Upstream Bio (UPB) Stock Chart & Stock Price History $8.64 -0.36 (-4.00%) Closing price 04:00 PM EasternExtended Trading$8.65 +0.01 (+0.17%) As of 06:31 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock Upstream Bio Stock Price Performance 5 Day Performance+2.98%1 Month Performance+33.13%3 Month Performance-19.78%6 Month Performance-65.11%Year-To-Date Performance-47.45% Receive UPB Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. Email Address UPB Stock Chart for Friday, May, 2, 2025 UPB Chart by TradingView Upstream Bio Stock Price History Daily Weekly Monthly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year Time Frame * Start Date * End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization05/02/2025$9.00$8.64-4.00%$9.29$8.63484,378 shs$463.87 million05/01/2025$9.26$9.00-2.81%$9.49$8.75267,173 shs$483.20 million04/30/2025$8.98$9.26+3.12%$9.41$8.59189,688 shs$497.16 million04/29/2025$8.78$8.98+2.28%$9.82$8.55216,944 shs$482.13 million04/28/2025$8.39$8.78+4.65%$8.85$7.93291,529 shs$471.39 million04/25/2025$8.96$8.39-6.36%$8.86$8.20232,948 shs$450.05 million04/24/2025$8.81$8.96+1.70%$9.08$8.52227,944 shs$480.62 million04/23/2025$10.15$8.81-13.20%$10.50$8.53397,908 shs$472.58 million04/22/2025$9.71$10.15+4.53%$10.19$9.64324,849 shs$544.46 million04/21/2025$8.78$9.71+10.59%$9.99$8.58507,228 shs$520.85 million Get the Latest News and Ratings for UPB and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 04/18/2025$8.78$8.78$8.92$8.13315,158 shs$470.97 million04/17/2025$8.42$8.78+4.28%$8.92$8.13315,158 shs$470.97 million04/16/2025$7.77$8.42+8.37%$8.45$7.48289,337 shs$451.66 million04/15/2025$7.58$7.77+2.51%$8.21$7.56245,317 shs$416.79 million04/14/2025$7.37$7.58+2.85%$7.93$7.22186,367 shs$406.60 million04/11/2025$6.40$7.37+15.16%$7.39$6.32303,708 shs$395.33 million04/10/2025$6.53$6.40-1.99%$6.40$5.54314,654 shs$343.30 million04/09/2025$6.07$6.53+7.58%$6.61$5.14626,762 shs$350.28 million04/09/2025$6.07$6.53+7.58%$6.61$5.14626,762 shs$350.28 million04/08/2025$6.36$6.07-4.56%$6.52$5.44394,206 shs$325.60 million04/08/2025$6.36$6.07-4.56%$6.52$5.44394,206 shs$325.60 million04/07/2025$6.10$6.36+4.26%$6.39$5.52325,456 shs$341.16 million04/04/2025$6.30$6.10-3.17%$6.12$5.59212,237 shs$327.21 million04/03/2025$6.49$6.30-2.93%$6.72$5.84234,251 shs$337.94 million04/02/2025$6.70$6.49-3.13%$6.86$6.33203,018 shs$348.13 million04/01/2025$6.12$6.70+9.48%$6.72$5.85290,137 shs$359.40 million Related Companies ARWR Stock Price Chart CNTA Stock Price Chart GLPG Stock Price Chart ARQT Stock Price Chart TVTX Stock Price Chart AGIO Stock Price Chart HRMY Stock Price Chart EWTX Stock Price Chart IRON Stock Price Chart INDV Stock Price Chart Receive UPB Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. This page (NASDAQ:UPB) was last updated on 5/2/2025 by MarketBeat.com Staff From Our PartnersElon’s Terrifying Warning Forces Trump To Take ActionElon Musk has avoided two major financial crises before. He pulled Tesla and SpaceX back from the brink of col...American Hartford Gold | SponsoredSecret financial plot unfolding in Washington DC… [DEVELOPING]What stocks are next up to soar in 2025? I believe I’ve found the answer - and it might surprise you. 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