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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
$34.64
+0.9%
$33.99
$29.08
$50.79
$1.11B0.74352,765 shs278,460 shs
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
$13.50
-1.6%
$19.32
$8.46
$45.00
$320.14M-0.09111,029 shs99,935 shs
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
$5.87
+1.0%
$6.76
$5.02
$21.73
$1.12B-1.333.65 million shs2.24 million shs
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
$6.79
-2.0%
$6.19
$4.30
$10.08
$1.20B0.781.45 million shs1.64 million shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
-1.32%+5.05%-3.78%-0.46%+15.66%
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
+3.78%+5.13%-28.73%-35.44%+45.80%
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
+2.65%-4.60%-14.43%-55.38%-19.19%
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
+3.28%+12.68%+10.70%+26.92%+58.22%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
$34.64
+0.9%
$33.99
$29.08
$50.79
$1.11B0.74352,765 shs278,460 shs
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
$13.50
-1.6%
$19.32
$8.46
$45.00
$320.14M-0.09111,029 shs99,935 shs
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
$5.87
+1.0%
$6.76
$5.02
$21.73
$1.12B-1.333.65 million shs2.24 million shs
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
$6.79
-2.0%
$6.19
$4.30
$10.08
$1.20B0.781.45 million shs1.64 million shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
-1.32%+5.05%-3.78%-0.46%+15.66%
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
+3.78%+5.13%-28.73%-35.44%+45.80%
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
+2.65%-4.60%-14.43%-55.38%-19.19%
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
+3.28%+12.68%+10.70%+26.92%+58.22%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
2.67
Moderate Buy$57.5065.99% Upside
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
2.71
Moderate Buy$43.00218.52% Upside
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
2.87
Moderate Buy$26.41349.94% Upside
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
2.43
Hold$10.8059.06% Upside

Current Analyst Ratings Breakdown

Latest LYEL, WVE, COLL, and XERS Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
6/11/2026
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
Set Price Target$13.00
6/11/2026
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
Reiterated RatingBuy
6/9/2026
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
Reiterated RatingMarket Outperform
6/9/2026
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
Reiterated RatingBuy$45.00
6/8/2026
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
Reiterated RatingBuy$44.00
6/3/2026
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
Set Price Target$45.00
6/3/2026
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
Reiterated RatingBuy$45.00
5/20/2026
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
Boost Price TargetOverweight$13.00 ➝ $14.00
5/19/2026
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
Lower Price TargetBuy$18.00 ➝ $13.00
5/18/2026
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
UpgradeStrong SellHold
5/11/2026
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
DowngradeHold (C-)Sell (D+)
(Data available from 6/12/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
$780.57M1.44$15.33 per share2.26$9.54 per share3.63
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
$40K7,873.88N/AN/A$11.68 per share1.16
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
$42.73M26.43N/AN/A$3.10 per share1.89
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
$291.85M4.02$0.10 per share69.18$0.08 per share84.88
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
$62.87M$2.0416.985.86N/A9.41%95.18%16.39%8/6/2026 (Estimated)
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
-$274.45M-$13.80N/AN/AN/A-794,858.12%-85.71%-66.41%8/11/2026 (Estimated)
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
-$204.38M-$1.06N/AN/AN/A-255.70%-56.76%-42.80%7/30/2026 (Estimated)
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
$550K$0.06113.1719.97N/A3.81%735.00%3.24%8/6/2026 (Estimated)

Latest LYEL, WVE, COLL, and XERS Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/7/2026Q1 2026
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
$1.52$1.76+$0.24$0.40$184.47 million$193.52 million
5/7/2026Q1 2026
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
-$0.0027$0.01+$0.0127$0.01$79.83 million$83.13 million
5/6/2026Q1 2026
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
-$1.10-$1.10N/A-$1.10$0.00 million$0.00 million
4/29/2026Q1 2026
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
-$0.34-$0.13+$0.21-$0.13$8.45 million$38.25 million
3/12/2026Q4 2025
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
-$2.15-$7.68-$5.53-$7.68$0.02 million$0.01 million
CompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive Growth
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
N/AN/AN/AN/AN/A
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
N/AN/AN/AN/AN/A
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
N/AN/AN/AN/AN/A
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
2.47
1.71
1.62
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
N/A
7.23
7.23
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
N/A
11.26
11.26
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
17.00
2.12
1.50

Institutional Ownership

CompanyInstitutional Ownership
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
N/A
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
66.05%
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
89.73%
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
42.75%

