Septerna (SEPN) Competitors $10.28 0.00 (0.00%) Closing price 06/11/2025 04:00 PM EasternExtended Trading$10.34 +0.06 (+0.58%) As of 08:12 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock SEPN vs. TWST, IDYA, INDV, APGE, IRON, BHC, ARQT, BHVN, BEAM, and SDGRShould you be buying Septerna stock or one of its competitors? The main competitors of Septerna include Twist Bioscience (TWST), IDEAYA Biosciences (IDYA), Indivior (INDV), Apogee Therapeutics (APGE), Disc Medicine (IRON), Bausch Health Companies (BHC), Arcutis Biotherapeutics (ARQT), Biohaven (BHVN), Beam Therapeutics (BEAM), and Schrödinger (SDGR). These companies are all part of the "pharmaceutical products" industry. Septerna vs. Its Competitors Twist Bioscience IDEAYA Biosciences Indivior Apogee Therapeutics Disc Medicine Bausch Health Companies Arcutis Biotherapeutics Biohaven Beam Therapeutics Schrödinger Septerna (NASDAQ:SEPN) and Twist Bioscience (NASDAQ:TWST) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their media sentiment, dividends, profitability, community ranking, risk, analyst recommendations, valuation, earnings and institutional ownership. Does the media prefer SEPN or TWST? In the previous week, Septerna and Septerna both had 5 articles in the media. Septerna's average media sentiment score of 1.61 beat Twist Bioscience's score of 0.97 indicating that Septerna is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Septerna 2 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Twist Bioscience 2 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has preferable valuation and earnings, SEPN or TWST? Septerna has higher earnings, but lower revenue than Twist Bioscience. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioSepterna$977K468.84N/AN/AN/ATwist Bioscience$347.68M6.06-$208.73M-$3.25-10.82 Is SEPN or TWST more profitable? Septerna has a net margin of 0.00% compared to Twist Bioscience's net margin of -59.76%. Septerna's return on equity of 0.00% beat Twist Bioscience's return on equity.Company Net Margins Return on Equity Return on Assets SepternaN/A N/A N/A Twist Bioscience -59.76%-32.69%-25.25% Do analysts prefer SEPN or TWST? Septerna presently has a consensus target price of $27.00, suggesting a potential upside of 162.65%. Twist Bioscience has a consensus target price of $50.40, suggesting a potential upside of 43.39%. Given Septerna's stronger consensus rating and higher probable upside, equities analysts plainly believe Septerna is more favorable than Twist Bioscience.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Septerna 0 Sell rating(s) 1 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 2.75Twist Bioscience 1 Sell rating(s) 1 Hold rating(s) 8 Buy rating(s) 0 Strong Buy rating(s) 2.70 Does the MarketBeat Community favor SEPN or TWST? Twist Bioscience received 102 more outperform votes than Septerna when rated by MarketBeat users. However, 66.67% of users gave Septerna an outperform vote while only 59.34% of users gave Twist Bioscience an outperform vote. CompanyUnderperformOutperformSepternaOutperform Votes666.67% Underperform Votes333.33% Twist BioscienceOutperform Votes10859.34% Underperform Votes7440.66% SummarySepterna beats Twist Bioscience on 8 of the 11 factors compared between the two stocks. Get Septerna News Delivered to You Automatically Sign up to receive the latest news and ratings for SEPN and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SEPN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SEPN vs. The Competition Export to ExcelMetricSepternaPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$458.06M$6.85B$5.57B$8.63BDividend YieldN/A2.55%5.28%4.18%P/E