Spero Therapeutics (SPRO) Stock Chart & Stock Price History $2.90 0.00 (0.00%) Closing price 07/2/2025 04:00 PM EasternExtended Trading$2.91 +0.01 (+0.34%) As of 04:02 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Spero Therapeutics Stock Price Performance The Spero Therapeutics (SPRO) stock chart highlights key performance trends across multiple timeframes. Over the last 12 months, the stock's price has increased 118.87%, with a year-to-date return of 181.55%. In the past month, the stock has increased 9.85%, reflecting recent market activity. As of the latest close, Spero Therapeutics traded at $2.90 with a market cap of $162.14 million and volume of 1.10 million shares. Five years ago, the stock traded at $13.37, representing a 78.31% decrease over that period. At the time, it had a market cap of $271.58 million and a volume of 94,827 shares. Receive SPRO Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spero Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address 5 Day Performance-1.36%1 Month Performance+9.85%3 Month Performance+364.74%Year-To-Date Performance+181.55%1 Year Performance+118.87%5 Year Performance-78.31% SPRO Stock Chart for Thursday, July, 3, 2025 SPRO Chart by TradingView Spero Therapeutics Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame Start Date End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization07/02/2025$2.90$2.90$3.03$2.901.10 million shs$162.14 million07/01/2025$2.90$2.90$2.95$2.90639,760 shs$162.14 million06/30/2025$2.94$2.90-1.36%$3.00$2.901.15 million shs$162.14 million06/27/2025$2.90$2.94+1.38%$3.09$2.901.69 million shs$164.38 million06/26/2025$2.90$2.90$2.94$2.87557,949 shs$162.14 million06/25/2025$2.88$2.90+0.69%$2.93$2.791.46 million shs$162.14 million06/24/2025$2.93$2.88-1.71%$2.97$2.811.01 million shs$161.02 million06/23/2025$3.02$2.93-2.98%$3.00$2.88860,877 shs$163.82 million06/20/2025$2.94$3.02+2.72%$3.02$2.872.11 million shs$168.85 million06/19/2025$2.94$2.94$2.98$2.861.84 million shs$164.38 million Get the Latest News and Ratings for SPRO and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spero Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 06/18/2025$2.90$2.94+1.38%$2.98$2.861.84 million shs$164.38 million06/17/2025$2.85$2.90+1.75%$2.95$2.812.09 million shs$162.14 million06/16/2025$2.83$2.85+0.71%$2.95$2.831.11 million shs$159.35 million06/13/2025$2.89$2.83-2.08%$2.86$2.772.07 million shs$158.23 million06/12/2025$2.80$2.89+3.21%$3.06$2.712.12 million shs$161.58 million06/11/2025$2.85$2.80-1.75%$2.89$2.641.89 million shs$156.55 million06/10/2025$2.76$2.85+3.26%$2.93$2.722.22 million shs$159.35 million06/09/2025$2.50$2.76+10.40%$2.81$2.503.99 million shs$154.31 million06/06/2025$2.56$2.50-2.34%$2.74$2.452.55 million shs$139.78 million06/05/2025$2.66$2.56-3.76%$2.69$2.521.70 million shs$143.13 million06/04/2025$2.64$2.66+0.76%$2.90$2.472.65 million shs$148.72 million06/03/2025$2.74$2.64-3.65%$2.78$2.552.10 million shs$147.61 million06/02/2025$2.58$2.74+6.20%$2.95$2.426.58 million shs$153.20 million Related Companies Nuvation Bio Stock Price Chart Iovance Biotherapeutics Stock Price Chart Arbutus Biopharma Stock Price Chart Day One Biopharmaceuticals Stock Price Chart GH Research Stock Price Chart Sionna Therapeutics Stock Price Chart Stoke Therapeutics Stock Price Chart ChromaDex Stock Price Chart Xencor Stock Price Chart KalVista Pharmaceuticals Stock Price Chart Receive SPRO Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spero Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 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