Puma Biotechnology (PBYI) Competitors $4.47 -0.03 (-0.67%) Closing price 09/12/2025 04:00 PM EasternExtended Trading$4.47 0.00 (0.00%) As of 09/12/2025 06:50 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock PBYI vs. ADMA, CTMX, TRDA, SPRY, PRAX, QURE, ATAI, CRON, CRMD, and TSHAShould you be buying Puma Biotechnology stock or one of its competitors? The main competitors of Puma Biotechnology include ADMA Biologics (ADMA), CytomX Therapeutics (CTMX), Entrada Therapeutics (TRDA), ARS Pharmaceuticals (SPRY), Praxis Precision Medicines (PRAX), uniQure (QURE), atai Life Sciences (ATAI), Cronos Group (CRON), CorMedix (CRMD), and Taysha Gene Therapies (TSHA). These companies are all part of the "pharmaceutical products" industry. Puma Biotechnology vs. Its Competitors ADMA Biologics CytomX Therapeutics Entrada Therapeutics ARS Pharmaceuticals Praxis Precision Medicines uniQure atai Life Sciences Cronos Group CorMedix Taysha Gene Therapies ADMA Biologics (NASDAQ:ADMA) and Puma Biotechnology (NASDAQ:PBYI) are both medical companies, but which is the better business? We will compare the two companies based on the strength of their profitability, earnings, valuation, institutional ownership, dividends, media sentiment, analyst recommendations and risk. Which has preferable earnings and valuation, ADMA or PBYI? ADMA Biologics has higher revenue and earnings than Puma Biotechnology. Puma Biotechnology is trading at a lower price-to-earnings ratio than ADMA Biologics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioADMA Biologics$426.45M9.01$197.67M$0.8618.73Puma Biotechnology$230.50M0.98$30.28M$0.984.56 Is ADMA or PBYI more profitable? ADMA Biologics has a net margin of 44.06% compared to Puma Biotechnology's net margin of 20.38%. Puma Biotechnology's return on equity of 53.15% beat ADMA Biologics' return on equity.Company Net Margins Return on Equity Return on Assets ADMA Biologics44.06% 41.01% 28.47% Puma Biotechnology 20.38%53.15%23.51% Do institutionals and insiders believe in ADMA or PBYI? 75.7% of ADMA Biologics shares are held by institutional investors. Comparatively, 61.3% of Puma Biotechnology shares are held by institutional investors. 3.5% of ADMA Biologics shares are held by insiders. Comparatively, 23.3% of Puma Biotechnology shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth. Does the media prefer ADMA or PBYI? In the previous week, Puma Biotechnology had 1 more articles in the media than ADMA Biologics. MarketBeat recorded 3 mentions for Puma Biotechnology and 2 mentions for ADMA Biologics. ADMA Biologics' average media sentiment score of 1.43 beat Puma Biotechnology's score of 1.40 indicating that ADMA Biologics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment ADMA Biologics 0 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Puma Biotechnology 1 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do analysts prefer ADMA or PBYI? ADMA Biologics presently has a consensus price target of $27.67, indicating a potential upside of 71.74%. Puma Biotechnology has a consensus price target of $7.00, indicating a potential upside of 56.60%. Given ADMA Biologics' stronger consensus rating and higher probable upside, equities research analysts plainly believe ADMA Biologics is more favorable than Puma Biotechnology.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score ADMA Biologics 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 1 Strong Buy rating(s) 3.33Puma Biotechnology 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 3.00 Which has more risk and volatility, ADMA or PBYI? ADMA Biologics has a beta of 0.54, suggesting that its share price is 46% less volatile than the S&P 500. Comparatively, Puma Biotechnology has a beta of 1.38, suggesting that its share price is 38% more volatile than the S&P 500. SummaryADMA Biologics beats Puma Biotechnology on 12 of the 17 factors compared between the two stocks. Get Puma Biotechnology News Delivered to You Automatically Sign up to receive the latest news and ratings for PBYI and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding PBYI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart PBYI vs. The Competition Export to ExcelMetricPuma BiotechnologyMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$226.67M$3.19B$5.85B$10.14BDividend YieldN/A2.30%5.68%4.60%P/E Ratio4.5621.4375.4125.98Price / Sales0.98429.44515.81181.13Price / Cash5.2846.6837.5660.44Price / Book2.389.6112.156.29Net Income$30.28M-$53.29M$3.29B$271.07M7 Day Performance-11.13%0.13%0.74%3.87%1 Month Performance-15.66%5.61%4.81%4.88%1 Year Performance76.68%10.49%60.57%26.12% Puma Biotechnology Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)PBYIPuma Biotechnology4.0102 of 5 stars$4.47-0.7%$7.00+56.6%+78.1%$226.67M$230.50M4.56200Positive NewsADMAADMA Biologics3.7009 of 5 stars$16.42-2.7%$27.67+68.5%-8.7%$4.03B$426.45M19.09530Positive NewsCTMXCytomX Therapeutics4.1454 of 5 stars$2.18-4.4%$5.75+163.8%+60.0%$376M$138.10M3.89170News CoveragePositive NewsTRDAEntrada Therapeutics2.624 of 5 stars$5.28-0.2%$25.67+386.1%-64.5%$201.22M$210.78M-2.97110News CoveragePositive NewsSPRYARS Pharmaceuticals2.6519 of 5 stars$10.70+6.3%$32.50+203.7%-20.6%$995.18M$89.15M-21.8490PRAXPraxis Precision Medicines2.305 of 5 stars$40.75-13.0%$85.88+110.7%-35.8%$985.99M$8.55M-3.32110Positive NewsGap DownHigh Trading VolumeQUREuniQure3.2133 of 5 stars$17.43-2.9%$37.45+114.9%+197.7%$984.86M$27.12M-4.45500ATAIatai Life Sciences2.8866 of 5 stars$4.52-1.1%$11.25+148.9%+276.4%$979.53M$310K-6.5580Positive NewsCRONCronos Group2.4812 of 5 stars$2.48-0.8%N/A+17.1%$957.23M$117.61M49.60450CRMDCorMedix3.9113 of 5 stars$12.75+2.8%$17.33+35.9%+88.6%$925.65M$43.47M17.0030Trending NewsAnalyst ForecastInsider TradeShort Interest ↑TSHATaysha Gene Therapies2.2708 of 5 stars$3.24-3.6%$8.29+155.7%+40.2%$916.59M$8.33M-9.53180News CoverageInsider Trade Related Companies and Tools Related Companies ADMA Biologics Competitors CytomX Therapeutics Competitors Entrada Therapeutics Competitors ARS Pharmaceuticals Competitors Praxis Precision Medicines Competitors uniQure Competitors atai Life Sciences Competitors Cronos Group Competitors CorMedix Competitors Taysha Gene Therapies Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:PBYI) was last updated on 9/13/2025 by MarketBeat.com Staff From Our PartnersHe Called Nvidia at $1.10. 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