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Aprea Therapeutics (APRE) Competitors

Aprea Therapeutics logo
$1.60 -0.15 (-8.57%)
Closing price 05/21/2025 03:59 PM Eastern
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$1.72 +0.13 (+7.81%)
As of 08:07 AM Eastern
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APRE vs. SPRO, LVTX, AKTX, COEP, FBLG, DYAI, BLUE, KZR, FGEN, and MRNS

Should you be buying Aprea Therapeutics stock or one of its competitors? The main competitors of Aprea Therapeutics include Spero Therapeutics (SPRO), LAVA Therapeutics (LVTX), Akari Therapeutics (AKTX), Coeptis Therapeutics (COEP), FibroBiologics (FBLG), Dyadic International (DYAI), bluebird bio (BLUE), Kezar Life Sciences (KZR), FibroGen (FGEN), and Marinus Pharmaceuticals (MRNS). These companies are all part of the "pharmaceutical products" industry.

Aprea Therapeutics vs.

Aprea Therapeutics (NASDAQ:APRE) and Spero Therapeutics (NASDAQ:SPRO) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, valuation, dividends, media sentiment, profitability, institutional ownership, community ranking, analyst recommendations and risk.

In the previous week, Aprea Therapeutics had 6 more articles in the media than Spero Therapeutics. MarketBeat recorded 7 mentions for Aprea Therapeutics and 1 mentions for Spero Therapeutics. Spero Therapeutics' average media sentiment score of 0.00 beat Aprea Therapeutics' score of -0.16 indicating that Spero Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aprea Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Spero Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Spero Therapeutics received 153 more outperform votes than Aprea Therapeutics when rated by MarketBeat users. Likewise, 69.67% of users gave Spero Therapeutics an outperform vote while only 57.14% of users gave Aprea Therapeutics an outperform vote.

CompanyUnderperformOutperform
Aprea TherapeuticsOutperform Votes
56
57.14%
Underperform Votes
42
42.86%
Spero TherapeuticsOutperform Votes
209
69.67%
Underperform Votes
91
30.33%

34.2% of Aprea Therapeutics shares are owned by institutional investors. Comparatively, 25.6% of Spero Therapeutics shares are owned by institutional investors. 12.8% of Aprea Therapeutics shares are owned by company insiders. Comparatively, 4.5% of Spero Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Aprea Therapeutics presently has a consensus target price of $15.50, suggesting a potential upside of 868.75%. Spero Therapeutics has a consensus target price of $5.00, suggesting a potential upside of 629.08%. Given Aprea Therapeutics' stronger consensus rating and higher possible upside, equities research analysts clearly believe Aprea Therapeutics is more favorable than Spero Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aprea Therapeutics
0 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
3.00
Spero Therapeutics
0 Sell rating(s)
2 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.50

Aprea Therapeutics has a beta of 1.18, meaning that its stock price is 18% more volatile than the S&P 500. Comparatively, Spero Therapeutics has a beta of 0.23, meaning that its stock price is 77% less volatile than the S&P 500.

Spero Therapeutics has a net margin of 3.30% compared to Aprea Therapeutics' net margin of -1,029.50%. Spero Therapeutics' return on equity of 4.03% beat Aprea Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aprea Therapeutics-1,029.50% -57.86% -47.94%
Spero Therapeutics 3.30%4.03%2.21%

Spero Therapeutics has higher revenue and earnings than Aprea Therapeutics. Aprea Therapeutics is trading at a lower price-to-earnings ratio than Spero Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aprea Therapeutics$580K15.26-$14.29M-$2.37-0.68
Spero Therapeutics$28.30M1.35$22.81M-$1.28-0.54

Summary

Spero Therapeutics beats Aprea Therapeutics on 10 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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APRE vs. The Competition

MetricAprea TherapeuticsPharmaceutical IndustryMedical SectorNASDAQ Exchange
Market Cap$8.85M$6.53B$5.38B$8.39B
Dividend YieldN/A2.64%5.21%4.10%
P/E Ratio-0.578.9226.7619.71
Price / Sales15.26252.24389.71117.54
Price / CashN/A65.8538.2534.62
Price / Book0.356.466.784.50
Net Income-$14.29M$143.98M$3.23B$248.18M
7 Day Performance-11.11%2.03%1.51%0.23%
1 Month Performance3.23%4.11%10.03%12.39%
1 Year Performance-68.19%-2.87%16.65%7.07%

Aprea Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
APRE
Aprea Therapeutics
3.0606 of 5 stars
$1.60
-8.6%
$15.50
+868.8%
-68.6%$8.85M$580,000.00-0.577Analyst Revision
Gap Down
SPRO
Spero Therapeutics
4.1216 of 5 stars
$0.61
-1.6%
$5.00
+719.7%
-54.6%$34.11M$27.40M8.72150
LVTX
LAVA Therapeutics
2.2168 of 5 stars
$1.28
+2.3%
$3.17
+147.6%
-50.2%$33.64M$11.98M-1.2460Analyst Revision
AKTX
Akari Therapeutics
N/A$1.41
+11.9%
N/A-24.2%$33.51MN/A0.009Analyst Forecast
Gap Down
COEP
Coeptis Therapeutics
0.7074 of 5 stars
$9.90
+4.2%
N/A+45.5%$33.31MN/A-1.712Positive News
FBLG
FibroBiologics
1.5636 of 5 stars
$0.87
+4.7%
$13.00
+1,394.3%
-91.7%$33.29MN/A-2.5610
DYAI
Dyadic International
2.2771 of 5 stars
$1.10
+2.8%
$6.00
+445.5%
-38.3%$33.10M$3.50M-4.787
BLUE
bluebird bio
2.7073 of 5 stars
$3.29
-6.0%
$44.60
+1,255.6%
-75.1%$32.21M$83.81M-0.09520High Trading Volume
KZR
Kezar Life Sciences
4.1523 of 5 stars
$4.23
+0.2%
$39.50
+833.8%
-48.3%$30.90M$7M-0.3260
FGEN
FibroGen
4.3773 of 5 stars
$0.31
-0.8%
$10.00
+3,174.4%
-72.1%$30.86M$29.62M-0.25570
MRNS
Marinus Pharmaceuticals
1.8693 of 5 stars
$0.55
-0.2%
$4.79
+771.6%
-58.7%$30.32M$30.99M-0.22110News Coverage
Analyst Forecast

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This page (NASDAQ:APRE) was last updated on 5/22/2025 by MarketBeat.com Staff
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