Spyre Therapeutics (SYRE) Stock Chart & Stock Price History $15.11 +0.45 (+3.07%) Closing price 05/2/2025 04:00 PM EasternExtended Trading$14.97 -0.14 (-0.93%) As of 05/2/2025 04:24 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Spyre Therapeutics Stock Price Performance 5 Day Performance+3.00%1 Month Performance+8.01%3 Month Performance-34.02%6 Month Performance-55.53%Year-To-Date Performance-35.09%1 Year Performance-57.77% Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address SYRE Stock Chart for Saturday, May, 3, 2025 SYRE Chart by TradingView Spyre Therapeutics Stock Price History Daily Weekly Monthly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year Time Frame * Start Date * End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization05/02/2025$14.66$15.11+3.07%$15.63$14.66499,924 shs$910.77 million05/01/2025$15.23$14.66-3.74%$15.77$14.48451,684 shs$883.65 million04/30/2025$15.02$15.23+1.40%$15.45$14.64439,457 shs$918.00 million04/29/2025$14.67$15.02+2.39%$15.18$14.30355,834 shs$905.35 million04/28/2025$14.13$14.67+3.82%$14.91$14.16550,929 shs$884.25 million04/25/2025$14.93$14.13-5.36%$14.80$13.83387,940 shs$851.70 million04/24/2025$14.22$14.93+4.99%$14.99$14.071.00 million shs$899.92 million04/23/2025$13.96$14.22+1.86%$14.79$14.11618,304 shs$857.13 million04/22/2025$13.57$13.96+2.87%$14.04$13.06500,512 shs$841.45 million04/21/2025$12.67$13.57+7.10%$13.81$12.53740,392 shs$817.95 million Get the Latest News and Ratings for SYRE and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 04/18/2025$12.67$12.67$12.79$12.25740,114 shs$763.46 million04/17/2025$12.42$12.67+2.01%$12.79$12.25740,114 shs$763.46 million04/16/2025$12.71$12.42-2.28%$13.25$12.04573,432 shs$748.39 million04/15/2025$13.02$12.71-2.38%$13.29$12.57530,809 shs$765.87 million04/14/2025$12.22$13.02+6.55%$13.10$12.361.00 million shs$784.55 million04/11/2025$11.93$12.22+2.43%$12.87$11.50599,414 shs$736.34 million04/10/2025$13.37$11.93-10.77%$12.95$11.62978,765 shs$718.87 million04/09/2025$11.80$13.37+13.31%$13.76$10.911.03 million shs$805.64 million04/09/2025$11.80$13.37+13.31%$13.76$10.911.03 million shs$805.64 million04/08/2025$12.39$11.80-4.76%$13.28$11.461.52 million shs$711.03 million04/08/2025$12.39$11.80-4.76%$13.28$11.461.52 million shs$711.03 million04/07/2025$12.79$12.39-3.13%$13.23$11.601.28 million shs$746.58 million04/04/2025$13.99$12.79-8.58%$13.63$12.561.64 million shs$770.69 million04/03/2025$15.49$13.99-9.68%$15.02$13.88973,063 shs$843.00 million04/02/2025$15.30$15.49+1.24%$15.80$14.90586,262 shs$933.38 million Related Companies SWTX Stock Chart OGN Stock Chart MRUS Stock Chart CRNX Stock Chart SRRK Stock Chart AKRO Stock Chart VKTX Stock Chart XENE Stock Chart CPRX Stock Chart MOR Stock Chart Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 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