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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
$134.55
+0.1%		$124.42
$35.39
▼
$134.88
$8.37B0.341.17 million shs1.48 million shs
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$117.39
+2.6%		$105.16
$39.84
▼
$130.05
$9.76B1.95652,924 shs468,574 shs
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$6.24
+2.2%		$5.90
$2.57
▼
$9.75
$2.18B1.525.82 million shs13.33 million shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$58.07
-1.3%		$54.95
$29.87
▼
$65.00
$8.64B1.23984,587 shs656,559 shs
The 7 Hottest IPO Stories of 2026 Cover
The 7 Hottest IPO Stories of 2026

MarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. See which companies are preparing to go public and why investors are watching closely.

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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
0.00%-0.22%+0.35%+65.82%+260.03%
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
0.00%+9.18%+2.98%+42.79%+188.22%
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
0.00%-5.60%+10.45%+43.83%+139.81%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
0.00%0.00%+3.62%+10.84%+84.06%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
$134.55
+0.1%		$124.42
$35.39
▼
$134.88
$8.37B0.341.17 million shs1.48 million shs
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$117.39
+2.6%		$105.16
$39.84
▼
$130.05
$9.76B1.95652,924 shs468,574 shs
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$6.24
+2.2%		$5.90
$2.57
▼
$9.75
$2.18B1.525.82 million shs13.33 million shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$58.07
-1.3%		$54.95
$29.87
▼
$65.00
$8.64B1.23984,587 shs656,559 shs
The 7 Hottest IPO Stories of 2026 Cover
The 7 Hottest IPO Stories of 2026

MarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. See which companies are preparing to go public and why investors are watching closely.

Get This Free Report

Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
0.00%-0.22%+0.35%+65.82%+260.03%
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
0.00%+9.18%+2.98%+42.79%+188.22%
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
0.00%-5.60%+10.45%+43.83%+139.81%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
0.00%0.00%+3.62%+10.84%+84.06%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
2.20
Hold$124.43-7.52% Downside
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
2.83
Moderate Buy$125.657.04% Upside
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
2.64
Moderate Buy$13.00108.50% Upside
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
2.50
Moderate Buy$86.0048.10% Upside

Current Analyst Ratings Breakdown

Latest NUVB, KYMR, PCVX, and APGE Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
8/13/2026
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
Truist Financial Corporation logo
Truist Financial
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetHold$81.00 ➝ $135.00
8/12/2026
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
BTIG Research logo
BTIG Research
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
DowngradeBuy ➝ Neutral
8/12/2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
Zacks Research logo
Zacks Research
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
UpgradeStrong Sell ➝ Hold
8/7/2026
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
B. Riley Financial, Inc. logo
B. Riley Financial
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingBuy
8/7/2026
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
Royal Bank Of Canada logo
Royal Bank Of Canada
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetOutperform$19.00 ➝ $20.00
8/6/2026
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
Morgan Stanley logo
Morgan Stanley
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingOverweight$135.00
8/6/2026
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
Citigroup Inc. logo
Citigroup
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingBuy
8/6/2026
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
Barclays PLC logo
Barclays
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetOverweight$133.00 ➝ $139.00
8/5/2026
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
Oppenheimer Holdings, Inc. logo
Oppenheimer
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingOutperform$125.00
7/30/2026
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
Deutsche Bank Aktiengesellschaft logo
Deutsche Bank Aktiengesellschaft
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Initiated CoverageHold$120.00
7/28/2026
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
Guggenheim logo
Guggenheim
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetBuy$125.00 ➝ $135.00
(Data available from 8/16/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
N/AN/AN/AN/A$19.21 per shareN/A
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$39.21M248.94N/AN/A$18.15 per share6.47
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$62.90M34.80N/AN/A$0.72 per share8.66
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/A$18.53 per shareN/A
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
-$255.84M-$4.34N/AN/AN/AN/A-29.88%-28.08%N/A
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
-$311.35M-$3.24N/AN/AN/A-285.33%-21.22%-19.21%11/3/2026 (Estimated)
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
-$204.63M-$0.44N/AN/AN/A-88.18%-46.59%-22.01%11/2/2026 (Estimated)
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$766.63M-$7.63N/AN/AN/AN/A-37.56%-33.62%11/3/2026 (Estimated)

Latest NUVB, KYMR, PCVX, and APGE Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
8/10/2026Q2 2026
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
-$1.07-$1.14-$0.07-$1.14$10.00 millionN/A
8/6/2026Q2 2026
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
-$0.1417-$0.15-$0.0083-$0.18$27.03 million$31.69 million
8/5/2026Q2 2026
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
-$0.7126-$0.62+$0.0926-$0.62$32.78 million$65.00 million
8/5/2026Q2 2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$2.06-$1.97+$0.09-$1.97$12.50 millionN/A
CompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive Growth
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
N/AN/AN/AN/AN/A
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
N/AN/AN/AN/AN/A
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
N/AN/AN/AN/AN/A
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
N/A
26.44
32.59
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
N/A
10.34
10.34
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
0.96
8.37
8.14
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/A
5.72
5.72

