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Lexicon Pharmaceuticals (LXRX) Institutional Ownership

Lexicon Pharmaceuticals logo
$2.29 -0.03 (-1.29%)
As of 08/28/2026 04:00 PM Eastern
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Institutional Ownership Changes (13F Filings) for Lexicon Pharmaceuticals (NASDAQ:LXRX)

Current
Institutional Ownership
Percentage
74.70%
Number of
Institutional Buyers
(last 12 months)
41
Total
Institutional Inflows
(last 12 months)
$32.73M
Number of
Institutional Sellers
(last 12 months)
21
Total
Institutional Outflows
(last 12 months)
$9.93M
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LXRX Institutional Buying and Selling by Quarter

Lexicon Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/21/2026 AXQ Capital LP45,727$110K0.0%+126.9%0.010%
8/20/2026 Headlands Technologies LLC167,198$401K0.0%-12.6%0.038%
8/20/2026 Wedbush Securities Inc.20,000$48K0.0%-51.0%0.004%
8/19/2026 Wellington Management Group LLP179,700$431K0.0%N/A0.040%
8/6/2026 Bank of New York Mellon Corp568,706$1.37M0.0%N/A0.128%
5/21/2026 CTC Alternative Strategies Ltd.17,544$27K0.1%N/A0.004%
5/19/2026 Bank of America Corp DE526,103$821K0.0%+415.3%0.118%
5/18/2026 ADAR1 Capital Management LLC750,000$1.17M0.1%N/A0.169%
5/15/2026 OMERS ADMINISTRATION Corp106,800$167K0.0%-61.0%0.024%
5/15/2026 Bridgewater Advisors Inc.82,209$128K0.0%N/A0.019%
5/14/2026 Renaissance Technologies LLC1,600,500$2.50M0.0%+508.0%0.360%
5/14/2026 Siren L.L.C.44,303,518$69.11M1.9%+13.8%9.974%
5/14/2026 Bank of Nova Scotia73,707$115K0.0%N/A0.017%
5/5/2026 Bank of New York Mellon Corp27,459$43K0.0%+43.6%0.006%
4/29/2026 R Squared Ltd67,526$105K0.1%+45.0%0.016%
2/23/2026 Virtu Financial LLC36,468$42K0.0%N/A0.010%
2/19/2026 Invesco Ltd.594,883$684K0.0%+14.1%0.164%
2/18/2026 XTX Topco Ltd96,090$111K0.0%-70.8%0.026%
2/18/2026 Ikarian Capital LLC164,674$189K0.0%-6.7%0.045%
2/18/2026 Millennium Management LLC4,821,733$5.55M0.0%+25.9%1.327%
2/18/2026 Ishara Investments LP880,000$1.01M1.2%N/A0.242%
2/18/2026 Boothbay Fund Management LLC44,315$51K0.0%-21.0%0.012%
2/17/2026 AQR Capital Management LLC144,800$167K0.0%-52.2%0.040%
2/17/2026 ExodusPoint Capital Management LP268,433$309K0.0%N/A0.074%
2/17/2026 Graham Capital Management L.P.109,900$126K0.0%N/A0.030%
2/16/2026 OMERS ADMINISTRATION Corp273,800$315K0.0%N/A0.075%
2/16/2026 Barclays PLC194,743$224K0.0%+511.2%0.054%
2/13/2026Security National Bank of Sioux City Iowa IA26,650$31K0.0%N/A0.007%
2/13/2026 Marshall Wace LLP1,262,367$1.45M0.0%N/A0.347%
2/13/2026 Hudson Bay Capital Management LP100,532$116K0.0%N/A0.028%
2/13/2026 Quarry LP88,000$101K0.0%N/A0.024%
2/13/2026 Headlands Technologies LLC136,113$157K0.0%+174.2%0.037%
2/13/2026 Charles Schwab Investment Management Inc.1,055,123$1.21M0.0%-7.8%0.290%
2/12/2026 HRT Financial LP117,549$135K0.0%+153.1%0.032%
2/12/2026 Renaissance Technologies LLC263,254$303K0.0%-10.0%0.072%
2/12/2026 EntryPoint Capital LLC33,618$39K0.0%N/A0.009%
2/12/2026CIBC Private Wealth Group LLC1,950,000$2.24M0.0%-18.8%0.536%
2/11/2026 Cerity Partners LLC144,944$167K0.0%-8.3%0.040%
2/11/2026 State of Wyoming60,571$70K0.0%+610.4%0.017%
2/10/2026 CIBC Asset Management Inc39,520$45K0.0%N/A0.011%
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2/10/2026 Goldman Sachs Group Inc.921,204$1.06M0.0%+1,452.2%0.253%
2/10/2026 Monaco Asset Management SAM117,188$135K0.0%-66.5%0.032%
2/9/2026 Geode Capital Management LLC2,500,022$2.88M0.0%+4.3%0.688%
2/6/2026 Leonteq Securities AG30,000$34K0.0%N/A0.008%
2/6/2026 GSA Capital Partners LLP996,235$1.15M0.1%-17.2%0.274%
