Septerna (SEPN) Stock Chart & Stock Price History $16.00 +0.30 (+1.91%) Closing price 04:00 PM EasternExtended Trading$15.86 -0.14 (-0.87%) As of 07:50 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock Septerna Stock Price Performance The Septerna (SEPN) stock chart highlights key performance trends across multiple timeframes. Since the beginning of the year, the stock decreased 30.13%. In the past month, the stock has increased 33.44%, reflecting recent market activity. As of the latest close, Septerna traded at $15.70 with a market cap of $699.98 million and volume of 653,479 shares. 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Read our full terms of service and privacy policy. 5 Day Performance+11.19%1 Month Performance+33.44%3 Month Performance+52.82%Year-To-Date Performance-30.13% SEPN Stock Chart for Monday, September, 22, 2025 SEPN Chart by TradingView Septerna Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame Start Date End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization09/22/2025$15.70$16.00+1.91%$16.20$15.41205,824 shs$713.36 million09/19/2025$15.94$15.70-1.51%$16.12$15.50653,479 shs$699.98 million09/18/2025$14.39$15.94+10.77%$15.98$14.52259,044 shs$710.61 million09/17/2025$14.44$14.39-0.35%$14.91$14.35186,401 shs$641.51 million09/16/2025$14.47$14.44-0.21%$14.69$14.36118,702 shs$643.81 million09/15/2025$14.28$14.47+1.33%$14.51$14.00165,690 shs$645.07 million09/12/2025$14.42$14.28-0.97%$14.50$14.11161,831 shs$636.60 million09/11/2025$14.72$14.42-2.04%$14.82$13.67251,781 shs$642.84 million09/10/2025$15.22$14.72-3.29%$15.50$14.58206,369 shs$656.29 million09/09/2025$14.67$15.22+3.75%$15.26$14.38156,599 shs$678.51 million Get the Latest News and Ratings for SEPN and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Septerna and its competitors with MarketBeat's FREE daily newsletter. 09/08/2025$14.43$14.67+1.66%$14.77$14.22182,102 shs$653.99 million09/05/2025$14.12$14.43+2.20%$14.62$13.98202,291 shs$643.29 million09/04/2025$14.08$14.12+0.28%$14.37$13.75355,246 shs$629.54 million09/03/2025$12.34$14.08+14.10%$14.39$12.33798,304 shs$627.69 million09/02/2025$12.10$12.34+1.98%$12.42$11.98115,717 shs$550.12 million09/01/2025$12.10$12.10$12.30$11.70197,661 shs$539.48 million08/29/2025$12.28$12.10-1.47%$12.30$11.70197,661 shs$539.48 million08/28/2025$12.63$12.28-2.77%$12.76$12.27187,645 shs$547.44 million08/27/2025$12.70$12.63-0.55%$12.87$12.47195,700 shs$563.05 million08/26/2025$11.96$12.70+6.19%$12.76$11.97119,143 shs$566.23 million08/25/2025$11.99$11.96-0.25%$12.53$11.91243,972 shs$533.18 million08/22/2025$11.70$11.99+2.48%$12.74$11.73362,953 shs$534.51 million08/21/2025$11.09$11.70+5.50%$11.72$10.91142,812 shs$521.59 million Related Companies CPRX Stock Chart ALVO Stock Chart MLYS Stock Chart BEAM Stock Chart OCUL Stock Chart IDYA Stock Chart BLTE Stock Chart AGIO Stock Chart ANIP Stock Chart IRON Stock Chart Receive SEPN Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Septerna and its competitors with MarketBeat's FREE daily newsletter. 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