RatioN/A8.7827.1420.06Price / Sales468.84255.64411.98157.10Price / CashN/A65.8538.2534.64Price / BookN/A6.557.064.70Net IncomeN/A$143.93M$3.23B$247.88M7 Day Performance-2.28%3.84%2.85%2.63%1 Month Performance47.28%11.20%9.06%6.36%1 Year PerformanceN/A4.18%31.43%14.05% Septerna Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SEPNSepterna2.217 of 5 stars$10.28flat$27.00+162.6%N/A$458.06M$977K0.00N/APositive NewsAnalyst RevisionTWSTTwist Bioscience4.2375 of 5 stars$31.07+6.0%$50.40+62.2%-31.9%$1.76B$347.68M-9.19990IDYAIDEAYA Biosciences4.0159 of 5 stars$21.22+6.7%$54.27+155.8%-41.7%$1.74B$7M-6.4380Positive NewsAnalyst RevisionINDVIndivior2.6396 of 5 stars$12.46-3.1%$15.00+20.4%-19.0%$1.72B$1.17B-35.601,164Positive NewsAPGEApogee Therapeutics2.1544 of 5 stars$36.33-0.8%$94.60+160.4%-1.8%$1.67BN/A-15.0191IRONDisc Medicine2.4181 of 5 stars$47.73+2.2%$98.80+107.0%+30.0%$1.65BN/A-11.9930Positive NewsAnalyst ForecastInsider TradeAnalyst RevisionBHCBausch Health Companies4.1517 of 5 stars$4.49-1.0%$7.42+65.4%-12.8%$1.64B$9.73B-37.3719,900Positive NewsARQTArcutis Biotherapeutics2.1035 of 5 stars$13.48+3.4%$18.80+39.5%+76.5%$1.61B$212.82M-7.53150Gap UpBHVNBiohaven3.0201 of 5 stars$15.62+5.4%$59.46+280.8%-54.3%$1.59BN/A-1.67239Trending NewsShort Interest ↑Analyst RevisionHigh Trading VolumeBEAMBeam Therapeutics3.2857 of 5 stars$16.19+2.3%$48.75+201.1%-28.0%$1.59B$63.58M-9.20510Positive NewsAnalyst RevisionSDGRSchrödinger1.6772 of 5 stars$21.69+0.3%$32.80+51.2%+27.1%$1.59B$230.49M-9.27790 Related Companies and Tools Related Companies TWST Competitors IDYA Competitors INDV Competitors APGE Competitors IRON Competitors BHC Competitors ARQT Competitors BHVN Competitors BEAM Competitors SDGR Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SEPN) was last updated on 6/12/2025 by MarketBeat.com Staff From Our PartnersTrump’s Exec Order #14154 could be a “Millionaire-Maker”Former Presidential Advisor, Jim Rickards, says Trump could “rewire our economy and hand millions of Americans...Paradigm Press | SponsoredTrump wipes out trillions overnight…Is there anybody more powerful than Donald Trump right now? In a single tariff announcement, he wiped out n...Porter & Company | SponsoredNew Rule Hits in July — The Smart Money Already MovedA little-known regulation quietly goes into effect this July. And it's already being exploited by Wall Stre...American Alternative | SponsoredGold is soaring. Here’s how to get paid from itGold just broke through $3,300… And while the headlines shout about price targets, something even more powe...Investors Alley | SponsoredGold Hits New Highs as Global Markets SpiralWhen Trump took office in 2017, gold was just $1,100 an ounce. By the time he left, it had soared to $1,839. ...Premier Gold Co | Sponsored[No Brainer Gold Play]: “Show me a better investment.”A Historic Gold Announcement Is About to Rock Wall Street? For months, sharp-eyed analysts have watched the...Golden Portfolio | SponsoredIs Elon's empire crumbling?The Tesla Shock Nobody Sees Coming While headlines scream "Tesla is doomed"... Jeff Brown has uncovered ...Brownstone Research | SponsoredMarch 16th -- America’s most important day?50-Year Legend: Here's The Day Stocks Likely Crash Legendary quant analyst Marc Chaikin says in 50 years on...Chaikin Analytics | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added five stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding Septerna, Inc. Please log in to your account or sign up in order to add this asset to your watchlist. Share Septerna With A Colleague Link copied to clipboard. Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Buy SEPN Stock Free SEPN Stock Alerts