2/5/2026 Pinnacle Associates Ltd.29,015$33K0.0%-42.9%0.008%
1/30/2026 R Squared Ltd46,579$54K0.0%+45.3%0.013%
1/29/2026 UBS Group AG3,007,237$3.46M0.0%+752.1%0.828%
1/14/2026 Hennion & Walsh Asset Management Inc.901,222$1.04M0.0%+15.7%0.248%
11/26/2025 Vermillion & White Wealth Management Group LLC32,500$44K0.0%+400.0%0.009%
11/24/2025CIBC Private Wealth Group LLC2,400,257$3.24M0.0%-2.0%0.661%
11/21/2025 CIBC Bancorp USA Inc.2,400,257$3.24M0.0%N/A0.661%
11/17/2025 Jacobs Levy Equity Management Inc.692,727$935K0.0%N/A0.191%
11/17/2025 Scientech Research LLC24,884$34K0.0%-57.0%0.007%
11/17/2025 Millennium Management LLC3,830,660$5.17M0.0%+133.1%1.054%
11/17/2025 Bank of America Corp DE57,804$78K0.0%+80.1%0.016%
11/14/2025 Schonfeld Strategic Advisors LLC825,633$1.12M0.0%-82.0%0.227%
11/14/2025 Two Sigma Investments LP559,008$755K0.0%+38.4%0.154%
11/14/2025 Squarepoint Ops LLC58,676$79K0.0%-38.6%0.016%
11/13/2025Jefferies Financial Group Inc.97,400$131K0.0%N/A0.027%
11/10/2025 Optiver Holding B.V.75,893$102K0.0%+2,400.6%0.021%
11/10/2025 Monaco Asset Management SAM350,000$472K0.0%-34.2%0.096%
11/10/2025 China Universal Asset Management Co. Ltd.63,698$86K0.0%-12.7%0.018%
11/7/2025 GSA Capital Partners LLP1,202,906$1.62M0.1%-57.5%0.331%
11/7/2025Vanguard Group Inc.9,521,874$12.86M0.0%+7.6%2.620%
11/6/2025 Compagnie Lombard Odier SCmA410,000$554K0.0%+24.2%0.113%
10/29/2025 Wealth Enhancement Advisory Services LLC18,877$25K0.0%-74.6%0.005%
10/22/2025 Hennion & Walsh Asset Management Inc.779,212$1.05M0.0%-1.8%0.214%
10/15/2025CWM LLC26,744$36K0.0%-75.5%0.007%
8/18/2025 Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%
8/15/2025 Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%
8/15/2025 Boothbay Fund Management LLC56,120$53K0.0%-87.7%0.015%
8/15/2025 Bank of America Corp DE32,097$30K0.0%-66.7%0.009%
8/14/2025 Cerity Partners LLC206,279$195K0.0%+21.1%0.057%
8/13/2025 Invesco Ltd.420,700$398K0.0%+47.2%0.116%
8/12/2025 XTX Topco Ltd66,276$63K0.0%+431.4%0.018%
8/12/2025 Catalyst Funds Management Pty Ltd53,700$51K0.0%N/A0.015%
8/8/2025 Geode Capital Management LLC2,377,694$2.25M0.0%-35.6%0.658%
8/7/2025 Monaco Asset Management SAM531,600$503K0.1%-27.6%0.147%
8/6/2025 Savant Capital LLC69,578$66K0.0%+33.2%0.019%
7/31/2025 R Squared Ltd29,559$28K0.0%N/A0.008%
7/25/2025 Vanguard Personalized Indexing Management LLC65,330$62K0.0%+77.8%0.018%
7/15/2025 Compagnie Lombard Odier SCmA330,000$312K0.0%+200.0%0.091%
6/27/2025 Goldman Sachs Group Inc.355,152$164K0.0%-34.3%0.098%
5/29/2025Rhumbline Advisers137,230$63K0.0%-10.4%0.038%
5/21/2025Acadian Asset Management LLC573,688$263K0.0%N/A0.159%
5/16/2025Goldman Sachs Group Inc.355,152$164K0.0%-34.3%0.098%
5/16/2025AQR Capital Management LLC1,173,225$541K0.0%N/A0.325%
5/15/2025Nantahala Capital Management LLC460,850$212K0.0%-93.0%0.127%
5/15/2025Siren L.L.C.3,516,214$1.62M0.1%-91.0%0.973%
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5/14/2025Ieq Capital LLC177,302$82K0.0%N/A0.049%
5/12/2025Invesco Ltd.285,759$132K0.0%+173.5%0.079%
5/9/2025Deutsche Bank AG94,394$43K0.0%-70.1%0.026%
5/9/2025Charles Schwab Investment Management Inc.1,150,771$530K0.0%-3.4%0.318%
5/8/2025Monaco Asset Management SAM734,148$338K0.1%N/A0.203%
5/6/2025Pinnacle Associates Ltd.54,180$25K0.0%-96.2%0.015%
5/1/2025CWM LLC105,504$49K0.0%+9,228.4%0.043%
4/30/2025Cerity Partners LLC170,387$79K0.0%+76.5%0.069%
4/28/2025Straight Path Wealth Management62,666$29K0.0%N/A0.025%
4/16/2025Wealth Enhancement Advisory Services LLC69,207$32K0.0%N/A0.028%


