%
10/29/2025 Wealth Enhancement Advisory Services LLC18,877$25K0.0%-74.6%0.005%
10/22/2025Hennion & Walsh Asset Management Inc.779,212$1.05M0.0%-1.8%0.214%
10/15/2025CWM LLC26,744$36K0.0%-75.5%0.007%
8/18/2025Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%
8/15/2025Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%
8/15/2025Boothbay Fund Management LLC56,120$53K0.0%-87.7%0.015%
8/15/2025Bank of America Corp DE32,097$30K0.0%-66.7%0.009%
8/14/2025Cerity Partners LLC206,279$195K0.0%+21.1%0.057%
8/13/2025Invesco Ltd.420,700$398K0.0%+47.2%0.116%
8/12/2025XTX Topco Ltd66,276$63K0.0%+431.4%0.018%
8/12/2025Catalyst Funds Management Pty Ltd53,700$51K0.0%N/A0.015%
8/8/2025Geode Capital Management LLC2,377,694$2.25M0.0%-35.6%0.658%
8/7/2025Monaco Asset Management SAM531,600$503K0.1%-27.6%0.147%
8/6/2025 Savant Capital LLC69,578$66K0.0%+33.2%0.019%
7/31/2025 R Squared Ltd29,559$28K0.0%N/A0.008%
7/25/2025Vanguard Personalized Indexing Management LLC65,330$62K0.0%+77.8%0.018%
7/15/2025 Compagnie Lombard Odier SCmA330,000$312K0.0%+200.0%0.091%
6/27/2025Goldman Sachs Group Inc.355,152$164K0.0%-34.3%0.098%
5/29/2025Rhumbline Advisers137,230$63K0.0%-10.4%0.038%
5/21/2025Acadian Asset Management LLC573,688$263K0.0%N/A0.159%
5/16/2025Goldman Sachs Group Inc.355,152$164K0.0%-34.3%0.098%
5/16/2025AQR Capital Management LLC1,173,225$541K0.0%N/A0.325%
5/15/2025Nantahala Capital Management LLC460,850$212K0.0%-93.0%0.127%
5/15/2025Siren L.L.C.3,516,214$1.62M0.1%-91.0%0.973%
5/14/2025Ieq Capital LLC177,302$82K0.0%N/A0.049%
5/12/2025Invesco Ltd.285,759$132K0.0%+173.5%0.079%
5/9/2025Deutsche Bank AG94,394$43K0.0%-70.1%0.026%
5/9/2025Charles Schwab Investment Management Inc.1,150,771$530K0.0%-3.4%0.318%
5/8/2025Monaco Asset Management SAM734,148$338K0.1%N/A0.203%
5/6/2025Pinnacle Associates Ltd.54,180$25K0.0%-96.2%0.015%
5/1/2025CWM LLC105,504$49K0.0%+9,228.4%0.043%
4/30/2025Cerity Partners LLC170,387$79K0.0%+76.5%0.069%
4/28/2025Straight Path Wealth Management62,666$29K0.0%N/A0.025%
4/16/2025Wealth Enhancement Advisory Services LLC69,207$32K0.0%N/A0.028%
4/10/2025Hennion & Walsh Asset Management Inc.830,054$382K0.0%-3.8%0.337%
3/18/2025California State Teachers Retirement System195,215$144K0.0%+29.9%0.079%
2/17/2025UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC353,508$261K0.0%+193.6%0.144%
2/17/2025Woodline Partners LP229,376$169K0.0%-81.1%0.093%
2/17/2025Tang Capital Management LLC850,268$628K0.0%+750.3%0.345%
2/17/2025Point72 Asset Management L.P.8,988,421$6.64M0.0%+630.7%3.650%
2/17/2025Deutsche Bank AG315,659$234K0.0%+378.0%0.128%
2/17/2025Bank of America Corp DE136,407$101K0.0%+27.4%0.055%
2/17/2025Bayesian Capital Management LP42,000$31K0.0%N/A0.017%
2/14/2025Jane Street Group LLC220,264$163K0.0%+158.0%0.089%
2/14/2025Schonfeld Strategic Advisors LLC7,558,621$5.58M0.0%+301.5%3.070%
2/14/2025Nantahala Capital Management LLC6,604,150$4.88M0.2%+186.6%2.682%
2/14/2025Northern Trust Corp1,308,651$966K0.0%+14.4%0.531%


LXRX Institutional Ownership - Frequently Asked Questions

During the previous two years, 93 institutional investors and hedge funds held shares of Lexicon Pharmaceuticals. The most heavily invested institutionals were FMR LLC ($78.29M), Vanguard Group Inc. ($12.86M), Point72 Asset Management L.P. ($6.64M), Millennium Management LLC ($5.55M), BVF Inc. IL ($4.05M), State Street Corp ($3.88M), and UBS Group AG ($3.46M).Learn more on Lexicon Pharmaceuticals' institutional investors.

74.70% of Lexicon Pharmaceuticals' stock is owned by institutional investors. Learn more on LXRX's institutional investor holdings.

Of the 82 institutional investors that purchased Lexicon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Point72 Asset Management L.P. ($11.30M), FMR LLC ($11.18M), Nantahala Capital Management LLC ($6.60M), Schonfeld Strategic Advisors LLC ($5.68M), Millennium Management LLC ($3.18M), UBS Group AG ($2.65M), and CIBC Bancorp USA Inc. ($2.40M).

Institutional investors have bought a total of 17,512,036 shares in the last 24 months. This purchase volume represents approximately $19.85M in transactions.

Of the 25 institutional investors that sold Lexicon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Siren L.L.C. ($35.40M), Nantahala Capital Management LLC ($6.14M), Schonfeld Strategic Advisors LLC ($3.75M), GSA Capital Partners LLP ($1.83M), Geode Capital Management LLC ($1.31M), Monaco Asset Management SAM ($616.96K), and CIBC Private Wealth Group LLC ($500.40K).

Institutional investors have sold a total of 51,470,799 shares in the last 24 months. This volume of shares sold represents approximately $30.88M in transactions.


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This page (NASDAQ:LXRX) was last updated on 5/8/2026 by MarketBeat.com Staff.
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