Upstream Bio (UPB) Stock Chart & Stock Price History $9.31 +0.38 (+4.26%) Closing price 05/22/2025 04:00 PM EasternExtended Trading$9.33 +0.02 (+0.21%) As of 05/22/2025 04:04 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock Upstream Bio Stock Price Performance The Upstream Bio (UPB) stock chart highlights key performance trends across multiple timeframes. Since the beginning of the year, the stock decreased 43.37%. In the past month, the stock has increased 5.68%, reflecting recent market activity. As of the latest close, Upstream Bio traded at $9.31 with a market cap of $500.82 million and volume of 384,165 shares. 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Email Address 5 Day Performance+7.75%1 Month Performance+5.68%3 Month Performance+16.67%Year-To-Date Performance-43.37% UPB Stock Chart for Friday, May, 23, 2025 UPB Chart by TradingView Upstream Bio Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame * Start Date * End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization05/22/2025$8.93$9.31+4.26%$9.56$8.48384,165 shs$500.82 million05/21/2025$9.13$8.93-2.19%$9.47$8.70282,305 shs$480.38 million05/20/2025$9.05$9.13+0.88%$9.33$8.63398,528 shs$491.14 million05/19/2025$8.64$9.05+4.75%$9.31$8.50385,483 shs$486.84 million05/16/2025$8.78$8.64-1.59%$9.38$8.62318,862 shs$464.78 million05/15/2025$8.56$8.78+2.57%$8.89$8.25237,936 shs$472.31 million05/14/2025$8.65$8.56-1.04%$8.81$7.99356,782 shs$460.48 million05/13/2025$9.50$8.65-8.95%$9.69$8.60321,024 shs$465.32 million05/12/2025$8.73$9.50+8.82%$9.70$8.24174,736 shs$511.04 million05/09/2025$8.83$8.73-1.13%$9.40$8.53324,835 shs$468.71 million Get the Latest News and Ratings for UPB and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 05/08/2025$8.58$8.83+2.91%$8.99$7.88218,387 shs$474.07 million05/07/2025$8.21$8.58+4.51%$9.17$8.06253,041 shs$460.65 million05/06/2025$8.68$8.21-5.41%$8.90$7.79906,996 shs$440.79 million05/05/2025$8.64$8.68+0.46%$8.83$7.95491,615 shs$466.02 million05/02/2025$9.00$8.64-4.00%$9.29$8.63484,378 shs$463.87 million05/01/2025$9.26$9.00-2.81%$9.49$8.75267,173 shs$483.20 million04/30/2025$8.98$9.26+3.12%$9.41$8.59189,688 shs$497.16 million04/29/2025$8.78$8.98+2.28%$9.82$8.55216,944 shs$482.13 million04/28/2025$8.39$8.78+4.65%$8.85$7.93291,529 shs$471.39 million04/25/2025$8.96$8.39-6.36%$8.86$8.20232,948 shs$450.05 million04/24/2025$8.81$8.96+1.70%$9.08$8.52227,944 shs$480.62 million04/23/2025$10.15$8.81-13.20%$10.50$8.53397,908 shs$472.58 million04/22/2025$9.71$10.15+4.53%$10.19$9.64324,849 shs$544.46 million Related Companies TWST Stock Price Chart BLTE Stock Price Chart KNSA Stock Price Chart ARWR Stock Price Chart CGON Stock Price Chart GMTX Stock Price Chart TVTX Stock Price Chart RXRX Stock Price Chart TARS Stock Price Chart BEAM Stock Price Chart Receive UPB Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 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