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Vertex Pharmaceuticals (VRTX) Stock Forecast & Price Target

Vertex Pharmaceuticals logo
$425.09 -13.31 (-3.04%)
Closing price 04:00 PM Eastern
Extended Trading
$431.76 +6.67 (+1.57%)
As of 07:17 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Vertex Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2026)

Consensus Rating

Sell
0
Hold
3
Buy
22

Based on 25 Wall Street analysts who have issued ratings for Vertex Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 25 analysts, 3 have given a hold rating, and 22 have given a buy rating for VRTX.

Consensus Price Target

$555.91
30.78% Upside
According to the 25 analysts' twelve-month price targets for Vertex Pharmaceuticals, the average price target is $555.91. The highest price target for VRTX is $641.00, while the lowest price target for VRTX is $436.00. The average price target represents a forecasted upside of 30.78% from the current price of $425.09.
MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.
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VRTX Analyst Ratings Over Time

TypeCurrent Forecast
6/2/25 to 6/2/26
1 Month Ago
5/3/25 to 5/3/26
3 Months Ago
3/4/25 to 3/4/26
1 Year Ago
6/2/24 to 6/2/25
Strong Buy
0 Strong Buy rating(s)
1 Strong Buy rating(s)
0 Strong Buy rating(s)
1 Strong Buy rating(s)
Buy
22 Buy rating(s)
22 Buy rating(s)
22 Buy rating(s)
15 Buy rating(s)
Hold
3 Hold rating(s)
6 Hold rating(s)
5 Hold rating(s)
13 Hold rating(s)
Sell
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
Consensus Price Target$555.91$554.83$542.00$515.04
Forecasted Upside30.78% Upside30.88% Upside13.42% Upside15.63% Upside
Consensus RatingModerate BuyModerate BuyModerate BuyModerate Buy

VRTX Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.
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VRTX Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.
Skip Chart and View Analyst Price Target HistorySkip Chart & View Price History Table

Vertex Pharmaceuticals Stock vs. The Competition

TypeVertex PharmaceuticalsMedical CompaniesBroader Market
Consensus Rating Score
2.88
2.30
2.52
Consensus RatingModerate BuyHoldModerate Buy
Predicted Upside30.78% Upside1,752.07% Upside15.37% Upside
News Sentiment Rating
Positive News

See Recent VRTX News
Positive News
Positive News
DateBrokerageAnalystActionRatingPrice TargetReport Date
Upside/Downside
Details
5/27/2026
Truist Financial Corporation logo
Truist Financial
3 of 5 stars
 Initiated CoverageBuy$542.00+23.08%
5/18/2026 UpgradeHold (C+)Buy (B-)
5/6/2026
Barclays PLC logo
Barclays
3 of 5 stars
Eliana Merle
Not Rated
Boost TargetOverweight$607.00 ➝ $615.00+44.92%
5/5/2026Boost TargetOverweight$612.00 ➝ $616.00+47.34%
5/5/2026Boost TargetOutperform$541.00 ➝ $543.00+26.32%
5/5/2026Lower TargetOutperform$577.00 ➝ $572.00+33.07%
5/5/2026Lower TargetHold$437.00 ➝ $436.00+1.43%
3/18/2026UpgradeHoldBuy$575.00+24.33%
3/10/2026Boost TargetBuy$571.00 ➝ $598.00+18.47%
3/10/2026Boost TargetBuy$575.00 ➝ $585.00+16.38%
3/10/2026Initiated CoverageBuy$580.00+25.85%
3/10/2026Boost TargetOutperform$540.00 ➝ $600.00+30.19%
3/10/2026Boost TargetBuy$591.00 ➝ $641.00+39.08%
2/13/2026Boost TargetOutperform$495.00 ➝ $558.00+12.34%
2/13/2026 Reiterated RatingOverweight$590.00+20.98%
2/13/2026Boost TargetHold$445.00 ➝ $466.00+0.21%
1/26/2026Boost TargetBuy$535.00 ➝ $545.00+15.02%
1/23/2026Boost TargetOutperform$475.00 ➝ $530.00+13.41%
1/6/2026UpgradePeer PerformOutperform$548.00+22.10%
12/29/2025Boost TargetOutperform$456.00 ➝ $525.00+13.42%
12/10/2025Boost TargetOverweight$460.00 ➝ $515.00+15.74%
10/8/2025Boost TargetOverweight$517.00 ➝ $530.00+26.34%
9/2/2025Initiated CoverageMarket Perform
8/6/2025Lower TargetBuy$558.00 ➝ $546.00+40.91%
8/5/2025Set TargetOutperform$557.00 ➝ $530.00+12.22%
5/23/2025DowngradeStrong-BuyHold
5/6/2025 Reiterated RatingBuy
5/6/2025 Reiterated RatingOutperform
5/6/2025Reiterated RatingHold
1/27/2025Lower TargetOverweight$535.00 ➝ $533.00+20.72%
7/23/2024 Boost TargetBuy$450.00 ➝ $500.00+1.60%
6/27/2024Initiated CoverageBuy$545.00+14.98%
6/17/2024 Boost TargetBuy$465.00 ➝ $550.00+15.48%

