Spyre Therapeutics (SYRE) Stock Chart & Stock Price History $15.01 -0.06 (-0.40%) Closing price 04:00 PM EasternExtended Trading$15.01 0.00 (0.00%) As of 04:20 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Spyre Therapeutics Stock Price Performance The Spyre Therapeutics (SYRE) stock chart highlights key performance trends across multiple timeframes. Over the last 12 months, the stock's price has decreased 54.07%, with a year-to-date return of -35.52%. In the past month, the stock has increased 5.56%, reflecting recent market activity. As of the latest close, Spyre Therapeutics traded at $15.07 with a market cap of $908.36 million and volume of 358,047 shares. Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address 5 Day Performance-1.12%1 Month Performance+5.56%3 Month Performance-29.50%Year-To-Date Performance-35.52%1 Year Performance-54.07% SYRE Stock Chart for Friday, May, 23, 2025 SYRE Chart by TradingView Spyre Therapeutics Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame * Start Date * End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization05/22/2025$14.78$15.07+1.96%$15.18$14.59358,047 shs$908.36 million05/21/2025$15.40$14.78-4.03%$15.45$14.65274,429 shs$890.88 million05/20/2025$14.88$15.40+3.49%$15.45$14.73297,273 shs$928.25 million05/19/2025$15.18$14.88-1.98%$15.55$14.61338,924 shs$896.91 million05/16/2025$14.54$15.18+4.40%$15.37$14.39340,714 shs$914.99 million05/15/2025$14.80$14.54-1.76%$14.86$14.12452,521 shs$876.41 million05/14/2025$14.75$14.80+0.34%$14.99$14.26907,797 shs$892.09 million05/13/2025$14.93$14.75-1.21%$14.96$14.131.03 million shs$889.07 million05/12/2025$14.10$14.93+5.89%$15.57$14.76663,378 shs$899.92 million05/09/2025$12.87$14.10+9.57%$14.80$12.95966,118 shs$849.89 million Get the Latest News and Ratings for SYRE and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 05/08/2025$12.71$12.87+1.25%$13.41$12.29322,536 shs$775.69 million05/07/2025$12.51$12.71+1.60%$12.92$12.33418,704 shs$766.11 million05/06/2025$14.09$12.51-11.21%$14.28$12.49483,362 shs$754.05 million05/05/2025$15.11$14.09-6.75%$15.10$13.93375,308 shs$849.29 million05/02/2025$14.66$15.11+3.07%$15.63$14.66499,924 shs$910.77 million05/01/2025$15.23$14.66-3.74%$15.77$14.48451,684 shs$883.65 million04/30/2025$15.02$15.23+1.40%$15.45$14.64439,457 shs$918.00 million04/29/2025$14.67$15.02+2.39%$15.18$14.30355,834 shs$905.35 million04/28/2025$14.13$14.67+3.82%$14.91$14.16550,929 shs$884.25 million04/25/2025$14.93$14.13-5.36%$14.80$13.83387,940 shs$851.70 million04/24/2025$14.22$14.93+4.99%$14.99$14.071.00 million shs$899.92 million04/23/2025$13.96$14.22+1.86%$14.79$14.11618,304 shs$857.13 million04/22/2025$13.57$13.96+2.87%$14.04$13.06500,512 shs$841.45 million Related Companies SRPT Stock Chart RNA Stock Chart SWTX Stock Chart RARE Stock Chart AKRO Stock Chart ACLX Stock Chart ZLAB Stock Chart VKTX Stock Chart CRNX Stock Chart ALVO Stock Chart Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. This page (NASDAQ:SYRE) was last updated on 5/23/2025 by MarketBeat.com Staff From Our PartnersWhite House to reset Social Security?Elon Musk's parting DOGE gift looks set to shock America... A single announcement by July 22nd could soon b...Altimetry | SponsoredJuly 2025 Rule Change to Impact Retirement InvestorsThere's a massive change from a new rule going into effect this July. And it's one the Big Banks are alread...Premier Gold Co | SponsoredThis Signal Only Flashes Once Every 4 Years – And It Just TriggeredThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredElon Set to Shock the World on June 1st?Tech legend Jeff Brown recently traveled to the industrial zone of South Memphis to investigate what he believ...Brownstone Research | SponsoredMassive new energy source found in UtahNEW THIS WEEK: Huge Energy Discovery In Utah The Department of Energy say it could power America for millio...Stansberry Research | SponsoredWhy Elon put $51 million into thisWhy Elon Musk Just Invested $51 Million Into Brand New “Miracle Metal” Developed by MIT ScientistsTrue Market Insiders | Sponsored3..2..1.. AI 2.0 ignition (don’t sleep on this)I just put together an urgent new presentation that you need to see right away. In short: I believe we are...Timothy Sykes | SponsoredNow I look stupid. Real stupid... I thought what happened 25 years ago was a once- in-a-lifetime event… but how wrong I was. Because here we...Porter & Company | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added five stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding Spyre Therapeutics, Inc. Please log in to your account or sign up in order to add this asset to your watchlist. Share Spyre Therapeutics With A Colleague Link copied to clipboard. Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Buy SYRE Stock Free SYRE Stock Alerts