Institutional Ownership

CompanyInstitutional Ownership
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
79.04%
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
N/A
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
61.67%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
96.78%

Insider Ownership

CompanyInsider Ownership
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
24.30%
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
15.98%
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
30.11%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
3.30%
CompanyEmployeesShares OutstandingFree FloatOptionable
Apogee Therapeutics Inc. stock logo
APGE
Apogee Therapeutics
9162.20 million47.09 millionOptionable
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
17083.15 million69.86 millionOptionable
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
60351.12 million245.40 millionOptionable
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
160148.80 million143.89 millionOptionable

Recent News About These Companies

If You Followed Seth Klarman Into Vaxcyte in May, He Was Already Long Gone
 |  247wallst.comhttps://247wallst.com/investing/2026/08/16/if-you-followed-seth-klarman-into-vaxcyte-in-may-he-was-already-long-gone/?utm_source=snapi
Vaxcyte (NASDAQ:PCVX) Stock Rating Upgraded by Zacks Research
August 14 at 5:59 AM  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/vaxcyte-nasdaqpcvx-stock-rating-upgraded-by-zacks-research-2026-08-14/
Assenagon Asset Management S.A. Decreases Stock Holdings in Vaxcyte, Inc. $PCVX
August 12, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/filing-assenagon-asset-management-sa-decreases-stock-holdings-in-vaxcyte-inc-pcvx-2026-08-12/
Bank of America Corp DE Increases Position in Vaxcyte, Inc. $PCVX
August 10, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/filing-bank-of-america-corp-de-increases-position-in-vaxcyte-inc-pcvx-2026-08-10/
Vaxcyte (NASDAQ:PCVX) Upgraded to "Sell" at Wall Street Zen
August 8, 2026  |  americanbankingnews.comhttps://www.americanbankingnews.com/?p=30947826
Vaxcyte (NASDAQ:PCVX) Stock Rating Upgraded by Wall Street Zen
August 8, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/vaxcyte-nasdaqpcvx-stock-rating-upgraded-by-wall-street-zen-2026-08-08/
Analysts Offer Insights on Healthcare Companies: Vaxcyte (PCVX), Black Diamond Therapeutics (BDTX) and Sarepta Therapeutics (SRPT)
August 7, 2026  |  theglobeandmail.comhttps://www.theglobeandmail.com/investing/markets/stocks/PCVX/pressreleases/3714550/analysts-offer-insights-on-healthcare-companies-vaxcyte-pcvx-black-diamond-therapeutics-bdtx-and-sarepta-therapeutics-srpt/
Vaxcyte (PCVX) Receives a Buy from Guggenheim
August 7, 2026  |  theglobeandmail.comhttps://www.theglobeandmail.com/investing/markets/stocks/PCVX/pressreleases/3715307/vaxcyte-pcvx-receives-a-buy-from-guggenheim/
The Manufacturers Life Insurance Company Trims Stock Position in Vaxcyte, Inc. $PCVX
August 7, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/filing-the-manufacturers-life-insurance-company-trims-stock-position-in-vaxcyte-inc-pcvx-2026-08-07/
Vaxcyte, Inc. $PCVX Shares Acquired by Dimensional Fund Advisors LP
August 7, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/filing-vaxcyte-inc-pcvx-shares-acquired-by-dimensional-fund-advisors-lp-2026-08-07/
Insider Selling: Vaxcyte (NASDAQ:PCVX) COO Sells 2,250 Shares
August 6, 2026  |  insidertrades.comhttps://www.insidertrades.com/alerts/nasdaq-pcvx-insider-buying-and-selling-2026-08-06/
Vaxcyte (NASDAQ:PCVX) Releases Quarterly Earnings Results, Beats Expectations By $0.09 EPS
August 5, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/vaxcyte-nasdaqpcvx-releases-quarterly-earnings-results-beats-expectations-by-009-eps-2026-08-05/
Vaxcyte (NASDAQ:PCVX) Insider Harpreet Dhaliwal Sells 17,000 Shares
August 5, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/vaxcyte-nasdaqpcvx-insider-harpreet-dhaliwal-sells-17000-shares-2026-08-05/
Insider Selling: Vaxcyte (NASDAQ:PCVX) COO Sells 2,250 Shares of Stock
August 5, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/insider-selling-vaxcyte-nasdaqpcvx-coo-sells-2250-shares-of-stock-2026-08-05/
Vaxcyte (NASDAQ:PCVX) CFO Andrew Guggenhime Sells 10,000 Shares of Stock
August 5, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/vaxcyte-nasdaqpcvx-cfo-andrew-guggenhime-sells-10000-shares-of-stock-2026-08-05/
Vaxcyte Reports Second Quarter 2026 Financial Results and Provides Business Update
August 5, 2026  |  globenewswire.comhttps://www.globenewswire.com/news-release/2026/08/05/3339693/0/en/vaxcyte-reports-second-quarter-2026-financial-results-and-provides-business-update.html
California State Teachers Retirement System Has $7.91 Million Holdings in Vaxcyte, Inc. $PCVX
August 5, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/filing-california-state-teachers-retirement-system-has-791-million-holdings-in-vaxcyte-inc-pcvx-2026-08-05/
Vaxcyte, Inc. (NASDAQ:PCVX) Receives Consensus Recommendation of "Hold" from Analysts
August 4, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/vaxcyte-inc-nasdaqpcvx-receives-consensus-recommendation-of-hold-from-analysts-2026-08-04/
Seven Fleet Capital Management LP Buys 103,085 Shares of Vaxcyte, Inc. $PCVX
August 2, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/filing-seven-fleet-capital-management-lp-buys-103085-shares-of-vaxcyte-inc-pcvx-2026-08-02/
DV Trading LLC Takes Position in Vaxcyte, Inc. $PCVX
August 2, 2026  |  marketbeat.comhttps://www.marketbeat.com/instant-alerts/filing-dv-trading-llc-takes-position-in-vaxcyte-inc-pcvx-2026-08-02/
Analysts Offer Insights on Healthcare Companies: GE Healthcare Technologies Inc (GEHC), Biogen (BIIB) and Vaxcyte (PCVX)
July 31, 2026  |  theglobeandmail.comhttps://www.theglobeandmail.com/investing/markets/stocks/BIIB-Q/pressreleases/3572153/analysts-offer-insights-on-healthcare-companies-ge-healthcare-technologies-inc-gehc-biogen-biib-and-vaxcyte-pcvx/