Insider Ownership

CompanyInsider Ownership
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
1.85%
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
6.20%
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
24.30%
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
4.35%
CompanyEmployeesShares OutstandingFree FloatOptionable
Collegium Pharmaceutical, Inc. stock logo
COLL
Collegium Pharmaceutical
21032.43 million31.83 millionOptionable
Lyell Immunopharma, Inc. stock logo
LYEL
Lyell Immunopharma
27023.33 million21.89 millionOptionable
WAVE Life Sciences Ltd. stock logo
WVE
WAVE Life Sciences
240192.40 million145.65 millionOptionable
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
290172.64 million165.13 millionOptionable

Recent News About These Companies

Xeris Biopharma Announces Private Exchange of Convertible Notes
Xeris Biopharma: Q1 Earnings Snapshot

New MarketBeat Followers Over Time

Media Sentiment Over Time

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Collegium Pharmaceutical stock logo

Collegium Pharmaceutical NASDAQ:COLL

$34.64 +0.30 (+0.87%)
Closing price 04:00 PM Eastern
Extended Trading
$34.62 -0.02 (-0.06%)
As of 04:10 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, engages in the development and commercialization of medicines for pain management. Its portfolio includes Xtampza ER, an abuse-deterrent, extended-release, and oral formulation of oxycodone for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment; Nucynta ER and Nucynta IR, which are extended-release and immediate-release formulations of tapentadol, indicated for the management of acute, severe, and persistent pain; Belbuca, a buccal film that contains buprenorphine; and Symproic, an oral formulation of naldemedine for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain. The company was formerly known as Collegium Pharmaceuticals, Inc. and changed its name to Collegium Pharmaceutical, Inc. in October 2003. Collegium Pharmaceutical, Inc. was incorporated in 2002 and is headquartered in Stoughton, Massachusetts.

Lyell Immunopharma stock logo

Lyell Immunopharma NASDAQ:LYEL

$13.50 -0.22 (-1.60%)
Closing price 04:00 PM Eastern
Extended Trading
$13.51 +0.01 (+0.07%)
As of 04:10 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops T cell reprogramming technologies for patients with solid tumors. The company develops therapies using an ex vivo genetic reprogramming technologies, such as c Jun overexpression and NR4A3 gene knockout, to endow resistance to T cell exhaustion; and an ex vivo epigenetic reprogramming technologies, including Epi R to generate population of T cells with durable stemness, and Stim R, a proprietary synthetic cell mimetic. It is also developing LYL797, a genetically and epigenetically reprogrammed ROR1 chimeric antigen receptor (CAR) T cell product candidate that is in Phase 1 clinical trial for the treatment of various solid tumors; and LYL845, a novel epigenetically reprogrammed tumor-infiltrating lymphocytes product candidate, which is in Phase 1 clinical trial targeting multiple solid tumor indications. In addition, the company's preclinical product candidates include LYL119, a ROR1 CAR T-cell product for the treatment of enhanced cytotoxicity; and second generation TIL product. Lyell Immunopharma, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California.

WAVE Life Sciences stock logo

WAVE Life Sciences NASDAQ:WVE

$5.87 +0.06 (+1.03%)
Closing price 04:00 PM Eastern
Extended Trading
$5.83 -0.04 (-0.75%)
As of 07:54 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company's RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, a RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; siRNA clinical candidate for the treatment of obesity and other metabolic disorders; WVE-N531, a exon skipping oligonucleotide for the treatment of duchenne muscular dystrophy; and WVE-003, an antisense silencing oligonucleotide for the treatment of Huntington's disease (HD). The company has collaboration agreements with GlaxoSmithKline for the research, development, and commercialization of oligonucleotide therapeutics; Takeda Pharmaceutical Company Limited for the research, development, and commercialization of oligonucleotide therapeutics for disorders of the Central Nervous System; and Asuragen, Inc. for the development and potential commercialization of companion diagnostics for investigational allele-selective therapeutic programs targeting HD. Wave Life Sciences Ltd. was incorporated in 2012 and is based in Singapore.

Xeris Biopharma stock logo

Xeris Biopharma NASDAQ:XERS

$6.79 -0.14 (-2.02%)
Closing price 04:00 PM Eastern
Extended Trading
$6.84 +0.05 (+0.81%)
As of 07:32 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Xeris Biopharma Holdings, Inc., a biopharmaceutical company, engages in developing and commercializing therapies in Illinois. The company offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor proved for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase I clinical trial for the treatment of hypothyroidism; and non-aqueous XeriSol and XeriJect technologies for various therapies. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.