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Tuesday at 07:18 PM ET.


Should I Buy Vertex Pharmaceuticals Stock? VRTX Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Friday, May 29, 2026. Please send any questions or comments about these Vertex Pharmaceuticals pros and cons to contact@marketbeat.com.

Vertex Pharmaceuticals
Bull Case

green Wall Street bull icon

Here are some ways that investors could benefit from investing in Vertex Pharmaceuticals Incorporated:

  • The current stock price is around $486, reflecting strong market interest and potential for growth.
  • Vertex Pharmaceuticals Incorporated has received multiple "buy" ratings from analysts, indicating confidence in its future performance.
  • The company is recognized for its innovative therapies in cystic fibrosis, which have significantly improved treatment standards, showcasing its commitment to research-driven drug development.
  • Recent upgrades in price targets by major brokerages suggest a positive outlook for the stock, with some analysts projecting targets above $600.
  • Insider ownership, although small at 0.20%, can indicate management's confidence in the company's future, as insiders often have a vested interest in the company's success.

Vertex Pharmaceuticals
Bear Case

red Wall Street bear icon

Investors should be bearish about investing in Vertex Pharmaceuticals Incorporated for these reasons:

  • Insider selling activity has been noted, with executives reducing their positions, which may raise concerns about the company's short-term prospects.
  • The stock has experienced fluctuations, and recent sales by executives could indicate potential volatility ahead.
  • Despite positive ratings, the consensus price target is lower than some recent highs, suggesting that the stock may face resistance in achieving higher valuations.
  • Insider ownership is relatively low, which may imply less alignment between management and shareholder interests.
  • Market conditions can be unpredictable, and the biotechnology sector often faces regulatory challenges that could impact Vertex Pharmaceuticals Incorporated's operations and stock performance.

VRTX Forecast - Frequently Asked Questions

According to the research reports of 25 Wall Street equities research analysts, the average twelve-month stock price forecast for Vertex Pharmaceuticals is $555.91, with a high forecast of $641.00 and a low forecast of $436.00.

25 Wall Street analysts have issued "buy," "hold," and "sell" ratings for Vertex Pharmaceuticals in the last year. There are currently 3 hold ratings and 22 buy ratings for the stock. The consensus among Wall Street analysts is that investors should "moderate buy" VRTX shares.

According to analysts, Vertex Pharmaceuticals's stock has a predicted upside of 30.78% based on their 12-month stock forecasts.

Over the previous 90 days, Vertex Pharmaceuticals's stock had 4 upgrades and 1 downgrade by analysts.

Analysts like Vertex Pharmaceuticals more than other "medical" companies. The consensus rating for Vertex Pharmaceuticals is Moderate Buy while the average consensus rating for "medical" companies is Hold. Learn more on how VRTX compares to other companies.


This page (NASDAQ:VRTX) was last updated on 6/2/2026 by MarketBeat.com Staff.
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