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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
$14.25
-6.8%
$20.49
$14.00
▼
$27.31
$2.66B1.123.29 million shs2.86 million shs
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
$9.18
-8.2%
$8.57
$1.95
▼
$12.43
$9.73B0.0215.89 million shs21.48 million shs
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$449.74
-2.2%
$515.06
$393.61
▼
$615.00
$10.39B-1.04283,726 shs364,533 shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$63.62
-2.5%
$61.14
$39.87
▼
$90.75
$9.47B1.233.60 million shs3.25 million shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
0.00%-14.36%-21.10%-39.97%-13.79%
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
0.00%-12.65%+8.51%+19.53%+255.81%
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
0.00%-4.67%-15.84%-18.74%+3.76%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
0.00%-10.87%+5.38%+13.20%+44.79%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
$14.25
-6.8%
$20.49
$14.00
▼
$27.31
$2.66B1.123.29 million shs2.86 million shs
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
$9.18
-8.2%
$8.57
$1.95
▼
$12.43
$9.73B0.0215.89 million shs21.48 million shs
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$449.74
-2.2%
$515.06
$393.61
▼
$615.00
$10.39B-1.04283,726 shs364,533 shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$63.62
-2.5%
$61.14
$39.87
▼
$90.75
$9.47B1.233.60 million shs3.25 million shs
The 7 Hottest IPO Stories of 2026 Cover

MarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. See which companies are preparing to go public and why investors are watching closely.

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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
0.00%-14.36%-21.10%-39.97%-13.79%
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
0.00%-12.65%+8.51%+19.53%+255.81%
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
0.00%-4.67%-15.84%-18.74%+3.76%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
0.00%-10.87%+5.38%+13.20%+44.79%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
2.75
Moderate Buy$33.07132.08% Upside
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
2.71
Moderate Buy$16.0074.29% Upside
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
2.78
Moderate Buy$699.2055.47% Upside
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
2.67
Moderate Buy$110.5073.69% Upside

Current Analyst Ratings Breakdown

Latest DYN, IBRX, MDGL, and PCVX Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
10/15/2026
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
Reiterated RatingSell (D-)
10/15/2026
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
Reiterated RatingSell (D-)
10/15/2026
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
Reiterated RatingBuy$15.00
10/14/2026
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
Boost Price TargetBuy$12.00 ➝ $14.00
10/14/2026
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
Reiterated RatingOverweight$16.00
10/14/2026
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
Reiterated RatingBuy$735.00
10/12/2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
Reiterated RatingOverweight$120.00
10/6/2026
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
Reiterated RatingSell (D-)
10/5/2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
Boost Price TargetBuy$116.00 ➝ $125.00
10/5/2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
Reiterated RatingBuy$89.00
10/5/2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
Boost Price TargetBuy$110.00 ➝ $122.00
(Data available from 10/18/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
N/AN/AN/AN/A$6.81 per shareN/A
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
$113.29M85.88N/AN/A($0.51) per share-18.00
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$1.28B8.09N/AN/A$26.54 per share16.95
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/A$20.51 per shareN/A
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
-$446.21M-$3.33N/AN/AN/AN/A-64.30%-50.33%11/4/2026 (Estimated)
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
-$351.40M-$0.97N/AN/AN/A-598.55%N/A-51.65%11/3/2026 (Estimated)
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
-$288.28M-$12.89N/A83.59N/A-25.32%-56.65%-25.53%11/3/2026 (Estimated)
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$766.63M-$7.63N/AN/AN/AN/A-37.56%-33.62%11/3/2026 (Estimated)

Latest DYN, IBRX, MDGL, and PCVX Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
11/4/2026Q3 2026
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
-$0.9122N/AN/AN/AN/AN/A
11/3/2026Q3 2026
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
-$0.07N/AN/AN/A$59.23 millionN/A
11/3/2026Q3 2026
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
-$0.8345N/AN/AN/A$405.27 millionN/A
11/3/2026Q3 2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$2.11N/AN/AN/A$12.50 millionN/A
8/5/2026Q2 2026
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$2.06-$1.97+$0.09-$1.97$12.50 millionN/A
8/4/2026Q2 2026
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
-$0.08-$0.22-$0.14-$0.22$49.70 million$51.24 million
7/30/2026Q2 2026
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
-$2.68-$1.99+$0.69-$1.99$352.13 million$364.25 million
7/29/2026Q2 2026
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
-$0.7488-$1.08-$0.3312-$1.08N/AN/A
CompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive Growth
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
N/AN/AN/AN/AN/A
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
N/AN/AN/AN/AN/A
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
N/AN/AN/AN/AN/A
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
0.28
12.02
12.02
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
N/A
5.72
5.70
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
0.65
3.20
2.94
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/A
5.72
5.72