LXRX Institutional Ownership - Frequently Asked Questions

During the previous two years, 91 institutional investors and hedge funds held shares of Lexicon Pharmaceuticals. The most heavily invested institutionals were FMR LLC ($78.29M), Siren L.L.C. ($69.11M), Vanguard Group Inc. ($12.86M), Point72 Asset Management L.P. ($6.64M), Millennium Management LLC ($5.55M), State Street Corp ($3.88M), and UBS Group AG ($3.46M).Learn more on Lexicon Pharmaceuticals' institutional investors.

74.70% of Lexicon Pharmaceuticals' stock is owned by institutional investors. Learn more on LXRX's institutional investor holdings.

Of the 80 institutional investors that purchased Lexicon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: FMR LLC ($11.18M), Point72 Asset Management L.P. ($7.76M), Schonfeld Strategic Advisors LLC ($5.68M), Siren L.L.C. ($5.38M), Nantahala Capital Management LLC ($4.30M), Millennium Management LLC ($3.18M), and UBS Group AG ($2.65M).

Institutional investors have bought a total of 23,622,007 shares in the last 24 months. This purchase volume represents approximately $32.73M in transactions.

Of the 21 institutional investors that sold Lexicon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Schonfeld Strategic Advisors LLC ($3.75M), GSA Capital Partners LLP ($1.83M), CIBC Private Wealth Group LLC ($500.40K), Monaco Asset Management SAM ($414.41K), XTX Topco Ltd ($233.45K), OMERS ADMINISTRATION Corp ($167K), and AQR Capital Management LLC ($158.13K).

Institutional investors have sold a total of 7,511,982 shares in the last 24 months. This volume of shares sold represents approximately $9.93M in transactions.


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Institutional ownership data for NASDAQ:LXRX is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/21/2026. New 13F filings are added each quarter as they're published.
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