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Media Sentiment Over Time

Apogee Therapeutics stock logo

Apogee Therapeutics NASDAQ:APGE

$134.55 +0.10 (+0.07%)
Closing price 08/14/2026 04:00 PM Eastern
Extended Trading
$134.57 +0.02 (+0.01%)
As of 08/14/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Apogee Therapeutics, Inc., through its subsidiary, operates as a biotechnology company that develops biologics for the treatment of atopic dermatitis (AD), asthma, chronic obstructive pulmonary disease (COPD), and related inflammatory and immunology indications. The company primarily develops APG777, a subcutaneous (SQ) extended half-life monoclonal antibody (mAb) for AD; and APG808, an SQ extended half-life mAb for COPD. Its earlier-stage programs comprise APG990, an SQ extended half-life mAb for the treatment of AD; and APG222, an extended half-life SQ antibodies for AD. Apogee Therapeutics, Inc. was incorporated in 2022 and is headquartered in Waltham, Massachusetts.

Kymera Therapeutics stock logo

Kymera Therapeutics NASDAQ:KYMR

$117.39 +2.97 (+2.60%)
Closing price 08/14/2026 04:00 PM Eastern
Extended Trading
$117.35 -0.04 (-0.04%)
As of 08/14/2026 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Kymera Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. It engages in developing IRAK4 program, which is in Phase II clinical trial for the treatment of immunology-inflammation diseases, including hidradenitis suppurativa, atopic dermatitis; STAT3 program for the treatment of hematologic malignancies and solid tumors, as well as autoimmune diseases and fibrosis; and MDM2 program to treat hematological malignancies and solid tumors. The company develops STAT6, a Type 2 inflammation in allergic diseases; and TYK2, a treatment for inflammatory bowel disease, psoriasis, psoriatic arthritis, and lupus. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.

Nuvation Bio stock logo

Nuvation Bio NYSE:NUVB

$6.24 +0.14 (+2.21%)
Closing price 08/14/2026 03:59 PM Eastern
Extended Trading
$6.11 -0.13 (-2.00%)
As of 08/14/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutic candidates for oncology. The company's lead product candidate is NUV-868, a BD2 selective oral small molecule BET inhibitor that epigenetically regulates proteins that control tumor growth and differentiation, including oncogenes comprising c-myc; NUV-1156, an AR binder Xtandi that address advanced stage prostate cancers with the potential to move into earlier lines typically treated with surgical prostatectomy; and drug-drug conjugate (DDC) platform which leverages a novel therapeutic approach within the drug-conjugate class of anti-cancer therapies to deliver anti-cancer therapeutics to cancer cells, as well as NUV-1176, a PARP inhibitor to address ER+ breast and ovarian cancer. The company was founded in 2018 and is headquartered in New York, New York.

Vaxcyte stock logo

Vaxcyte NASDAQ:PCVX

$58.07 -0.79 (-1.34%)
Closing price 08/14/2026 04:00 PM Eastern
Extended Trading
$58.07 0.00 (0.00%)
As of 08/14/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Vaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease. The company also develops VAX-31 to protect against emerging strains and to help address antibiotic resistance; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis; and VAX-GI to prevent Shigella, a bacterial illness. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.

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