Institutional Ownership

CompanyInstitutional Ownership
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
96.68%
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
8.58%
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
98.50%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
96.78%

Insider Ownership

CompanyInsider Ownership
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
9.46%
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
66.10%
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
17.60%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
3.30%
CompanyEmployeesShares OutstandingFree FloatOptionable
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
258186.75 million169.08 millionOptionable
ImmunityBio, Inc. stock logo
IBRX
ImmunityBio
6911.06 billion359.28 millionOptionable
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
91523.10 million19.04 millionOptionable
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
507148.81 million143.89 millionOptionable

Recent News About These Companies

Cantor Fitzgerald sets USD 120.00 target for Vaxcyte stock
Vaxcyte stock rises 6.82 percent to EUR 58.75 after-hours
Leerink Partners Reaffirms Their Buy Rating on Vaxcyte (PCVX)
Vaxcyte (NASDAQ: PCVX) raises $575 million with notes and stock sale
Vaxcyte (NASDAQ:PCVX) Stock Jumps 8.7% - What's Next?
Vaxcyte (NASDAQ:PCVX) Stock: Insider Jim Wassil Sells 18,000 Shares
Why Vaxcyte (PCVX) Is Getting Attention Again
Vaxcyte (NASDAQ:PCVX) EVP Sells $1,561,320.00 in Stock

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

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Dyne Therapeutics stock logo

Dyne Therapeutics NASDAQ:DYN

$14.25 -1.04 (-6.80%)
Closing price 10/16/2026 04:00 PM Eastern
Extended Trading
$14.40 +0.15 (+1.02%)
As of 10/16/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Dyne Therapeutics, Inc., a clinical-stage muscle disease company, operates as a biotechnology company that focuses on advancing therapeutics for genetically driven muscle diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; and facioscapulohumeral dystrophy, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. Dyne Therapeutics, Inc. was incorporated in 2017 and is headquartered in Waltham, Massachusetts.

ImmunityBio stock logo

ImmunityBio NASDAQ:IBRX

$9.18 -0.82 (-8.20%)
Closing price 10/16/2026 04:00 PM Eastern
Extended Trading
$9.20 +0.02 (+0.17%)
As of 10/16/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

ImmunityBio, Inc., a clinical-stage biotechnology company, engages in developing therapies and vaccines that bolster the natural immune system to defeat cancers and infectious diseases. Its platforms for the development of biologic product candidates include antibody-cytokine fusion proteins; DNA, RNA, and recombinant protein vaccines; and cell therapies. The company's platforms have generated therapeutic agents that are currently being or planned to be studied in clinical trials across various indications in liquid and solid tumors, including bladder, lung and colorectal cancers, and glioblastoma multiforme. Its lead biologic product candidate is Anktiva, an FDA-approved immunotherapy in combination with bacillus calmette-guérin (BCG) for the treatment of adult patients with BCG unresponsive non-muscle invasive bladder cancer with carcinoma in situ, with or without papillary tumors. The company has collaboration agreements with National Cancer Institute. It also has license agreements with 3M Innovative Properties Company; Access to Advanced Health Institute; LadRx Corporation; Sanford Health; Shenzhen Beike Biotechnology Co. Ltd.; Viracta Therapeutics, Inc.; and GlobeImmune, Inc. The company is based in San Diego, California.

Madrigal Pharmaceuticals stock logo

Madrigal Pharmaceuticals NASDAQ:MDGL

$449.74 -10.07 (-2.19%)
Closing price 10/16/2026 04:00 PM Eastern
Extended Trading
$449.75 +0.01 (+0.00%)
As of 10/16/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutics for the treatment of non-alcoholic steatohepatitis (NASH) in the United States. Its lead product candidate is resmetirom, a liver-directed thyroid hormone receptor beta agonist, which is in Phase 3 clinical trials for treating NASH. The company is headquartered in West Conshohocken, Pennsylvania.

Vaxcyte stock logo

Vaxcyte NASDAQ:PCVX

$63.62 -1.65 (-2.53%)
Closing price 10/16/2026 04:00 PM Eastern
Extended Trading
$62.86 -0.77 (-1.20%)
As of 10/16/2026 07:55 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Vaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease. The company also develops VAX-31 to protect against emerging strains and to help address antibiotic resistance; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis; and VAX-GI to prevent Shigella, a bacterial illness. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.