Upstream Bio (UPB) Stock Chart & Stock Price History $15.96 +0.12 (+0.74%) Closing price 03:59 PM EasternExtended Trading$15.98 +0.03 (+0.18%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock Upstream Bio Stock Price Performance The Upstream Bio (UPB) stock chart highlights key performance trends across multiple timeframes. Since the beginning of the year, the stock decreased 2.94%. In the past month, the stock has increased 46.39%, reflecting recent market activity. As of the latest close, Upstream Bio traded at $15.84 with a market cap of $852.03 million and volume of 371,732 shares. 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Email Address 5 Day Performance+2.68%1 Month Performance+46.39%3 Month Performance+80.71%Year-To-Date Performance-2.94% UPB Stock Chart for Friday, August, 8, 2025 UPB Chart by TradingView Upstream Bio Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame Start Date End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization08/07/2025$16.72$15.84-5.26%$17.57$15.81371,732 shs$852.03 million08/06/2025$15.50$16.72+7.87%$16.80$15.05366,682 shs$899.37 million08/05/2025$15.61$15.50-0.70%$16.06$15.45359,635 shs$833.81 million08/04/2025$15.54$15.61+0.45%$15.88$15.04410,281 shs$839.66 million08/01/2025$15.31$15.54+1.50%$15.60$14.21514,108 shs$835.90 million07/31/2025$15.19$15.31+0.79%$16.15$15.02567,996 shs$823.53 million07/30/2025$13.97$15.19+8.73%$15.47$13.99868,457 shs$817.13 million07/29/2025$14.34$13.97-2.58%$14.63$12.95469,205 shs$751.45 million07/28/2025$13.63$14.34+5.21%$15.27$13.59760,548 shs$771.35 million07/25/2025$13.35$13.63+2.10%$13.97$12.74399,320 shs$733.16 million Get the Latest News and Ratings for UPB and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 07/24/2025$11.53$13.35+15.78%$13.60$11.44673,870 shs$718.10 million07/23/2025$10.75$11.53+7.26%$11.84$10.871.10 million shs$620.20 million07/22/2025$10.64$10.75+1.03%$11.15$10.54281,399 shs$578.24 million07/21/2025$10.72$10.64-0.75%$11.08$10.61198,666 shs$572.33 million07/18/2025$11.04$10.72-2.90%$11.36$10.63225,652 shs$576.63 million07/17/2025$10.92$11.04+1.10%$11.44$10.78561,208 shs$593.89 million07/16/2025$11.14$10.92-1.97%$11.54$10.78389,732 shs$587.39 million07/15/2025$11.73$11.14-5.03%$11.89$11.11161,741 shs$599.27 million07/14/2025$11.48$11.73+2.18%$12.10$11.30261,127 shs$631.00 million07/11/2025$11.84$11.48-3.04%$11.85$11.45164,986 shs$617.56 million07/10/2025$11.70$11.84+1.20%$11.97$11.53410,864 shs$636.87 million07/09/2025$10.90$11.70+7.34%$11.84$10.92527,783 shs$629.34 million07/08/2025$10.98$10.90-0.73%$11.22$10.75207,281 shs$586.36 million07/07/2025$11.20$10.98-1.96%$11.47$10.83299,778 shs$590.61 million Related Companies MLTX Stock Price Chart PTGX Stock Price Chart HCM Stock Price Chart APLS Stock Price Chart INDV Stock Price Chart MOR Stock Price Chart KYMR Stock Price Chart IMVT Stock Price Chart CRNX Stock Price Chart XENE Stock Price Chart Receive UPB Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 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